Result of FASTA (omim) for pF1KB3508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3508, 328 aa
  1>>>pF1KB3508 328 - 328 aa - 328 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4685+/-0.000443; mu= 14.7843+/- 0.028
 mean_var=66.3142+/-13.209, 0's: 0 Z-trim(110.7): 73  B-trim: 111 in 1/49
 Lambda= 0.157496
 statistics sampled from 19046 (19120) to 19046 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.597), E-opt: 0.2 (0.224), width:  16
 Scan time:  6.370

The best scores are:                                      opt bits E(85289)
NP_064563 (OMIM: 604642) carbonic anhydrase-relate ( 328) 2216 512.7 4.3e-145
NP_001076003 (OMIM: 604642) carbonic anhydrase-rel ( 328) 2216 512.7 4.3e-145
NP_001076002 (OMIM: 604642) carbonic anhydrase-rel ( 328) 2216 512.7 4.3e-145
XP_016880367 (OMIM: 604642) PREDICTED: carbonic an ( 231) 1539 358.8 6.5e-99
NP_001208 (OMIM: 604644) carbonic anhydrase-relate ( 328) 1223 287.0 3.6e-77
NP_005173 (OMIM: 114770) carbonic anhydrase 7 isof ( 264)  523 127.9 2.3e-29
NP_000058 (OMIM: 259730,611492) carbonic anhydrase ( 260)  498 122.3 1.1e-27
NP_940986 (OMIM: 611436) carbonic anhydrase 13 [Ho ( 262)  494 121.3 2.2e-27
XP_016884736 (OMIM: 300230) PREDICTED: carbonic an ( 278)  489 120.2   5e-27
NP_001730 (OMIM: 114761,615751) carbonic anhydrase ( 305)  484 119.1 1.2e-26
XP_005274499 (OMIM: 300230) PREDICTED: carbonic an ( 317)  484 119.1 1.2e-26
NP_009151 (OMIM: 300230) carbonic anhydrase 5B, mi ( 317)  484 119.1 1.2e-26
NP_005172 (OMIM: 114750) carbonic anhydrase 3 [Hom ( 260)  469 115.7 1.1e-25
NP_001308766 (OMIM: 114815,613227) carbonic anhydr ( 290)  468 115.5 1.4e-25
NP_004047 (OMIM: 114815,613227) carbonic anhydrase ( 290)  468 115.5 1.4e-25
NP_001122302 (OMIM: 114800) carbonic anhydrase 1 i ( 261)  464 114.5 2.4e-25
NP_001158302 (OMIM: 114800) carbonic anhydrase 1 i ( 261)  464 114.5 2.4e-25
NP_001122303 (OMIM: 114800) carbonic anhydrase 1 i ( 261)  464 114.5 2.4e-25
NP_001729 (OMIM: 114800) carbonic anhydrase 1 isof ( 261)  464 114.5 2.4e-25
NP_001122301 (OMIM: 114800) carbonic anhydrase 1 i ( 261)  464 114.5 2.4e-25
NP_001014435 (OMIM: 114770) carbonic anhydrase 7 i ( 208)  450 111.3 1.8e-24
