Result of FASTA (omim) for pF1KB3489
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3489, 332 aa
  1>>>pF1KB3489 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0807+/-0.00038; mu= 17.4716+/- 0.024
 mean_var=65.6698+/-12.937, 0's: 0 Z-trim(112.2): 144  B-trim: 0 in 0/53
 Lambda= 0.158267
 statistics sampled from 20838 (20988) to 20838 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.246), width:  16
 Scan time:  7.720

The best scores are:                                      opt bits E(85289)
NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine  ( 332) 2116 492.0 7.2e-139
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 1645 384.5 1.6e-106
XP_016881179 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 255) 1632 381.4 1.1e-105
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310)  310 79.6 9.3e-15
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325)  310 79.7 9.6e-15
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325)  310 79.7 9.6e-15
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334)  310 79.7 9.9e-15
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372)  310 79.7 1.1e-14
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372)  310 79.7 1.1e-14
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289)  296 76.4   8e-14
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339)  296 76.5 9.1e-14
NP_001207422 (OMIM: 616161) dehydrogenase/reductas ( 312)  295 76.2   1e-13
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404)  296 76.5 1.1e-13
NP_001099041 (OMIM: 616161) dehydrogenase/reductas ( 311)  294 76.0 1.2e-13
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331)  292 75.6 1.7e-13
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309)  277 72.1 1.7e-12
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318)  277 72.1 1.8e-12
NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292)  263 68.9 1.5e-11
NP_001193670 (OMIM: 600713,614662) corticosteroid  ( 292)  263 68.9 1.5e-11
NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292)  263 68.9 1.5e-11
NP_000405 (OMIM: 233400,261515,601860) peroxisomal ( 736)  264 69.4 2.7e-11
NP_057110 (OMIM: 607849,616108) retinol dehydrogen ( 318)  246 65.0 2.4e-10
NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312)  240 63.7   6e-10
NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302)  232 61.8 2.1e-09
NP_000404 (OMIM: 109684) estradiol 17-beta-dehydro ( 328)  232 61.9 2.2e-09
XP_016873370 (OMIM: 609574) PREDICTED: very-long-c ( 280)  231 61.6 2.3e-09
XP_011523032 (OMIM: 109684) PREDICTED: estradiol 1 ( 383)  232 61.9 2.5e-09
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278)  229 61.1 3.1e-09
XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324)  229 61.2 3.6e-09
XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324)  229 61.2 3.6e-09
XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  229 61.2 3.6e-09
XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  229 61.2 3.6e-09
XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  229 61.2 3.6e-09
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  228 60.9 3.7e-09
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  228 60.9 3.7e-09
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280)  228 60.9 3.7e-09
NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  229 61.2 3.7e-09
XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343)  229 61.2 3.7e-09
XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343)  229 61.2 3.7e-09
NP_976060 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  229 61.2 3.7e-09
NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  229 61.2 3.7e-09
XP_011511369 (OMIM: 603063) PREDICTED: D-beta-hydr ( 347)  229 61.2 3.8e-09
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300)  228 60.9 3.9e-09
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300)  226 60.5 5.4e-09
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303)  226 60.5 5.4e-09
NP_689656 (OMIM: 608830,612712) retinol dehydrogen ( 316)  224 60.0 7.7e-09
NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260)  222 59.5   9e-09
NP_001317148 (OMIM: 109684) estradiol 17-beta-dehy ( 329)  222 59.6 1.1e-08
XP_011523031 (OMIM: 109684) PREDICTED: estradiol 1 ( 384)  222 59.6 1.2e-08
XP_005257349 (OMIM: 109684) PREDICTED: estradiol 1 ( 359)  216 58.2   3e-08


>>NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine redu  (332 aa)
 initn: 2116 init1: 2116 opt: 2116  Z-score: 2614.1  bits: 492.0 E(85289): 7.2e-139
Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)

               10        20        30        40        50        60
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
              250       260       270       280       290       300

              310       320       330  
pF1KB3 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
       ::::::::::::::::::::::::::::::::
NP_002 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
              310       320       330  

>>XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihydrosp  (298 aa)
 initn: 1880 init1: 1645 opt: 1645  Z-score: 2033.6  bits: 384.5 E(85289): 1.6e-106
Smith-Waterman score: 1816; 89.8% identity (89.8% similar) in 332 aa overlap (1-332:1-298)

               10        20        30        40        50        60
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
       :::::::::::::::::::                                  :::::::
XP_005 TTSVCKPEQVAKQIVKDAI----------------------------------VVTMGLF
              250                                         260      

              310       320       330  
pF1KB3 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
       ::::::::::::::::::::::::::::::::
XP_005 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
        270       280       290        

