Result of FASTA (ccds) for pF1KB4017
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4017, 464 aa
  1>>>pF1KB4017 464 - 464 aa - 464 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5887+/-0.000871; mu= 16.8260+/- 0.052
 mean_var=80.2896+/-15.401, 0's: 0 Z-trim(108.1): 23  B-trim: 114 in 1/49
 Lambda= 0.143135
 statistics sampled from 9953 (9966) to 9953 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.306), width:  16
 Scan time:  3.040

The best scores are:                                      opt bits E(32554)
CCDS47816.1 GFRA2 gene_id:2675|Hs108|chr8          ( 464) 3198 670.1 1.4e-192
CCDS55208.1 GFRA2 gene_id:2675|Hs108|chr8          ( 359) 2372 499.4 2.4e-141
CCDS55207.1 GFRA2 gene_id:2675|Hs108|chr8          ( 331) 2204 464.7 6.4e-131
CCDS44481.1 GFRA1 gene_id:2674|Hs108|chr10         ( 465) 1443 307.7 1.7e-83
CCDS7593.1 GFRA1 gene_id:2674|Hs108|chr10          ( 460) 1436 306.2 4.6e-83
CCDS13055.1 GFRA4 gene_id:64096|Hs108|chr20        ( 269)  617 136.9 2.4e-32
CCDS4201.1 GFRA3 gene_id:2676|Hs108|chr5           ( 400)  574 128.2 1.6e-29
CCDS13056.1 GFRA4 gene_id:64096|Hs108|chr20        ( 299)  343 80.4 2.8e-15
CCDS4957.1 GFRAL gene_id:389400|Hs108|chr6         ( 394)  283 68.1 1.9e-11


>>CCDS47816.1 GFRA2 gene_id:2675|Hs108|chr8               (464 aa)
 initn: 3198 init1: 3198 opt: 3198  Z-score: 3571.2  bits: 670.1 E(32554): 1.4e-192
Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)

               10        20        30        40        50        60
pF1KB4 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 EFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 YISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 CSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 IGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 VNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSM
              370       380       390       400       410       420

              430       440       450       460    
pF1KB4 CFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL
       ::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL
              430       440       450       460    

>>CCDS55208.1 GFRA2 gene_id:2675|Hs108|chr8               (359 aa)
 initn: 2372 init1: 2372 opt: 2372  Z-score: 2650.9  bits: 499.4 E(32554): 2.4e-141
Smith-Waterman score: 2372; 100.0% identity (100.0% similar) in 346 aa overlap (119-464:14-359)

       90       100       110       120       130       140        
pF1KB4 PLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGT
                                     ::::::::::::::::::::::::::::::
CCDS55                  MILANVFCLFFFLGEEFYEASPYEPVTSRLSDIFRLASIFSGT
                                10        20        30        40   

      150       160       170       180       190       200        
pF1KB4 GADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFF
            50        60        70        80        90       100   

      210       220       230       240       250       260        
pF1KB4 DRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRL
           110       120       130       140       150       160   

      270       280       290       300       310       320        
pF1KB4 ADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGS
           170       180       190       200       210       220   

      330       340       350       360       370       380        
pF1KB4 GNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDL
           230       240       250       260       270       280   

      390       400       410       420       430       440        
pF1KB4 SDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSGPSRARP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSGPSRARP
           290       300       310       320       330       340   

      450       460    
pF1KB4 SAALTVLSVLMLKLAL
       ::::::::::::::::
CCDS55 SAALTVLSVLMLKLAL
           350         

>>CCDS55207.1 GFRA2 gene_id:2675|Hs108|chr8               (331 aa)
 initn: 2198 init1: 2198 opt: 2204  Z-score: 2464.0  bits: 464.7 E(32554): 6.4e-131
Smith-Waterman score: 2204; 97.6% identity (98.8% similar) in 330 aa overlap (135-464:3-331)

          110       120       130       140       150       160    
pF1KB4 CLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDA
                                     :...: :  .: ::::::::::::::::::
CCDS55                             MILANVFCLF-FFLGTGADPVVSAKSNHCLDA
                                           10         20        30 

          170       180       190       200       210       220    
pF1KB4 AKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSC
              40        50        60        70        80        90 

          230       240       250       260       270       280    
pF1KB4 QDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTS
             100       110       120       130       140       150 

          290       300       310       320       330       340    
pF1KB4 CPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 CPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTE
             160       170       180       190       200       210 

          350       360       370       380       390       400    
pF1KB4 NPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTS
             220       230       240       250       260       270 

          410       420       430       440       450       460    
pF1KB4 VQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL
             280       290       300       310       320       330 

