Result of FASTA (omim) for pF1KE1851
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1851, 370 aa
  1>>>pF1KE1851     370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
  64092750 residues in 91774 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7800+/-0.000289; mu= 20.4877+/- 0.018
 mean_var=75.8850+/-14.924, 0's: 0 Z-trim(119.0): 65  B-trim: 0 in 0/52
 Lambda= 0.147230
 statistics sampled from 33640 (33707) to 33640 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.367), width:  16
 Scan time:  4.320

The best scores are:                                      opt bits E(91774)
NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 2644 570.6 2.2e-162
NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 1136 250.3 5.6e-66
NP_149122 (OMIM: 606359) protein Wnt-3a precursor  ( 352) 1120 246.9 5.8e-65
XP_011542621 (OMIM: 606359) protein Wnt-3a isoform ( 446) 1120 247.0 6.9e-65
NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 1109 244.5 2.9e-64
XP_011539899 (OMIM: 158330,603490,611812) protein  ( 373) 1106 243.9 4.8e-64
XP_011539900 (OMIM: 158330,603490,611812) protein  ( 296) 1092 240.8 3.2e-63
NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349)  981 217.3 4.5e-56
NP_478679 (OMIM: 601967) protein Wnt-7b precursor  ( 349)  976 216.3 9.3e-56
XP_011528668 (OMIM: 601967) protein Wnt-7b isoform ( 353)  976 216.3 9.4e-56
NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2  ( 355)  966 214.2 4.1e-55
NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1  ( 365)  966 214.2 4.2e-55
XP_011532393 (OMIM: 228930,276820,601570) protein  ( 282)  949 210.4 4.3e-54
XP_005274288 (OMIM: 603699) protein Wnt-11 isoform ( 354)  880 195.9 1.3e-49
NP_004617 (OMIM: 603699) protein Wnt-11 precursor  ( 354)  880 195.9 1.3e-49
NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3  ( 351)  876 195.0 2.3e-49
NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369)  876 195.1 2.4e-49
XP_016865314 (OMIM: 606360) protein Wnt-8a isoform ( 391)  876 195.1 2.5e-49
NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386)  871 194.0 5.2e-49
XP_016865313 (OMIM: 606360) protein Wnt-8a isoform ( 408)  871 194.0 5.4e-49
XP_011543541 (OMIM: 603699) protein Wnt-11 isoform ( 364)  855 190.6 5.2e-48
XP_011543540 (OMIM: 603699) protein Wnt-11 isoform ( 364)  855 190.6 5.2e-48
XP_011543542 (OMIM: 603699) protein Wnt-11 isoform ( 364)  855 190.6 5.2e-48
NP_003384 (OMIM: 601396) protein Wnt-8b precursor  ( 351)  852 189.9   8e-48
NP_003386 (OMIM: 602863) protein Wnt-9a precursor  ( 365)  847 188.9 1.7e-47
NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1  ( 357)  833 185.9 1.3e-46
XP_011523480 (OMIM: 602864) protein Wnt-9b isoform ( 363)  830 185.3 2.1e-46
XP_011542573 (OMIM: 602863) protein Wnt-9a isoform ( 295)  804 179.7 8.3e-45
XP_024304972 (OMIM: 606361) protein Wnt-5b isoform ( 380)  759 170.2 7.4e-42
XP_024304971 (OMIM: 606361) protein Wnt-5b isoform ( 411)  759 170.2 7.9e-42
XP_011541927 (OMIM: 606360) protein Wnt-8a isoform ( 337)  756 169.5 1.1e-41
NP_116031 (OMIM: 606361) protein Wnt-5b precursor  ( 359)  746 167.4 4.8e-41
NP_110402 (OMIM: 606361) protein Wnt-5b precursor  ( 359)  746 167.4 4.8e-41
XP_024304974 (OMIM: 606361) protein Wnt-5b isoform ( 359)  746 167.4 4.8e-41
XP_024304973 (OMIM: 606361) protein Wnt-5b isoform ( 359)  746 167.4 4.8e-41
XP_024304975 (OMIM: 606361) protein Wnt-5b isoform ( 359)  746 167.4 4.8e-41
XP_024304976 (OMIM: 606361) protein Wnt-5b isoform ( 359)  746 167.4 4.8e-41
XP_024304977 (OMIM: 606361) protein Wnt-5b isoform ( 359)  746 167.4 4.8e-41
NP_004176 (OMIM: 601968,618168) protein Wnt-2b iso ( 372)  746 167.4   5e-41
NP_078613 (OMIM: 601968,618168) protein Wnt-2b iso ( 391)  746 167.5 5.1e-41
XP_011532391 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
XP_011532388 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
XP_006713387 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
XP_016862617 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
XP_011532389 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
XP_011532387 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
XP_011532390 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
NP_001243034 (OMIM: 164975,180700) protein Wnt-5a  ( 365)  743 166.8 7.6e-41
NP_003383 (OMIM: 164975,180700) protein Wnt-5a iso ( 380)  743 166.8 7.8e-41
XP_016862616 (OMIM: 164975,180700) protein Wnt-5a  ( 394)  743 166.8   8e-41


