Result of FASTA (omim) for pF1KB6014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6014, 698 aa
  1>>>pF1KB6014 698 - 698 aa - 698 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8349+/-0.000304; mu= 18.5172+/- 0.019
 mean_var=86.1692+/-17.431, 0's: 0 Z-trim(119.1): 27  B-trim: 0 in 0/54
 Lambda= 0.138165
 statistics sampled from 32655 (32683) to 32655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.383), width:  16
 Scan time: 12.920

The best scores are:                                      opt bits E(85289)
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698) 4775 961.6       0
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747) 1609 330.5 1.4e-89
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604) 1587 326.1 2.5e-88
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402)  228 55.1 6.2e-07
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437)  228 55.1 6.6e-07
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440)  228 55.1 6.7e-07
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445)  228 55.1 6.7e-07
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488)  228 55.2 7.3e-07
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492)  228 55.2 7.3e-07
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508)  207 51.0 1.4e-05
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324)  200 49.5 2.5e-05
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432)  200 49.5 3.2e-05
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519)  198 49.2 4.8e-05
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505)  179 45.4 0.00065
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229)  171 43.6   0.001
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231)  171 43.6   0.001
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747)  174 44.5  0.0018
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454)  171 43.8  0.0018
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C  ( 793)  174 44.5  0.0019
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525)  161 41.8  0.0081


>>NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 precurso  (698 aa)
 initn: 4775 init1: 4775 opt: 4775  Z-score: 5140.3  bits: 961.6 E(85289):    0
Smith-Waterman score: 4775; 100.0% identity (100.0% similar) in 698 aa overlap (1-698:1-698)

               10        20        30        40        50        60
pF1KB6 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 DAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 DAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 DCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 EGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 ALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLPLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 EKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVTVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 AKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGCQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 AKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGCQG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 SRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKECG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 SRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKECG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 EHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPACH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPACH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 EEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPEVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPEVS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB6 HGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFSSLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 HGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFSSLD
              610       620       630       640       650       660

              670       680       690        
pF1KB6 MSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV
       ::::::::::::::::::::::::::::::::::::::
NP_859 MSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV
              670       680       690        

>>NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isoform   (747 aa)
 initn: 1645 init1: 554 opt: 1609  Z-score: 1729.3  bits: 330.5 E(85289): 1.4e-89
Smith-Waterman score: 1617; 41.5% identity (67.6% similar) in 620 aa overlap (25-629:8-613)

               10        20        30        40        50          
pF1KB6 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAAR--LYRA
                               : ::     : ::.::    . :::..: :  :: .
NP_002                  MRRCNSGSGPP-----PSLLLLLLWLLAVPGANAAPRSALY-S
                                10             20        30        

       60        70        80        90       100       110        
pF1KB6 GEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVA
         : . .:.. .::::. .: .:: :.:..:::::::..::::.::: ::. :  :. .:
NP_002 PSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA
        40        50        60        70        80        90       

      120       130       140       150       160       170        
pF1KB6 ALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQN
       :::: :: :.:::.:..:  .:: :.::::::.  .:  :     ...:.:. .:: :..
NP_002 ALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN-GSGAVFPVAGADVQTLRERLIDALES
       100       110       120       130        140       150      

      180       190       200       210       220       230        
pF1KB6 HTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVV
       : . . ::::: :.: .  .. ...   . .:.:..::...::::::: :::  .....:
NP_002 HHD-TWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAV
         160       170       180       190       200       210     

      240       250       260       270       280       290        
pF1KB6 TRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLP
        :.:. .   ..:.::.. :::::.. ::: . . :.   :.:...::. :  . ...  
NP_002 RRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQ
         220       230       240       250       260       270     

      300       310       320       330       340       350        
pF1KB6 LPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVT
           :   ..   .::.  :.::.: .::::.:::.::.:..    : : .: .:: ::.
NP_002 TTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVA
         280       290       300       310       320       330     

      360       370       380       390       400       410        
pF1KB6 VLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGC
       :::: ::::: :...:. ..:::     ..:::.     ...  :  :  :.....:.::
NP_002 VLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDD--RKEGAVLAKKVNWIGC
         340       350       360       370         380       390   

      420       430       440       450       460       470        
pF1KB6 QGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKE
       :::. ..::.::::: ::: :::.:. .   .  .      . :: ..: ::: ::::..
NP_002 QGSEPHFRGFPCSLWVLFHFLTVQAARQ--NVDHSQEAAKAKEVLPAIRGYVHYFFGCRD
           400       410       420         430       440       450 

