Result of FASTA (omim) for pF1KE3466
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3466, 1390 aa
  1>>>pF1KE3466     1390 - 1390 aa - 1390 aa
Library: /omim/omim.rfq.tfa
  64236559 residues in 92054 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.4867+/-0.00099; mu= -11.3727+/- 0.057
 mean_var=920.5072+/-219.500, 0's: 0 Z-trim(110.8): 1160  B-trim: 1212 in 1/48
 Lambda= 0.042273
 statistics sampled from 18674 (19995) to 18674 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.217), width:  16
 Scan time:  7.390

The best scores are:                                      opt bits E(92054)
NP_000236 (OMIM: 114550,164860,605074,607278,61670 (1390) 9334 588.3 1.4e-166
XP_011514525 (OMIM: 114550,164860,605074,607278,61 (1409) 9334 588.4 1.4e-166
NP_001311331 (OMIM: 114550,164860,605074,607278,61 ( 960) 6415 410.1 4.4e-113
XP_006716053 (OMIM: 114550,164860,605074,607278,61 ( 960) 6415 410.1 4.4e-113
NP_001311330 (OMIM: 114550,164860,605074,607278,61 ( 934) 6126 392.4 8.8e-108
NP_001120972 (OMIM: 114550,164860,605074,607278,61 (1408) 5103 330.3 6.6e-89
XP_005265227 (OMIM: 600168,617075) macrophage-stim (1401) 2164 151.1 5.9e-35
NP_002438 (OMIM: 600168,617075) macrophage-stimula (1400) 2161 150.9 6.7e-35
XP_011532044 (OMIM: 600168,617075) macrophage-stim (1324) 1754 126.0 1.9e-27
XP_011532045 (OMIM: 600168,617075) macrophage-stim (1300) 1472 108.8 2.9e-22
XP_011532046 (OMIM: 600168,617075) macrophage-stim (1295) 1467 108.5 3.6e-22
NP_001305842 (OMIM: 600168,617075) macrophage-stim (1294) 1464 108.3   4e-22
NP_001231866 (OMIM: 600168,617075) macrophage-stim (1351) 1318 99.5   2e-19
XP_011532042 (OMIM: 600168,617075) macrophage-stim (1352) 1318 99.5   2e-19
XP_011532041 (OMIM: 600168,617075) macrophage-stim (1361) 1318 99.5   2e-19
XP_011532043 (OMIM: 600168,617075) macrophage-stim (1332) 1253 95.5 3.1e-18
NP_006334 (OMIM: 604705,613862) tyrosine-protein k ( 999)  847 70.5 7.5e-11
NP_001265528 (OMIM: 109135,146110) tyrosine-protei ( 626)  793 66.9 5.7e-10
NP_001690 (OMIM: 109135,146110) tyrosine-protein k ( 885)  793 67.2 6.9e-10
NP_068713 (OMIM: 109135,146110) tyrosine-protein k ( 894)  793 67.2 6.9e-10
NP_001005861 (OMIM: 600524) tyrosine-protein kinas ( 610)  733 63.2 7.2e-09
NP_002949 (OMIM: 600524) tyrosine-protein kinase R ( 607)  724 62.7   1e-08
XP_011519819 (OMIM: 147370,270450) insulin-like gr ( 922)  716 62.5 1.8e-08
NP_001317193 (OMIM: 600341) tyrosine-protein kinas ( 845)  714 62.3 1.9e-08
NP_006284 (OMIM: 600341) tyrosine-protein kinase r ( 890)  714 62.3   2e-08
XP_024305681 (OMIM: 147370,270450) insulin-like gr (1064)  716 62.6   2e-08
XP_011519818 (OMIM: 147370,270450) insulin-like gr (1064)  716 62.6   2e-08
XP_016877628 (OMIM: 147370,270450) insulin-like gr (1246)  716 62.7 2.1e-08
NP_001278787 (OMIM: 147370,270450) insulin-like gr (1366)  716 62.8 2.2e-08
NP_000866 (OMIM: 147370,270450) insulin-like growt (1367)  716 62.8 2.2e-08
XP_016877627 (OMIM: 147370,270450) insulin-like gr (1391)  716 62.8 2.3e-08
XP_016877625 (OMIM: 147370,270450) insulin-like gr (1392)  716 62.8 2.3e-08
XP_016877626 (OMIM: 147370,270450) insulin-like gr (1392)  716 62.8 2.3e-08
XP_011526291 (OMIM: 147670,246200,262190,609968,61 (1369)  706 62.1 3.4e-08
NP_001073285 (OMIM: 147670,246200,262190,609968,61 (1370)  706 62.1 3.4e-08
XP_011526290 (OMIM: 147670,246200,262190,609968,61 (1381)  706 62.2 3.4e-08
NP_000199 (OMIM: 147670,246200,262190,609968,61054 (1382)  706 62.2 3.5e-08
NP_001129473 (OMIM: 164690) tyrosine-protein kinas ( 542)  682 60.1 5.8e-08
NP_055030 (OMIM: 147671) insulin receptor-related  (1297)  690 61.1 6.6e-08
NP_001161711 (OMIM: 164690) tyrosine-protein kinas (1043)  687 60.8 6.6e-08
NP_001161710 (OMIM: 164690) tyrosine-protein kinas (1058)  687 60.8 6.7e-08
NP_001129472 (OMIM: 164690) tyrosine-protein kinas (1064)  687 60.8 6.7e-08
NP_001161709 (OMIM: 164690) tyrosine-protein kinas (1079)  687 60.8 6.8e-08
XP_005245145 (OMIM: 164690) tyrosine-protein kinas (1146)  687 60.9   7e-08
NP_001161708 (OMIM: 164690) tyrosine-protein kinas (1161)  687 60.9   7e-08
NP_005149 (OMIM: 164690) tyrosine-protein kinase A (1167)  687 60.9   7e-08
NP_009298 (OMIM: 164690) tyrosine-protein kinase A (1182)  687 60.9 7.1e-08
XP_016856524 (OMIM: 164690) tyrosine-protein kinas (1182)  687 60.9 7.1e-08
NP_001294960 (OMIM: 176942) tyrosine-protein kinas ( 453)  674 59.4 7.4e-08
XP_016859071 (OMIM: 600543,615515) receptor tyrosi (1116)  685 60.7 7.5e-08