>>NP_005421 (OMIM: 164820,615220,615221) proto-oncogene   (370 aa)
 initn: 2644 init1: 2644 opt: 2644  Z-score: 3037.0  bits: 570.6 E(91774): 2.2e-162
Smith-Waterman score: 2644; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)

               10        20        30        40        50        60
pF1KE1 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 CRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 GREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 AVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 YSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNC
              310       320       330       340       350       360

              370
pF1KE1 THTRVLHECL
       ::::::::::
NP_005 THTRVLHECL
              370

>>NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt-3 p  (355 aa)
 initn: 1107 init1: 597 opt: 1136  Z-score: 1306.1  bits: 250.3 E(91774): 5.6e-66
Smith-Waterman score: 1136; 46.0% identity (71.8% similar) in 337 aa overlap (34-369:26-354)

            10        20        30        40        50        60   
pF1KE1 WALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPSLQL
                                     ::...   . :.: .     : .:  :.  
NP_110      MEPHLLGLLLGLLLGGTRVLAGYPIWWSLALGQQYTSLGS-----QPLLCGSIPG
                    10        20        30        40             50

            70        80        90       100       110        120  
pF1KE1 LSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGP-HLFGKIVNRGCR
       :  :: :. :.   :. ::. :.. ...::. :::.::::: :      .:: ..... :
NP_110 LVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATR
               60        70        80        90       100       110

            130       140       150       160       170       180  
pF1KE1 ETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGR
       :.::. ::.::::. .:.:::.::.   : :: ...:: :  :.:::::.. ::: : .:
NP_110 ESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSR
              120       130       140       150       160       170

            190       200       210       220       230       240  
pF1KE1 EFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAV
       ::.:. :.  : :  :: :::::::::....:. .:::::.:::: :.:::   : .::.
NP_110 EFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAI
              180       190       200       210       220       230

            250       260       270       280       290       300  
pF1KE1 GDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYS
       :: :.:..:.::...     ..: ::. .  :. .    :::. .::::.:.:::::  .
NP_110 GDFLKDKYDSASEMVV---EKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPN
              240          250       260       270       280       

            310       320       330       340       350       360  
pF1KE1 GRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNCTH
        . :. ::  :.:: .: ..:::.:::::::: :::..  :.:.: :::::.:::..: .
NP_110 PETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIR
       290       300       310       320       330       340       

            370
pF1KE1 TRVLHECL
          .: : 
NP_110 IYDVHTCK
       350     

>>NP_149122 (OMIM: 606359) protein Wnt-3a precursor [Hom  (352 aa)
 initn: 1089 init1: 574 opt: 1120  Z-score: 1287.8  bits: 246.9 E(91774): 5.8e-65
Smith-Waterman score: 1120; 44.5% identity (70.7% similar) in 355 aa overlap (16-369:7-351)

               10        20        30        40        50        60
pF1KE1 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
                      .: : .:  ::  .:   ::...   . ..: .     : .:  :
NP_149          MAPLGYFLLLCSLKQAL--GSYPIWWSLAVGPQYSSLGS-----QPILCAS
                        10          20        30             40    

               70        80        90       100       110          
pF1KE1 LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGP-HLFGKIVNR
       .  :  :: :. :.   :. ::. :.. ...::. :::.::::: :.     .:: ....
NP_149 IPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDK
           50        60        70        80        90       100    

     120       130       140       150       160       170         
pF1KE1 GCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRL
       . ::.::. ::.::::. .:.:::.::.   : :. :..:  :  :.:::::..:.:: .
NP_149 ATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGM
          110       120       130       140       150       160    

     180       190       200       210       220       230         
pF1KE1 FGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTL
        .:::.:. :.  : :  :: ::::::: .. :.:. .:::::.:::: :.:::   : .
NP_149 VSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDF
          170       180       190       200       210       220    