      480       490       500       510       520       530        
pF1KB6 CGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPA
       :. :::.::  ::  : .:. :.::::..:: ::.::::  ::::.:::.:::  .:: :
NP_002 CASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSA
             460       470       480       490       500       510 

      540       550       560       570              580       590 
pF1KB6 CHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSA-------DQGDSSEGGTLARGEEE-
       ::.:   .  ::   .:.::: :.. .:..  . :       :  . . .  :: :  : 
NP_002 CHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALEL
             520       530       540       550       560       570 

                   600       610       620       630       640     
pF1KB6 EKR---LTP--PEVSHGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEV
       :.:   : :  ::. ..  .:    :  : ::. . : .:: .:                
NP_002 ESRNSTLDPGKPEMMKSPTNTTPHVP--AEGPEASRPPKLHPGLRAAPGQEPPEHMAELQ
             580       590         600       610       620         

         650       660       670       680       690               
pF1KB6 GGAAPFLGVDFSSLDMSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV       
                                                                   
NP_002 RNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEAR
     630       640       650       660       670       680         

>>NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 isofo  (604 aa)
 initn: 1531 init1: 554 opt: 1587  Z-score: 1706.9  bits: 326.1 E(85289): 2.5e-88
Smith-Waterman score: 1596; 41.1% identity (68.7% similar) in 603 aa overlap (25-624:8-588)

               10        20        30        40        50          
pF1KB6 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAAR--LYRA
                               : ::     : ::.::    . :::..: :  :: .
NP_001                  MRRCNSGSGPP-----PSLLLLLLWLLAVPGANAAPRSALY-S
                                10             20        30        

       60        70        80        90       100       110        
pF1KB6 GEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVA
         : . .:.. .::::. .: .:: :.:..:::::::..::::.::: ::. :  :. .:
NP_001 PSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA
        40        50        60        70        80        90       

      120       130       140       150       160       170        
pF1KB6 ALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQN
       :::: :: :.:::.:..:  .:: :.::::::.  .:  :     ...:.:. .:: :..
NP_001 ALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN-GSGAVFPVAGADVQTLRERLIDALES
       100       110       120       130        140       150      

      180       190       200       210       220       230        
pF1KB6 HTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVV
       : . . ::::: :.: .  .. ...   . .:.:..::...::::::: :::  .....:
NP_001 HHD-TWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAV
         160       170       180       190       200       210     

      240       250       260       270       280       290        
pF1KB6 TRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLP
        :.:. .   ..:.::.. :::::.. ::: . . :.   :.:...::. :  . ...  
NP_001 RRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQ
         220       230       240       250       260       270     

      300       310       320       330       340       350        
pF1KB6 LPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVT
           :   ..   .::.  :.::.: .::::.:::.::.:..    : : .: .:: ::.
NP_001 TTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVA
         280       290       300       310       320       330     

      360       370       380       390       400       410        
pF1KB6 VLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGC
       :::: ::::: :...:. ..:::     ..:::.     ...  :  :  :.....:.::
NP_001 VLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDD--RKEGAVLAKKVNWIGC
         340       350       360       370         380       390   

      420       430       440       450       460       470        
pF1KB6 QGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKE
       :::. ..::.::::: ::: :::.:. .   .  .      . :: ..: ::: ::::..
NP_001 QGSEPHFRGFPCSLWVLFHFLTVQAARQ--NVDHSQEAAKAKEVLPAIRGYVHYFFGCRD
           400       410       420         430       440       450 

      480       490       500       510       520       530        
pF1KB6 CGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPA
       :. :::.::  ::  : .:. :.::::..:: ::.::::  ::::.:::.:::  .:: :
NP_001 CASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSA
             460       470       480       490       500       510 

      540       550       560       570       580       590        
pF1KB6 CHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPE
       ::.:   .  ::   .:.::: :.. .:..  . :       .:. :: .. ..  . ::
NP_001 CHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPA-------AGSAAR-RDVQNVAAAPE
             520       530       540              550        560   

      600       610        620       630       640       650       
pF1KB6 VSHGDRDTQSVRPPGALGP-RPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFS
       .. :  . .:    ..: : .: . .:                                 
NP_001 LAMGALELESRN--STLDPGKPEMMKSPTNTTPHVPAEGPELI                 
           570         580       590       600                     

>>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi  (402 aa)
 initn: 131 init1: 106 opt: 228  Z-score: 245.5  bits: 55.1 E(85289): 6.2e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:20-168)

