Result of FASTA (omim) for pF1KE0932
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0932, 411 aa
  1>>>pF1KE0932 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9982+/-0.000424; mu= 12.0655+/- 0.026
 mean_var=176.5542+/-37.506, 0's: 0 Z-trim(117.0): 24  B-trim: 875 in 2/54
 Lambda= 0.096524
 statistics sampled from 28609 (28633) to 28609 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.336), width:  16
 Scan time:  8.890

The best scores are:                                      opt bits E(85289)
NP_068780 (OMIM: 108985,189967) transcriptional en ( 426) 2784 399.9 6.1e-111
NP_003204 (OMIM: 601714) transcriptional enhancer  ( 434) 2137 309.8 8.1e-84
XP_006723491 (OMIM: 601729) PREDICTED: transcripti ( 434) 1608 236.2 1.2e-61
NP_958851 (OMIM: 601714) transcriptional enhancer  ( 305) 1529 225.0   2e-58
NP_003205 (OMIM: 603170) transcriptional enhancer  ( 435) 1513 222.9 1.2e-57
NP_958849 (OMIM: 601714) transcriptional enhancer  ( 391) 1434 211.9 2.2e-54
XP_011525706 (OMIM: 601729) PREDICTED: transcripti ( 441) 1119 168.1 3.9e-41
XP_011525708 (OMIM: 601729) PREDICTED: transcripti ( 228)  687 107.6 3.2e-23
XP_011525707 (OMIM: 601729) PREDICTED: transcripti ( 231)  681 106.8 5.8e-23
XP_006723492 (OMIM: 601729) PREDICTED: transcripti ( 261)  676 106.2   1e-22
NP_001243591 (OMIM: 601729) transcriptional enhanc ( 319)  676 106.2 1.2e-22
XP_005259391 (OMIM: 601729) PREDICTED: transcripti ( 411)  676 106.4 1.4e-22
NP_003589 (OMIM: 601729) transcriptional enhancer  ( 447)  676 106.4 1.5e-22
XP_011525705 (OMIM: 601729) PREDICTED: transcripti ( 450)  676 106.4 1.5e-22
NP_001243587 (OMIM: 601729) transcriptional enhanc ( 450)  676 106.4 1.5e-22
NP_001243588 (OMIM: 601729) transcriptional enhanc ( 450)  676 106.4 1.5e-22
NP_001243590 (OMIM: 601729) transcriptional enhanc ( 451)  676 106.4 1.5e-22
NP_001243589 (OMIM: 601729) transcriptional enhanc ( 451)  676 106.4 1.5e-22
XP_006723487 (OMIM: 601729) PREDICTED: transcripti ( 451)  676 106.4 1.5e-22
XP_011525703 (OMIM: 601729) PREDICTED: transcripti ( 454)  676 106.4 1.5e-22
XP_011525701 (OMIM: 601729) PREDICTED: transcripti ( 454)  676 106.4 1.5e-22
XP_011525704 (OMIM: 601729) PREDICTED: transcripti ( 454)  676 106.4 1.5e-22
XP_011525700 (OMIM: 601729) PREDICTED: transcripti ( 454)  676 106.4 1.5e-22
XP_011525702 (OMIM: 601729) PREDICTED: transcripti ( 454)  676 106.4 1.5e-22


>>NP_068780 (OMIM: 108985,189967) transcriptional enhanc  (426 aa)
 initn: 2784 init1: 2784 opt: 2784  Z-score: 2112.8  bits: 399.9 E(85289): 6.1e-111
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:16-426)

                              10        20        30        40     
pF1KE0                MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL
                      :::::::::::::::::::::::::::::::::::::::::::::
NP_068 MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE0 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KE0 HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KE0 PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KE0 HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KE0 DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE
              310       320       330       340       350       360

         350       360       370       380       390       400     
pF1KE0 YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI
              370       380       390       400       410       420

         410 
pF1KE0 YRLVKD
       ::::::
NP_068 YRLVKD
             

>>NP_003204 (OMIM: 601714) transcriptional enhancer fact  (434 aa)
 initn: 2102 init1: 1953 opt: 2137  Z-score: 1625.7  bits: 309.8 E(85289): 8.1e-84
Smith-Waterman score: 2137; 77.2% identity (90.5% similar) in 412 aa overlap (5-411:28-434)