     240       250       260       270       280       290         
pF1KE1 RAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFC
       ::.:: :.:..:.::...  .   .: ::. .  :.:.    : :. .::::.: :::::
NP_149 RAIGDFLKDKYDSASEMVVEK---HRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFC
          230       240          250       260       270       280 

     300       310       320       330       340       350         
pF1KE1 TYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRN
         . . :. ::  :.:: :: ..:::.:::::::: .:..:  :.: :.:::::.:::..
NP_149 EPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQE
             290       300       310       320       330       340 

     360       370
pF1KE1 CTHTRVLHECL
       ::..  .: : 
NP_149 CTRVYDVHTCK
             350  

>>XP_011542621 (OMIM: 606359) protein Wnt-3a isoform X1   (446 aa)
 initn: 1089 init1: 574 opt: 1120  Z-score: 1286.5  bits: 247.0 E(91774): 6.9e-65
Smith-Waterman score: 1120; 44.5% identity (70.7% similar) in 355 aa overlap (16-369:7-351)

               10        20        30        40        50        60
pF1KE1 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
                      .: : .:  ::  .:   ::...   . ..: .     : .:  :
XP_011          MAPLGYFLLLCSLKQAL--GSYPIWWSLAVGPQYSSLGS-----QPILCAS
                        10          20        30             40    

               70        80        90       100       110          
pF1KE1 LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGP-HLFGKIVNR
       .  :  :: :. :.   :. ::. :.. ...::. :::.::::: :.     .:: ....
XP_011 IPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDK
           50        60        70        80        90       100    

     120       130       140       150       160       170         
pF1KE1 GCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRL
       . ::.::. ::.::::. .:.:::.::.   : :. :..:  :  :.:::::..:.:: .
XP_011 ATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGM
          110       120       130       140       150       160    

     180       190       200       210       220       230         
pF1KE1 FGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTL
        .:::.:. :.  : :  :: ::::::: .. :.:. .:::::.:::: :.:::   : .
XP_011 VSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDF
          170       180       190       200       210       220    

     240       250       260       270       280       290         
pF1KE1 RAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFC
       ::.:: :.:..:.::...  .   .: ::. .  :.:.    : :. .::::.: :::::
XP_011 RAIGDFLKDKYDSASEMVVEK---HRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFC
          230       240          250       260       270       280 

     300       310       320       330       340       350         
pF1KE1 TYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRN
         . . :. ::  :.:: :: ..:::.:::::::: .:..:  :.: :.:::::.:::..
XP_011 EPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQE
             290       300       310       320       330       340 

     360       370                                                 
pF1KE1 CTHTRVLHECL                                                 
       ::..  .: :                                                  
XP_011 CTRVYDVHTCKPCHSWATGREGRRRWSTLGCGPRDGCLRTGHSGPCRSLAWIWSPGSQGH
             350       360       370       380       390       400 

>>NP_110388 (OMIM: 158330,603490,611812) protein Wnt-4 p  (351 aa)
 initn: 1111 init1: 413 opt: 1109  Z-score: 1275.2  bits: 244.5 E(91774): 2.9e-64
Smith-Waterman score: 1113; 45.4% identity (70.6% similar) in 357 aa overlap (16-369:12-350)

               10        20        30        40        50        60
pF1KE1 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
                      ::..:.. :: :.:     :  .   ::.. ... .. .     .
NP_110     MSPRSCLRSLRLLVFAVFSAA-ASN-----WLYLAKLSSVGSISEEETCE-----K
                   10        20              30        40          

               70        80        90       100       110       120
pF1KE1 LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRG
       :. : ..: .. ..:  .. ::  : : :..::..::::::::: :  .  .:::.:..:
NP_110 LKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQG
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KE1 CRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLF
        ::.::..::.::::. .:.:.:: : .:.: ::   .: .   ..:.:::::: .:  :
NP_110 TREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAF
         110       120       130       140       150       160     

              190          200       210       220       230       
pF1KE1 GREFVDSGEKGRDL---RFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLP
       .. :::  :...     : ::::::::::: .....:: ::::::.:::: :.:::  .:
NP_110 SQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVP
         170       180       190       200       210       220     

       240       250       260       270       280       290       
pF1KE1 TLRAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPN
        .: :: .:...::::..:     ::.::       : :..   :: . .::::.: ::.
NP_110 PFRQVGHALKEKFDGATEVEPRRVGSSRA-------LVPRNAQFKPHTDEDLVYLEPSPD
         230       240       250              260       270        

       300       310       320       330       340       350       
pF1KE1 FCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSC
       ::  . : :. :: ::.::..: :.::::::::::: .:   ...:::.: ::::: :.:
NP_110 FCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKC
      280       290       300       310       320       330        

