Result of FASTA (omim) for pF1KB4900
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4900, 542 aa
  1>>>pF1KB4900 542 - 542 aa - 542 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2830+/-0.00053; mu= 18.1618+/- 0.033
 mean_var=58.4146+/-12.135, 0's: 0 Z-trim(106.2): 53  B-trim: 0 in 0/49
 Lambda= 0.167808
 statistics sampled from 14269 (14316) to 14269 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.488), E-opt: 0.2 (0.168), width:  16
 Scan time:  9.280

The best scores are:                                      opt bits E(85289)
NP_004163 (OMIM: 600111,612656) excitatory amino a ( 542) 3412 835.2       0
XP_005248399 (OMIM: 600111,612656) PREDICTED: exci ( 542) 3412 835.2       0
NP_001276868 (OMIM: 600111,612656) excitatory amin ( 496) 2763 678.0 1.8e-194
XP_011512386 (OMIM: 600111,612656) PREDICTED: exci ( 435) 2739 672.2  9e-193
NP_001160167 (OMIM: 600111,612656) excitatory amin ( 497) 2707 664.5 2.2e-190
NP_004161 (OMIM: 133550,615232) excitatory amino a ( 524) 1702 421.2  4e-117
XP_011516310 (OMIM: 133550,615232) PREDICTED: exci ( 527) 1669 413.2  1e-114
XP_011516309 (OMIM: 133550,615232) PREDICTED: exci ( 547) 1669 413.2 1.1e-114
XP_016873627 (OMIM: 600300,617105) PREDICTED: exci ( 565) 1664 412.0 2.5e-114
NP_001239581 (OMIM: 600300,617105) excitatory amin ( 565) 1664 412.0 2.5e-114
NP_001182657 (OMIM: 600300,617105) excitatory amin ( 565) 1664 412.0 2.5e-114
XP_016873626 (OMIM: 600300,617105) PREDICTED: exci ( 565) 1664 412.0 2.5e-114
XP_011518587 (OMIM: 600300,617105) PREDICTED: exci ( 570) 1664 412.0 2.5e-114
XP_005253124 (OMIM: 600300,617105) PREDICTED: exci ( 571) 1664 412.0 2.5e-114
NP_004162 (OMIM: 600300,617105) excitatory amino a ( 574) 1664 412.0 2.5e-114
XP_016873625 (OMIM: 600300,617105) PREDICTED: exci ( 579) 1664 412.0 2.6e-114
XP_011516311 (OMIM: 133550,615232) PREDICTED: exci ( 504) 1662 411.5 3.2e-114
NP_001276869 (OMIM: 600111,612656) excitatory amin ( 430) 1605 397.7 3.9e-110
XP_011516312 (OMIM: 133550,615232) PREDICTED: exci ( 477) 1521 377.3 5.7e-104
XP_006722907 (OMIM: 600637) PREDICTED: excitatory  ( 564) 1513 375.4 2.5e-103
XP_016882641 (OMIM: 600637) PREDICTED: excitatory  ( 564) 1513 375.4 2.5e-103
NP_005062 (OMIM: 600637) excitatory amino acid tra ( 564) 1513 375.4 2.5e-103
XP_006722905 (OMIM: 600637) PREDICTED: excitatory  ( 564) 1513 375.4 2.5e-103
NP_001274526 (OMIM: 604471) excitatory amino acid  ( 472) 1226 305.9 1.8e-82
NP_006662 (OMIM: 604471) excitatory amino acid tra ( 560) 1220 304.5 5.7e-82
NP_003029 (OMIM: 600229,616657) neutral amino acid ( 532) 1041 261.1   6e-69
NP_005619 (OMIM: 109190) neutral amino acid transp ( 541) 1021 256.3 1.8e-67
NP_001138617 (OMIM: 109190) neutral amino acid tra ( 339) 1015 254.8 3.2e-67
XP_006712142 (OMIM: 600229,616657) PREDICTED: neut ( 312) 1004 252.1 1.9e-66
NP_001138616 (OMIM: 109190) neutral amino acid tra ( 313)  987 248.0 3.2e-65
XP_005259224 (OMIM: 109190) PREDICTED: neutral ami ( 469)  944 237.6 6.3e-62
XP_016870532 (OMIM: 133550,615232) PREDICTED: exci ( 488)  906 228.4 3.8e-59
XP_016870531 (OMIM: 133550,615232) PREDICTED: exci ( 511)  906 228.5   4e-59
NP_001259017 (OMIM: 600637) excitatory amino acid  ( 312)  860 217.2 5.8e-56
NP_001259016 (OMIM: 600637) excitatory amino acid  ( 312)  860 217.2 5.8e-56
XP_011540304 (OMIM: 604471) PREDICTED: excitatory  ( 337)  743 188.9 2.1e-47
NP_001274524 (OMIM: 604471) excitatory amino acid  ( 619)  743 189.0 3.6e-47
XP_016873628 (OMIM: 600300,617105) PREDICTED: exci ( 496)  694 177.1 1.1e-43
NP_001180422 (OMIM: 600229,616657) neutral amino a ( 234)  627 160.8 4.3e-39
NP_001274525 (OMIM: 604471) excitatory amino acid  ( 158)  467 122.0 1.4e-27
NP_001160168 (OMIM: 600111,612656) excitatory amin (  65)  380 100.8 1.4e-21


