Result of FASTA (omim) for pF1KB3393
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3393, 308 aa
  1>>>pF1KB3393 308 - 308 aa - 308 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.2139+/-0.000396; mu= 21.6942+/- 0.025
 mean_var=57.1306+/-12.190, 0's: 0 Z-trim(111.5): 16  B-trim: 300 in 3/49
 Lambda= 0.169684
 statistics sampled from 20068 (20083) to 20068 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.235), width:  16
 Scan time:  5.920

The best scores are:                                      opt bits E(85289)
NP_612510 (OMIM: 610057,614020) very-long-chain en ( 308) 2140 532.1 5.3e-151
XP_011526744 (OMIM: 610057,614020) PREDICTED: very ( 329) 2105 523.6 2.1e-148
NP_001308099 (OMIM: 610057,614020) very-long-chain ( 323) 2103 523.1 2.9e-148
XP_006723008 (OMIM: 610057,614020) PREDICTED: very ( 341) 2013 501.1 1.3e-141
NP_000339 (OMIM: 264600,607306) 3-oxo-5-alpha-ster ( 254)  230 64.5 2.6e-10
XP_011531371 (OMIM: 264600,607306) PREDICTED: 3-ox ( 180)  226 63.3 4.1e-10
XP_011531374 (OMIM: 264600,607306) PREDICTED: 3-ox ( 169)  222 62.3 7.7e-10
NP_001311252 (OMIM: 184753) 3-oxo-5-alpha-steroid  ( 186)  203 57.7 2.1e-08
NP_001038 (OMIM: 184753) 3-oxo-5-alpha-steroid 4-d ( 259)  204 58.1 2.2e-08
NP_001311251 (OMIM: 184753) 3-oxo-5-alpha-steroid  ( 212)  189 54.3 2.4e-07
XP_016864090 (OMIM: 611715,612379,612713) PREDICTE ( 273)  130 40.0  0.0065
NP_078868 (OMIM: 611715,612379,612713) polyprenol  ( 318)  130 40.1  0.0072


>>NP_612510 (OMIM: 610057,614020) very-long-chain enoyl-  (308 aa)
 initn: 2140 init1: 2140 opt: 2140  Z-score: 2831.9  bits: 532.1 E(85289): 5.3e-151
Smith-Waterman score: 2140; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308)

               10        20        30        40        50        60
pF1KB3 MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 DEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLR
              250       260       270       280       290       300

               
pF1KB3 MPIIPFLL
       ::::::::
NP_612 MPIIPFLL
               

>>XP_011526744 (OMIM: 610057,614020) PREDICTED: very-lon  (329 aa)
 initn: 2105 init1: 2105 opt: 2105  Z-score: 2785.2  bits: 523.6 E(85289): 2.1e-148
Smith-Waterman score: 2105; 99.7% identity (100.0% similar) in 304 aa overlap (5-308:26-329)

                                    10        20        30         
pF1KB3                      MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKT
                                .::::::::::::::::::::::::::::::::::
XP_011 MVQQLMKAQGQDLETRVRRGGEEVCQVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKT
               10        20        30        40        50        60

      40        50        60        70        80        90         
pF1KB3 HPQWYPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPQWYPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPL
               70        80        90       100       110       120

     100       110       120       130       140       150         
pF1KB3 FIYLLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIYLLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLR
              130       140       150       160       170       180

     160       170       180       190       200       210         
pF1KB3 NIFKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIFKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLR
              190       200       210       220       230       240

     220       230       240       250       260       270         
pF1KB3 PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMT
              250       260       270       280       290       300

     280       290       300        
pF1KB3 IWAKGKHRSYLKEFRDYPPLRMPIIPFLL
       :::::::::::::::::::::::::::::
XP_011 IWAKGKHRSYLKEFRDYPPLRMPIIPFLL
              310       320         

>>NP_001308099 (OMIM: 610057,614020) very-long-chain eno  (323 aa)
 initn: 2103 init1: 2103 opt: 2103  Z-score: 2782.7  bits: 523.1 E(85289): 2.9e-148
Smith-Waterman score: 2103; 100.0% identity (100.0% similar) in 303 aa overlap (6-308:21-323)

                              10        20        30        40     
pF1KB3                MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYP
                           ::::::::::::::::::::::::::::::::::::::::
NP_001 MILQETKAACGIPAIPHCSRVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYP
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB3 ARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLF
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB3 YFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNC
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KB3 TYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKT
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KB3 RKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGK
              250       260       270       280       290       300

         290       300        
pF1KB3 HRSYLKEFRDYPPLRMPIIPFLL
       :::::::::::::::::::::::
NP_001 HRSYLKEFRDYPPLRMPIIPFLL
              310       320   