XP_011521614 (OMIM: 114770) PREDICTED: carbonic an ( 208)  450 111.3 1.8e-24
XP_005256193 (OMIM: 114770) PREDICTED: carbonic an ( 208)  450 111.3 1.8e-24
XP_011521613 (OMIM: 114770) PREDICTED: carbonic an ( 242)  445 110.2 4.5e-24
NP_996808 (OMIM: 143860,603263) carbonic anhydrase ( 343)  437 108.5 2.2e-23
NP_001209 (OMIM: 143860,603263) carbonic anhydrase ( 354)  436 108.2 2.6e-23
XP_016879135 (OMIM: 114761,615751) PREDICTED: carb ( 314)  420 104.6 2.9e-22
XP_016884737 (OMIM: 300230) PREDICTED: carbonic an ( 248)  417 103.8 3.8e-22
NP_001308767 (OMIM: 114815,613227) carbonic anhydr ( 263)  411 102.5   1e-21
XP_006711322 (OMIM: 604832) PREDICTED: carbonic an ( 318)  411 102.5 1.2e-21
XP_016869307 (OMIM: 114815,613227) PREDICTED: carb ( 206)  407 101.5 1.6e-21
XP_005245117 (OMIM: 604832) PREDICTED: carbonic an ( 319)  409 102.1 1.7e-21
XP_005245116 (OMIM: 604832) PREDICTED: carbonic an ( 336)  409 102.1 1.7e-21
NP_036245 (OMIM: 604832) carbonic anhydrase 14 pre ( 337)  409 102.1 1.8e-21
NP_001278896 (OMIM: 114800) carbonic anhydrase 1 i ( 195)  402 100.4 3.3e-21
NP_001257429 (OMIM: 114780) carbonic anhydrase 6 i ( 313)  399 99.8 7.9e-21
XP_011540385 (OMIM: 114780) PREDICTED: carbonic an ( 294)  379 95.2 1.8e-19
NP_001206 (OMIM: 114780) carbonic anhydrase 6 isof ( 308)  379 95.3 1.8e-19
XP_011540386 (OMIM: 114780) PREDICTED: carbonic an ( 324)  379 95.3 1.9e-19
NP_001280571 (OMIM: 143860,603263) carbonic anhydr ( 283)  378 95.0   2e-19
NP_001207 (OMIM: 603179) carbonic anhydrase 9 prec ( 459)  372 93.7 7.8e-19
XP_016856382 (OMIM: 604832) PREDICTED: carbonic an ( 263)  361 91.1 2.7e-18
XP_006711324 (OMIM: 604832) PREDICTED: carbonic an ( 281)  361 91.1 2.9e-18
XP_011507681 (OMIM: 604832) PREDICTED: carbonic an ( 323)  360 90.9 3.8e-18
XP_005265410 (OMIM: 176886) PREDICTED: receptor-ty (1416)  355 90.1   3e-17
NP_002832 (OMIM: 176886) receptor-type tyrosine-pr (1445)  355 90.1   3e-17
NP_000708 (OMIM: 114760,600852) carbonic anhydrase ( 312)  346 87.8 3.3e-17
XP_016862453 (OMIM: 176886) PREDICTED: receptor-ty (1329)  329 84.2 1.7e-15
XP_011521611 (OMIM: 114761,615751) PREDICTED: carb ( 376)  321 82.1   2e-15
XP_011521612 (OMIM: 114761,615751) PREDICTED: carb ( 222)  311 79.7 6.2e-15


