Result of FASTA (omim) for pF1KE9645
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9645, 2492 aa
  1>>>pF1KE9645 2492 - 2492 aa - 2492 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.0757+/-0.000645; mu= -14.7792+/- 0.040
 mean_var=612.5189+/-124.711, 0's: 0 Z-trim(118.8): 249  B-trim: 0 in 0/58
 Lambda= 0.051822
 statistics sampled from 31906 (32156) to 31906 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.377), width:  16
 Scan time: 23.930

The best scores are:                                      opt bits E(85289)
NP_000480 (OMIM: 300032,300448,300504,301040,30958 (2492) 16258 1233.2       0
XP_005262210 (OMIM: 300032,300448,300504,301040,30 (2491) 16240 1231.8       0
XP_005262212 (OMIM: 300032,300448,300504,301040,30 (2453) 16014 1214.9       0
XP_016885091 (OMIM: 300032,300448,300504,301040,30 (2452) 15996 1213.6       0
XP_005262213 (OMIM: 300032,300448,300504,301040,30 (2437) 15911 1207.2       0
XP_016885092 (OMIM: 300032,300448,300504,301040,30 (2436) 15893 1205.9       0
NP_612114 (OMIM: 300032,300448,300504,301040,30958 (2454) 15259 1158.5       0
XP_006724730 (OMIM: 300032,300448,300504,301040,30 (2399) 15252 1158.0       0
XP_016885095 (OMIM: 300032,300448,300504,301040,30 (2415) 15252 1158.0       0
XP_006724729 (OMIM: 300032,300448,300504,301040,30 (2453) 15251 1157.9       0
XP_016885097 (OMIM: 300032,300448,300504,301040,30 (2398) 15244 1157.4       0
XP_016885096 (OMIM: 300032,300448,300504,301040,30 (2414) 15244 1157.4       0
XP_016885100 (OMIM: 300032,300448,300504,301040,30 (2370) 12361 941.8       0
XP_016885099 (OMIM: 300032,300448,300504,301040,30 (2385) 12361 941.8       0
XP_016885098 (OMIM: 300032,300448,300504,301040,30 (2386) 12361 941.8       0
XP_016885094 (OMIM: 300032,300448,300504,301040,30 (2424) 12361 941.8       0
XP_005262214 (OMIM: 300032,300448,300504,301040,30 (2424) 12361 941.8       0
XP_016885093 (OMIM: 300032,300448,300504,301040,30 (2425) 12361 941.8       0
XP_016885090 (OMIM: 300032,300448,300504,301040,30 (2462) 12361 941.8       0
XP_005262211 (OMIM: 300032,300448,300504,301040,30 (2463) 12361 941.8       0
XP_006724731 (OMIM: 300032,300448,300504,301040,30 (1871) 12054 918.8       0
NP_000115 (OMIM: 133540,211980,214150,278800,60063 (1493)  395 47.0  0.0022
NP_001333369 (OMIM: 133540,211980,214150,278800,60 (1493)  395 47.0  0.0022
XP_011540602 (OMIM: 114480,603615,605027) PREDICTE ( 489)  370 44.7  0.0036
XP_011540601 (OMIM: 114480,603615,605027) PREDICTE ( 489)  370 44.7  0.0036
XP_006711038 (OMIM: 114480,603615,605027) PREDICTE ( 567)  370 44.8   0.004
NP_003570 (OMIM: 114480,603615,605027) DNA repair  ( 747)  370 44.9  0.0049
NP_001136020 (OMIM: 114480,603615,605027) DNA repa ( 747)  370 44.9  0.0049


>>NP_000480 (OMIM: 300032,300448,300504,301040,309580) t  (2492 aa)
 initn: 16258 init1: 16258 opt: 16258  Z-score: 6588.2  bits: 1233.2 E(85289):    0
Smith-Waterman score: 16258; 100.0% identity (100.0% similar) in 2492 aa overlap (1-2492:1-2492)

               10        20        30        40        50        60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
             2410      2420      2430      2440      2450      2460

             2470      2480      2490  
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
       ::::::::::::::::::::::::::::::::
NP_000 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
             2470      2480      2490  

>>XP_005262210 (OMIM: 300032,300448,300504,301040,309580  (2491 aa)
 initn: 15230 init1: 15230 opt: 16240  Z-score: 6580.9  bits: 1231.8 E(85289):    0
Smith-Waterman score: 16240; 100.0% identity (100.0% similar) in 2492 aa overlap (1-2492:1-2491)

               10        20        30        40        50        60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
       ::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_005 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRG-DGLHGIVSCTACGQQVNH
              130       140       150       160        170         

              190       200       210       220       230       240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
    1080      1090      1100      1110      1120      1130         

             1150      1160      1170      1180      1190      1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
    1140      1150      1160      1170      1180      1190         

             1210      1220      1230      1240      1250      1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
    1200      1210      1220      1230      1240      1250         

             1270      1280      1290      1300      1310      1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
    1260      1270      1280      1290      1300      1310         

             1330      1340      1350      1360      1370      1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
    1320      1330      1340      1350      1360      1370         

             1390      1400      1410      1420      1430      1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
    1380      1390      1400      1410      1420      1430         

             1450      1460      1470      1480      1490      1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
    1440      1450      1460      1470      1480      1490         

             1510      1520      1530      1540      1550      1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
    1500      1510      1520      1530      1540      1550         

             1570      1580      1590      1600      1610      1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
    1560      1570      1580      1590      1600      1610         

             1630      1640      1650      1660      1670      1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
    1620      1630      1640      1650      1660      1670         

             1690      1700      1710      1720      1730      1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
    1680      1690      1700      1710      1720      1730         

             1750      1760      1770      1780      1790      1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
    1740      1750      1760      1770      1780      1790         