                                      10        20        30       
pF1KE0                        MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPP
                                  :.. :::::::::::::::::::::::::::::
NP_003 MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPP
               10        20        30        40        50        60

        40        50        60        70        80        90       
pF1KE0 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQ
       :::::::::::::::::::::::::::::::::::::::::::::::::.:....:::::
NP_003 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQ
               70        80        90       100       110       120

       100       110       120       130       140       150       
pF1KE0 TAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDV
       .::::::: :::::::::.::::.:....:     :  :.. ::: : .  :: :.:.::
NP_003 AAKDKALQSMAAMSSAQIISATAFHSSMALA--RGPGRPAVSGFWQGALP-GQAGTSHDV
              130       140       150         160        170       

       160       170       180            190       200       210  
pF1KE0 KPFVQQAYPIQPAVTAPIPGFEPASAPAPS-----VPAWQGRSIGTTKLRLVEFSAFLEQ
       ::: ::.: .:: .  :.::::  ..::::     .: :::::....:: ..::::::::
NP_003 KPFSQQTYAVQPPL--PLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQ
       180       190         200       210       220       230     

            220       230       240       250       260       270  
pF1KE0 QRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFL
       :.:::.::::::::::... ::::: ::.::::::::::::::::::.:: .::.:::::
NP_003 QQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFL
         240       250       260       270       280       290     

            280       290       300       310       320       330  
pF1KE0 VKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENG
       :::::::: ::.:....::::.::::: ::: .:::::::::::::::::::::::.:::
NP_003 VKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENG
         300       310       320       330       340       350     

            340       350       360       370       380       390  
pF1KE0 RFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVF
       .. :::.:::.:::::::::::::::::::::::::::::: :::::::::::::.: ::
NP_003 HYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVF
         360       370       380       390       400       410     

            400       410 
pF1KE0 EVSNSEHGAQHHIYRLVKD
       ::: ::::::::::::::.
NP_003 EVSASEHGAQHHIYRLVKE
         420       430    

>>XP_006723491 (OMIM: 601729) PREDICTED: transcriptional  (434 aa)
 initn: 1675 init1: 640 opt: 1608  Z-score: 1227.6  bits: 236.2 E(85289): 1.2e-61
Smith-Waterman score: 1677; 64.3% identity (78.5% similar) in 428 aa overlap (5-411:30-434)

                                        10        20        30     
pF1KE0                          MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY
                                    :..:      :::::::::::::::::::::
XP_006 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::...::::
XP_006 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK
               70        80        90       100       110       120

         100       110       120       130          140       150  
pF1KE0 DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAP---GFWPGMIQTGQPG
       ::..::::.: ::.:::::..:: ... :::      :: : :     :: :   .: : 
XP_006 DQVSKDKAFQTMATMSSAQLISAPSLQAKLG------PTGPQASELFQFWSG--GSGPPW
              130       140       150             160         170  

            160       170          180             190       200   
pF1KE0 SSQDVKPFVQQAYPIQPAVTAP---IPGFEPASA------PAPSVPAWQGRSIGTTKLRL
       .  ::::: :   :.  ..: :   .::.:: .:      :.:: ::::.:..::..:.:
XP_006 NVPDVKPFSQT--PFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQL
            180         190       200       210       220       230

           210       220       230       240       250       260   
pF1KE0 VEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFG
       ::::::.:     :::..::::::..   : . : :::::.::::::::::::::.::. 
XP_006 VEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYD
              240       250       260       270       280       290

           270       280                290       300       310    
pF1KE0 KGPQNAFFLVKFWADLNCNIQ-DDAGA--------FYGVTSQYESSENMTVTCSTKVCSF
       .:: .:::::::::::: . . ..:::        ::::.::::: :.::.:::.:    
XP_006 RGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSK----
              300       310       320       330       340          

          320       330       340       350       360       370    
pF1KE0 GKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILL
                :: :..:.::::::. :::::::..::.:::..:::.::::::::::::: 
XP_006 ---------TERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQ
                 350       360       370       380       390       

          380       390       400       410 
pF1KE0 VVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD
       ::::::::: ::: : :::::.::.::::::::::.:
XP_006 VVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD
       400       410       420       430    