>>NP_064563 (OMIM: 604642) carbonic anhydrase-related pr  (328 aa)
 initn: 2216 init1: 2216 opt: 2216  Z-score: 2725.8  bits: 512.7 E(85289): 4.3e-145
Smith-Waterman score: 2216; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328)

               10        20        30        40        50        60
pF1KB3 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN
              250       260       270       280       290       300

              310       320        
pF1KB3 INFSLQGKDCPNNRAQKLQYRVNEWLLK
       ::::::::::::::::::::::::::::
NP_064 INFSLQGKDCPNNRAQKLQYRVNEWLLK
              310       320        

>>NP_001076003 (OMIM: 604642) carbonic anhydrase-related  (328 aa)
 initn: 2216 init1: 2216 opt: 2216  Z-score: 2725.8  bits: 512.7 E(85289): 4.3e-145
Smith-Waterman score: 2216; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328)

               10        20        30        40        50        60
pF1KB3 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN
              250       260       270       280       290       300

              310       320        
pF1KB3 INFSLQGKDCPNNRAQKLQYRVNEWLLK
       ::::::::::::::::::::::::::::
NP_001 INFSLQGKDCPNNRAQKLQYRVNEWLLK
              310       320        

>>NP_001076002 (OMIM: 604642) carbonic anhydrase-related  (328 aa)
 initn: 2216 init1: 2216 opt: 2216  Z-score: 2725.8  bits: 512.7 E(85289): 4.3e-145
Smith-Waterman score: 2216; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328)

               10        20        30        40        50        60
pF1KB3 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN
              250       260       270       280       290       300

              310       320        
pF1KB3 INFSLQGKDCPNNRAQKLQYRVNEWLLK
       ::::::::::::::::::::::::::::
NP_001 INFSLQGKDCPNNRAQKLQYRVNEWLLK
              310       320        

>>XP_016880367 (OMIM: 604642) PREDICTED: carbonic anhydr  (231 aa)
 initn: 1539 init1: 1539 opt: 1539  Z-score: 1896.8  bits: 358.8 E(85289): 6.5e-99
Smith-Waterman score: 1539; 100.0% identity (100.0% similar) in 231 aa overlap (98-328:1-231)

        70        80        90       100       110       120       
pF1KB3 PVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHR
                                     ::::::::::::::::::::::::::::::
XP_016                               MYNTGRHVSLRLDKEHLVNISGGPMTYSHR
                                             10        20        30

       130       140       150       160       170       180       
pF1KB3 LEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIK
               40        50        60        70        80        90

       190       200       210       220       230       240       
pF1KB3 VSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYET
              100       110       120       130       140       150

       250       260       270       280       290       300       
pF1KB3 ASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQG
              160       170       180       190       200       210

       310       320        
pF1KB3 KDCPNNRAQKLQYRVNEWLLK
       :::::::::::::::::::::
XP_016 KDCPNNRAQKLQYRVNEWLLK
              220       230 

>>NP_001208 (OMIM: 604644) carbonic anhydrase-related pr  (328 aa)
 initn: 1210 init1: 1210 opt: 1223  Z-score: 1506.4  bits: 287.0 E(85289): 3.6e-77
Smith-Waterman score: 1223; 58.9% identity (84.0% similar) in 287 aa overlap (30-314:32-318)

                10        20        30        40        50         
pF1KB3  MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNL
                                     : ::.::. .::.::: : ::::::.::.:
NP_001 GAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSL
              10        20        30        40        50        60 

      60        70        80        90       100       110         
pF1KB3 CSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISG
       :.::::::::..: .....:::: :::..:::.:. ::.::::::::.    . .::.::
NP_001 CAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSG
              70        80        90       100       110       120 

     120       130       140       150       160       170         
pF1KB3 GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGL
       ::. ::::: :.:: ::..:. :::: .: :.::.::::::.:.::: : . :...::::
NP_001 GPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGL
             130       140       150       160       170       180 

     180       190       200       210       220       230         
pF1KB3 VVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSM
       ...:.:..:...:::::.:.:::::::::.::::::.:: :..: :.::. .::::.::.
NP_001 AILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSL
             190       200       210       220       230       240 

     240       250       260       270       280       290         
pF1KB3 TIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRT
       . ::: ::..::.... . :: .::::::::::: ::::: :.: : ::.::: .: .: 
NP_001 STPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRG
             250       260       270       280       290       300 

     300       310         320        
pF1KB3 NINFSLQGKDC--PNNRAQKLQYRVNEWLLK
       : .     . :  :: :              
NP_001 NRDPRHPERRCRGPNYRLHVDGVPHGR    
             310       320            

>>NP_005173 (OMIM: 114770) carbonic anhydrase 7 isoform   (264 aa)
 initn: 470 init1: 284 opt: 523  Z-score: 648.3  bits: 127.9 E(85289): 2.3e-29
Smith-Waterman score: 526; 31.1% identity (68.9% similar) in 273 aa overlap (29-300:4-261)

               10        20        30        40        50        60
pF1KB3 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLC
                                   :.::   ..  .:     :: :   .. . . 
NP_005                          MTGHHGWGYGQD--DG-----PSHW---HKLYPIA
                                        10                  20     