>>NP_000236 (OMIM: 114550,164860,605074,607278,616705) h  (1390 aa)
 initn: 9334 init1: 9334 opt: 9334  Z-score: 3112.3  bits: 588.3 E(92054): 1.4e-166
Smith-Waterman score: 9334; 100.0% identity (100.0% similar) in 1390 aa overlap (1-1390:1-1390)

               10        20        30        40        50        60
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE3 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE3 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE3 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE3 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE3 LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE3 IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE3 CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE3 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE3 SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE3 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE3 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE3 HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD
             1330      1340      1350      1360      1370      1380

             1390
pF1KE3 TRPASFWETS
       ::::::::::
NP_000 TRPASFWETS
             1390

>>XP_011514525 (OMIM: 114550,164860,605074,607278,616705  (1409 aa)
 initn: 9334 init1: 9334 opt: 9334  Z-score: 3112.3  bits: 588.4 E(92054): 1.4e-166
Smith-Waterman score: 9334; 100.0% identity (100.0% similar) in 1390 aa overlap (1-1390:20-1409)

                                  10        20        30        40 
pF1KE3                    MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
                          :::::::::::::::::::::::::::::::::::::::::
XP_011 MKSKSKSLAECFPYDKPLIMKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
               10        20        30        40        50        60

              50        60        70        80        90       100 
pF1KE3 QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
               70        80        90       100       110       120

             110       120       130       140       150       160 
pF1KE3 SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
              130       140       150       160       170       180

             170       180       190       200       210       220 
pF1KE3 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
              190       200       210       220       230       240

             230       240       250       260       270       280 
pF1KE3 TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
              250       260       270       280       290       300

             290       300       310       320       330       340 
pF1KE3 CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
              310       320       330       340       350       360

             350       360       370       380       390       400 
pF1KE3 LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
              370       380       390       400       410       420

             410       420       430       440       450       460 
pF1KE3 LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
              430       440       450       460       470       480

             470       480       490       500       510       520 
pF1KE3 FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCR
              490       500       510       520       530       540

             530       540       550       560       570       580 
pF1KE3 HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
              550       560       570       580       590       600

             590       600       610       620       630       640 
pF1KE3 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
              610       620       630       640       650       660

             650       660       670       680       690       700 
pF1KE3 NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
              670       680       690       700       710       720

             710       720       730       740       750       760 
pF1KE3 VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTIT
              730       740       750       760       770       780

             770       780       790       800       810       820 
pF1KE3 GVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
              790       800       810       820       830       840

             830       840       850       860       870       880 
pF1KE3 MLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
              850       860       870       880       890       900

             890       900       910       920       930       940 
pF1KE3 CENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI
              910       920       930       940       950       960

             950       960       970       980       990      1000 
pF1KE3 STALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
              970       980       990      1000      1010      1020

            1010      1020      1030      1040      1050      1060 
pF1KE3 DYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPE
             1030      1040      1050      1060      1070      1080

