Result of FASTA (omim) for pF1KB4708
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4708, 444 aa
  1>>>pF1KB4708 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0400+/-0.000433; mu= 18.4644+/- 0.027
 mean_var=57.4569+/-12.231, 0's: 0 Z-trim(109.8): 37  B-trim: 509 in 1/49
 Lambda= 0.169201
 statistics sampled from 18058 (18086) to 18058 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.212), width:  16
 Scan time:  8.100

The best scores are:                                      opt bits E(85289)
NP_004256 (OMIM: 606149) fatty acid desaturase 2 i ( 444) 3118 769.8       0
NP_001268430 (OMIM: 606149) fatty acid desaturase  ( 422) 2641 653.3 3.4e-187
NP_001268431 (OMIM: 606149) fatty acid desaturase  ( 413) 2637 652.3 6.6e-187
NP_068373 (OMIM: 606150) fatty acid desaturase 3 [ ( 445) 2051 509.3 8.1e-144
XP_011543325 (OMIM: 606150) PREDICTED: fatty acid  ( 454) 2014 500.3 4.3e-141
NP_037534 (OMIM: 606148) fatty acid desaturase 1 [ ( 501) 1984 493.0 7.5e-139
XP_016873213 (OMIM: 606150) PREDICTED: fatty acid  ( 491) 1793 446.4  8e-125
XP_016873212 (OMIM: 606150) PREDICTED: fatty acid  ( 500) 1756 437.3 4.3e-122
XP_011543324 (OMIM: 606148) PREDICTED: fatty acid  ( 430) 1753 436.6 6.2e-122
NP_683725 (OMIM: 250790,613218) cytochrome b5 isof ( 134)  210 59.7 5.6e-09
NP_001177736 (OMIM: 250790,613218) cytochrome b5 i ( 124)  208 59.2 7.3e-09
XP_011524137 (OMIM: 250790,613218) PREDICTED: cyto (  98)  206 58.6 8.4e-09
NP_001905 (OMIM: 250790,613218) cytochrome b5 isof (  98)  206 58.6 8.4e-09
NP_085056 (OMIM: 611964) cytochrome b5 type B [Hom ( 150)  203 58.0   2e-08
NP_057314 (OMIM: 608343) cytochrome b5 reductase 4 ( 521)  165 49.0 3.6e-05


>>NP_004256 (OMIM: 606149) fatty acid desaturase 2 isofo  (444 aa)
 initn: 3118 init1: 3118 opt: 3118  Z-score: 4110.6  bits: 769.8 E(85289):    0
Smith-Waterman score: 3118; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)

               10        20        30        40        50        60
pF1KB4 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL
              370       380       390       400       410       420

              430       440    
pF1KB4 RALLDIIRSLKKSGKLWLDAYLHK
       ::::::::::::::::::::::::
NP_004 RALLDIIRSLKKSGKLWLDAYLHK
              430       440    

>>NP_001268430 (OMIM: 606149) fatty acid desaturase 2 is  (422 aa)
 initn: 2637 init1: 2637 opt: 2641  Z-score: 3481.7  bits: 653.3 E(85289): 3.4e-187
Smith-Waterman score: 2641; 96.7% identity (98.0% similar) in 393 aa overlap (53-444:35-422)

             30        40        50        60         70        80 
pF1KB4 WEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGH-YAGEDATDAFRAFHPDLEF
                                     ::..    ::  .:..  ::::::::::::
NP_001 EAGPFVCVCVLLASIPTPQTPLLQASLPPFHPASA---GHPITGQQ--DAFRAFHPDLEF
           10        20        30           40          50         

              90       100       110       120       130       140 
pF1KB4 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII
      60        70        80        90       100       110         

             150       160       170       180       190       200 
pF1KB4 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV
     120       130       140       150       160       170         

             210       220       230       240       250       260 
pF1KB4 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNH
     180       190       200       210       220       230         

             270       280       290       300       310       320 
pF1KB4 QHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALL
     240       250       260       270       280       290         

             330       340       350       360       370       380 
pF1KB4 FLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNF
     300       310       320       330       340       350         

             390       400       410       420       430       440 
pF1KB4 QIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAY
     360       370       380       390       400       410         

          
pF1KB4 LHK
       :::
NP_001 LHK
     420  

>>NP_001268431 (OMIM: 606149) fatty acid desaturase 2 is  (413 aa)
 initn: 2637 init1: 2637 opt: 2637  Z-score: 3476.6  bits: 652.3 E(85289): 6.6e-187
Smith-Waterman score: 2637; 100.0% identity (100.0% similar) in 375 aa overlap (70-444:39-413)

      40        50        60        70        80        90         
pF1KB4 DRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEP
                                     ::::::::::::::::::::::::::::::
NP_001 RRVNSLMLYTLRSITSHRSSHPERWATSSQDAFRAFHPDLEFVGKFLKPLLIGELAPEEP
       10        20        30        40        50        60        