>>NP_958851 (OMIM: 601714) transcriptional enhancer fact  (305 aa)
 initn: 1498 init1: 1349 opt: 1529  Z-score: 1170.0  bits: 225.0 E(85289): 2e-58
Smith-Waterman score: 1529; 73.0% identity (88.1% similar) in 311 aa overlap (107-411:1-305)

         80        90       100       110       120        130     
pF1KE0 SHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLP-GIPRPTF
                                     :::::::::.::::.:....:  :   :  
NP_958                               MAAMSSAQIISATAFHSSMALARG---PGR
                                             10        20          

         140       150       160       170       180            190
pF1KE0 PGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPS-----VPA
       :.. ::: : .  :: :.:.::::: ::.: .:: .  :.::::  ..::::     .: 
NP_958 PAVSGFWQGALP-GQAGTSHDVKPFSQQTYAVQPPL--PLPGFESPAGPAPSPSAPPAPP
        30         40        50        60          70        80    

              200       210       220       230       240       250
pF1KE0 WQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDK
       :::::....:: ..:::::::::.:::.::::::::::... ::::: ::.:::::::::
NP_958 WQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDK
           90       100       110       120       130       140    

              260       270       280       290       300       310
pF1KE0 FPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTK
       :::::::::.:: .::.::::::::::::: ::.:....::::.::::: ::: .:::::
NP_958 FPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTK
          150       160       170       180       190       200    

              320       330       340       350       360       370
pF1KE0 VCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENF
       ::::::::::::::::::.:::.. :::.:::.:::::::::::::::::::::::::::
NP_958 VCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENF
          210       220       230       240       250       260    

              380       390       400       410 
pF1KE0 TILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD
       ::: :::::::::::::.: ::::: ::::::::::::::.
NP_958 TILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
          270       280       290       300     

>>NP_003205 (OMIM: 603170) transcriptional enhancer fact  (435 aa)
 initn: 1869 init1: 1242 opt: 1513  Z-score: 1156.1  bits: 222.9 E(85289): 1.2e-57
Smith-Waterman score: 2011; 73.1% identity (87.9% similar) in 413 aa overlap (9-411:24-435)

                              10        20        30        40     
pF1KE0                MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL
                              :: .:::::::::::::::::::::::::::::::::
NP_003 MASNSWNASSSPGEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL
               10        20        30        40        50        60

          50        60        70        80        90           100 
pF1KE0 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK----DQTAKD
       :::::::::::::::::::::::::::::::::::::::.: :...  .:    ::..::
NP_003 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKD
               70        80        90       100       110       120

             110       120        130       140       150          
pF1KE0 KALQHMAAMSSAQIVSATAIHNKLGLPG-IPRPTFPGAPGFWPGMIQTGQ-PGSSQDVKP
       :::: ::.:::::::::....::.. :. .:. .:  .  :: .    :: :: :::.::
NP_003 KALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKP
              130       140       150       160       170       180

     160       170       180           190       200       210     
pF1KE0 FVQQAYPIQPAVTAPIPGFEPASAPAPS----VPAWQGRSIGTTKLRLVEFSAFLEQQRD
       :.: :::::: .   . ..::  :: ::    ::.:: :.:....:::.:.:::.: :::
NP_003 FAQPAYPIQPPLPPTLSSYEPL-APLPSAAASVPVWQDRTIASSRLRLLEYSAFMEVQRD
              190       200        210       220       230         

         220       230       240       250       260       270     
pF1KE0 PDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKF
       ::.:.::::::::..: ..::: ::.::.:::::::::::::::::. ::: ::::::::
NP_003 PDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKF
     240       250       260       270       280       290         

         280       290       300       310       320       330     
pF1KE0 WADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFV
       ::::: .::.  ::::::.::: :...::.. :::::::::::::::::::::.::::::
NP_003 WADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFV
     300       310       320       330       340       350         

         340       350       360       370       380       390     
pF1KE0 YRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVS
       :::.:::::::::::::::::::::::::::::::::: :::.::.::::: .: :::::
NP_003 YRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVS
     360       370       380       390       400       410         

