Result of FASTA (omim) for pF1KB3718
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3718, 165 aa
  1>>>pF1KB3718 165 - 165 aa - 165 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7402+/-0.000333; mu= 15.1569+/- 0.021
 mean_var=57.7870+/-11.569, 0's: 0 Z-trim(113.9): 23  B-trim: 114 in 1/49
 Lambda= 0.168717
 statistics sampled from 23444 (23467) to 23444 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.275), width:  16
 Scan time:  4.730

The best scores are:                                      opt bits E(85289)
XP_011527445 (OMIM: 609114) PREDICTED: destrin iso ( 165) 1109 277.8 5.5e-75
NP_006861 (OMIM: 609114) destrin isoform a [Homo s ( 165) 1109 277.8 5.5e-75
XP_011527444 (OMIM: 609114) PREDICTED: destrin iso ( 165) 1109 277.8 5.5e-75
XP_011527446 (OMIM: 609114) PREDICTED: destrin iso ( 148)  994 249.8 1.4e-66
NP_001011546 (OMIM: 609114) destrin isoform b [Hom ( 148)  994 249.8 1.4e-66
NP_005498 (OMIM: 601442) cofilin-1 [Homo sapiens]  ( 166)  780 197.7 7.1e-51
NP_619579 (OMIM: 601443,610687) cofilin-2 isoform  ( 166)  755 191.6 4.8e-49
NP_068733 (OMIM: 601443,610687) cofilin-2 isoform  ( 166)  755 191.6 4.8e-49
NP_001230574 (OMIM: 601443,610687) cofilin-2 isofo ( 149)  684 174.3 7.1e-44
XP_011534665 (OMIM: 601443,610687) PREDICTED: cofi ( 149)  684 174.3 7.1e-44
NP_009215 (OMIM: 607433) twinfilin-2 [Homo sapiens ( 349)  138 41.7  0.0014


>>XP_011527445 (OMIM: 609114) PREDICTED: destrin isoform  (165 aa)
 initn: 1109 init1: 1109 opt: 1109  Z-score: 1467.2  bits: 277.8 E(85289): 5.5e-75
Smith-Waterman score: 1109; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
               70        80        90       100       110       120

              130       140       150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
              130       140       150       160     

>>NP_006861 (OMIM: 609114) destrin isoform a [Homo sapie  (165 aa)
 initn: 1109 init1: 1109 opt: 1109  Z-score: 1467.2  bits: 277.8 E(85289): 5.5e-75
Smith-Waterman score: 1109; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
               70        80        90       100       110       120

              130       140       150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
       :::::::::::::::::::::::::::::::::::::::::::::
NP_006 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
              130       140       150       160     

>>XP_011527444 (OMIM: 609114) PREDICTED: destrin isoform  (165 aa)
 initn: 1109 init1: 1109 opt: 1109  Z-score: 1467.2  bits: 277.8 E(85289): 5.5e-75
Smith-Waterman score: 1109; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
               70        80        90       100       110       120

              130       140       150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
              130       140       150       160     

>>XP_011527446 (OMIM: 609114) PREDICTED: destrin isoform  (148 aa)
 initn: 994 init1: 994 opt: 994  Z-score: 1316.6  bits: 249.8 E(85289): 1.4e-66
Smith-Waterman score: 994; 100.0% identity (100.0% similar) in 148 aa overlap (18-165:1-148)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
                        :::::::::::::::::::::::::::::::::::::::::::
XP_011                  MKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
                                10        20        30        40   

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
            50        60        70        80        90       100   

              130       140       150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
           110       120       130       140        

>>NP_001011546 (OMIM: 609114) destrin isoform b [Homo sa  (148 aa)
 initn: 994 init1: 994 opt: 994  Z-score: 1316.6  bits: 249.8 E(85289): 1.4e-66
Smith-Waterman score: 994; 100.0% identity (100.0% similar) in 148 aa overlap (18-165:1-148)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
                        :::::::::::::::::::::::::::::::::::::::::::
NP_001                  MKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
                                10        20        30        40   

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
            50        60        70        80        90       100   

              130       140       150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
       :::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
           110       120       130       140        