           30        40        50        60        70        80    
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
                                     :: ...:.. .  :.  :  . .:.. :::
XP_011            MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
                          10        20        30         40        

           90       100       110       120       130       140    
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
       .::. :::::   .: :.  :  ..:   ...:.:.:   .:....  .: .. .::.. 
XP_011 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
       50        60        70           80          90       100   

             150       160        170       180       190       200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
       :   :   ...  :.. ..  :  : ..:: . : : ... :       : :  . .::.
XP_011 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
           110       120       130       140       150       160   

              210       220       230       240       250       260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
        : :.                                                       
XP_011 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
           170       180       190       200       210       220   

>--
 initn: 153 init1: 104 opt: 186  Z-score: 200.2  bits: 46.7 E(85289): 0.00021
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:176-244)

         50        60        70        80        90       100      
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
                                     .:  .:.:.::. ::::: .  : : : :.
XP_011 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
         150       160       170       180       190       200     

        110        120       130       140       150       160     
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
       .:.. ... ...::.:     ::..   : :. .::.. :.                   
XP_011 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
         210       220         230       240       250       260   

         170       180       190       200       210       220     
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
                                                                   
XP_011 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
           270       280       290       300       310       320   

>>NP_001269636 (OMIM: 611099) protein disulfide-isomeras  (437 aa)
 initn: 131 init1: 106 opt: 228  Z-score: 244.9  bits: 55.1 E(85289): 6.6e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:17-165)

           30        40        50        60        70        80    
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
                                     :: ...:.. .  :.  :  . .:.. :::
NP_001               MILGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
                             10        20        30         40     

           90       100       110       120       130       140    
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
       .::. :::::   .: :.  :  ..:   ...:.:.:   .:....  .: .. .::.. 
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
          50        60        70           80          90       100

             150       160        170       180       190       200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
       :   :   ...  :.. ..  :  : ..:: . : : ... :       : :  . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
              110       120       130       140       150       160

              210       220       230       240       250       260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
        : :.                                                       
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
              170       180       190       200       210       220

>--
 initn: 157 init1: 104 opt: 186  Z-score: 199.7  bits: 46.7 E(85289): 0.00022
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:173-241)

         50        60        70        80        90       100      
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
                                     .:  .:.:.::. ::::: .  : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
            150       160       170       180       190       200  

        110        120       130       140       150       160     
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
       .:.. ... ...::.:     ::..   : :. .::.. :.                   
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
            210       220         230       240       250       260

         170       180       190       200       210       220     
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
                                                                   
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
              270       280       290       300       310       320

>>NP_005733 (OMIM: 611099) protein disulfide-isomerase A  (440 aa)
 initn: 131 init1: 106 opt: 228  Z-score: 244.9  bits: 55.1 E(85289): 6.7e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:20-168)

           30        40        50        60        70        80    
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
                                     :: ...:.. .  :.  :  . .:.. :::
NP_005            MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
                          10        20        30         40        

           90       100       110       120       130       140    
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
       .::. :::::   .: :.  :  ..:   ...:.:.:   .:....  .: .. .::.. 
NP_005 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
       50        60        70           80          90       100   

             150       160        170       180       190       200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
       :   :   ...  :.. ..  :  : ..:: . : : ... :       : :  . .::.
NP_005 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
           110       120       130       140       150       160   

              210       220       230       240       250       260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
        : :.                                                       
NP_005 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
           170       180       190       200       210       220   

>--
 initn: 157 init1: 104 opt: 186  Z-score: 199.6  bits: 46.8 E(85289): 0.00022
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:176-244)

         50        60        70        80        90       100      
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
                                     .:  .:.:.::. ::::: .  : : : :.
NP_005 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
         150       160       170       180       190       200     

        110        120       130       140       150       160     
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
       .:.. ... ...::.:     ::..   : :. .::.. :.                   
NP_005 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
         210       220         230       240       250       260   

         170       180       190       200       210       220     
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
                                                                   
NP_005 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
           270       280       290       300       310       320   

>>NP_001269635 (OMIM: 611099) protein disulfide-isomeras  (445 aa)
 initn: 131 init1: 106 opt: 228  Z-score: 244.8  bits: 55.1 E(85289): 6.7e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:25-173)

           30        40        50        60        70        80    
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
                                     :: ...:.. .  :.  :  . .:.. :::
NP_001       MYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
                     10        20        30        40         50   

           90       100       110       120       130       140    
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
       .::. :::::   .: :.  :  ..:   ...:.:.:   .:....  .: .. .::.. 
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
            60        70           80          90       100        