            1070      1080      1090      1100      1110      1120 
pF1KE3 LVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEV
             1090      1100      1110      1120      1130      1140

            1130      1140      1150      1160      1170      1180 
pF1KE3 SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
             1150      1160      1170      1180      1190      1200

            1190      1200      1210      1220      1230      1240 
pF1KE3 IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
             1210      1220      1230      1240      1250      1260

            1250      1260      1270      1280      1290      1300 
pF1KE3 GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
             1270      1280      1290      1300      1310      1320

            1310      1320      1330      1340      1350      1360 
pF1KE3 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
             1330      1340      1350      1360      1370      1380

            1370      1380      1390
pF1KE3 VAPYPSLLSSEDNADDEVDTRPASFWETS
       :::::::::::::::::::::::::::::
XP_011 VAPYPSLLSSEDNADDEVDTRPASFWETS
             1390      1400         

>>NP_001311331 (OMIM: 114550,164860,605074,607278,616705  (960 aa)
 initn: 6415 init1: 6415 opt: 6415  Z-score: 2151.8  bits: 410.1 E(92054): 4.4e-113
Smith-Waterman score: 6415; 100.0% identity (100.0% similar) in 960 aa overlap (431-1390:1-960)

              410       420       430       440       450       460
pF1KE3 TLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEG
                                     ::::::::::::::::::::::::::::::
NP_001                               MGQFSEVLLTSISTFIKGDLTIANLGTSEG
                                             10        20        30

              470       480       490       500       510       520
pF1KE3 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
               40        50        60        70        80        90

              530       540       550       560       570       580
pF1KE3 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
              100       110       120       130       140       150

              590       600       610       620       630       640
pF1KE3 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
              160       170       180       190       200       210

              650       660       670       680       690       700
pF1KE3 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
              220       230       240       250       260       270

              710       720       730       740       750       760
pF1KE3 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
              280       290       300       310       320       330

              770       780       790       800       810       820
pF1KE3 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
              340       350       360       370       380       390

              830       840       850       860       870       880
pF1KE3 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
              400       410       420       430       440       450

              890       900       910       920       930       940
pF1KE3 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
              460       470       480       490       500       510

              950       960       970       980       990      1000
pF1KE3 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
              520       530       540       550       560       570

             1010      1020      1030      1040      1050      1060
pF1KE3 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
              580       590       600       610       620       630

             1070      1080      1090      1100      1110      1120
pF1KE3 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
              640       650       660       670       680       690

             1130      1140      1150      1160      1170      1180
pF1KE3 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
              700       710       720       730       740       750

             1190      1200      1210      1220      1230      1240
pF1KE3 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
              760       770       780       790       800       810

             1250      1260      1270      1280      1290      1300
pF1KE3 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
              820       830       840       850       860       870

             1310      1320      1330      1340      1350      1360
pF1KE3 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
              880       890       900       910       920       930

             1370      1380      1390
pF1KE3 CVAPYPSLLSSEDNADDEVDTRPASFWETS
       ::::::::::::::::::::::::::::::
NP_001 CVAPYPSLLSSEDNADDEVDTRPASFWETS
              940       950       960

>>XP_006716053 (OMIM: 114550,164860,605074,607278,616705  (960 aa)
 initn: 6415 init1: 6415 opt: 6415  Z-score: 2151.8  bits: 410.1 E(92054): 4.4e-113
Smith-Waterman score: 6415; 100.0% identity (100.0% similar) in 960 aa overlap (431-1390:1-960)

              410       420       430       440       450       460
pF1KE3 TLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEG
                                     ::::::::::::::::::::::::::::::
XP_006                               MGQFSEVLLTSISTFIKGDLTIANLGTSEG
                                             10        20        30

              470       480       490       500       510       520
pF1KE3 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
               40        50        60        70        80        90

              530       540       550       560       570       580
pF1KE3 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
              100       110       120       130       140       150

              590       600       610       620       630       640
pF1KE3 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
              160       170       180       190       200       210

              650       660       670       680       690       700
pF1KE3 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
              220       230       240       250       260       270

              710       720       730       740       750       760
pF1KE3 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
              280       290       300       310       320       330

              770       780       790       800       810       820
pF1KE3 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
              340       350       360       370       380       390

              830       840       850       860       870       880
pF1KE3 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
              400       410       420       430       440       450

              890       900       910       920       930       940
pF1KE3 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
              460       470       480       490       500       510

              950       960       970       980       990      1000
pF1KE3 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
              520       530       540       550       560       570

             1010      1020      1030      1040      1050      1060
pF1KE3 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
              580       590       600       610       620       630

             1070      1080      1090      1100      1110      1120
pF1KE3 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
              640       650       660       670       680       690