>>NP_004163 (OMIM: 600111,612656) excitatory amino acid   (542 aa)
 initn: 3412 init1: 3412 opt: 3412  Z-score: 4460.9  bits: 835.2 E(85289):    0
Smith-Waterman score: 3412; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542)

               10        20        30        40        50        60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
              490       500       510       520       530       540

         
pF1KB4 KM
       ::
NP_004 KM
         

>>XP_005248399 (OMIM: 600111,612656) PREDICTED: excitato  (542 aa)
 initn: 3412 init1: 3412 opt: 3412  Z-score: 4460.9  bits: 835.2 E(85289):    0
Smith-Waterman score: 3412; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542)

               10        20        30        40        50        60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
              490       500       510       520       530       540

         
pF1KB4 KM
       ::
XP_005 KM
         

>>NP_001276868 (OMIM: 600111,612656) excitatory amino ac  (496 aa)
 initn: 2763 init1: 2763 opt: 2763  Z-score: 3612.4  bits: 678.0 E(85289): 1.8e-194
Smith-Waterman score: 3017; 91.5% identity (91.5% similar) in 542 aa overlap (1-542:1-496)

               10        20        30        40        50        60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
       :                                              :::::::::::::
NP_001 G----------------------------------------------MAALDSKASGKMG
                                                             70    

              130       140       150       160       170       180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
           80        90       100       110       120       130    

              190       200       210       220       230       240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
          140       150       160       170       180       190    

              250       260       270       280       290       300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
          200       210       220       230       240       250    

              310       320       330       340       350       360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
          260       270       280       290       300       310    

              370       380       390       400       410       420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
          320       330       340       350       360       370    

              430       440       450       460       470       480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
          380       390       400       410       420       430    

              490       500       510       520       530       540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
          440       450       460       470       480       490    

         
pF1KB4 KM
       ::
NP_001 KM
         

>>XP_011512386 (OMIM: 600111,612656) PREDICTED: excitato  (435 aa)
 initn: 2739 init1: 2739 opt: 2739  Z-score: 3581.9  bits: 672.2 E(85289): 9e-193
Smith-Waterman score: 2739; 100.0% identity (100.0% similar) in 435 aa overlap (108-542:1-435)

        80        90       100       110       120       130       
pF1KB4 VKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVI
                                     ::::::::::::::::::::::::::::::
XP_011                               MAALDSKASGKMGMRAVVYYMTTTIIAVVI
                                             10        20        30

       140       150       160       170       180       190       
pF1KB4 GIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKR
               40        50        60        70        80        90

       200       210       220       230       240       250       
pF1KB4 SFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVI
              100       110       120       130       140       150

       260       270       280       290       300       310       
pF1KB4 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMY
              160       170       180       190       200       210

       320       330       340       350       360       370       
pF1KB4 TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLE
              220       230       240       250       260       270

       380       390       400       410       420       430       
pF1KB4 ENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAAS
              280       290       300       310       320       330

       440       450       460       470       480       490       
pF1KB4 IGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL
              340       350       360       370       380       390

       500       510       520       530       540  
pF1KB4 SRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
              400       410       420       430     

>>NP_001160167 (OMIM: 600111,612656) excitatory amino ac  (497 aa)
 initn: 3120 init1: 2707 opt: 2707  Z-score: 3539.1  bits: 664.5 E(85289): 2.2e-190
Smith-Waterman score: 3033; 91.5% identity (91.5% similar) in 542 aa overlap (1-542:1-497)

               10        20        30        40        50        60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
       :::::::::                                              :::::
NP_001 LNFGQIITIR---------------------------------------------DRLRT
              430                                                  