             1810      1820      1830      1840      1850      1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
    1800      1810      1820      1830      1840      1850         

             1870      1880      1890      1900      1910      1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
    1860      1870      1880      1890      1900      1910         

             1930      1940      1950      1960      1970      1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
    1920      1930      1940      1950      1960      1970         

             1990      2000      2010      2020      2030      2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
    1980      1990      2000      2010      2020      2030         

             2050      2060      2070      2080      2090      2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
    2040      2050      2060      2070      2080      2090         

             2110      2120      2130      2140      2150      2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
    2100      2110      2120      2130      2140      2150         

             2170      2180      2190      2200      2210      2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
    2160      2170      2180      2190      2200      2210         

             2230      2240      2250      2260      2270      2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
    2220      2230      2240      2250      2260      2270         

             2290      2300      2310      2320      2330      2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
    2280      2290      2300      2310      2320      2330         

             2350      2360      2370      2380      2390      2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
    2340      2350      2360      2370      2380      2390         

             2410      2420      2430      2440      2450      2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
    2400      2410      2420      2430      2440      2450         

             2470      2480      2490  
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
       ::::::::::::::::::::::::::::::::
XP_005 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
    2460      2470      2480      2490 

>>XP_005262212 (OMIM: 300032,300448,300504,301040,309580  (2453 aa)
 initn: 16014 init1: 16014 opt: 16014  Z-score: 6489.7  bits: 1214.9 E(85289):    0
Smith-Waterman score: 16014; 100.0% identity (100.0% similar) in 2453 aa overlap (40-2492:1-2453)

      10        20        30        40        50        60         
pF1KE9 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE
                                     ::::::::::::::::::::::::::::::
XP_005                               MNQNTDKISGSGSNSDMMENSKEEGTSSSE
                                             10        20        30

      70        80        90       100       110       120         
pF1KE9 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KE9 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
              100       110       120       130       140       150

     190       200       210       220       230       240         
pF1KE9 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
              160       170       180       190       200       210

     250       260       270       280       290       300         
pF1KE9 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
              220       230       240       250       260       270

     310       320       330       340       350       360         
pF1KE9 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
              280       290       300       310       320       330

     370       380       390       400       410       420         
pF1KE9 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
              340       350       360       370       380       390

     430       440       450       460       470       480         
pF1KE9 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
              400       410       420       430       440       450

     490       500       510       520       530       540         
pF1KE9 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
              460       470       480       490       500       510

     550       560       570       580       590       600         
pF1KE9 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
              520       530       540       550       560       570

     610       620       630       640       650       660         
pF1KE9 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
              580       590       600       610       620       630

     670       680       690       700       710       720         
pF1KE9 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
              640       650       660       670       680       690

     730       740       750       760       770       780         
pF1KE9 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
              700       710       720       730       740       750

     790       800       810       820       830       840         
pF1KE9 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
              760       770       780       790       800       810

     850       860       870       880       890       900         
pF1KE9 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
              820       830       840       850       860       870

     910       920       930       940       950       960         
pF1KE9 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
              880       890       900       910       920       930

     970       980       990      1000      1010      1020         
pF1KE9 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
              940       950       960       970       980       990

    1030      1040      1050      1060      1070      1080         
pF1KE9 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
             1000      1010      1020      1030      1040      1050

    1090      1100      1110      1120      1130      1140         
pF1KE9 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
             1060      1070      1080      1090      1100      1110

    1150      1160      1170      1180      1190      1200         
pF1KE9 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
             1120      1130      1140      1150      1160      1170

    1210      1220      1230      1240      1250      1260         
pF1KE9 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
             1180      1190      1200      1210      1220      1230

    1270      1280      1290      1300      1310      1320         
pF1KE9 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
             1240      1250      1260      1270      1280      1290

    1330      1340      1350      1360      1370      1380         
pF1KE9 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
             1300      1310      1320      1330      1340      1350

    1390      1400      1410      1420      1430      1440         
pF1KE9 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
             1360      1370      1380      1390      1400      1410

    1450      1460      1470      1480      1490      1500         
pF1KE9 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
             1420      1430      1440      1450      1460      1470

    1510      1520      1530      1540      1550      1560         
pF1KE9 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
             1480      1490      1500      1510      1520      1530

    1570      1580      1590      1600      1610      1620         
pF1KE9 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
             1540      1550      1560      1570      1580      1590

    1630      1640      1650      1660      1670      1680         
pF1KE9 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
             1600      1610      1620      1630      1640      1650

    1690      1700      1710      1720      1730      1740         
pF1KE9 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
             1660      1670      1680      1690      1700      1710

    1750      1760      1770      1780      1790      1800         
pF1KE9 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
             1720      1730      1740      1750      1760      1770

    1810      1820      1830      1840      1850      1860         
pF1KE9 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
             1780      1790      1800      1810      1820      1830

    1870      1880      1890      1900      1910      1920         
pF1KE9 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
             1840      1850      1860      1870      1880      1890

    1930      1940      1950      1960      1970      1980         
pF1KE9 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
             1900      1910      1920      1930      1940      1950

    1990      2000      2010      2020      2030      2040         
pF1KE9 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
             1960      1970      1980      1990      2000      2010

    2050      2060      2070      2080      2090      2100         
pF1KE9 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
             2020      2030      2040      2050      2060      2070

    2110      2120      2130      2140      2150      2160         
pF1KE9 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
             2080      2090      2100      2110      2120      2130

    2170      2180      2190      2200      2210      2220         
pF1KE9 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
             2140      2150      2160      2170      2180      2190

    2230      2240      2250      2260      2270      2280         
pF1KE9 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
             2200      2210      2220      2230      2240      2250

    2290      2300      2310      2320      2330      2340         
pF1KE9 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
             2260      2270      2280      2290      2300      2310