             1130      1140      1150      1160      1170      1180
pF1KE3 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
              700       710       720       730       740       750

             1190      1200      1210      1220      1230      1240
pF1KE3 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
              760       770       780       790       800       810

             1250      1260      1270      1280      1290      1300
pF1KE3 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
              820       830       840       850       860       870

             1310      1320      1330      1340      1350      1360
pF1KE3 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
              880       890       900       910       920       930

             1370      1380      1390
pF1KE3 CVAPYPSLLSSEDNADDEVDTRPASFWETS
       ::::::::::::::::::::::::::::::
XP_006 CVAPYPSLLSSEDNADDEVDTRPASFWETS
              940       950       960

>>NP_001311330 (OMIM: 114550,164860,605074,607278,616705  (934 aa)
 initn: 6126 init1: 6126 opt: 6126  Z-score: 2056.6  bits: 392.4 E(92054): 8.8e-108
Smith-Waterman score: 6126; 100.0% identity (100.0% similar) in 910 aa overlap (1-910:1-910)

               10        20        30        40        50        60
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE3 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE3 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE3 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE3 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE3 LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
       ::::::::::                                                  
NP_001 LKLNSELNIEVGFLHSSHDVNKEASVIMLFSGLK                          
              910       920       930                              

>>NP_001120972 (OMIM: 114550,164860,605074,607278,616705  (1408 aa)
 initn: 5103 init1: 5103 opt: 5103  Z-score: 1717.8  bits: 330.3 E(92054): 6.6e-89
Smith-Waterman score: 9288; 98.7% identity (98.7% similar) in 1408 aa overlap (1-1390:1-1408)

               10        20        30        40        50        60
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE3 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
              670       680       690       700       710       720

              730       740       750                         760  
pF1KE3 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS------------------GGSTITG
       :::::::::::::::::::::::::::::::::::                  :::::::
NP_001 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG
              730       740       750       760       770       780

            770       780       790       800       810       820  
pF1KE3 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
              790       800       810       820       830       840

            830       840       850       860       870       880  
pF1KE3 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
              850       860       870       880       890       900

            890       900       910       920       930       940  
pF1KE3 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
              910       920       930       940       950       960

            950       960       970       980       990      1000  
pF1KE3 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
              970       980       990      1000      1010      1020

           1010      1020      1030      1040      1050      1060  
pF1KE3 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
             1030      1040      1050      1060      1070      1080

           1070      1080      1090      1100      1110      1120  
pF1KE3 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
             1090      1100      1110      1120      1130      1140

           1130      1140      1150      1160      1170      1180  
pF1KE3 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
             1150      1160      1170      1180      1190      1200

           1190      1200      1210      1220      1230      1240  
pF1KE3 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
             1210      1220      1230      1240      1250      1260

           1250      1260      1270      1280      1290      1300  
pF1KE3 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
             1270      1280      1290      1300      1310      1320

           1310      1320      1330      1340      1350      1360  
pF1KE3 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
             1330      1340      1350      1360      1370      1380

           1370      1380      1390
pF1KE3 APYPSLLSSEDNADDEVDTRPASFWETS
       ::::::::::::::::::::::::::::
NP_001 APYPSLLSSEDNADDEVDTRPASFWETS
             1390      1400        

>>XP_005265227 (OMIM: 600168,617075) macrophage-stimulat  (1401 aa)
 initn: 2228 init1: 1269 opt: 2164  Z-score: 749.1  bits: 151.1 E(92054): 5.9e-35
Smith-Waterman score: 2597; 34.9% identity (61.9% similar) in 1411 aa overlap (7-1359:7-1364)

               10        20           30        40        50       
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
             :  ..:.::.  .. . ::   : ..   .  . ..:: .:.:.:   .: .. 
XP_005 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
               10        20        30        40        50        60

        60             70        80        90       100       110  
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
       .:       .:..  : ..::.  ::..:    :::. . : :  :  :.   .   :  
XP_005 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
               70        80         90        100       110        

            120       130       140       150       160       170  
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
        :. . .::.:      :.::::  .: :  : .  . ::   .   :.:: . ..:..:
XP_005 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
         120       130        140       150       160       170    

            180       190       200       210       220         230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
       ::::.: ::..:    . .   :.:.......   .   .:.:.::::   .::   :..
XP_005 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
          180       190       200       210       220       230    

              240       250       260         270       280        
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
           ..:::.   :: :.:::.:... :.::::::  ..  : ...:::. :. . .  :
XP_005 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
              240       250       260       270       280       290

      290       300       310         320       330       340      
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
        .: :. :.: .. ::..:.. .  . . .:..:. .  ::::: ... . ....:::::
XP_005 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
              300       310       320       330       340       350