              490       500       510       520       530       540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
         440       450       460       470       480       490     

         
pF1KB4 KM
       ::
NP_001 KM
         

>>NP_004161 (OMIM: 133550,615232) excitatory amino acid   (524 aa)
 initn: 1656 init1: 916 opt: 1702  Z-score: 2223.8  bits: 421.2 E(85289): 4e-117
Smith-Waterman score: 1702; 55.2% identity (82.2% similar) in 493 aa overlap (45-534:14-501)

           20        30        40        50         60        70   
pF1KB4 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLL-TVTAVIVGTILGFTLRPYR-
                                     ...: .::: ::.::..:   :  .: .  
NP_004                  MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSN
                                10        20        30        40   

             80        90       100       110       120       130  
pF1KB4 MSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTI
       .:  :  ::.::::.:::::....:::::::..::.:::::..:::.:.::::::. ::.
NP_004 LSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTL
            50        60        70        80        90       100   

            140       150        160       170       180       190 
pF1KB4 IAVVIGIIIVIIIHPGKGTKEN-MHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFK
       :::..::..:. :.::   : . . : :.  .:...::.::::::::: :::.:::.:.:
NP_004 IAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYK
           110       120       130       140       150       160   

             200       210       220       230       240       250 
pF1KB4 TNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSM
       :. :.   : : . . ...   .. :  .  . .. :.:   :    .:.:.:::.:: .
NP_004 TKREE--VKPPSDPEMNMTEESFTAVMTTAISKNK-TKEYKIVGMYSDGINVLGLIVFCL
             170       180       190        200       210       220

             260       270       280       290       300       310 
pF1KB4 CFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIG
        ::.:::.: :.:: : .::..:..: :..: .:: : :.::::::::::.:.::  .. 
NP_004 VFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR
              230       240       250       260       270       280

             320       330       340       350       360       370 
pF1KB4 GQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPI
        .:..: .::..:: ::....:::.::.:.::::. :  :. :::.:::  ::::::::.
NP_004 -KLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPV
               290       300       310       320       330         

             380       390       400       410       420       430 
pF1KB4 TFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI
       ::.: :::: ::::.:::::::::::::::::::::.::.::::.:...:..::::::::
NP_004 TFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISI
     340       350       360       370       380       390         

             440       450       460       470       480       490 
pF1KB4 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGA
       :::.:::::::.::::::::::::..::::..:.::::::::.:::.:: .:::::..:.
NP_004 TATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGT
     400       410       420       430       440       450         

             500       510       520       530       540           
pF1KB4 GIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM         
       ::::.::..::.. ::    ....   ...   :  .:..:.:                 
NP_004 GIVEKLSKKELEQMDVSSEVNIVNPFALESTI-LDNEDSDTKKSYVNGGFAVDKSDTISF
     460       470       480       490        500       510        

NP_004 TQTSQF
      520    

>>XP_011516310 (OMIM: 133550,615232) PREDICTED: excitato  (527 aa)
 initn: 1656 init1: 916 opt: 1669  Z-score: 2180.5  bits: 413.2 E(85289): 1e-114
Smith-Waterman score: 1669; 55.0% identity (81.8% similar) in 484 aa overlap (53-534:26-504)

             30        40        50        60        70         80 
pF1KB4 RKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYR-MSYREVKYF
                                     :. ..: .:   :  .: .  .:  :  ::
XP_011      MTARRKFACRDCKPHGDPDHMSSTELSKVVVCTGITTGVLVREHSNLSTLEKFYF
                    10        20        30        40        50     

              90       100       110       120       130       140 
pF1KB4 SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIII
       .::::.:::::....:::::::..::.:::::..:::.:.::::::. ::.:::..::..
XP_011 AFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVL
          60        70        80        90       100       110     

             150        160       170       180       190       200
pF1KB4 VIIIHPGKGTKEN-MHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFK
       :. :.::   : . . : :.  .:...::.::::::::: :::.:::.:.::. :.   :
XP_011 VVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREE--VK
         120       130       140       150       160       170     

              210       220       230       240       250       260
pF1KB4 VPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNM
        : . . ...   .. :  .  . .. :.:   :    .:.:.:::.:: . ::.:::.:
XP_011 PPSDPEMNMTEESFTAVMTTAISKNK-TKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKM
           180       190        200       210       220       230  

              270       280       290       300       310       320
pF1KB4 KEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVT
        :.:: : .::..:..: :..: .:: : :.::::::::::.:.::  ..  .:..: .:
XP_011 GEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMAT
            240       250       260       270       280        290 

              330       340       350       360       370       380
pF1KB4 VIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENN
       :..:: ::....:::.::.:.::::. :  :. :::.:::  ::::::::.::.: ::::
XP_011 VLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENN
             300       310       320       330       340       350 