>>CCDS44481.1 GFRA1 gene_id:2674|Hs108|chr10              (465 aa)
 initn: 1379 init1: 612 opt: 1443  Z-score: 1612.6  bits: 307.7 E(32554): 1.7e-83
Smith-Waterman score: 1443; 49.8% identity (75.2% similar) in 436 aa overlap (38-460:27-452)

        10        20        30        40        50        60       
pF1KB4 CLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGR
                                     .:::.:.. :  :..::..:::::::.::.
CCDS44     MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGK
                   10        20        30        40        50      

        70             80        90       100       110       120  
pF1KB4 DRNTMLAN-----KECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEF
       . :  ::.      ::..:.:.:... ::.:::::::::: .::.::::.. .: .:...
CCDS44 ETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSL-QGNDL
         60        70        80        90       100       110      

            130       140       150       160       170       180  
pF1KB4 YEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYI
        : ::::::.::::::::.. ..: .  .     :.:.::::::::::.: ::: ::.::
CCDS44 LEDSPYEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYI
         120       130       140       150       160       170     

            190       200       210       220       230       240  
pF1KB4 SICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCS
       . :.  .: .. :::::::::::::::.::....: ::::::.: ::.:::::::.: ::
CCDS44 TPCTTSVS-NDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCS
         180        190       200       210       220       230    

            250       260       270       280       290       300  
pF1KB4 YEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIG
       ::..::::::.:.  :.:...:::::::: .::.   ..:.::  .::  :: .:.:.::
CCDS44 YEEREKPNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIG
          240       250       260       270       280       290    

            310       320       330       340       350       360  
pF1KB4 FDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVN
         :::::.:::  .. :.:::.: .:::  ::: :::  : .: ::.:::::::::.::.
CCDS44 TVMTPNYIDSS--SLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVT
          300         310       320       330       340       350  

                 370       380       390       400       410       
pF1KB4 V-SPKGP----SFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKE
       : .:  :    .  .: : ::.. :  :   .. . . : :.  :...: : ::.: : .
CCDS44 VWQPAFPVQTTTATTTTALRVKNKPLGPA--GSENEIPTHVLPPCANLQAQKLKSNVSGN
            360       370       380         390       400       410

       420          430       440       450       460             
pF1KB4 LSMCFTELT---TNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL         
         .:... .    ..  .:. . :  ..:    :: .:. : ::..             
CCDS44 THLCISNGNYEKEGLGASSHITTKSMAAP----PSCGLSPLLVLVVTALSTLLSLTETS
              420       430           440       450       460     

>>CCDS7593.1 GFRA1 gene_id:2674|Hs108|chr10               (460 aa)
 initn: 1385 init1: 612 opt: 1436  Z-score: 1604.8  bits: 306.2 E(32554): 4.6e-83
Smith-Waterman score: 1436; 49.8% identity (75.5% similar) in 436 aa overlap (38-460:27-447)

        10        20        30        40        50        60       
pF1KB4 CLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGR
                                     .:::.:.. :  :..::..:::::::.::.
CCDS75     MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGK
                   10        20        30        40        50      

        70             80        90       100       110       120  
pF1KB4 DRNTMLAN-----KECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEF
       . :  ::.      ::..:.:.:... ::.:::::::::: .::.::::.. .: .:...
CCDS75 ETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSL-QGNDL
         60        70        80        90       100       110      

            130       140       150       160       170       180  
pF1KB4 YEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYI
        : ::::::.::::::::.. ..:   .. .   :.:.::::::::::.: ::: ::.::
CCDS75 LEDSPYEPVNSRLSDIFRVVPFIS---VEHI--PKGNNCLDAAKACNLDDICKKYRSAYI
         120       130          140         150       160       170

            190       200       210       220       230       240  
pF1KB4 SICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCS
       . :.  .: .. :::::::::::::::.::....: ::::::.: ::.:::::::.: ::
CCDS75 TPCTTSVS-NDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCS
               180       190       200       210       220         

            250       260       270       280       290       300  
pF1KB4 YEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIG
       ::..::::::.:.  :.:...:::::::: .::.   ..:.::  .::  :: .:.:.::
CCDS75 YEEREKPNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIG
     230       240       250       260       270       280         

            310       320       330       340       350       360  
pF1KB4 FDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVN
         :::::.:::  .. :.:::.: .:::  ::: :::  : .: ::.:::::::::.::.
CCDS75 TVMTPNYIDSS--SLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVT
     290       300         310       320       330       340       