    2350      2360      2370      2380      2390      2400         
pF1KE9 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
             2320      2330      2340      2350      2360      2370

    2410      2420      2430      2440      2450      2460         
pF1KE9 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
             2380      2390      2400      2410      2420      2430

    2470      2480      2490  
pF1KE9 PPLQRAPPPMRSKNPGPSQGKSM
       :::::::::::::::::::::::
XP_005 PPLQRAPPPMRSKNPGPSQGKSM
             2440      2450   

>>XP_016885091 (OMIM: 300032,300448,300504,301040,309580  (2452 aa)
 initn: 15230 init1: 15230 opt: 15996  Z-score: 6482.4  bits: 1213.6 E(85289):    0
Smith-Waterman score: 15996; 100.0% identity (100.0% similar) in 2453 aa overlap (40-2492:1-2452)

      10        20        30        40        50        60         
pF1KE9 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE
                                     ::::::::::::::::::::::::::::::
XP_016                               MNQNTDKISGSGSNSDMMENSKEEGTSSSE
                                             10        20        30

      70        80        90       100       110       120         
pF1KE9 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KE9 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
       :::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRG-DGLHGIVSCTACGQQVNHFQKDSIYRH
              100       110       120        130       140         

     190       200       210       220       230       240         
pF1KE9 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
     150       160       170       180       190       200         

     250       260       270       280       290       300         
pF1KE9 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
     210       220       230       240       250       260         

     310       320       330       340       350       360         
pF1KE9 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
     270       280       290       300       310       320         

     370       380       390       400       410       420         
pF1KE9 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
     330       340       350       360       370       380         

     430       440       450       460       470       480         
pF1KE9 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
     390       400       410       420       430       440         

     490       500       510       520       530       540         
pF1KE9 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
     450       460       470       480       490       500         

     550       560       570       580       590       600         
pF1KE9 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
     510       520       530       540       550       560         

     610       620       630       640       650       660         
pF1KE9 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
     570       580       590       600       610       620         

     670       680       690       700       710       720         
pF1KE9 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
     630       640       650       660       670       680         

     730       740       750       760       770       780         
pF1KE9 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
     690       700       710       720       730       740         

     790       800       810       820       830       840         
pF1KE9 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
     750       760       770       780       790       800         

     850       860       870       880       890       900         
pF1KE9 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
     810       820       830       840       850       860         

     910       920       930       940       950       960         
pF1KE9 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
     870       880       890       900       910       920         

     970       980       990      1000      1010      1020         
pF1KE9 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
     930       940       950       960       970       980         

    1030      1040      1050      1060      1070      1080         
pF1KE9 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
     990      1000      1010      1020      1030      1040         

    1090      1100      1110      1120      1130      1140         
pF1KE9 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
    1050      1060      1070      1080      1090      1100         

    1150      1160      1170      1180      1190      1200         
pF1KE9 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
    1110      1120      1130      1140      1150      1160         

    1210      1220      1230      1240      1250      1260         
pF1KE9 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
    1170      1180      1190      1200      1210      1220         

    1270      1280      1290      1300      1310      1320         
pF1KE9 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
    1230      1240      1250      1260      1270      1280         

    1330      1340      1350      1360      1370      1380         
pF1KE9 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
    1290      1300      1310      1320      1330      1340         

    1390      1400      1410      1420      1430      1440         
pF1KE9 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
    1350      1360      1370      1380      1390      1400         

    1450      1460      1470      1480      1490      1500         
pF1KE9 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
    1410      1420      1430      1440      1450      1460         

    1510      1520      1530      1540      1550      1560         
pF1KE9 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
    1470      1480      1490      1500      1510      1520         

    1570      1580      1590      1600      1610      1620         
pF1KE9 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
    1530      1540      1550      1560      1570      1580         

    1630      1640      1650      1660      1670      1680         
pF1KE9 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
    1590      1600      1610      1620      1630      1640         

    1690      1700      1710      1720      1730      1740         
pF1KE9 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
    1650      1660      1670      1680      1690      1700         

    1750      1760      1770      1780      1790      1800         
pF1KE9 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
    1710      1720      1730      1740      1750      1760         

    1810      1820      1830      1840      1850      1860         
pF1KE9 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
    1770      1780      1790      1800      1810      1820         

    1870      1880      1890      1900      1910      1920         
pF1KE9 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
    1830      1840      1850      1860      1870      1880         

    1930      1940      1950      1960      1970      1980         
pF1KE9 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
    1890      1900      1910      1920      1930      1940         

    1990      2000      2010      2020      2030      2040         
pF1KE9 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
    1950      1960      1970      1980      1990      2000         

    2050      2060      2070      2080      2090      2100         
pF1KE9 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
    2010      2020      2030      2040      2050      2060         

    2110      2120      2130      2140      2150      2160         
pF1KE9 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
    2070      2080      2090      2100      2110      2120         

    2170      2180      2190      2200      2210      2220         
pF1KE9 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
    2130      2140      2150      2160      2170      2180         

    2230      2240      2250      2260      2270      2280         
pF1KE9 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
    2190      2200      2210      2220      2230      2240         

    2290      2300      2310      2320      2330      2340         
pF1KE9 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
    2250      2260      2270      2280      2290      2300         

    2350      2360      2370      2380      2390      2400         
pF1KE9 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
    2310      2320      2330      2340      2350      2360         

    2410      2420      2430      2440      2450      2460         
pF1KE9 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
    2370      2380      2390      2400      2410      2420         

    2470      2480      2490  
pF1KE9 PPLQRAPPPMRSKNPGPSQGKSM
       :::::::::::::::::::::::
XP_016 PPLQRAPPPMRSKNPGPSQGKSM
    2430      2440      2450  