              390       400       410       420       430       440
pF1KB4 GVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGA
        ::::.:::::::::::::::::::::.::.::::.:...:..:::::::::::.:::::
XP_011 QVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGA
             360       370       380       390       400       410 

              450       460       470       480       490       500
pF1KB4 AGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRH
       ::.::::::::::::..::::..:.::::::::.:::.:: .:::::..:.::::.::..
XP_011 AGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK
             420       430       440       450       460       470 

              510       520       530       540                 
pF1KB4 ELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM               
       ::.. ::    ....   ...   :  .:..:.:                       
XP_011 ELEQMDVSSEVNIVNPFALESTI-LDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
             480       490        500       510       520       

>>XP_011516309 (OMIM: 133550,615232) PREDICTED: excitato  (547 aa)
 initn: 1656 init1: 916 opt: 1669  Z-score: 2180.3  bits: 413.2 E(85289): 1.1e-114
Smith-Waterman score: 1669; 55.0% identity (81.8% similar) in 484 aa overlap (53-534:46-524)

             30        40        50        60        70         80 
pF1KB4 RKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYR-MSYREVKYF
                                     :. ..: .:   :  .: .  .:  :  ::
XP_011 KNNWVLLSTVAAVVLDCKPHGDPDHMSSTELSKVVVCTGITTGVLVREHSNLSTLEKFYF
          20        30        40        50        60        70     

              90       100       110       120       130       140 
pF1KB4 SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIII
       .::::.:::::....:::::::..::.:::::..:::.:.::::::. ::.:::..::..
XP_011 AFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVL
          80        90       100       110       120       130     

             150        160       170       180       190       200
pF1KB4 VIIIHPGKGTKEN-MHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFK
       :. :.::   : . . : :.  .:...::.::::::::: :::.:::.:.::. :.   :
XP_011 VVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREE--VK
         140       150       160       170       180       190     

              210       220       230       240       250       260
pF1KB4 VPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNM
        : . . ...   .. :  .  . .. :.:   :    .:.:.:::.:: . ::.:::.:
XP_011 PPSDPEMNMTEESFTAVMTTAISKNK-TKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKM
           200       210        220       230       240       250  

              270       280       290       300       310       320
pF1KB4 KEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVT
        :.:: : .::..:..: :..: .:: : :.::::::::::.:.::  ..  .:..: .:
XP_011 GEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMAT
            260       270       280       290       300        310 

              330       340       350       360       370       380
pF1KB4 VIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENN
       :..:: ::....:::.::.:.::::. :  :. :::.:::  ::::::::.::.: ::::
XP_011 VLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENN
             320       330       340       350       360       370 

              390       400       410       420       430       440
pF1KB4 GVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGA
        ::::.:::::::::::::::::::::.::.::::.:...:..:::::::::::.:::::
XP_011 QVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGA
             380       390       400       410       420       430 

              450       460       470       480       490       500
pF1KB4 AGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRH
       ::.::::::::::::..::::..:.::::::::.:::.:: .:::::..:.::::.::..
XP_011 AGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK
             440       450       460       470       480       490 

              510       520       530       540                 
pF1KB4 ELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM               
       ::.. ::    ....   ...   :  .:..:.:                       
XP_011 ELEQMDVSSEVNIVNPFALESTI-LDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
             500       510        520       530       540       

>>XP_016873627 (OMIM: 600300,617105) PREDICTED: excitato  (565 aa)
 initn: 1514 init1: 1149 opt: 1664  Z-score: 2173.5  bits: 412.0 E(85289): 2.5e-114
Smith-Waterman score: 1664; 54.4% identity (80.4% similar) in 500 aa overlap (45-538:32-525)

           20        30        40        50        60        70    
pF1KB4 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMS
                                     : .: .. ::: .::.:.. :  ::     
XP_016 PKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPI
              10        20        30        40        50        60 

           80         90       100       110       120       130   
pF1KB4 YREVKYF-SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTII
       . .: .. .:::..:::::.::.::::::::.::...::.::::..: ::.::::.::::
XP_016 HPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTII
              70        80        90       100       110       120 

           140       150       160        170       180       190  
pF1KB4 AVVIGIIIVIIIHPGKGTKENMHREGKIV-RVTAADAFLDLIRNMFPPNLVEACFKQFKT
       :.:.:.:.:. ::::.   ...   ::   .:.. :::::::::.:: :::.:::.:..:
XP_016 AAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT
             130       140       150       160       170       180 