               70        80        90       100        110         
pF1KB3 SVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRL-DKEHLVNISG
       . : ::::.:: .:. ...: : ::...  .  .: .. :.:. :.. . :..  . ..:
NP_005 Q-GDRQSPINIISSQAVYSPSLQPLELSYEA-CMSLSITNNGHSVQVDFNDSDDRTVVTG
           30        40        50         60        70        80   

     120       130       140       150       160       170         
pF1KB3 GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGL
       ::.   .::.....:.:.. . :::: ..:..: .:..:.:.: . :..  :::..:.::
NP_005 GPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGL
            90       100       110       120       130       140   

     180       190       200       210       220       230         
pF1KB3 VVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSM
       .::..:....:  .: .::.   :..  . .:.    .. .: . : : .  . :: ::.
NP_005 AVVGVFLETGDE-HPSMNRLT--DALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSL
           150        160         170       180       190       200

     240       250       260       270       280       290         
pF1KB3 TIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRT
       : ::  :...::.. .:. :.. :: ..: :  .. ..  . : .:::: :::..: ...
NP_005 TTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKA
              210       220       230       240       250       260

     300       310       320        
pF1KB3 NINFSLQGKDCPNNRAQKLQYRVNEWLLK
       .                            
NP_005 SFRA                         
                                    

>>NP_000058 (OMIM: 259730,611492) carbonic anhydrase 2 i  (260 aa)
 initn: 423 init1: 204 opt: 498  Z-score: 617.7  bits: 122.3 E(85289): 1.1e-27
Smith-Waterman score: 498; 33.5% identity (71.5% similar) in 239 aa overlap (63-300:25-258)

             40        50        60        70        80        90  
pF1KB3 WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGR
                                     :.:::::.:.:    .:: : :: ..   .
NP_000       MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYD-Q
                     10        20        30        40        50    

            100       110        120       130       140       150 
pF1KB3 KVSGTMYNTGRHVSLRLD-KEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQA
        .:  . :.:.  ....: ..  . ..:::.  ..:: ....:.:: :.::::: .. . 
NP_000 ATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKK
            60        70        80        90       100       110   

             160       170       180       190       200       210 
pF1KB3 FSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYK
       ...:..:.:.: . : .  .:...:.::.:..::.::. :..: :....  :..  :  :
NP_000 YAAELHLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVG-SAKPGLQKVV--DVLDSIKTK
           120        130       140       150        160           

             220       230       240       250       260       270 
pF1KB3 NDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLS
       . .  . ... . : ::. .. :: ::.: ::  : ..::....:. ..  :. ..: :.
NP_000 GKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLN
     170       180       190       200       210       220         

             280       290       300       310       320        
pF1KB3 QNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK
        :  ..    : ::.::.:::.:: :...                            
NP_000 FNGEGEPEELMVDNWRPAQPLKNRQIKASFK                          
     230       240       250       260                          

>>NP_940986 (OMIM: 611436) carbonic anhydrase 13 [Homo s  (262 aa)
 initn: 450 init1: 290 opt: 494  Z-score: 612.7  bits: 121.3 E(85289): 2.2e-27
Smith-Waterman score: 494; 31.1% identity (70.5% similar) in 241 aa overlap (63-302:26-262)

             40        50        60        70        80        90  
pF1KB3 WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGR
                                     : .:::..:.:... .:  : :: :.    
NP_940      MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPS
                    10        20        30        40        50     

            100       110        120       130       140       150 
pF1KB3 KVSGTMYNTGRHVSLRLDK-EHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQA
       ...  . :.:.  .. .:  :.   . :::.: :.::....::.:: :..::::...: .
NP_940 SAK-IISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVS
           60        70        80        90       100       110    

             160       170       180       190       200       210 
pF1KB3 FSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYK
       ...:....:.: . : . .:::. :.::.:...:.....  :  :...   ::.  :  :
NP_940 YAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEP-NSQLQKIT--DTLDSIKEK
          120       130       140       150        160         170 