>>XP_016881179 (OMIM: 136440) PREDICTED: 3-ketodihydrosp  (255 aa)
 initn: 1632 init1: 1632 opt: 1632  Z-score: 2018.5  bits: 381.4 E(85289): 1.1e-105
Smith-Waterman score: 1632; 100.0% identity (100.0% similar) in 255 aa overlap (78-332:1-255)

        50        60        70        80        90       100       
pF1KB3 IAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MHSINDKQVVLCISVDVSQDYNQVENVIKQ
                                             10        20        30

       110       120       130       140       150       160       
pF1KB3 AQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGR
               40        50        60        70        80        90

       170       180       190       200       210       220       
pF1KB3 IVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEE
              100       110       120       130       140       150

       230       240       250       260       270       280       
pF1KB3 NRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSI
              160       170       180       190       200       210

       290       300       310       320       330  
pF1KB3 TEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
              220       230       240       250     

>>NP_001317088 (OMIM: 616160) dehydrogenase/reductase SD  (310 aa)
 initn: 308 init1: 234 opt: 310  Z-score: 385.9  bits: 79.6 E(85289): 9.3e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:35-222)

                10        20        30        40        50         
pF1KB3  MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
                                     : .: ::.::..::.::  :   :  :: .
NP_001 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
           10        20        30        40        50        60    

      60        70        80          90       100       110       
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
       .: .::   : .  .:.     .  :.     .. :.. : . .  .  .  . .: ::.
NP_001 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
           70        80        90       100        110       120   

       120       130       140       150       160       170       
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
       ::: ::..  : . :  :.. .:.:  ::.: :  ..:.. .: .:: :.:: .::  :.
NP_001 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
           130       140       150       160       170       180   

       180       190       200       210       220       230       
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
       ...   .::.::: : ... . :. :.. :.. .::  :                     
NP_001 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
           190       200       210       220       230       240   

       240       250       260       270       280       290       
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
                                                                   
NP_001 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
           250       260       270       280       290       300   

>>XP_016879915 (OMIM: 616160) PREDICTED: dehydrogenase/r  (325 aa)
 initn: 308 init1: 234 opt: 310  Z-score: 385.7  bits: 79.7 E(85289): 9.6e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:50-237)

                10        20        30        40        50         
pF1KB3  MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
                                     : .: ::.::..::.::  :   :  :: .
XP_016 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
      20        30        40        50        60        70         

      60        70        80          90       100       110       
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
       .: .::   : .  .:.     .  :.     .. :.. : . .  .  .  . .: ::.
XP_016 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
      80        90       100       110        120       130        

       120       130       140       150       160       170       
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
       ::: ::..  : . :  :.. .:.:  ::.: :  ..:.. .: .:: :.:: .::  :.
XP_016 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
      140       150       160       170       180       190        

       180       190       200       210       220       230       
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
       ...   .::.::: : ... . :. :.. :.. .::  :                     
XP_016 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
      200       210       220       230       240       250        

       240       250       260       270       280       290       
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
                                                                   
XP_016 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
      260       270       280       290       300       310        

>>NP_056325 (OMIM: 616160) dehydrogenase/reductase SDR f  (325 aa)
 initn: 308 init1: 234 opt: 310  Z-score: 385.7  bits: 79.7 E(85289): 9.6e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:50-237)

                10        20        30        40        50         
pF1KB3  MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
                                     : .: ::.::..::.::  :   :  :: .
NP_056 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
      20        30        40        50        60        70         

      60        70        80          90       100       110       
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
       .: .::   : .  .:.     .  :.     .. :.. : . .  .  .  . .: ::.
NP_056 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
      80        90       100       110        120       130        

       120       130       140       150       160       170       
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
       ::: ::..  : . :  :.. .:.:  ::.: :  ..:.. .: .:: :.:: .::  :.
NP_056 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
      140       150       160       170       180       190        

       180       190       200       210       220       230       
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
       ...   .::.::: : ... . :. :.. :.. .::  :                     
NP_056 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
      200       210       220       230       240       250        

       240       250       260       270       280       290       
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
                                                                   
NP_056 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
      260       270       280       290       300       310        

>>XP_011522088 (OMIM: 616160) PREDICTED: dehydrogenase/r  (334 aa)
 initn: 302 init1: 228 opt: 310  Z-score: 385.5  bits: 79.7 E(85289): 9.9e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:97-284)

                10        20        30        40        50         
pF1KB3  MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
                                     : .: ::.::..::.::  :   :  :: .
XP_011 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
         70        80        90       100       110       120      

      60        70        80          90       100       110       
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
       .: .::   : .  .:.     .  :.     .. :.. : . .  .  .  . .: ::.
XP_011 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
        130       140       150       160        170       180     

       120       130       140       150       160       170       
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
       ::: ::..  : . :  :.. .:.:  ::.: :  ..:.. .: .:: :.:: .::  :.
XP_011 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
         190       200       210       220       230       240     