        350       360       370       380                   390    
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
       . .:  .      :..:::::    :... .....  ::            :. : .:. 
XP_005 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSF
              360       370           380       390       400      

          400       410       420       430       440       450    
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
         : :   :.  :   . : ..    .....::::: : .. : .:.. .    ..:.:.
XP_005 --CPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
          410       420        430       440       450       460   

          460       470        480         490       500       510 
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
       .:: .::..:: . ::     .: :: : :: .::. .:        . . :  .: .. 
XP_005 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
           470       480       490       500            510        

             520       530       540       550       560       570 
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
       ..:..: ::::: .:..:: :  :. :::: . : ...::  :.: :. : : . .  :.
XP_005 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
      520       530       540       550        560       570       

             580       590       600       610                 620 
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
       :.::.:.::::.:: .: .. ..       .: .:.  :    ..:.          .. 
XP_005 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
       580       590       600       610       620       630       

             630          640               650       660       670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
       ..: . :  ..     :.:. ..:   :.     ::.    ::...::. ...: .:: :
XP_005 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
       640       650       660       670       680       690       

              680       690       700       710       720       730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
       ::: ::: :. :. :.:: . ..:  : :  ::.. : : ::  .  .   ..:..  :.
XP_005 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
       700       710       720       730       740       750       

               740       750       760       770       780         
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
          :  :.:::::.:  : :. ..:.  : ::  :..:.:.   ..:.. :.. :     
XP_005 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
       760       770       780         790         800       810   

     790       800       810       820       830       840         
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
         .:.  :   :  :     . :  .  .     ::  .  .  .    :   :  . : 
XP_005 QCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
           820       830       840       850       860       870   

     850        860       870       880       890       900        
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
       ..  .. . .:  :     . : :  . ::..::.. ..... :.: .: .:   ..   
XP_005 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
           880       890        900        910       920       930 

      910       920            930       940       950       960   
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
       ..        .::.:.       :.... :..  .. . .::   : :  : . :::.  
XP_005 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
             940       950       960       970       980           

           970       980       990       1000      1010      1020  
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
                  :  :.:. :.:  ... .: . .   . :::. .    .:  .   :  
XP_005 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
                 990      1000      1010      1020         1030    

           1030      1040      1050      1060      1070      1080  
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
        :.      .  .......   :::..   :.:  :.  :.  :. :.:    ...: ..
XP_005 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
               1040      1050       1060      1070      1080       

           1090      1100      1110      1120      1130      1140  
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
       :::.:::: ::::  .:.  ..:.::.:::.:::.. .:  :: ::..:. ..:::::.:
XP_005 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
      1090      1100      1110      1120      1130      1140       

           1150      1160      1170      1180      1190      1200  
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
       .:: :  :: : :.:::: :::: .:::.  .::::::::.::::::.::.::: .::::
XP_005 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
      1150      1160      1170      1180      1190      1200       

           1210      1220      1230      1240      1250      1260  
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
       ::::::::::::.:::::::::::::. :.:::::...  :.::::::::::::: .:::
XP_005 RDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTT
      1210      1220      1230      1240      1250      1260       

           1270      1280      1290      1300      1310      1320  
pF1KE3 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
       ::::::::::::::.:::::::  .. ::.: .: ::::: ::::::: ::.:: .::. 
XP_005 KSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEA
      1270      1280      1290      1300      1310      1320       

           1330      1340      1350      1360      1370      1380  
pF1KE3 KAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTR
          .::.:  ::...  : :...:.:::.. :::.:.                       
XP_005 DPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPMPGN
      1330      1340      1350      1360      1370      1380       

           1390      
pF1KE3 PASFWETS      
                     
XP_005 VRRPRPLSEPPRPT
      1390      1400 

>>NP_002438 (OMIM: 600168,617075) macrophage-stimulating  (1400 aa)
 initn: 2293 init1: 1269 opt: 2161  Z-score: 748.1  bits: 150.9 E(92054): 6.7e-35
Smith-Waterman score: 2606; 34.9% identity (61.9% similar) in 1411 aa overlap (7-1359:7-1363)

               10        20           30        40        50       
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
             :  ..:.::.  .. . ::   : ..   .  . ..:: .:.:.:   .: .. 
NP_002 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
               10        20        30        40        50        60

        60             70        80        90       100       110  
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
       .:       .:..  : ..::.  ::..:    :::. . : :  :  :.   .   :  
NP_002 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
               70        80         90        100       110        

            120       130       140       150       160       170  
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
        :. . .::.:      :.::::  .: :  : .  . ::   .   :.:: . ..:..:
NP_002 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
         120       130        140       150       160       170    