             150       160        170       180       190       200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
       :   :   ...  :.. ..  :  : ..:: . : : ... :       : :  . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
      110       120       130       140       150       160        

              210       220       230       240       250       260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
        : :.                                                       
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
      170       180       190       200       210       220        

>--
 initn: 157 init1: 104 opt: 186  Z-score: 199.6  bits: 46.8 E(85289): 0.00022
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:181-249)

         50        60        70        80        90       100      
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
                                     .:  .:.:.::. ::::: .  : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
              160       170       180       190       200       210

        110        120       130       140       150       160     
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
       .:.. ... ...::.:     ::..   : :. .::.. :.                   
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
              220         230       240       250       260        

         170       180       190       200       210       220     
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
                                                                   
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
      270       280       290       300       310       320        

>>NP_001269634 (OMIM: 611099) protein disulfide-isomeras  (488 aa)
 initn: 131 init1: 106 opt: 228  Z-score: 244.2  bits: 55.2 E(85289): 7.3e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:68-216)

           30        40        50        60        70        80    
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
                                     :: ...:.. .  :.  :  . .:.. :::
NP_001 SRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
        40        50        60        70        80         90      

           90       100       110       120       130       140    
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
       .::. :::::   .: :.  :  ..:   ...:.:.:   .:....  .: .. .::.. 
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
        100       110       120          130         140       150 

             150       160        170       180       190       200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
       :   :   ...  :.. ..  :  : ..:: . : : ... :       : :  . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
             160       170       180       190       200       210 

              210       220       230       240       250       260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
        : :.                                                       
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
             220       230       240       250       260       270 

>--
 initn: 157 init1: 104 opt: 186  Z-score: 199.0  bits: 46.8 E(85289): 0.00024
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:224-292)

         50        60        70        80        90       100      
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
                                     .:  .:.:.::. ::::: .  : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
           200       210       220       230       240       250   

        110        120       130       140       150       160     
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
       .:.. ... ...::.:     ::..   : :. .::.. :.                   
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
           260       270         280       290       300       310 

         170       180       190       200       210       220     
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
                                                                   
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
             320       330       340       350       360       370 

>>NP_001269633 (OMIM: 611099) protein disulfide-isomeras  (492 aa)
 initn: 131 init1: 106 opt: 228  Z-score: 244.2  bits: 55.2 E(85289): 7.3e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:72-220)

           30        40        50        60        70        80    
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
                                     :: ...:.. .  :.  :  . .:.. :::
NP_001 SRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
              50        60        70        80         90       100

           90       100       110       120       130       140    
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
       .::. :::::   .: :.  :  ..:   ...:.:.:   .:....  .: .. .::.. 
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
              110       120          130         140       150     

             150       160        170       180       190       200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
       :   :   ...  :.. ..  :  : ..:: . : : ... :       : :  . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
         160       170       180       190       200       210     

              210       220       230       240       250       260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
        : :.                                                       
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
         220       230       240       250       260       270     

>--
 initn: 157 init1: 104 opt: 186  Z-score: 198.9  bits: 46.8 E(85289): 0.00024
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:228-296)

         50        60        70        80        90       100      
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
                                     .:  .:.:.::. ::::: .  : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
       200       210       220       230       240       250       

        110        120       130       140       150       160     
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
       .:.. ... ...::.:     ::..   : :. .::.. :.                   
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
       260       270         280       290       300       310     

         170       180       190       200       210       220     
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
                                                                   
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
         320       330       340       350       360       370     

>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom  (508 aa)
 initn: 180 init1: 150 opt: 207  Z-score: 221.4  bits: 51.0 E(85289): 1.4e-05
Smith-Waterman score: 207; 38.0% identity (63.0% similar) in 100 aa overlap (60-155:23-119)

      30        40        50        60        70        80         
pF1KB6 AARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSS
                                     :: : :: ...   : : .    ::.::. 
NP_000         MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA-AHKYLLVEFYAP
                       10        20        30         40        50 

      90       100       110       120       130       140         
pF1KB6 WCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFK---
       ::::: . :: .   :: ..  .: ::.: .:  ::.. :  ..: .. :::...:.   
NP_000 WCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLA--QQYGVRGYPTIKFFRNGD
              60        70        80        90         100         

         150       160       170       180       190       200     
pF1KB6 -AFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDN
        :  ::.:.:                                                  
NP_000 TASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSA
     110       120       130       140       150       160         




698 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:22:09 2016 done: Sat Nov  5 07:22:11 2016
 Total Scan time: 12.920 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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