>>XP_005262213 (OMIM: 300032,300448,300504,301040,309580  (2437 aa)
 initn: 15911 init1: 15911 opt: 15911  Z-score: 6448.1  bits: 1207.2 E(85289):    0
Smith-Waterman score: 15911; 100.0% identity (100.0% similar) in 2437 aa overlap (56-2492:1-2437)

          30        40        50        60        70        80     
pF1KE9 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI
                                     ::::::::::::::::::::::::::::::
XP_005                               MMENSKEEGTSSSEKSKSSGSSRSKRKPSI
                                             10        20        30

          90       100       110       120       130       140     
pF1KE9 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
               40        50        60        70        80        90

         150       160       170       180       190       200     
pF1KE9 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
              100       110       120       130       140       150

         210       220       230       240       250       260     
pF1KE9 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
              160       170       180       190       200       210

         270       280       290       300       310       320     
pF1KE9 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
              220       230       240       250       260       270

         330       340       350       360       370       380     
pF1KE9 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
              280       290       300       310       320       330

         390       400       410       420       430       440     
pF1KE9 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
              340       350       360       370       380       390

         450       460       470       480       490       500     
pF1KE9 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
              400       410       420       430       440       450

         510       520       530       540       550       560     
pF1KE9 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
              460       470       480       490       500       510

         570       580       590       600       610       620     
pF1KE9 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
              520       530       540       550       560       570

         630       640       650       660       670       680     
pF1KE9 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
              580       590       600       610       620       630

         690       700       710       720       730       740     
pF1KE9 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
              640       650       660       670       680       690

         750       760       770       780       790       800     
pF1KE9 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
              700       710       720       730       740       750

         810       820       830       840       850       860     
pF1KE9 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
              760       770       780       790       800       810

         870       880       890       900       910       920     
pF1KE9 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
              820       830       840       850       860       870

         930       940       950       960       970       980     
pF1KE9 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
              880       890       900       910       920       930

         990      1000      1010      1020      1030      1040     
pF1KE9 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
              940       950       960       970       980       990

        1050      1060      1070      1080      1090      1100     
pF1KE9 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
             1000      1010      1020      1030      1040      1050

        1110      1120      1130      1140      1150      1160     
pF1KE9 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
             1060      1070      1080      1090      1100      1110

        1170      1180      1190      1200      1210      1220     
pF1KE9 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
             1120      1130      1140      1150      1160      1170

        1230      1240      1250      1260      1270      1280     
pF1KE9 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
             1180      1190      1200      1210      1220      1230

        1290      1300      1310      1320      1330      1340     
pF1KE9 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
             1240      1250      1260      1270      1280      1290

        1350      1360      1370      1380      1390      1400     
pF1KE9 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
             1300      1310      1320      1330      1340      1350

        1410      1420      1430      1440      1450      1460     
pF1KE9 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
             1360      1370      1380      1390      1400      1410

        1470      1480      1490      1500      1510      1520     
pF1KE9 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
             1420      1430      1440      1450      1460      1470

        1530      1540      1550      1560      1570      1580     
pF1KE9 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
             1480      1490      1500      1510      1520      1530

        1590      1600      1610      1620      1630      1640     
pF1KE9 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
             1540      1550      1560      1570      1580      1590

        1650      1660      1670      1680      1690      1700     
pF1KE9 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
             1600      1610      1620      1630      1640      1650

        1710      1720      1730      1740      1750      1760     
pF1KE9 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
             1660      1670      1680      1690      1700      1710

        1770      1780      1790      1800      1810      1820     
pF1KE9 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
             1720      1730      1740      1750      1760      1770

        1830      1840      1850      1860      1870      1880     
pF1KE9 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
             1780      1790      1800      1810      1820      1830

        1890      1900      1910      1920      1930      1940     
pF1KE9 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
             1840      1850      1860      1870      1880      1890

        1950      1960      1970      1980      1990      2000     
pF1KE9 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
             1900      1910      1920      1930      1940      1950

        2010      2020      2030      2040      2050      2060     
pF1KE9 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
             1960      1970      1980      1990      2000      2010

        2070      2080      2090      2100      2110      2120     
pF1KE9 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
             2020      2030      2040      2050      2060      2070

        2130      2140      2150      2160      2170      2180     
pF1KE9 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
             2080      2090      2100      2110      2120      2130

        2190      2200      2210      2220      2230      2240     
pF1KE9 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
             2140      2150      2160      2170      2180      2190

        2250      2260      2270      2280      2290      2300     
pF1KE9 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
             2200      2210      2220      2230      2240      2250

        2310      2320      2330      2340      2350      2360     
pF1KE9 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
             2260      2270      2280      2290      2300      2310

        2370      2380      2390      2400      2410      2420     
pF1KE9 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
             2320      2330      2340      2350      2360      2370

        2430      2440      2450      2460      2470      2480     
pF1KE9 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
             2380      2390      2400      2410      2420      2430

        2490  
pF1KE9 PSQGKSM
       :::::::
XP_005 PSQGKSM
              

>>XP_016885092 (OMIM: 300032,300448,300504,301040,309580  (2436 aa)
 initn: 15230 init1: 15230 opt: 15893  Z-score: 6440.9  bits: 1205.9 E(85289):    0
Smith-Waterman score: 15893; 100.0% identity (100.0% similar) in 2437 aa overlap (56-2492:1-2436)

          30        40        50        60        70        80     
pF1KE9 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI
                                     ::::::::::::::::::::::::::::::
XP_016                               MMENSKEEGTSSSEKSKSSGSSRSKRKPSI
                                             10        20        30

          90       100       110       120       130       140     
pF1KE9 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
               40        50        60        70        80        90

         150       160       170       180       190       200     
pF1KE9 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSRSKMKTENLKKRG-DGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
              100        110       120       130       140         