       360       370
pF1KE1 RNCTHTRVLHECL
       :.: .   :: : 
NP_110 RQCQRLVELHTCR
      340       350 

>>XP_011539899 (OMIM: 158330,603490,611812) protein Wnt-  (373 aa)
 initn: 1091 init1: 413 opt: 1106  Z-score: 1271.4  bits: 243.9 E(91774): 4.8e-64
Smith-Waterman score: 1106; 48.7% identity (72.8% similar) in 312 aa overlap (61-369:68-372)

               40        50        60        70        80        90
pF1KE1 SGRWWGIVNVASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAV
                                     :. : ..: .. ..:  .. ::  : : :.
XP_011 YEGEDTGHIPRYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAI
        40        50        60        70        80        90       

              100       110       120       130       140       150
pF1KE1 RECKWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIES
       .::..::::::::: :  .  .:::.:..: ::.::..::.::::. .:.:.:: : .:.
XP_011 EECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEK
       100       110       120       130       140       150       

              160       170       180       190          200       
pF1KE1 CTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDL---RFLMNLHNNEAGR
       : ::   .: .   ..:.:::::: .:  :.. :::  :...     : :::::::::::
XP_011 CGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGR
       160       170       180       190       200       210       

       210       220       230       240       250       260       
pF1KE1 TTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRAS
        .....:: ::::::.:::: :.:::  .: .: :: .:...::::..:     ::.:: 
XP_011 KAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRA-
       220       230       240       250       260       270       

       270       280       290       300       310       320       
pF1KE1 RAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCEL
             : :..   :: . .::::.: ::.::  . : :. :: ::.::..: :.:::::
XP_011 ------LVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCEL
              280       290       300       310       320       330

       330       340       350       360       370
pF1KE1 LCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
       :::::: .:   ...:::.: ::::: :.::.: .   :: : 
XP_011 LCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
              340       350       360       370   

>>XP_011539900 (OMIM: 158330,603490,611812) protein Wnt-  (296 aa)
 initn: 1111 init1: 413 opt: 1092  Z-score: 1256.6  bits: 240.8 E(91774): 3.2e-63
Smith-Waterman score: 1092; 49.3% identity (72.8% similar) in 302 aa overlap (71-369:1-295)

               50        60        70        80        90       100
pF1KE1 ASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNR
                                     . ..:  .. ::  : : :..::..:::::
XP_011                               MCKRNLEVMDSVRRGAQLAIEECQYQFRNR
                                             10        20        30

              110       120       130       140       150       160
pF1KE1 RWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGP
       :::: :  .  .:::.:..: ::.::..::.::::. .:.:.:: : .:.: ::   .: 
XP_011 RWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGV
               40        50        60        70        80        90

              170       180       190          200       210       
pF1KE1 GGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDL---RFLMNLHNNEAGRTTVFSEMRQE
       .   ..:.:::::: .:  :.. :::  :...     : ::::::::::: .....:: :
XP_011 SPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVE
              100       110       120       130       140       150

       220       230       240       250       260       270       
pF1KE1 CKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPE
       :::::.:::: :.:::  .: .: :: .:...::::..:     ::.::       : :.
XP_011 CKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRA-------LVPR
              160       170       180       190              200   

       280       290       300       310       320       330       
pF1KE1 DPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTR
       .   :: . .::::.: ::.::  . : :. :: ::.::..: :.::::::::::: .: 
XP_011 NAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTA
           210       220       230       240       250       260   

       340       350       360       370
pF1KE1 TQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
         ...:::.: ::::: :.::.: .   :: : 
XP_011 QVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
           270       280       290      

>>NP_004616 (OMIM: 228930,276820,601570) protein Wnt-7a   (349 aa)
 initn: 699 init1: 371 opt: 981  Z-score: 1128.3  bits: 217.3 E(91774): 4.5e-56
Smith-Waterman score: 981; 42.9% identity (70.5% similar) in 308 aa overlap (64-369:44-348)

            40        50        60        70        80        90   
pF1KE1 WWGIVNVASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVREC
                                     :. .:: . .. :  .  .. : : .. ::
NP_004 LSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDEC
            20        30        40        50        60        70   

           100       110       120       130       140       150   
pF1KE1 KWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTC
       ..:::: :::: .     .::: .. : ::.:: .:: .:::.:... .:..:.. .: :
NP_004 QFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGC
            80        90       100       110       120       130   