            180       190       200       210       220         230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
       ::::.: ::..:    . .   :.:.......   .   .:.:.::::   .::   :..
NP_002 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
          180       190       200       210       220       230    

              240       250       260         270       280        
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
           ..:::.   :: :.:::.:... :.::::::  ..  : ...:::. :. . .  :
NP_002 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
              240       250       260       270       280       290

      290       300       310         320       330       340      
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
        .: :. :.: .. ::..:.. .  . . .:..:. .  ::::: ... . ....:::::
NP_002 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
              300       310       320       330       340       350

        350       360       370       380                   390    
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
       . .:  .      :..:::::    :... .....  ::            :. : .:. 
NP_002 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSF
              360       370           380       390       400      

          400       410       420       430       440       450    
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
         : :   :.  :   . : ..    .....::::: : .. : .:.. .    ..:.:.
NP_002 --CPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
          410       420        430       440       450       460   

          460       470        480         490       500       510 
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
       .:: .::..:: . ::     .: :: : :: .::. .:        . . :  .: .. 
NP_002 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
           470       480       490       500            510        

             520       530       540       550       560       570 
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
       ..:..: ::::: .:..:: :  :. :::: . : ...::  :.: :. : : . .  :.
NP_002 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
      520       530       540       550        560       570       

             580       590       600       610                 620 
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
       :.::.:.::::.:: .: .. ..       .: .:.  :    ..:.          .. 
NP_002 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
       580       590       600       610       620       630       

             630          640               650       660       670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
       ..: . :  ..     :.:. ..:   :.     ::.    ::...::. ...: .:: :
NP_002 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
       640       650       660       670       680       690       

              680       690       700       710       720       730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
       ::: ::: :. :. :.:: . ..:  : :  ::.. : : ::  .  .   ..:..  :.
NP_002 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
       700       710       720       730       740       750       

               740       750       760       770       780         
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
          :  :.:::::.:  : :. ..:.  : ::  :..:.:.   ..:.. :.. :     
NP_002 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
       760       770       780         790         800       810   

     790       800       810       820       830       840         
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
       :. :.  :   :  :     . :  .  .     ::  .  .  .    :   :  . : 
NP_002 CE-RQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
            820       830       840       850       860       870  

     850        860       870       880       890       900        
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
       ..  .. . .:  :     . : :  . ::..::.. ..... :.: .: .:   ..   
NP_002 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
            880       890        900        910       920       930

      910       920            930       940       950       960   
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
       ..        .::.:.       :.... :..  .. . .::   : :  : . :::.  
NP_002 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
              940       950       960       970       980          

           970       980       990       1000      1010      1020  
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
                  :  :.:. :.:  ... .: . .   . :::. .    .:  .   :  
NP_002 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
                  990      1000      1010      1020         1030   

           1030      1040      1050      1060      1070      1080  
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
        :.      .  .......   :::..   :.:  :.  :.  :. :.:    ...: ..
NP_002 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
                1040      1050       1060      1070      1080      

           1090      1100      1110      1120      1130      1140  
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
       :::.:::: ::::  .:.  ..:.::.:::.:::.. .:  :: ::..:. ..:::::.:
NP_002 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
       1090      1100      1110      1120      1130      1140      

           1150      1160      1170      1180      1190      1200  
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
       .:: :  :: : :.:::: :::: .:::.  .::::::::.::::::.::.::: .::::
NP_002 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
       1150      1160      1170      1180      1190      1200      

           1210      1220      1230      1240      1250      1260  
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
       ::::::::::::.:::::::::::::. :.:::::...  :.::::::::::::: .:::
NP_002 RDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTT
       1210      1220      1230      1240      1250      1260      

           1270      1280      1290      1300      1310      1320  
pF1KE3 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
       ::::::::::::::.:::::::  .. ::.: .: ::::: ::::::: ::.:: .::. 
NP_002 KSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEA
       1270      1280      1290      1300      1310      1320      

           1330      1340      1350      1360      1370      1380  
pF1KE3 KAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTR
          .::.:  ::...  : :...:.:::.. :::.:.                       
NP_002 DPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPMPGN
       1330      1340      1350      1360      1370      1380      

           1390      
pF1KE3 PASFWETS      
                     
NP_002 VRRPRPLSEPPRPT
       1390      1400

>>XP_011532044 (OMIM: 600168,617075) macrophage-stimulat  (1324 aa)
 initn: 1832 init1: 873 opt: 1754  Z-score: 614.2  bits: 126.0 E(92054): 1.9e-27
Smith-Waterman score: 2187; 33.2% identity (60.5% similar) in 1318 aa overlap (7-1266:7-1271)