     100       110       120       130       140       150         
pF1KB4 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI
       70        80        90       100       110       120        

     160       170       180       190       200       210         
pF1KB4 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ
      130       140       150       160       170       180        

     220       230       240       250       260       270         
pF1KB4 HHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYF
      190       200       210       220       230       240        

     280       290       300       310       320       330         
pF1KB4 QYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQ
      250       260       270       280       290       300        

     340       350       360       370       380       390         
pF1KB4 MNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKI
      310       320       330       340       350       360        

     400       410       420       430       440    
pF1KB4 APLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
       :::::::::::::::::::::::::::::::::::::::::::::
NP_001 APLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
      370       380       390       400       410   

>>NP_068373 (OMIM: 606150) fatty acid desaturase 3 [Homo  (445 aa)
 initn: 2076 init1: 1064 opt: 2051  Z-score: 2703.0  bits: 509.3 E(85289): 8.1e-144
Smith-Waterman score: 2051; 62.6% identity (84.1% similar) in 446 aa overlap (1-444:1-445)

                 10        20        30        40        50        
pF1KB4 MGKGGNQG--EGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQR
       ::  :. :  :: :.  . .::: ::.:. :.   :.::::.:.::.:..:. .::::.:
NP_068 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB4 VIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRK
       .:::...::::::::::: ::.:: :::.:::::::::::::::   :....::::::..
NP_068 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB4 TAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWL
       .::::.:: .. .:: .::.::.:.: .::. .. .: ::.:. ..::.:: ::::.  :
NP_068 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB4 QHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHV
       ::: :: :...:  :::...:::.:.::: ::.::: ::::::::::::::::::..  :
NP_068 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB4 FVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAW
       :.::: . .:::::: .:::::.:: ::::::::::  . :. . .  :.:  .:.:: :
NP_068 FLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLW
               250       260       270       280       290         

      300       310       320       330       340       350        
pF1KB4 AVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSS
       :.:.: :::..:.::::. :.:::.  .: ::::::::.::::::  :: .: .::: ::
NP_068 AASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSS
     300       310       320       330       340       350         

      360       370       380       390       400       410        
pF1KB4 QLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKP
       ::.:::::: :.:..:::::::::::::::: :::::  ..::::::::::::. :. ::
NP_068 QLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKP
     360       370       380       390       400       410         

      420       430       440    
pF1KB4 LLRALLDIIRSLKKSGKLWLDAYLHK
       .: ::.::.::::::: .:::::::.
NP_068 FLTALVDIVRSLKKSGDIWLDAYLHQ
     420       430       440     

>>XP_011543325 (OMIM: 606150) PREDICTED: fatty acid desa  (454 aa)
 initn: 2053 init1: 1064 opt: 2014  Z-score: 2654.0  bits: 500.3 E(85289): 4.3e-141
Smith-Waterman score: 2014; 61.1% identity (82.4% similar) in 455 aa overlap (1-444:1-454)

                 10        20        30        40        50        
pF1KB4 MGKGGNQG--EGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQR
       ::  :. :  :: :.  . .::: ::.:. :.   :.::::.:.::.:..:. .::::.:
XP_011 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB4 VIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRK
       .:::...::::::::::: ::.:: :::.:::::::::::::::   :....::::::..
XP_011 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB4 TAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWL
       .::::.:: .. .:: .::.::.:.: .::. .. .: ::.:. ..::.:: ::::.  :
XP_011 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB4 QHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHV
       ::: :: :...:  :::...:::.:.::: ::.::: ::::::::::::::::::..  :
XP_011 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB4 FVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAW
       :.::: . .:::::: .:::::.:: ::::::::::  . :. . .  :.:  .:.:: :
XP_011 FLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLW
               250       260       270       280       290         

      300       310       320       330       340       350        
pF1KB4 AVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSS
       :.:.: :::..:.::::. :.:::.  .: ::::::::.::::::  :: .: .::: ::
XP_011 AASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSS
     300       310       320       330       340       350         

      360       370       380                390       400         
pF1KB4 QLTATCNVEQSFFNDWFSGHLNFQIEHH---------LFPTMPRHNLHKIAPLVKSLCAK
       ::.:::::: :.:..::::::::::::.         ::: :::::  ..::::::::::
XP_011 QLAATCNVEPSLFTNWFSGHLNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAK
     360       370       380       390       400       410         

     410       420       430       440    
pF1KB4 HGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
       ::. :. ::.: ::.::.::::::: .:::::::.
XP_011 HGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
     420       430       440       450    

>>NP_037534 (OMIM: 606148) fatty acid desaturase 1 [Homo  (501 aa)
 initn: 2028 init1: 1030 opt: 1984  Z-score: 2613.8  bits: 493.0 E(85289): 7.5e-139
Smith-Waterman score: 1984; 63.4% identity (84.1% similar) in 440 aa overlap (11-444:64-501)