            200       210       220       230           240        
pF1KB4 NYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEE--LVPVPGSV--NGVNALGLVV
         .:     : . . . ..::   ::   ::.:.. ::  .:   :    .:.:.:::. 
XP_016 VTKKVLVAPPPDEEANATSAV---VSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIG
             190       200          210       220       230        

      250       260       270       280       290       300        
pF1KB4 FSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMG
       : . ::...:.: .:.. . .::. ::: .:.:: .::::.:.::  :: :::. ..:. 
XP_016 FFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLE
      240       250       260       270       280       290        

      310       320       330       340       350       360        
pF1KB4 VIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSAT
       :.. ::.:: ::::.::.::. : :::.::.::::::. :..:..:: ::::::.::..:
XP_016 VVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGT
      300       310       320       330       340       350        

      370       380       390       400       410       420        
pF1KB4 LPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIIT
       ::.::.::::: :.:::::::::::::::::::::::::.:::::::.:.  :. :::.:
XP_016 LPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVT
      360       370       380       390       400       410        

      430       440       450       460       470       480        
pF1KB4 ISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDS
       .:.::: ::.:::.::.::::::...::.:::::.::.:..::::.:::.::..::.:::
XP_016 VSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS
      420       430       440       450       460       470        

      490       500       510       520       530       540        
pF1KB4 LGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM      
       .::::: :::. :: . : .  . : :. :: :  : : .: ....  .:          
XP_016 FGAGIVYHLSKSELDTIDSQ--HRVHEDIEMTKT-QSIYDDMKNHRESNSNQCVYAAHNS
      480       490         500       510        520       530     

XP_016 VIVDECKVTLAANGKSADCSVEEEPWKREK
         540       550       560     

>>NP_001239581 (OMIM: 600300,617105) excitatory amino ac  (565 aa)
 initn: 1514 init1: 1149 opt: 1664  Z-score: 2173.5  bits: 412.0 E(85289): 2.5e-114
Smith-Waterman score: 1664; 54.4% identity (80.4% similar) in 500 aa overlap (45-538:32-525)

           20        30        40        50        60        70    
pF1KB4 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMS
                                     : .: .. ::: .::.:.. :  ::     
NP_001 PKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPI
              10        20        30        40        50        60 

           80         90       100       110       120       130   
pF1KB4 YREVKYF-SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTII
       . .: .. .:::..:::::.::.::::::::.::...::.::::..: ::.::::.::::
NP_001 HPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTII
              70        80        90       100       110       120 

           140       150       160        170       180       190  
pF1KB4 AVVIGIIIVIIIHPGKGTKENMHREGKIV-RVTAADAFLDLIRNMFPPNLVEACFKQFKT
       :.:.:.:.:. ::::.   ...   ::   .:.. :::::::::.:: :::.:::.:..:
NP_001 AAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT
             130       140       150       160       170       180 

            200       210       220       230           240        
pF1KB4 NYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEE--LVPVPGSV--NGVNALGLVV
         .:     : . . . ..::   ::   ::.:.. ::  .:   :    .:.:.:::. 
NP_001 VTKKVLVAPPPDEEANATSAV---VSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIG
             190       200          210       220       230        

      250       260       270       280       290       300        
pF1KB4 FSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMG
       : . ::...:.: .:.. . .::. ::: .:.:: .::::.:.::  :: :::. ..:. 
NP_001 FFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLE
      240       250       260       270       280       290        

      310       320       330       340       350       360        
pF1KB4 VIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSAT
       :.. ::.:: ::::.::.::. : :::.::.::::::. :..:..:: ::::::.::..:
NP_001 VVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGT
      300       310       320       330       340       350        

      370       380       390       400       410       420        
pF1KB4 LPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIIT
       ::.::.::::: :.:::::::::::::::::::::::::.:::::::.:.  :. :::.:
NP_001 LPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVT
      360       370       380       390       400       410        

      430       440       450       460       470       480        
pF1KB4 ISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDS
       .:.::: ::.:::.::.::::::...::.:::::.::.:..::::.:::.::..::.:::
NP_001 VSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS
      420       430       440       450       460       470        

      490       500       510       520       530       540        
pF1KB4 LGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM      
       .::::: :::. :: . : .  . : :. :: :  : : .: ....  .:          
NP_001 FGAGIVYHLSKSELDTIDSQ--HRVHEDIEMTKT-QSIYDDMKNHRESNSNQCVYAAHNS
      480       490         500       510        520       530     

NP_001 VIVDECKVTLAANGKSADCSVEEEPWKREK
         540       550       560     




542 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 06:05:59 2016 done: Sat Nov  5 06:06:01 2016
 Total Scan time:  9.280 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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