               10        20           30        40        50       
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
             :  ..:.::.  .. . ::   : ..   .  . ..:: .:.:.:   .: .. 
XP_011 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
               10        20        30        40        50        60

        60             70        80        90       100       110  
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
       .:       .:..  : ..::.  ::..:    :::. . : :  :  :.   .   :  
XP_011 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
               70        80         90        100       110        

            120       130       140       150       160       170  
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
        :. . .::.:      :.::::  .: :  : .  . ::   .   :.:: . ..:..:
XP_011 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
         120       130        140       150       160       170    

            180       190       200       210       220         230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
       ::::.: ::..:    . .   :.:.......   .   .:.:.::::   .::   :..
XP_011 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
          180       190       200       210       220       230    

              240       250       260         270       280        
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
           ..:::.   :: :.:::.:... :.::::::  ..  : ...:::. :. . .  :
XP_011 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
              240       250       260       270       280       290

      290       300       310         320       330       340      
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
        .: :. :.: .. ::..:.. .  . . .:..:. .  ::::: ... . ....:::::
XP_011 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
              300       310       320       330       340       350

        350       360       370       380                   390    
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
       . .:  .      :..:::::    :... .....  ::            :. : .:. 
XP_011 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSF
              360       370           380       390       400      

          400       410       420       430       440       450    
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
         : :   :.  :   . : ..    .....::::: : .. : .:.. .    ..:.:.
XP_011 --CPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
          410       420        430       440       450       460   

          460       470        480         490       500       510 
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
       .:: .::..:: . ::     .: :: : :: .::. .:        . . :  .: .. 
XP_011 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
           470       480       490       500            510        

             520       530       540       550       560       570 
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
       ..:..: ::::: .:..:: :  :. :::: . : ...::  :.: :. : : . .  :.
XP_011 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
      520       530       540       550        560       570       

             580       590       600       610                 620 
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
       :.::.:.::::.:: .: .. ..       .: .:.  :    ..:.          .. 
XP_011 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
       580       590       600       610       620       630       

             630          640               650       660       670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
       ..: . :  ..     :.:. ..:   :.     ::.    ::...::. ...: .:: :
XP_011 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
       640       650       660       670       680       690       

              680       690       700       710       720       730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
       ::: ::: :. :. :.:: . ..:  : :  ::.. : : ::  .  .   ..:..  :.
XP_011 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
       700       710       720       730       740       750       

               740       750       760       770       780         
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
          :  :.:::::.:  : :. ..:.  : ::  :..:.:.   ..:.. :.. :     
XP_011 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
       760       770       780         790         800       810   

     790       800       810       820       830       840         
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
         .:.  :   :  :     . :  .  .     ::  .  .  .    :   :  . : 
XP_011 QCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
           820       830       840       850       860       870   

     850        860       870       880       890       900        
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
       ..  .. . .:  :     . : :  . ::..::.. ..... :.: .: .:   ..   
XP_011 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
           880       890        900        910       920       930 

      910       920            930       940       950       960   
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
       ..        .::.:.       :.... :..  .. . .::   : :  : . :::.  
XP_011 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
             940       950       960       970       980           

           970       980       990       1000      1010      1020  
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
                  :  :.:. :.:  ... .: . .   . :::. .    .:  .   :  
XP_011 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
                 990      1000      1010      1020         1030    

           1030      1040      1050      1060      1070      1080  
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
        :.      .  .......   :::..   :.:  :.  :.  :. :.:    ...: ..
XP_011 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
               1040      1050       1060      1070      1080       

           1090      1100      1110      1120      1130      1140  
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
       :::.:::: ::::  .:.  ..:.::.:::.:::.. .:  :: ::..:. ..:::::.:
XP_011 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
      1090      1100      1110      1120      1130      1140       

           1150      1160      1170      1180      1190      1200  
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
       .:: :  :: : :.:::: :::: .:::.  .::::::::.::::::.::.::: .::::
XP_011 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
      1150      1160      1170      1180      1190      1200       

           1210      1220      1230      1240      1250      1260  
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
       ::::::::::::.:::::::::::::. :.:::::...  :.::::::::::::: .:::
XP_011 RDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTT
      1210      1220      1230      1240      1250      1260       

           1270      1280      1290      1300      1310      1320  
pF1KE3 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
       ::::                                                        
XP_011 KSDVVPSDAAMLGGRPSSATHLQSTSGGGGADSVCTAWGPLCAAASNLHELGPQHLA   
      1270      1280      1290      1300      1310      1320       

>>XP_011532045 (OMIM: 600168,617075) macrophage-stimulat  (1300 aa)
 initn: 1693 init1: 591 opt: 1472  Z-score: 521.3  bits: 108.8 E(92054): 2.9e-22
Smith-Waterman score: 1905; 31.4% identity (59.3% similar) in 1263 aa overlap (7-1211:7-1216)