                                   10        20           30       
pF1KB4                     MGKGGNQGEGAAEREVSVPT---FSWEEIQKHNLRTDRWL
                                     :::  .. ::   :.:.:. ...   .:::
NP_037 WSPRTPSTRLTAPAGPARGVARPAMAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWL
            40        50        60        70        80        90   

        40        50        60        70        80        90       
pF1KB4 VIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPE
       :::::::::.... .::::.:::.::::.:::: : ::: .  .: :... ::::::.::
NP_037 VIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPE
           100       110       120       130       140       150   

       100       110       120       130       140       150       
pF1KB4 EPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNG
       .:: .  ::...:..:: :: :.: :.:.:.::::::: : ::. :.. ::.:.. ::..
NP_037 QPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTS
           160       170       180       190       200       210   

       160       170       180       190       200       210       
pF1KB4 WIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRH
       ..: :. : .:.. ::::::::::.:::::.   :::::.:.::::::::: :.:::: :
NP_037 FLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMH
           220       230       240       250       260       270   

       220       230         240       250       260       270     
pF1KB4 FQHHAKPNIFHKDPDVNMLH--VFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLI
       :::::::: :.::::.:: :   :.::.   .: ::.: ::.::::::.:::::::: :.
NP_037 FQHHAKPNCFRKDPDINM-HPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALL
           280       290        300       310       320       330  

         280       290       300       310       320        330    
pF1KB4 PMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFI-RFLESHWF
       :.:::. :.. .: .:.:::::: ...:.:::.::.:. : : :.: : :: :::::.::
NP_037 PLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLG-LKAFLGLFFIVRFLESNWF
            340       350       360       370        380       390 

          340       350       360       370       380       390    
pF1KB4 VWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRH
       ::::::::: :.::..   :: :.:: :::::..: ::::::::::::::::::::::::
NP_037 VWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRH
             400       410       420       430       440       450 

          400       410       420       430       440    
pF1KB4 NLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
       : ::.::::.::::::::::: :::: :. :::.:::.::.::::::::.
NP_037 NYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
             460       470       480       490       500 

>>XP_016873213 (OMIM: 606150) PREDICTED: fatty acid desa  (491 aa)
 initn: 1822 init1: 986 opt: 1793  Z-score: 2362.0  bits: 446.4 E(85289): 8e-125
Smith-Waterman score: 1793; 63.2% identity (83.5% similar) in 389 aa overlap (56-444:104-491)

          30        40        50        60        70        80     
pF1KB4 IQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKF
                                     :.:  :.   .   ::::::: ::.:: ::
XP_016 PPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKF
            80        90       100       110       120       130   

          90       100       110       120       130       140     
pF1KB4 LKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALES
       :.:::::::::::::::   :....::::::...::::.:: .. .:: .::.::.:.: 
XP_016 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
           140       150       160       170       180       190   

         150       160       170       180       190       200     
pF1KB4 IAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHL
       .::. .. .: ::.:. ..::.:: ::::.  :::: :: :...:  :::...:::.:.:
XP_016 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
           200       210       220       230       240       250   

         210       220       230       240       250       260     
pF1KB4 KGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEY
       :: ::.::: ::::::::::::::::::..  ::.::: . .:::::: .:::::.:: :
XP_016 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGE-SSVEYGKKKRRYLPYNQQHLY
           260       270       280       290        300       310  

         270       280       290       300       310       320     
pF1KB4 FFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNF
       :::::::::  . :. . .  :.:  .:.:: ::.:.: :::..:.::::. :.:::.  
XP_016 FFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVA
            320       330       340       350       360       370  

         330       340       350       360       370       380     
pF1KB4 IRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEH
       .: ::::::::.::::::  :: .: .::: ::::.:::::: :.:..::::::::::::
XP_016 VRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEH
            380       390       400       410       420       430  

         390       400       410       420       430       440    
pF1KB4 HLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
       :::: :::::  ..::::::::::::. :. ::.: ::.::.::::::: .:::::::.
XP_016 HLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
            440       450       460       470       480       490 

>>XP_016873212 (OMIM: 606150) PREDICTED: fatty acid desa  (500 aa)
 initn: 1799 init1: 810 opt: 1756  Z-score: 2313.0  bits: 437.3 E(85289): 4.3e-122
Smith-Waterman score: 1756; 61.6% identity (81.7% similar) in 398 aa overlap (56-444:104-500)

          30        40        50        60        70        80     
pF1KB4 IQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKF
                                     :.:  :.   .   ::::::: ::.:: ::
XP_016 PPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKF
            80        90       100       110       120       130   