                 370       380       390       400       410       
pF1KB4 V-SPKGP----SFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKE
       : .:  :    .  .: : ::.. :  :   .. . . : :.  :...: : ::.: : .
CCDS75 VWQPAFPVQTTTATTTTALRVKNKPLGPA--GSENEIPTHVLPPCANLQAQKLKSNVSGN
       350       360       370         380       390       400     

       420          430       440       450       460             
pF1KB4 LSMCFTELT---TNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL         
         .:... .    ..  .:. . :  ..:    :: .:. : ::..             
CCDS75 THLCISNGNYEKEGLGASSHITTKSMAAP----PSCGLSPLLVLVVTALSTLLSLTETS
         410       420       430           440       450       460

>>CCDS13055.1 GFRA4 gene_id:64096|Hs108|chr20             (269 aa)
 initn: 505 init1: 249 opt: 617  Z-score: 694.1  bits: 136.9 E(32554): 2.4e-32
Smith-Waterman score: 617; 43.0% identity (69.1% similar) in 207 aa overlap (155-358:20-222)

          130       140       150       160       170       180    
pF1KB4 ASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISI
                                     :. .:.:.:::.::. .  :..::: :.. 
CCDS13            MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQ
                          10        20        30        40         

           190       200       210       220       230       240   
pF1KB4 C-NREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSY
       : .:  .    : : .:..:::.:: : :   :. .::: :   :::::::::..:::..
CCDS13 CLGRAAQGG--CPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAF
      50          60        70        80        90       100       

             250       260       270       280       290       300 
pF1KB4 EDK--EKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMI
              :.::.  . :. ...:: ::  :...:  . ..  .:  :.   :: .:::..
CCDS13 SGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCTPAPSAPDGCLLDQGARCLRAYAGLV
       110       120       130       140       150       160       

             310       320       330       340       350       360 
pF1KB4 GFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDV
       :  .::::::.  ..  :.:::.: .::: .:.:: :   ::.: :: .:::::..:   
CCDS13 GTAVTPNYVDN--VSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPP
       170         180       190       200       210       220     

             370       380       390       400       410       420 
pF1KB4 NVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSMC
                                                                   
CCDS13 VLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL                
         230       240       250       260                         

>>CCDS4201.1 GFRA3 gene_id:2676|Hs108|chr5                (400 aa)
 initn: 538 init1: 138 opt: 574  Z-score: 643.7  bits: 128.2 E(32554): 1.6e-29
Smith-Waterman score: 733; 34.6% identity (63.2% similar) in 370 aa overlap (40-394:44-393)

      10        20        30        40        50        60         
pF1KB4 FFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDR
                                     :..: . : :. .::. :. : .: ..   
CCDS42 VLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAYHHLDSCTSSI--
            20        30        40        50        60        70   

      70              80        90       100       110       120   
pF1KB4 NTMLANKE------CQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFY
       .: : ..:      :  : . :..: :  : :.: ::... ::.:::..: . . :.   
CCDS42 STPLPSEEPSVPADCLEAAQQLRNSSLIGCMCHRRMKNQVACLDIYWTVHRARSLGNYEL
              80        90       100       110       120       130 

           130       140       150       160       170       180   
pF1KB4 EASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYIS
       ..:::: ...     . :...        ...  :. ::  :  :.:::.: .::..:  
CCDS42 DVSPYEDTVTSKPWKMNLSKL-------NMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGE
             140       150              160       170       180    

           190       200       210       220         230       240 
pF1KB4 ICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSC--QDQACAERRRQTILPSC
        :.   .:  .:.:. : . :  ::...   ..  .:.: :  .:..:.::::.:: :.:
CCDS42 ACS---GP--HCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNC
               190       200       210       220       230         

             250       260       270       280       290       300 
pF1KB4 SYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMI
       .      ::::.:: .: .: ::::::.::...:.  .. . .: : . . :: .: :.:
CCDS42 ALPPVA-PNCLELRRLCFSDPLCRSRLVDFQTHCHP-MDILGTC-ATEQSRCLRAYLGLI
     240        250       260       270        280        290      

             310       320       330       340       350           
pF1KB4 GFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQA---FGNG
       :  ::::.:..  :....:  :.::::::..:::: .   :..:::: .:: :   : . 
CCDS42 GTAMTPNFVSNVNTSVALS--CTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQ
        300       310         320       330       340       350    

      360       370           380       390       400       410    
pF1KB4 TDVNVSPKGPSF----QATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANN
          .  :. :.:    . .. : :.  : .:. .: .  :                    
CCDS42 LFSQDWPH-PTFAVMAHQNENPAVRPQPWVPSLFSCTLPLILLLSLW             
          360        370       380       390       400             

          420       430       440       450       460    
pF1KB4 SKELSMCFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL

>>CCDS13056.1 GFRA4 gene_id:64096|Hs108|chr20             (299 aa)
 initn: 537 init1: 216 opt: 343  Z-score: 387.7  bits: 80.4 E(32554): 2.8e-15
Smith-Waterman score: 465; 36.7% identity (58.6% similar) in 237 aa overlap (155-358:20-252)

          130       140       150       160       170       180    
pF1KB4 ASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISI
                                     :. .:.:.:::.::. .  :..::: :.. 
CCDS13            MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQ
                          10        20        30        40         

           190       200       210       220       230       240   
pF1KB4 C-NREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSY
       : .:  .    : : .:..:::.:: : :   :. .::: :   :::::::::..:::..
CCDS13 CLGRAAQGG--CPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAF
      50          60        70        80        90       100       

             250       260                    270         280      
pF1KB4 EDK--EKPNCLDLRGVCRTDHLCR-SR------------LADFH--ANCRASYQTVTSC-
              :.::.  . :. ...:: .:            :.  :     .::   ...  
CCDS13 SGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLV
       110       120       130       140       150       160       

                      290       300        310       320       330 
pF1KB4 -------------PADNYQACLGSYAGM-IGFDMTPNYVDSSPTGIVVSPWCSCRGSGNM
                    :.    : : .  :.  :  .::::::.  ..  :.:::.: .::: 
CCDS13 HPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVTPNYVDN--VSARVAPWCDCGASGNR
       170       180       190       200         210       220     

             340       350       360       370       380       390 
pF1KB4 EEECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDS
       .:.:: :   ::.: :: .:::::..:                                 
CCDS13 REDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRS
         230       240       250       260       270       280     

>>CCDS4957.1 GFRAL gene_id:389400|Hs108|chr6              (394 aa)
 initn: 121 init1:  68 opt: 283  Z-score: 319.0  bits: 68.1 E(32554): 1.9e-11
Smith-Waterman score: 292; 24.5% identity (52.3% similar) in 331 aa overlap (44-348:15-317)

            20        30        40        50        60         70  
pF1KB4 DETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLR-QCLAGRDRNTM
                                     ::  .  .::.  :  :: :::  :: :  
CCDS49                 MIVFIFLAMGLSLENEYTSQTNNCT--Y--LREQCL--RDANG-
                               10        20            30          

             80             90       100        110       120      
pF1KB4 LANKECQAALEVLQES-----PLYDCRCKRGMKKELQC-LQIYWSIHLGLTEGEEFYEAS
            :. : .:....     :   :.    :..   : :.: . .. ..   : .   .
CCDS49 -----CKHAWRVMEDACNDSDPGDPCK----MRNSSYCNLSIQYLVESNFQFKECLCTDD
             40        50            60        70        80        

        130       140       150          160              170      
pF1KB4 PYEPVTSRLSDIFRLASIFSGTGADPV---VSAKSNH-------CLDAAKACNLNDNCKK
        :  :.. :.   .  .  ...  :     ....:.:       ::..:.::  .  :. 
CCDS49 FYCTVNKLLGK--KCINKSDNVKEDKFKWNLTTRSHHGFKGMWSCLEVAEACVGDVVCNA
       90         100       110       120       130       140      

        180       190       200       210       220         230    
pF1KB4 LRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSC--QDQACAERRR
         .::.. :. . .:   :. ..:. :.: :.. .: . .  . ::.:  .:  : . ..
CCDS49 QLASYLKACSANGNP---CDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKE
        150       160          170       180       190       200   

          240       250       260       270       280        290   
pF1KB4 QTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVT-SCPADNYQAC
            .:. .    :.::..   :..:.::: .   :...:   .: :: .:  :  . :
CCDS49 ALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKC---WQRVTRKCHED--ENC
           210       220       230       240          250          

           300            310       320       330        340       
pF1KB4 LGSYAGM----IGFD-MTPNYVDSSPTGIVVSPWCSCRGSGNMEEE-CEKFLRDFTENPC
       ... . .     : :     :.:    : :..  :.::   . ::  :. : . . .. :
CCDS49 ISTLSKQDLTCSGSDDCKAAYID--ILGTVLQVQCTCRTITQSEESLCKIFQHMLHRKSC
      260       270       280         290       300       310      

       350       360       370       380       390       400       
pF1KB4 LRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQE
       .                                                           
CCDS49 FNYPTLSNVKGMALYTRKHANKITLTGFHSPFNGEVIYAAMCMTVTCGILLLVMVKLRTS
        320       330       340       350       360       370      




464 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:32:39 2016 done: Sat Nov  5 05:32:39 2016
 Total Scan time:  3.040 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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