           160         170       180       190       200       210 
pF1KE1 DYRRRGPGGPD--WHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVF
       : ...:    :  :.::::: .: .:  :.. :::. :  .. : :::::::::::  . 
NP_004 DKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILE
           140       150       160       170       180       190   

             220       230       240       250       260       270 
pF1KE1 SEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAEL
        .:. ::::::.:::::..:::  :: .: .: ::.:... : .:    :.: : .:  .
NP_004 ENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHV-EPVRAS-RNKRPTF
           200       210       220       230        240        250 

             280       290       300       310       320       330 
pF1KE1 LRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCG
       :... .  ... :   ::::.:::::.:  .   :..:: :::::...:  .::.:.:::
NP_004 LKIK-KPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCG
              260       270       280       290       300       310

             340       350       360       370
pF1KE1 RGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
       ::. :.    . .::: :::::.:.: .:..   .. : 
NP_004 RGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
              320       330       340         

>>NP_478679 (OMIM: 601967) protein Wnt-7b precursor [Hom  (349 aa)
 initn: 706 init1: 378 opt: 976  Z-score: 1122.6  bits: 216.3 E(91774): 9.3e-56
Smith-Waterman score: 976; 42.5% identity (70.1% similar) in 308 aa overlap (64-369:44-348)

            40        50        60        70        80        90   
pF1KE1 WWGIVNVASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVREC
                                     :. .:: . .. :  .  .. : : .. ::
NP_478 LCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINEC
            20        30        40        50        60        70   

           100       110       120       130       140       150   
pF1KE1 KWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTC
       ..:::  :::: .     .::. .  : ::.:: .:::.:::.:.:. .::.:.. .: :
NP_478 QYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGC
            80        90       100       110       120       130   

             160       170       180       190       200       210 
pF1KE1 DYRRRG--PGGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVF
       : ...:    .  :.::::: .. .:  :.:.:::. :  .. : ::::::::::: .. 
NP_478 DREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVLE
           140       150       160       170       180       190   

             220       230       240       250       260       270 
pF1KE1 SEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAEL
       ..:. ::::::.:::::..:::  :: .: :: .:......: .:    :.: :  .  .
NP_478 DRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEV-VRAS-RLRQPTF
           200       210       220       230       240         250 

             280       290       300       310       320       330 
pF1KE1 LRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCG
       ::.. .  ... :   ::::.:::::.:  ..  :..:: :: :: .::. :::. .:::
NP_478 LRIK-QLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCG
              260       270       280       290       300       310

             340       350       360       370
pF1KE1 RGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
       ::. :.    . .::: ::::: :.: .:..   .  : 
NP_478 RGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
              320       330       340         

>>XP_011528668 (OMIM: 601967) protein Wnt-7b isoform X1   (353 aa)
 initn: 706 init1: 378 opt: 976  Z-score: 1122.5  bits: 216.3 E(91774): 9.4e-56
Smith-Waterman score: 976; 42.5% identity (70.1% similar) in 308 aa overlap (64-369:48-352)

            40        50        60        70        80        90   
pF1KE1 WWGIVNVASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVREC
                                     :. .:: . .. :  .  .. : : .. ::
XP_011 IFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINEC
        20        30        40        50        60        70       

           100       110       120       130       140       150   
pF1KE1 KWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTC
       ..:::  :::: .     .::. .  : ::.:: .:::.:::.:.:. .::.:.. .: :
XP_011 QYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGC
        80        90       100       110       120       130       

             160       170       180       190       200       210 
pF1KE1 DYRRRG--PGGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVF
       : ...:    .  :.::::: .. .:  :.:.:::. :  .. : ::::::::::: .. 
XP_011 DREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVLE
       140       150       160       170       180       190       

             220       230       240       250       260       270 
pF1KE1 SEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAEL
       ..:. ::::::.:::::..:::  :: .: :: .:......: .:    :.: :  .  .
XP_011 DRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEV-VRAS-RLRQPTF
       200       210       220       230       240         250     

             280       290       300       310       320       330 
pF1KE1 LRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCG
       ::.. .  ... :   ::::.:::::.:  ..  :..:: :: :: .::. :::. .:::
XP_011 LRIK-QLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCG
          260       270       280       290       300       310    

             340       350       360       370
pF1KE1 RGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
       ::. :.    . .::: ::::: :.: .:..   .  : 
XP_011 RGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
          320       330       340       350   




370 residues in 1 query   sequences
64092750 residues in 91774 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Jul 16 15:55:58 2019 done: Tue Jul 16 15:55:58 2019
 Total Scan time:  4.320 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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