       180       190       200       210       220       230       
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
       ...   .::.::: : ... . :. :.. :.. .::  :                     
XP_011 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSSYGH
         250       260       270       280       290       300     

       240       250       260       270       280       290       
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
                                                                   
XP_011 HHSPGPKPCGGGPGCSCCCGEEEERCDPG                               
         310       320       330                                   

>>XP_016879914 (OMIM: 616160) PREDICTED: dehydrogenase/r  (372 aa)
 initn: 308 init1: 234 opt: 310  Z-score: 384.8  bits: 79.7 E(85289): 1.1e-14
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:97-284)

                10        20        30        40        50         
pF1KB3  MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
                                     : .: ::.::..::.::  :   :  :: .
XP_016 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
         70        80        90       100       110       120      

      60        70        80          90       100       110       
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
       .: .::   : .  .:.     .  :.     .. :.. : . .  .  .  . .: ::.
XP_016 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
        130       140       150       160        170       180     

       120       130       140       150       160       170       
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
       ::: ::..  : . :  :.. .:.:  ::.: :  ..:.. .: .:: :.:: .::  :.
XP_016 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
         190       200       210       220       230       240     

       180       190       200       210       220       230       
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
       ...   .::.::: : ... . :. :.. :.. .::  :                     
XP_016 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
         250       260       270       280       290       300     

       240       250       260       270       280       290       
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
                                                                   
XP_016 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
         310       320       330       340       350       360     

>>XP_005256652 (OMIM: 616160) PREDICTED: dehydrogenase/r  (372 aa)
 initn: 308 init1: 234 opt: 310  Z-score: 384.8  bits: 79.7 E(85289): 1.1e-14
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:97-284)

                10        20        30        40        50         
pF1KB3  MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
                                     : .: ::.::..::.::  :   :  :: .
XP_005 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
         70        80        90       100       110       120      

      60        70        80          90       100       110       
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
       .: .::   : .  .:.     .  :.     .. :.. : . .  .  .  . .: ::.
XP_005 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
        130       140       150       160        170       180     

       120       130       140       150       160       170       
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
       ::: ::..  : . :  :.. .:.:  ::.: :  ..:.. .: .:: :.:: .::  :.
XP_005 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
         190       200       210       220       230       240     

       180       190       200       210       220       230       
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
       ...   .::.::: : ... . :. :.. :.. .::  :                     
XP_005 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
         250       260       270       280       290       300     

       240       250       260       270       280       290       
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
                                                                   
XP_005 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
         310       320       330       340       350       360     

>>NP_001309209 (OMIM: 612833) dehydrogenase/reductase SD  (289 aa)
 initn: 256 init1: 177 opt: 296  Z-score: 369.1  bits: 76.4 E(85289): 8e-14
Smith-Waterman score: 305; 27.7% identity (59.8% similar) in 264 aa overlap (35-294:3-234)

           10        20        30        40        50        60    
pF1KB3 AAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVAR
                                     : :::.:::::. .: .  : :. ..: ::
NP_001                             MVVWVTGASSGIGEELAYQLSKLGVSLVLSAR
                                           10        20        30  

           70         80        90       100       110       120   
pF1KB3 NEDKLLQAKKE-IEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAG
          .: ..:.. .:  ....:.. : . .:.. : .. : . : . ...: .:.::: .:
NP_001 RVHELERVKRRCLENGNLKEKDI-LVLPLDLT-DTGSHEAATKAVLQEFGRIDILVNNGG
             40        50         60         70        80        90

           130       140       150       160       170       180   
pF1KB3 MAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGF
       :.  .   :  ......:. .::::.:  .. :.  : ::. :.:: :.:  : ...   
NP_001 MSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLS
              100       110       120       130       140       150

           190       200       210       220       230       240   
pF1KB3 TAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTS
        .: ::: :.::. ..:. :.  :              ::.   :               
NP_001 IGYCASKHALRGFFNGLRTELATY--------------PGIIVSN---------------
              160       170                     180                

           250       260       270          280       290       300
pF1KB3 VCKPEQVAKQIVKDAIQGNFNSSLGSDG---YMLSALTCGMAPVTSITEGLQQVVTMGLF
       .: :  : ..::.... :. ....:..:   . ...  :    . :... :..:      
NP_001 IC-PGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQP
              190       200       210       220       230       240

              310       320       330                   
pF1KB3 RTIALFYLGSFDSIVRRCMMQREKSENADKTA                 
                                                        
NP_001 FLLVTYLWQYMPTWAWWITNKMGKKRIENFKSGVDADSSYFKIFKTKHD
              250       260       270       280         




332 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:11:21 2016 done: Sat Nov  5 05:11:22 2016
 Total Scan time:  7.720 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com