>>XP_006723008 (OMIM: 610057,614020) PREDICTED: very-lon  (341 aa)
 initn: 2019 init1: 1996 opt: 2013  Z-score: 2663.3  bits: 501.1 E(85289): 1.3e-141
Smith-Waterman score: 2013; 98.0% identity (98.6% similar) in 296 aa overlap (13-308:47-341)

                                 10        20        30        40  
pF1KB3                   MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQ
                                     :  .:::  .::::::::::::::::::::
XP_006 LWHSSDSSLLKGGDSGRKDKGEAVFLGQELTSLRLCF-PQVEPHATIAEIKNLFTKTHPQ
         20        30        40        50         60        70     

             50        60        70        80        90       100  
pF1KB3 WYPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WYPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIY
          80        90       100       110       120       130     

            110       120       130       140       150       160  
pF1KB3 LLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIF
         140       150       160       170       180       190     

            170       180       190       200       210       220  
pF1KB3 KNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAG
         200       210       220       230       240       250     

            230       240       250       260       270       280  
pF1KB3 SKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWA
         260       270       280       290       300       310     

            290       300        
pF1KB3 KGKHRSYLKEFRDYPPLRMPIIPFLL
       ::::::::::::::::::::::::::
XP_006 KGKHRSYLKEFRDYPPLRMPIIPFLL
         320       330       340 

>>NP_000339 (OMIM: 264600,607306) 3-oxo-5-alpha-steroid   (254 aa)
 initn: 209 init1: 178 opt: 230  Z-score: 306.0  bits: 64.5 E(85289): 2.6e-10
Smith-Waterman score: 234; 28.3% identity (58.2% similar) in 184 aa overlap (127-308:82-254)

        100       110       120       130       140       150      
pF1KB3 GPLFIYLLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTM
                                     : :. .:  .::..: .   ...:     .
NP_000 AWFLQELPSFAVPAGILARQPLSLFGPPGTVLLGLFC--LHYFHRTFVYSLLNR--GRPY
              60        70        80          90       100         

        160       170       180       190       200       210      
pF1KB3 PLRNIFKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIH--MA
       :   :... ..  : .. ..::. .    :  . .. ....:..:..    ...::  . 
NP_000 PAILILRGTAFCTGNGVLQGYYLIYCAEYPDGWYTD-IRFSLGVFLFILGMGINIHSDYI
       110       120       130       140        150       160      

          220       230       240       250       260       270    
pF1KB3 LRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVG
       ::.::  :  . .::         ::  ::  :.  :.  :::.:. :  ::.  :.. .
NP_000 LRQLRKPGEISYRIPQGG------LFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFS
        170       180             190       200       210       220

          280       290       300        
pF1KB3 FTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL
       .  . . :  .:: ::: :.:::  :  .:::..
NP_000 LCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF
              230       240       250    

>>XP_011531371 (OMIM: 264600,607306) PREDICTED: 3-oxo-5-  (180 aa)
 initn: 209 init1: 178 opt: 226  Z-score: 302.6  bits: 63.3 E(85289): 4.1e-10
Smith-Waterman score: 226; 27.4% identity (58.7% similar) in 179 aa overlap (133-308:13-180)

            110       120       130       140       150        160 
pF1KB3 LLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGT-MPLRNI
                                     :...  .: .. .:.    ..:  .:   :
XP_011                   MTSQGMPRTANHCQKLGTLKTFVYSLL----NRGRPYPAILI
                                 10        20            30        

             170       180       190       200       210           
pF1KB3 FKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIH--MALRDLR
       ... ..  : .. ..::. .    :  . .. ....:..:..    ...::  . ::.::
XP_011 LRGTAFCTGNGVLQGYYLIYCAEYPDGWYTD-IRFSLGVFLFILGMGINIHSDYILRQLR
       40        50        60         70        80        90       

     220       230       240       250       260       270         
pF1KB3 PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMT
         :  . .::         ::  ::  :.  :.  :::.:. :  ::.  :.. ..  . 
XP_011 KPGEISYRIPQGG------LFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLG
       100       110             120       130       140       150 

     280       290       300        
pF1KB3 IWAKGKHRSYLKEFRDYPPLRMPIIPFLL
       . :  .:: ::: :.:::  :  .:::..
XP_011 LRAFHHHRFYLKMFEDYPKSRKALIPFIF
             160       170       180

>>XP_011531374 (OMIM: 264600,607306) PREDICTED: 3-oxo-5-  (169 aa)
 initn: 209 init1: 178 opt: 222  Z-score: 297.7  bits: 62.3 E(85289): 7.7e-10
Smith-Waterman score: 222; 29.3% identity (59.3% similar) in 150 aa overlap (161-308:27-169)

              140       150       160       170       180       190
pF1KB3 CICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYINHPLYTPPTYG
                                     :... ..  : .. ..::. .    :  . 
XP_011     MRSWSLTYRTFVYSLLNRGRPYPAILILRGTAFCTGNGVLQGYYLIYCAEYPDGWY
                   10        20        30        40        50      