         400       410 
pF1KE0 NSEHGAQHHIYRLVKD
       .::::::::.:.::::
NP_003 TSEHGAQHHVYKLVKD
     420       430     

>>NP_958849 (OMIM: 601714) transcriptional enhancer fact  (391 aa)
 initn: 1946 init1: 1284 opt: 1434  Z-score: 1097.2  bits: 211.9 E(85289): 2.2e-54
Smith-Waterman score: 1886; 70.6% identity (81.8% similar) in 412 aa overlap (5-411:28-391)

                                      10        20        30       
pF1KE0                        MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPP
                                  :.. :::::::::::::::::::::::::::::
NP_958 MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPP
               10        20        30        40        50        60

        40        50        60        70        80        90       
pF1KE0 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQ
       :::::::::::::::::::::::::::::::::::::::::::::::::.:....:::  
NP_958 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLK--
               70        80        90       100       110          

       100       110       120       130       140       150       
pF1KE0 TAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDV
                                                  :: : .  :: :.:.::
NP_958 -------------------------------------------FWQGALP-GQAGTSHDV
                                                 120        130    

       160       170       180            190       200       210  
pF1KE0 KPFVQQAYPIQPAVTAPIPGFEPASAPAPS-----VPAWQGRSIGTTKLRLVEFSAFLEQ
       ::: ::.: .:: .  :.::::  ..::::     .: :::::....:: ..::::::::
NP_958 KPFSQQTYAVQPPL--PLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQ
          140         150       160       170       180       190  

            220       230       240       250       260       270  
pF1KE0 QRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFL
       :.:::.::::::::::... ::::: ::.::::::::::::::::::.:: .::.:::::
NP_958 QQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFL
            200       210       220       230       240       250  

            280       290       300       310       320       330  
pF1KE0 VKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENG
       :::::::: ::.:....::::.::::: ::: .:::::::::::::::::::::::.:::
NP_958 VKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENG
            260       270       280       290       300       310  

            340       350       360       370       380       390  
pF1KE0 RFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVF
       .. :::.:::.:::::::::::::::::::::::::::::: :::::::::::::.: ::
NP_958 HYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVF
            320       330       340       350       360       370  

            400       410 
pF1KE0 EVSNSEHGAQHHIYRLVKD
       ::: ::::::::::::::.
NP_958 EVSASEHGAQHHIYRLVKE
            380       390 

>>XP_011525706 (OMIM: 601729) PREDICTED: transcriptional  (441 aa)
 initn: 1661 init1: 512 opt: 1119  Z-score: 859.5  bits: 168.1 E(85289): 3.9e-41
Smith-Waterman score: 1653; 63.4% identity (77.6% similar) in 429 aa overlap (5-411:30-441)

                                        10        20        30     
pF1KE0                          MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY
                                    :..:      :::::::::::::::::::::
XP_011 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::...::::
XP_011 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK
               70        80        90       100       110       120

             100       110       120       130       140       150 
pF1KE0 ----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQP
           ::..::::.: ::.:::::..:: ... :::  :           :: :   .: :
XP_011 ALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQVVQASELFQFWSG--GSGPP
              130       140       150       160       170          

             160       170          180             190       200  
pF1KE0 GSSQDVKPFVQQAYPIQPAVTAP---IPGFEPASA------PAPSVPAWQGRSIGTTKLR
        .  ::::: :   :.  ..: :   .::.:: .:      :.:: ::::.:..::..:.
XP_011 WNVPDVKPFSQT--PFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQ
      180       190         200       210       220       230      

            210       220       230       240       250       260  
pF1KE0 LVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELF
       :::::::.:     :::..::::::..   : . : :::::.::::::::::::::.::.
XP_011 LVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELY
        240       250       260       270       280       290      

            270       280                290       300       310   
pF1KE0 GKGPQNAFFLVKFWADLNCNIQ-DDAGA--------FYGVTSQYESSENMTVTCSTKVCS
        .:: .:::::::::::: . . ..:::        ::::.::::: :.::.:::.:   
XP_011 DRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSK---
        300       310       320       330       340       350      

           320       330       340       350       360       370   
pF1KE0 FGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTIL
                 :: :..:.::::::. :::::::..::.:::..:::.:::::::::::::
XP_011 ----------TERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTIL
                     360       370       380       390       400   