         210       220       230       240       250       260     
pF1KE9 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
     150       160       170       180       190       200         

         270       280       290       300       310       320     
pF1KE9 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
     210       220       230       240       250       260         

         330       340       350       360       370       380     
pF1KE9 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
     270       280       290       300       310       320         

         390       400       410       420       430       440     
pF1KE9 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
     330       340       350       360       370       380         

         450       460       470       480       490       500     
pF1KE9 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
     390       400       410       420       430       440         

         510       520       530       540       550       560     
pF1KE9 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
     450       460       470       480       490       500         

         570       580       590       600       610       620     
pF1KE9 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
     510       520       530       540       550       560         

         630       640       650       660       670       680     
pF1KE9 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
     570       580       590       600       610       620         

         690       700       710       720       730       740     
pF1KE9 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
     630       640       650       660       670       680         

         750       760       770       780       790       800     
pF1KE9 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
     690       700       710       720       730       740         

         810       820       830       840       850       860     
pF1KE9 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
     750       760       770       780       790       800         

         870       880       890       900       910       920     
pF1KE9 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
     810       820       830       840       850       860         

         930       940       950       960       970       980     
pF1KE9 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
     870       880       890       900       910       920         

         990      1000      1010      1020      1030      1040     
pF1KE9 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
     930       940       950       960       970       980         

        1050      1060      1070      1080      1090      1100     
pF1KE9 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
     990      1000      1010      1020      1030      1040         

        1110      1120      1130      1140      1150      1160     
pF1KE9 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
    1050      1060      1070      1080      1090      1100         

        1170      1180      1190      1200      1210      1220     
pF1KE9 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
    1110      1120      1130      1140      1150      1160         

        1230      1240      1250      1260      1270      1280     
pF1KE9 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
    1170      1180      1190      1200      1210      1220         

        1290      1300      1310      1320      1330      1340     
pF1KE9 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
    1230      1240      1250      1260      1270      1280         

        1350      1360      1370      1380      1390      1400     
pF1KE9 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
    1290      1300      1310      1320      1330      1340         

        1410      1420      1430      1440      1450      1460     
pF1KE9 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
    1350      1360      1370      1380      1390      1400         

        1470      1480      1490      1500      1510      1520     
pF1KE9 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
    1410      1420      1430      1440      1450      1460         

        1530      1540      1550      1560      1570      1580     
pF1KE9 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
    1470      1480      1490      1500      1510      1520         

        1590      1600      1610      1620      1630      1640     
pF1KE9 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
    1530      1540      1550      1560      1570      1580         

        1650      1660      1670      1680      1690      1700     
pF1KE9 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
    1590      1600      1610      1620      1630      1640         

        1710      1720      1730      1740      1750      1760     
pF1KE9 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
    1650      1660      1670      1680      1690      1700         

        1770      1780      1790      1800      1810      1820     
pF1KE9 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
    1710      1720      1730      1740      1750      1760         

        1830      1840      1850      1860      1870      1880     
pF1KE9 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
    1770      1780      1790      1800      1810      1820         

        1890      1900      1910      1920      1930      1940     
pF1KE9 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
    1830      1840      1850      1860      1870      1880         

        1950      1960      1970      1980      1990      2000     
pF1KE9 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
    1890      1900      1910      1920      1930      1940         

        2010      2020      2030      2040      2050      2060     
pF1KE9 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
    1950      1960      1970      1980      1990      2000         

        2070      2080      2090      2100      2110      2120     
pF1KE9 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
    2010      2020      2030      2040      2050      2060         

        2130      2140      2150      2160      2170      2180     
pF1KE9 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
    2070      2080      2090      2100      2110      2120         

        2190      2200      2210      2220      2230      2240     
pF1KE9 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
    2130      2140      2150      2160      2170      2180         

        2250      2260      2270      2280      2290      2300     
pF1KE9 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
    2190      2200      2210      2220      2230      2240         

        2310      2320      2330      2340      2350      2360     
pF1KE9 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
    2250      2260      2270      2280      2290      2300         

        2370      2380      2390      2400      2410      2420     
pF1KE9 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
    2310      2320      2330      2340      2350      2360         

        2430      2440      2450      2460      2470      2480     
pF1KE9 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
    2370      2380      2390      2400      2410      2420         

        2490  
pF1KE9 PSQGKSM
       :::::::
XP_016 PSQGKSM
    2430      

>>NP_612114 (OMIM: 300032,300448,300504,301040,309580) t  (2454 aa)
 initn: 15991 init1: 15236 opt: 15259  Z-score: 6184.7  bits: 1158.5 E(85289):    0
Smith-Waterman score: 15919; 98.5% identity (98.5% similar) in 2492 aa overlap (1-2492:1-2454)

               10        20        30        40        50        60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
       :::                                      :::::::::::::::::::
NP_612 LPK--------------------------------------EDGLHGIVSCTACGQQVNH
                                                    130       140  

              190       200       210       220       230       240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
            150       160       170       180       190       200  

              250       260       270       280       290       300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
            210       220       230       240       250       260  

              310       320       330       340       350       360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
            270       280       290       300       310       320  

              370       380       390       400       410       420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
            330       340       350       360       370       380  

              430       440       450       460       470       480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
            390       400       410       420       430       440  

              490       500       510       520       530       540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
            450       460       470       480       490       500  

              550       560       570       580       590       600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
            510       520       530       540       550       560  

              610       620       630       640       650       660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
            570       580       590       600       610       620  

              670       680       690       700       710       720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
            630       640       650       660       670       680  

              730       740       750       760       770       780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
            690       700       710       720       730       740  

              790       800       810       820       830       840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
            750       760       770       780       790       800  

              850       860       870       880       890       900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
            810       820       830       840       850       860  

              910       920       930       940       950       960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
            870       880       890       900       910       920  