               10        20           30        40        50       
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
             :  ..:.::.  .. . ::   : ..   .  . ..:: .:.:.:   .: .. 
XP_011 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
               10        20        30        40        50        60

        60             70        80        90       100       110  
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
       .:       .:..  : ..::.  ::..:    :::. . : :  :  :.   .   :  
XP_011 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
               70        80         90        100       110        

            120       130       140       150       160       170  
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
        :. . .::.:      :.::::  .: :  : .  . ::   .   :.:: . ..:..:
XP_011 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
         120       130        140       150       160       170    

            180       190       200       210       220         230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
       ::::.: ::..:    . .   :.:.......   .   .:.:.::::   .::   :..
XP_011 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
          180       190       200       210       220       230    

              240       250       260         270       280        
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
           ..:::.   :: :.:::.:... :.::::::  ..  : ...:::. :. . .  :
XP_011 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
              240       250       260       270       280       290

      290       300       310         320       330       340      
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
        .: :. :.: .. ::..:.. .  . . .:..:. .  ::::: ... . ....:::::
XP_011 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
              300       310       320       330       340       350

        350       360       370       380                   390    
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
       . .:  .      :..:::::    :... .....  ::            :. : .:. 
XP_011 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPS-
              360       370           380       390       400      

          400       410       420       430       440       450    
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
         : :   :.  :   . : ..    .....::::: : .. : .:.. .    ..:.:.
XP_011 -FCPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
          410       420        430       440       450       460   

          460       470        480         490       500       510 
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
       .:: .::..:: . ::     .: :: : :: .::. .:     :..  . :  .: .. 
XP_011 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDV---SRLGD--HLLFASGDQVF
           470       480       490       500            510        

             520       530       540       550       560       570 
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
       ..:..: ::::: .:..:: :  :. :::: . : ...::  :.: :. : : . .  :.
XP_011 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
      520       530       540       550        560       570       

             580       590       600       610                 620 
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
       :.::.:.::::.:: .: .. ..       .: .:.  :    ..:.          .. 
XP_011 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
       580       590       600       610       620       630       

             630          640               650       660       670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
       ..: . :  ..     :.:. ..:   :.     ::.    ::...::. ...: .:: :
XP_011 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
       640       650       660       670       680       690       

              680       690       700       710       720       730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
       ::: ::: :. :. :.:: . ..:  : :  ::.. : : ::  .  .   ..:..  :.
XP_011 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
       700       710       720       730       740       750       

               740       750       760       770       780         
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
          :  :.:::::.:  : :. ..:.  : ::  :..:.:.   ..:.. :.. :     
XP_011 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
       760       770       780         790         800       810   

     790       800       810       820       830       840         
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
         .:.  :   :  :     . :  .  .     ::  .  .  .    :   :  . : 
XP_011 QCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
           820       830       840       850       860       870   

     850        860       870       880       890       900        
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
       ..  .. . .:  :     . : :  . ::..::.. ..... :.: .: .:   ..   
XP_011 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
           880       890        900        910       920       930 

      910       920            930       940       950       960   
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
       ..        .::.:.       :.... :..  .. . .::   : :  : . :::.  
XP_011 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
             940       950       960       970       980           

           970       980       990       1000      1010      1020  
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
                  :  :.:. :.:  ... .: . .   . :::. .    .:  .   :  
XP_011 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
                 990      1000      1010      1020         1030    

           1030      1040      1050      1060      1070      1080  
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
        :.      .  .......   :::..   :.:  :.  :.  :. :.:    ...: ..
XP_011 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
               1040      1050       1060      1070      1080       

           1090      1100      1110      1120      1130      1140  
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
       :::.:::: ::::  .:.  ..:.::.:::.:::.. .:  :: ::..:. ..:::::.:
XP_011 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
      1090      1100      1110      1120      1130      1140       

           1150      1160      1170      1180      1190      1200  
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
       .:: :  :: : :.:::: :::: .:::.  .::::::::.::::::.::.::: .::::
XP_011 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
      1150      1160      1170      1180      1190      1200       

           1210      1220      1230      1240      1250      1260  
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
       :::::::::                                                   
XP_011 RDLAARNCMYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPST
      1210      1220      1230      1240      1250      1260       




1390 residues in 1 query   sequences
64236559 residues in 92054 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Aug  1 17:00:18 2019 done: Thu Aug  1 17:00:19 2019
 Total Scan time:  7.390 Total Display time:  0.380

Function used was FASTA [36.3.4 Apr, 2011]
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