           380       390       400       410 
pF1KE0 LVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD
        ::::::::: ::: : :::::.::.::::::::::.:
XP_011 QVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD
           410       420       430       440 

>>XP_011525708 (OMIM: 601729) PREDICTED: transcriptional  (228 aa)
 initn: 657 init1: 512 opt: 687  Z-score: 537.9  bits: 107.6 E(85289): 3.2e-23
Smith-Waterman score: 687; 59.0% identity (71.2% similar) in 212 aa overlap (5-209:30-228)

                                        10        20        30     
pF1KE0                          MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY
                                    :..:      :::::::::::::::::::::
XP_011 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::...::::
XP_011 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK
               70        80        90       100       110       120

             100       110       120       130          140        
pF1KE0 ----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAP---GFWPGMIQT
           ::..::::.: ::.:::::..:: ... :::      :: : :     :: :   .
XP_011 ALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLG------PTGPQASELFQFWSG--GS
              130       140       150             160       170    

      150       160       170       180       190       200        
pF1KE0 GQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSA
       : : .  ::::: :   :.  ..: :   . :.    : .:  :  : ...  : :  . 
XP_011 GPPWNVPDVKPFSQT--PFTLSLTPPSTDL-PGRNSFPEAP--QQISPNVSLARTVSHGH
            180         190       200        210         220       

      210       220       230       240       250       260        
pF1KE0 FLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQN
       :                                                           
XP_011 F                                                           
                                                                   

>>XP_011525707 (OMIM: 601729) PREDICTED: transcriptional  (231 aa)
 initn: 661 init1: 512 opt: 681  Z-score: 533.3  bits: 106.8 E(85289): 5.8e-23
Smith-Waterman score: 681; 58.4% identity (70.8% similar) in 209 aa overlap (5-209:30-231)

                                        10        20        30     
pF1KE0                          MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY
                                    :..:      :::::::::::::::::::::
XP_011 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::...::::
XP_011 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK
               70        80        90       100       110       120

             100       110       120       130       140       150 
pF1KE0 ----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQP
           ::..::::.: ::.:::::..:: ... :::  :           :: :   .: :
XP_011 ALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQVVQASELFQFWSG--GSGPP
              130       140       150       160       170          

             160       170       180       190       200       210 
pF1KE0 GSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLE
        .  ::::: :   :.  ..: :   . :.    : .:  :  : ...  : :  . :  
XP_011 WNVPDVKPFSQT--PFTLSLTPPSTDL-PGRNSFPEAP--QQISPNVSLARTVSHGHF  
      180       190         200        210         220       230   

             220       230       240       250       260       270 
pF1KE0 QQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFF

>>XP_006723492 (OMIM: 601729) PREDICTED: transcriptional  (261 aa)
 initn: 1117 init1: 667 opt: 676  Z-score: 528.9  bits: 106.2 E(85289): 1e-22
Smith-Waterman score: 1107; 68.0% identity (84.6% similar) in 247 aa overlap (174-411:15-261)

           150       160       170       180       190       200   
pF1KE0 GMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRL
                                     :  .. :   :.:: ::::.:..::..:.:
XP_006                 MATSNCKGGWERYEPPQALSPLPPPTPSPPAWQARGLGTARLQL
                               10        20        30        40    

           210       220       230       240       250       260   
pF1KE0 VEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFG
       ::::::.:     :::..::::::..   : . : :::::.::::::::::::::.::. 
XP_006 VEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYD
           50        60        70        80        90       100    

           270       280                290       300       310    
pF1KE0 KGPQNAFFLVKFWADLNCNIQ-DDAGA--------FYGVTSQYESSENMTVTCSTKVCSF
       .:: .:::::::::::: . . ..:::        ::::.::::: :.::.:::.:::::
XP_006 RGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSF
          110       120       130       140       150       160    

          320       330       340       350       360       370    
pF1KE0 GKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILL
       ::::::::::: :..:.::::::. :::::::..::.:::..:::.::::::::::::: 
XP_006 GKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQ
          170       180       190       200       210       220    

          380       390       400       410 
pF1KE0 VVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD
       ::::::::: ::: : :::::.::.::::::::::.:
XP_006 VVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD
          230       240       250       260 




411 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:35:06 2016 done: Sat Nov  5 04:35:08 2016
 Total Scan time:  8.890 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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