              970       980       990      1000      1010      1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
            930       940       950       960       970       980  

             1030      1040      1050      1060      1070      1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
            990      1000      1010      1020      1030      1040  

             1090      1100      1110      1120      1130      1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
           1050      1060      1070      1080      1090      1100  

             1150      1160      1170      1180      1190      1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
           1110      1120      1130      1140      1150      1160  

             1210      1220      1230      1240      1250      1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
           1170      1180      1190      1200      1210      1220  

             1270      1280      1290      1300      1310      1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
           1230      1240      1250      1260      1270      1280  

             1330      1340      1350      1360      1370      1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
           1290      1300      1310      1320      1330      1340  

             1390      1400      1410      1420      1430      1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
           1350      1360      1370      1380      1390      1400  

             1450      1460      1470      1480      1490      1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
           1410      1420      1430      1440      1450      1460  

             1510      1520      1530      1540      1550      1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
           1470      1480      1490      1500      1510      1520  

             1570      1580      1590      1600      1610      1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
           1530      1540      1550      1560      1570      1580  

             1630      1640      1650      1660      1670      1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
           1590      1600      1610      1620      1630      1640  

             1690      1700      1710      1720      1730      1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
           1650      1660      1670      1680      1690      1700  

             1750      1760      1770      1780      1790      1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
           1710      1720      1730      1740      1750      1760  

             1810      1820      1830      1840      1850      1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
           1770      1780      1790      1800      1810      1820  

             1870      1880      1890      1900      1910      1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
           1830      1840      1850      1860      1870      1880  

             1930      1940      1950      1960      1970      1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
           1890      1900      1910      1920      1930      1940  

             1990      2000      2010      2020      2030      2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
           1950      1960      1970      1980      1990      2000  

             2050      2060      2070      2080      2090      2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
           2010      2020      2030      2040      2050      2060  

             2110      2120      2130      2140      2150      2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
           2070      2080      2090      2100      2110      2120  

             2170      2180      2190      2200      2210      2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
           2130      2140      2150      2160      2170      2180  

             2230      2240      2250      2260      2270      2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
           2190      2200      2210      2220      2230      2240  

             2290      2300      2310      2320      2330      2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
           2250      2260      2270      2280      2290      2300  

             2350      2360      2370      2380      2390      2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
           2310      2320      2330      2340      2350      2360  

             2410      2420      2430      2440      2450      2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
           2370      2380      2390      2400      2410      2420  

             2470      2480      2490  
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
       ::::::::::::::::::::::::::::::::
NP_612 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
           2430      2440      2450    

>>XP_006724730 (OMIM: 300032,300448,300504,301040,309580  (2399 aa)
 initn: 15644 init1: 15236 opt: 15252  Z-score: 6182.0  bits: 1158.0 E(85289):    0
Smith-Waterman score: 15572; 98.4% identity (98.4% similar) in 2437 aa overlap (56-2492:1-2399)

          30        40        50        60        70        80     
pF1KE9 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI
                                     ::::::::::::::::::::::::::::::
XP_006                               MMENSKEEGTSSSEKSKSSGSSRSKRKPSI
                                             10        20        30

          90       100       110       120       130       140     
pF1KE9 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
       ::::::::::::::::::::::::::::::::::::::                      
XP_006 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPK----------------------
               40        50        60                              

         150       160       170       180       190       200     
pF1KE9 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----------------EDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
                       70        80        90       100       110  

         210       220       230       240       250       260     
pF1KE9 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
            120       130       140       150       160       170  

         270       280       290       300       310       320     
pF1KE9 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
            180       190       200       210       220       230  

         330       340       350       360       370       380     
pF1KE9 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
            240       250       260       270       280       290  

         390       400       410       420       430       440     
pF1KE9 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
            300       310       320       330       340       350  

         450       460       470       480       490       500     
pF1KE9 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
            360       370       380       390       400       410  

         510       520       530       540       550       560     
pF1KE9 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
            420       430       440       450       460       470  

         570       580       590       600       610       620     
pF1KE9 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
            480       490       500       510       520       530  

         630       640       650       660       670       680     
pF1KE9 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
            540       550       560       570       580       590  

         690       700       710       720       730       740     
pF1KE9 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
            600       610       620       630       640       650  

         750       760       770       780       790       800     
pF1KE9 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
            660       670       680       690       700       710  

         810       820       830       840       850       860     
pF1KE9 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
            720       730       740       750       760       770  

         870       880       890       900       910       920     
pF1KE9 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
            780       790       800       810       820       830  

         930       940       950       960       970       980     
pF1KE9 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
            840       850       860       870       880       890  

         990      1000      1010      1020      1030      1040     
pF1KE9 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
            900       910       920       930       940       950  

        1050      1060      1070      1080      1090      1100     
pF1KE9 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
            960       970       980       990      1000      1010  

        1110      1120      1130      1140      1150      1160     
pF1KE9 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
           1020      1030      1040      1050      1060      1070  

        1170      1180      1190      1200      1210      1220     
pF1KE9 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
           1080      1090      1100      1110      1120      1130  

        1230      1240      1250      1260      1270      1280     
pF1KE9 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
           1140      1150      1160      1170      1180      1190  

        1290      1300      1310      1320      1330      1340     
pF1KE9 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
           1200      1210      1220      1230      1240      1250  

        1350      1360      1370      1380      1390      1400     
pF1KE9 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
           1260      1270      1280      1290      1300      1310  

        1410      1420      1430      1440      1450      1460     
pF1KE9 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
           1320      1330      1340      1350      1360      1370  

        1470      1480      1490      1500      1510      1520     
pF1KE9 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
           1380      1390      1400      1410      1420      1430  

        1530      1540      1550      1560      1570      1580     
pF1KE9 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
           1440      1450      1460      1470      1480      1490  