>>NP_005498 (OMIM: 601442) cofilin-1 [Homo sapiens]       (166 aa)
 initn: 773 init1: 705 opt: 780  Z-score: 1034.3  bits: 197.7 E(85289): 7.1e-51
Smith-Waterman score: 780; 71.1% identity (86.7% similar) in 166 aa overlap (1-165:1-166)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
       ::::: :.: : ..: :::::: :::::.:::::::.:::: ::: ::.:::::::::::
NP_005 MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       : :. ::.  :: :::.::::::::::..:::::.::.:.:..:::: ::::::::::::
NP_005 GQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
               70        80        90       100       110       120

              130       140        150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDLNRAC-IAEKLGGSLIVAFEGCPV
       :::::::. ::::: :::  :...  : .::::::: ....:: :.
NP_005 KDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
              130       140       150       160      

>>NP_619579 (OMIM: 601443,610687) cofilin-2 isoform 1 [H  (166 aa)
 initn: 753 init1: 688 opt: 755  Z-score: 1001.4  bits: 191.6 E(85289): 4.8e-49
Smith-Waterman score: 755; 68.7% identity (87.3% similar) in 166 aa overlap (1-165:1-166)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
       ::::: : ::: ..: :::::: :: ::::::::::.:::: ::. :::::.:.:::::.
NP_619 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       : :. ::.  :: .:: .:::::::::..:::::.::.:.:..:::: ::::::::::::
NP_619 GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
               70        80        90       100       110       120

              130       140        150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDL-NRACIAEKLGGSLIVAFEGCPV
       :::::::: ::::: :.:: .:. .:. ..:::::...:..:: :.
NP_619 KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
              130       140       150       160      

>>NP_068733 (OMIM: 601443,610687) cofilin-2 isoform 1 [H  (166 aa)
 initn: 753 init1: 688 opt: 755  Z-score: 1001.4  bits: 191.6 E(85289): 4.8e-49
Smith-Waterman score: 755; 68.7% identity (87.3% similar) in 166 aa overlap (1-165:1-166)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
       ::::: : ::: ..: :::::: :: ::::::::::.:::: ::. :::::.:.:::::.
NP_068 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       : :. ::.  :: .:: .:::::::::..:::::.::.:.:..:::: ::::::::::::
NP_068 GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
               70        80        90       100       110       120

              130       140        150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDL-NRACIAEKLGGSLIVAFEGCPV
       :::::::: ::::: :.:: .:. .:. ..:::::...:..:: :.
NP_068 KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
              130       140       150       160      

>>NP_001230574 (OMIM: 601443,610687) cofilin-2 isoform 2  (149 aa)
 initn: 682 init1: 617 opt: 684  Z-score: 908.7  bits: 174.3 E(85289): 7.1e-44
Smith-Waterman score: 684; 69.1% identity (88.6% similar) in 149 aa overlap (18-165:1-149)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
                        ::::: :: ::::::::::.:::: ::. :::::.:.:::::.
NP_001                  MKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI
                                10        20        30        40   

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       : :. ::.  :: .:: .:::::::::..:::::.::.:.:..:::: ::::::::::::
NP_001 GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
            50        60        70        80        90       100   

              130       140        150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDL-NRACIAEKLGGSLIVAFEGCPV
       :::::::: ::::: :.:: .:. .:. ..:::::...:..:: :.
NP_001 KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
           110       120       130       140         

>>XP_011534665 (OMIM: 601443,610687) PREDICTED: cofilin-  (149 aa)
 initn: 682 init1: 617 opt: 684  Z-score: 908.7  bits: 174.3 E(85289): 7.1e-44
Smith-Waterman score: 684; 69.1% identity (88.6% similar) in 149 aa overlap (18-165:1-149)

               10        20        30        40        50        60
pF1KB3 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
                        ::::: :: ::::::::::.:::: ::. :::::.:.:::::.
XP_011                  MKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI
                                10        20        30        40   

               70        80        90       100       110       120
pF1KB3 GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
       : :. ::.  :: .:: .:::::::::..:::::.::.:.:..:::: ::::::::::::
XP_011 GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
            50        60        70        80        90       100   

              130       140        150       160     
pF1KB3 KDAIKKKFQGIKHECQANGPEDL-NRACIAEKLGGSLIVAFEGCPV
       :::::::: ::::: :.:: .:. .:. ..:::::...:..:: :.
XP_011 KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
           110       120       130       140         




165 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:20:06 2016 done: Sat Nov  5 05:20:07 2016
 Total Scan time:  4.730 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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