          90       100       110       120       130       140     
pF1KB4 LKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALES
       :.:::::::::::::::   :....::::::...::::.:: .. .:: .::.::.:.: 
XP_016 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
           140       150       160       170       180       190   

         150       160       170       180       190       200     
pF1KB4 IAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHL
       .::. .. .: ::.:. ..::.:: ::::.  :::: :: :...:  :::...:::.:.:
XP_016 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
           200       210       220       230       240       250   

         210       220       230       240       250       260     
pF1KB4 KGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEY
       :: ::.::: ::::::::::::::::::..  ::.::: . .:::::: .:::::.:: :
XP_016 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGE-SSVEYGKKKRRYLPYNQQHLY
           260       270       280       290        300       310  

         270       280       290       300       310       320     
pF1KB4 FFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNF
       :::::::::  . :. . .  :.:  .:.:: ::.:.: :::..:.::::. :.:::.  
XP_016 FFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVA
            320       330       340       350       360       370  

         330       340       350       360       370       380     
pF1KB4 IRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEH
       .: ::::::::.::::::  :: .: .::: ::::.:::::: :.:..::::::::::::
XP_016 VRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEH
            380       390       400       410       420       430  

                  390       400       410       420       430      
pF1KB4 H---------LFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKL
       .         ::: :::::  ..::::::::::::. :. ::.: ::.::.::::::: .
XP_016 QCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDI
            440       450       460       470       480       490  

        440    
pF1KB4 WLDAYLHK
       :::::::.
XP_016 WLDAYLHQ
            500

>>XP_011543324 (OMIM: 606148) PREDICTED: fatty acid desa  (430 aa)
 initn: 1836 init1: 1030 opt: 1753  Z-score: 2310.1  bits: 436.6 E(85289): 6.2e-122
Smith-Waterman score: 1753; 64.8% identity (84.4% similar) in 378 aa overlap (70-444:55-430)

      40        50        60        70        80        90         
pF1KB4 DRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEP
                                     : : ::: .  .: :... ::::::.::.:
XP_011 PTRRITYRARGCRTCQRESYRHGPYLAQPKDPFVAFHINKGLVKKYMNSLLIGELSPEQP
           30        40        50        60        70        80    

     100       110       120       130       140       150         
pF1KB4 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI
       : .  ::...:..:: :: :.: :.:.:.::::::: : ::. :.. ::.:.. ::....
XP_011 SFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFL
           90       100       110       120       130       140    

     160       170       180       190       200       210         
pF1KB4 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ
       : :. : .:.. ::::::::::.:::::.   :::::.:.::::::::: :.:::: :::
XP_011 PFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQ
          150       160       170       180       190       200    

     220       230         240       250       260       270       
pF1KB4 HHAKPNIFHKDPDVNMLH--VFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPM
       :::::: :.::::.:: :   :.::.   .: ::.: ::.::::::.:::::::: :.:.
XP_011 HHAKPNCFRKDPDINM-HPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPL
          210       220        230       240       250       260   

       280       290       300       310       320        330      
pF1KB4 YFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFI-RFLESHWFVW
       :::. :.. .: .:.:::::: ...:.:::.::.:. : : :.: : :: :::::.::::
XP_011 YFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLG-LKAFLGLFFIVRFLESNWFVW
           270       280       290       300        310       320  

        340       350       360       370       380       390      
pF1KB4 VTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNL
       ::::::: :.::..   :: :.:: :::::..: ::::::::::::::::::::::::: 
XP_011 VTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNY
            330       340       350       360       370       380  

        400       410       420       430       440    
pF1KB4 HKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
       ::.::::.::::::::::: :::: :. :::.:::.::.::::::::.
XP_011 HKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
            390       400       410       420       430

>>NP_683725 (OMIM: 250790,613218) cytochrome b5 isoform   (134 aa)
 initn: 224 init1: 185 opt: 210  Z-score: 282.2  bits: 59.7 E(85289): 5.6e-09
Smith-Waterman score: 210; 35.6% identity (68.3% similar) in 101 aa overlap (11-110:2-101)

               10        20        30        40        50        60
pF1KB4 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
                 : . . .:  .. :::::::   . ::.. .:::..::.  .::::..:.
NP_683          MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVL
                        10        20        30        40        50 

               70        80        90        100       110         
pF1KB4 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEE-PSQDHGKNSKITEDFRALRKT
        . :: :::. :.    . . . .. : ..:::: :.. :. ..  .. ::         
NP_683 REQAGGDATENFEDVGHSTD-AREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWW
              60        70         80        90       100       110

     120       130       140       150       160       170         
pF1KB4 AEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQ
                                                                   
NP_683 TNWVIPAISAVAVALMYRLYMAED                                    
              120       130                                        




444 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 06:01:41 2016 done: Sat Nov  5 06:01:42 2016
 Total Scan time:  8.100 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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