        1590      1600      1610      1620      1630      1640     
pF1KE9 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
           1500      1510      1520      1530      1540      1550  

        1650      1660      1670      1680      1690      1700     
pF1KE9 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
           1560      1570      1580      1590      1600      1610  

        1710      1720      1730      1740      1750      1760     
pF1KE9 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
           1620      1630      1640      1650      1660      1670  

        1770      1780      1790      1800      1810      1820     
pF1KE9 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
           1680      1690      1700      1710      1720      1730  

        1830      1840      1850      1860      1870      1880     
pF1KE9 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
           1740      1750      1760      1770      1780      1790  

        1890      1900      1910      1920      1930      1940     
pF1KE9 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
           1800      1810      1820      1830      1840      1850  

        1950      1960      1970      1980      1990      2000     
pF1KE9 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
           1860      1870      1880      1890      1900      1910  

        2010      2020      2030      2040      2050      2060     
pF1KE9 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
           1920      1930      1940      1950      1960      1970  

        2070      2080      2090      2100      2110      2120     
pF1KE9 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
           1980      1990      2000      2010      2020      2030  

        2130      2140      2150      2160      2170      2180     
pF1KE9 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
           2040      2050      2060      2070      2080      2090  

        2190      2200      2210      2220      2230      2240     
pF1KE9 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
           2100      2110      2120      2130      2140      2150  

        2250      2260      2270      2280      2290      2300     
pF1KE9 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
           2160      2170      2180      2190      2200      2210  

        2310      2320      2330      2340      2350      2360     
pF1KE9 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
           2220      2230      2240      2250      2260      2270  

        2370      2380      2390      2400      2410      2420     
pF1KE9 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
           2280      2290      2300      2310      2320      2330  

        2430      2440      2450      2460      2470      2480     
pF1KE9 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
           2340      2350      2360      2370      2380      2390  

        2490  
pF1KE9 PSQGKSM
       :::::::
XP_006 PSQGKSM
              

>>XP_016885095 (OMIM: 300032,300448,300504,301040,309580  (2415 aa)
 initn: 15747 init1: 15236 opt: 15252  Z-score: 6181.9  bits: 1158.0 E(85289):    0
Smith-Waterman score: 15675; 98.5% identity (98.5% similar) in 2453 aa overlap (40-2492:1-2415)

      10        20        30        40        50        60         
pF1KE9 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE
                                     ::::::::::::::::::::::::::::::
XP_016                               MNQNTDKISGSGSNSDMMENSKEEGTSSSE
                                             10        20        30

      70        80        90       100       110       120         
pF1KE9 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPK------
               40        50        60        70        80          

     130       140       150       160       170       180         
pF1KE9 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
                                       ::::::::::::::::::::::::::::
XP_016 --------------------------------EDGLHGIVSCTACGQQVNHFQKDSIYRH
                                           90       100       110  

     190       200       210       220       230       240         
pF1KE9 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
            120       130       140       150       160       170  

     250       260       270       280       290       300         
pF1KE9 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
            180       190       200       210       220       230  

     310       320       330       340       350       360         
pF1KE9 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
            240       250       260       270       280       290  

     370       380       390       400       410       420         
pF1KE9 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
            300       310       320       330       340       350  

     430       440       450       460       470       480         
pF1KE9 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
            360       370       380       390       400       410  

     490       500       510       520       530       540         
pF1KE9 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
            420       430       440       450       460       470  

     550       560       570       580       590       600         
pF1KE9 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
            480       490       500       510       520       530  

     610       620       630       640       650       660         
pF1KE9 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
            540       550       560       570       580       590  

     670       680       690       700       710       720         
pF1KE9 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
            600       610       620       630       640       650  

     730       740       750       760       770       780         
pF1KE9 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
            660       670       680       690       700       710  

     790       800       810       820       830       840         
pF1KE9 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
            720       730       740       750       760       770  

     850       860       870       880       890       900         
pF1KE9 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
            780       790       800       810       820       830  

     910       920       930       940       950       960         
pF1KE9 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
            840       850       860       870       880       890  

     970       980       990      1000      1010      1020         
pF1KE9 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
            900       910       920       930       940       950  

    1030      1040      1050      1060      1070      1080         
pF1KE9 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
            960       970       980       990      1000      1010  

    1090      1100      1110      1120      1130      1140         
pF1KE9 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
           1020      1030      1040      1050      1060      1070  

    1150      1160      1170      1180      1190      1200         
pF1KE9 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
           1080      1090      1100      1110      1120      1130  

    1210      1220      1230      1240      1250      1260         
pF1KE9 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
           1140      1150      1160      1170      1180      1190  

    1270      1280      1290      1300      1310      1320         
pF1KE9 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
           1200      1210      1220      1230      1240      1250  

    1330      1340      1350      1360      1370      1380         
pF1KE9 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
           1260      1270      1280      1290      1300      1310  

    1390      1400      1410      1420      1430      1440         
pF1KE9 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
           1320      1330      1340      1350      1360      1370  

    1450      1460      1470      1480      1490      1500         
pF1KE9 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
           1380      1390      1400      1410      1420      1430  

    1510      1520      1530      1540      1550      1560         
pF1KE9 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
           1440      1450      1460      1470      1480      1490  

    1570      1580      1590      1600      1610      1620         
pF1KE9 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
           1500      1510      1520      1530      1540      1550  

    1630      1640      1650      1660      1670      1680         
pF1KE9 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
           1560      1570      1580      1590      1600      1610  

    1690      1700      1710      1720      1730      1740         
pF1KE9 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
           1620      1630      1640      1650      1660      1670  

    1750      1760      1770      1780      1790      1800         
pF1KE9 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
           1680      1690      1700      1710      1720      1730  