             220       230       240       250       260       270 
pF1KB3 NDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLS
       .    . ....  : : . .. :: ::.:.::  :...::....:. :. .:. ..: : 
NP_940 GKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLL
             180       190       200       210       220       230 

             280       290       300       310       320        
pF1KB3 QNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK
        .  ..    . .: :: :::..: .:....                          
NP_940 CTAEGEAAAFLVSNHRPPQPLKGRKVRASFH                          
             240       250       260                            

>>XP_016884736 (OMIM: 300230) PREDICTED: carbonic anhydr  (278 aa)
 initn: 446 init1: 265 opt: 489  Z-score: 606.2  bits: 120.2 E(85289): 5e-27
Smith-Waterman score: 489; 31.8% identity (63.9% similar) in 277 aa overlap (40-311:4-271)

      10        20        30        40        50        60         
pF1KB3 LLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPV
                                     ::. : :  .:  :.    :   : ::::.
XP_016                            MLYQGQ-VGVHPLWESVD----LVPGGDRQSPI
                                           10            20        

      70        80        90       100        110       120        
pF1KB3 NIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRL-DKEHLVNISGGPMTYSHRL
       ::.    ..:: : :: :.     .   ..:.:    ... :.     :.:::. ...::
XP_016 NIRWRDSVYDPGLKPLTISYDP-ATCLHVWNNGYSFLVEFEDSTDKSVIKGGPLEHNYRL
       30        40        50         60        70        80       

      130       140       150       160       170       180        
pF1KB3 EEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKV
       .....:.:. :. :::: .... : .:..:.:.:   . :  .::   :::.:...:.:.
XP_016 KQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVFLKL
        90       100       110       120       130       140       

      190       200       210       220       230       240        
pF1KB3 SDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETA
       . . .  :....  ::.  : .:.    . ...   :.:   .. ::.::.: ::  :..
XP_016 G-KHHKELQKLV--DTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLSESV
        150         160       170       180       190       200    

      250       260       270       280       290       300        
pF1KB3 SWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNIN----FS
       .::: ..:: . . :....: :  .. ..    : :::::.::: :: .:...     ..
XP_016 TWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDYVLN
          210       220       230       240       250       260    

          310       320        
pF1KB3 LQGKDCPNNRAQKLQYRVNEWLLK
       .:.:  :                 
XP_016 VQAKPKPATSQATP          
          270                  

>>NP_001730 (OMIM: 114761,615751) carbonic anhydrase 5A,  (305 aa)
 initn: 440 init1: 268 opt: 484  Z-score: 599.4  bits: 119.1 E(85289): 1.2e-26
Smith-Waterman score: 484; 32.3% identity (66.5% similar) in 248 aa overlap (63-307:61-302)

             40        50        60        70        80        90  
pF1KB3 WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGR
                                     : ::::.::.    ..:: : :::..    
NP_001 GRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVS---Y
               40        50        60        70        80          

              100       110        120       130       140         
pF1KB3 KVSGTMY--NTGRHVSLRLDKEHLVN-ISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNG
       .... .:  :::   ....:    .. :::::.   .::.....:.:. .  :::: ..:
NP_001 EAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDG
        90       100       110       120       130       140       

     150       160       170       180       190       200         
pF1KB3 QAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRIT
       .:. .:..:.:.:   : :  ::. . :::.:...:.:.. . .  :.:..  : . .: 
NP_001 HAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLG-AHHQTLQRLV--DILPEIK
       150       160       170       180        190         200    

     210       220       230       240       250       260         
pF1KB3 YKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRL
       .:.    .. ..   : :   .. :: ::.: ::  :...:::...:: ..  :. ..: 
NP_001 HKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRT
          210       220       230       240       250       260    

     270       280       290       300       310       320        
pF1KB3 LSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK
       :  .  ..    : .:.::.::: :: . .... . .:                     
NP_001 LLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS                  
          270       280       290       300                       




328 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:10:59 2016 done: Sat Nov  5 12:11:00 2016
 Total Scan time:  6.370 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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