              200       210         220       230       240        
pF1KB3 AQQVKLALAIFVICQLGNFSIH--MALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNY
       .. ....:..:..    ...::  . ::.::  :  . .::         ::  ::  :.
XP_011 TD-IRFSLGVFLFILGMGINIHSDYILRQLRKPGEISYRIPQGG------LFTYVSGANF
          60        70        80        90             100         

      250       260       270       280       290       300        
pF1KB3 TYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL
         :.  :::.:. :  ::.  :.. ..  . . :  .:: ::: :.:::  :  .:::..
XP_011 LGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF
     110       120       130       140       150       160         

>>NP_001311252 (OMIM: 184753) 3-oxo-5-alpha-steroid 4-de  (186 aa)
 initn: 198 init1: 163 opt: 203  Z-score: 272.0  bits: 57.7 E(85289): 2.1e-08
Smith-Waterman score: 203; 27.9% identity (52.5% similar) in 179 aa overlap (135-308:16-186)

          110       120       130       140       150       160    
pF1KB3 FYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKN
                                     ::  .  ::. :.   . .:  :.   .  
NP_001                MTLPWRTWSEWKQITSFTVFPALLRCLIYPFLMRGGKPM--PLLA
                              10        20        30          40   

          170           180        190       200       210         
pF1KB3 CTYYWGFAAWMAY----YINH-PLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLR
       ::.   : .  .:    :..:  .:.       .  .......  .: :.     ::.::
NP_001 CTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLR
            50        60        70        80        90       100   

     220       230       240       250       260       270         
pF1KB3 PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMT
         :.   :::         ::  :.  ::  :.  : :.:. .  .  : :..  :  ..
NP_001 KPGDTGYKIPRGG------LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLS
           110             120       130       140       150       

     280       290       300        
pF1KB3 IWAKGKHRSYLKEFRDYPPLRMPIIPFLL
         :: .:. ::..:..:: .:  :::::.
NP_001 GRAKEHHEWYLRKFEEYPKFRKIIIPFLF
       160       170       180      

>>NP_001038 (OMIM: 184753) 3-oxo-5-alpha-steroid 4-dehyd  (259 aa)
 initn: 225 init1: 163 opt: 204  Z-score: 271.5  bits: 58.1 E(85289): 2.2e-08
Smith-Waterman score: 205; 28.7% identity (52.2% similar) in 178 aa overlap (137-308:94-259)

        110       120       130       140       150       160      
pF1KB3 FRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRN-----I
                                     :: .: :   :. : .   :::       .
NP_001 LALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMR-GGKPMPLLACTMAIM
            70        80        90       100        110       120  

             170       180        190       200       210       220
pF1KB3 FKNCTYYWGFAAWMAYYINH-PLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRP
       : .:. :      .. :..:  .:.       .  .......  .: :.     ::.:: 
NP_001 FCTCNGY-----LQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRK
                 130       140       150       160       170       

              230       240       250       260       270       280
pF1KB3 AGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTI
        :.   :::         ::  :.  ::  :.  : :.:. .  .  : :..  :  .. 
NP_001 PGDTGYKIPRGG------LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSG
       180             190       200       210       220       230 

              290       300        
pF1KB3 WAKGKHRSYLKEFRDYPPLRMPIIPFLL
        :: .:. ::..:..:: .:  :::::.
NP_001 RAKEHHEWYLRKFEEYPKFRKIIIPFLF
             240       250         

>>NP_001311251 (OMIM: 184753) 3-oxo-5-alpha-steroid 4-de  (212 aa)
 initn: 198 init1: 163 opt: 189  Z-score: 252.8  bits: 54.3 E(85289): 2.4e-07
Smith-Waterman score: 189; 31.9% identity (57.5% similar) in 113 aa overlap (196-308:106-212)

         170       180       190       200       210       220     
pF1KB3 TYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKT
                                     .......  .: :.     ::.::  :.  
NP_001 RSTSTPASPPRVSAARPTASSWPCSSSTTGIGFGLWLTGMLINIHSDHILRNLRKPGDTG
          80        90       100       110       120       130     

         230       240       250       260       270       280     
pF1KB3 RKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGK
        :::         ::  :.  ::  :.  : :.:. .  .  : :..  :  ..  :: .
NP_001 YKIPRGG------LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEH
         140             150       160       170       180         

         290       300        
pF1KB3 HRSYLKEFRDYPPLRMPIIPFLL
       :. ::..:..:: .:  :::::.
NP_001 HEWYLRKFEEYPKFRKIIIPFLF
     190       200       210  




308 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:57:24 2016 done: Sat Nov  5 04:57:25 2016
 Total Scan time:  5.920 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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