    1810      1820      1830      1840      1850      1860         
pF1KE9 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
           1740      1750      1760      1770      1780      1790  

    1870      1880      1890      1900      1910      1920         
pF1KE9 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
           1800      1810      1820      1830      1840      1850  

    1930      1940      1950      1960      1970      1980         
pF1KE9 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
           1860      1870      1880      1890      1900      1910  

    1990      2000      2010      2020      2030      2040         
pF1KE9 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
           1920      1930      1940      1950      1960      1970  

    2050      2060      2070      2080      2090      2100         
pF1KE9 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
           1980      1990      2000      2010      2020      2030  

    2110      2120      2130      2140      2150      2160         
pF1KE9 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
           2040      2050      2060      2070      2080      2090  

    2170      2180      2190      2200      2210      2220         
pF1KE9 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
           2100      2110      2120      2130      2140      2150  

    2230      2240      2250      2260      2270      2280         
pF1KE9 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
           2160      2170      2180      2190      2200      2210  

    2290      2300      2310      2320      2330      2340         
pF1KE9 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
           2220      2230      2240      2250      2260      2270  

    2350      2360      2370      2380      2390      2400         
pF1KE9 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
           2280      2290      2300      2310      2320      2330  

    2410      2420      2430      2440      2450      2460         
pF1KE9 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
           2340      2350      2360      2370      2380      2390  

    2470      2480      2490  
pF1KE9 PPLQRAPPPMRSKNPGPSQGKSM
       :::::::::::::::::::::::
XP_016 PPLQRAPPPMRSKNPGPSQGKSM
           2400      2410     

>>XP_006724729 (OMIM: 300032,300448,300504,301040,309580  (2453 aa)
 initn: 15231 init1: 15231 opt: 15251  Z-score: 6181.4  bits: 1157.9 E(85289):    0
Smith-Waterman score: 15911; 98.4% identity (98.4% similar) in 2492 aa overlap (1-2492:1-2453)

               10        20        30        40        50        60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
       :::                                       ::::::::::::::::::
XP_006 LPK---------------------------------------DGLHGIVSCTACGQQVNH
                                                     130       140 

              190       200       210       220       230       240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
             150       160       170       180       190       200 

              250       260       270       280       290       300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
             210       220       230       240       250       260 

              310       320       330       340       350       360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
             270       280       290       300       310       320 

              370       380       390       400       410       420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
             330       340       350       360       370       380 

              430       440       450       460       470       480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
             390       400       410       420       430       440 

              490       500       510       520       530       540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
             450       460       470       480       490       500 

              550       560       570       580       590       600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
             510       520       530       540       550       560 

              610       620       630       640       650       660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
             570       580       590       600       610       620 

              670       680       690       700       710       720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
             630       640       650       660       670       680 

              730       740       750       760       770       780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
             690       700       710       720       730       740 

              790       800       810       820       830       840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
             750       760       770       780       790       800 

              850       860       870       880       890       900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
             810       820       830       840       850       860 

              910       920       930       940       950       960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
             870       880       890       900       910       920 

              970       980       990      1000      1010      1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
             930       940       950       960       970       980 

             1030      1040      1050      1060      1070      1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
             990      1000      1010      1020      1030      1040 

             1090      1100      1110      1120      1130      1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
            1050      1060      1070      1080      1090      1100 

             1150      1160      1170      1180      1190      1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
            1110      1120      1130      1140      1150      1160 

             1210      1220      1230      1240      1250      1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
            1170      1180      1190      1200      1210      1220 

             1270      1280      1290      1300      1310      1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
            1230      1240      1250      1260      1270      1280 

             1330      1340      1350      1360      1370      1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
            1290      1300      1310      1320      1330      1340 

             1390      1400      1410      1420      1430      1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
            1350      1360      1370      1380      1390      1400 

             1450      1460      1470      1480      1490      1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
            1410      1420      1430      1440      1450      1460 

             1510      1520      1530      1540      1550      1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
            1470      1480      1490      1500      1510      1520 

             1570      1580      1590      1600      1610      1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
            1530      1540      1550      1560      1570      1580 

             1630      1640      1650      1660      1670      1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
            1590      1600      1610      1620      1630      1640 

             1690      1700      1710      1720      1730      1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
            1650      1660      1670      1680      1690      1700 

             1750      1760      1770      1780      1790      1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
            1710      1720      1730      1740      1750      1760 

             1810      1820      1830      1840      1850      1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
            1770      1780      1790      1800      1810      1820 

             1870      1880      1890      1900      1910      1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
            1830      1840      1850      1860      1870      1880 

             1930      1940      1950      1960      1970      1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
            1890      1900      1910      1920      1930      1940 

             1990      2000      2010      2020      2030      2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
            1950      1960      1970      1980      1990      2000 

             2050      2060      2070      2080      2090      2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
            2010      2020      2030      2040      2050      2060 

             2110      2120      2130      2140      2150      2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
            2070      2080      2090      2100      2110      2120 

             2170      2180      2190      2200      2210      2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
            2130      2140      2150      2160      2170      2180 

             2230      2240      2250      2260      2270      2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
            2190      2200      2210      2220      2230      2240 

             2290      2300      2310      2320      2330      2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
            2250      2260      2270      2280      2290      2300 

             2350      2360      2370      2380      2390      2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
            2310      2320      2330      2340      2350      2360 

             2410      2420      2430      2440      2450      2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
            2370      2380      2390      2400      2410      2420 

             2470      2480      2490  
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
       ::::::::::::::::::::::::::::::::
XP_006 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
            2430      2440      2450   




2492 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:11:03 2016 done: Sat Nov  5 19:11:07 2016
 Total Scan time: 23.930 Total Display time:  2.500

Function used was FASTA [36.3.4 Apr, 2011]
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