Result of FASTA (omim) for pF1KB7668
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7668, 402 aa
  1>>>pF1KB7668 402 - 402 aa - 402 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7848+/-0.000445; mu= 5.9278+/- 0.028
 mean_var=393.9766+/-78.495, 0's: 0 Z-trim(122.7): 295  B-trim: 26 in 1/55
 Lambda= 0.064616
 statistics sampled from 40847 (41212) to 40847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.483), width:  16
 Scan time: 10.060

The best scores are:                                      opt bits E(85289)
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 2808 275.5 1.6e-73
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 2122 211.5 2.9e-54
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390)  608 70.4 8.7e-12
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373)  556 65.5 2.4e-10
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386)  556 65.5 2.5e-10
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397)  556 65.5 2.5e-10
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402)  556 65.6 2.5e-10
NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402)  484 58.8 2.7e-08
NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395)  481 58.5 3.2e-08
NP_001167617 (OMIM: 161200,602575) LIM homeobox tr ( 406)  475 58.0 4.8e-08
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279)  468 57.1 6.1e-08
NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382)  469 57.4 6.8e-08
NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382)  469 57.4 6.8e-08
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534)  453 56.1 2.3e-07
XP_011508408 (OMIM: 262700,602146) PREDICTED: LIM/ ( 329)  444 55.0 3.2e-07
XP_011508407 (OMIM: 262700,602146) PREDICTED: LIM/ ( 329)  444 55.0 3.2e-07
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314)  442 54.8 3.5e-07
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406)  442 54.9 4.1e-07
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363)  437 54.4 5.3e-07
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366)  437 54.4 5.3e-07
NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 377)  437 54.4 5.4e-07
XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobo ( 378)  437 54.4 5.4e-07
NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 392)  437 54.4 5.5e-07
XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobo ( 407)  437 54.5 5.6e-07
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336)  426 53.3   1e-06
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230)  422 52.7 1.1e-06
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378)  426 53.4 1.1e-06
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388)  426 53.4 1.1e-06
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397)  426 53.4 1.1e-06
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403)  426 53.4 1.1e-06
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349)  420 52.8 1.5e-06
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346)  412 52.0 2.6e-06
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356)  412 52.1 2.6e-06
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363)  412 52.1 2.6e-06
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363)  412 52.1 2.6e-06
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359)  409 51.8 3.2e-06
NP_006760 (OMIM: 603129) LIM domain transcription  ( 165)  388 49.3   8e-06
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain  ( 165)  388 49.3   8e-06
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145)  365 47.1 3.3e-05
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145)  365 47.1 3.3e-05
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b  ( 155)  365 47.2 3.4e-05
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156)  365 47.2 3.4e-05
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193)  365 47.3 3.8e-05
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  360 46.6 4.5e-05
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  360 46.6 4.5e-05
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  360 46.6 4.5e-05
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145)  360 46.6 4.5e-05
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  360 46.6 4.5e-05
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145)  360 46.6 4.5e-05
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145)  360 46.6 4.5e-05


>>NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 [Ho  (402 aa)
 initn: 2808 init1: 2808 opt: 2808  Z-score: 1440.8  bits: 275.5 E(85289): 1.6e-73
Smith-Waterman score: 2808; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402)

               10        20        30        40        50        60
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGT
              310       320       330       340       350       360

              370       380       390       400  
pF1KB7 LHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
       ::::::::::::::::::::::::::::::::::::::::::
NP_071 LHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
              370       380       390       400  

>>NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 [Ho  (406 aa)
 initn: 1209 init1: 916 opt: 2122  Z-score: 1095.2  bits: 211.5 E(85289): 2.9e-54
Smith-Waterman score: 2122; 74.6% identity (90.0% similar) in 409 aa overlap (2-402:1-406)

               10        20        30        40        50        60
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRF
        :::::::.:::::::::::::::::.::::::::: ::.:::::::::::::::::: :
NP_005  MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCF
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB7 GTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYL
       ::::::::::::::::::.::::::::::::::.::::::::::::.:::::::::.:::
NP_005 GTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYL
      60        70        80        90       100       110         

               130       140       150       160       170         
pF1KB7 SSSSL-KEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTK
       :.::. ::.::.:... .: ::::: ::  ::: :...... ::::...:::..:: :.:
NP_005 SNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAK
     120       130       140       150       160       170         

     180       190       200       210       220       230         
pF1KB7 RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMK
     180       190       200       210       220       230         

     240       250       260       270       280       290         
pF1KB7 QLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHG
       ::::::::::::::::::::::  ::. .:.. . :...:::::..::.::.::::: .:
NP_005 QLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQG
     240       250       260       270       280       290         

     300        310       320       330        340         350     
pF1KB7 PPS-QAQSPADSSFLAASGPGSTPLGALEPPLAGPH-AADNPRFTDMISHP--DTPSPEP
       ::: :::.:.:  :. .:::..::::.:: :: : : ...  ::::...::  :.:::::
NP_005 PPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEP
     300       310       320       330       340       350         

         360       370          380       390       400  
pF1KB7 GLPGTLHPMPGEVFSGGPSPPFP---MSGTSGYSGPLSHPNPELNEAAVW
       .::: :: : .:::  ::::::    ..: ..:.. :::: ::.::::::
NP_005 SLPGPLHSMSAEVF--GPSPPFSSLSVNGGASYGNHLSHP-PEMNEAAVW
     360       370         380       390        400      

>>NP_203129 (OMIM: 262700,602146) LIM/homeobox protein L  (390 aa)
 initn: 891 init1: 565 opt: 608  Z-score: 332.6  bits: 70.4 E(85289): 8.7e-12
Smith-Waterman score: 836; 37.1% identity (61.0% similar) in 420 aa overlap (4-398:29-384)

                                        10        20        30     
pF1KB7                          MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCEC
                                   .::::.. :::.:.:.:::: :: .:..: .:
NP_203 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADC
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KB7 KTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVC
       . .:...:::: :..:::.:::.::::::..: ::: :...::::.. :.::.::.:..:
NP_203 QMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIIC
               70        80        90       100       110       120

         100       110       120       130       140       150     
pF1KB7 NKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKE
       :.::.::.:.:.......:::.::                                    
NP_203 NRQLATGDEFYLMEDGRLVCKEDY------------------------------------
              130       140                                        

         160       170       180       190       200       210     
pF1KB7 TDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQ
                :::. .:.....:.::  ::::: :::::::: :.  .:::.::.::::..
NP_203 ---------ETAK-QNDDSEAGAKR--PRTTITAKQLETLKNAYKNSPKPARHVREQLSS
                    150         160       170       180       190  

         220       230       240       250       260               
pF1KB7 ETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGR----------L
       ::::.:::.::::::::.::.:.:. .:   :   :..: .: :  . .          .
NP_203 ETGLDMRVVQVWFQNRRAKEKRLKK-DAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGV
            200       210        220       230       240       250 

         270                   280       290       300       310   
pF1KB7 DESEM----------LGSTPYTY--YGDYQGDYYAPGSNYDFFAHGPPSQAQSPADSS-F
       ..::.          :: :   :   ::  :     ::   :   :  .. :.  :.: .
NP_203 SDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGS---FSMDGTGQSYQDLRDGSPY
             260       270       280          290       300        

            320        330        340       350       360       370
pF1KB7 LAASGPGS-TPLGALEPPLAG-PHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFS
          ..:.: . : .  : : :  ...:.     .:.:        :.  ::. :     .
NP_203 GIPQSPSSISSLPSHAPLLNGLDYTVDSN--LGIIAHAG-----QGVSQTLRAM-----A
      310       320       330         340            350           

              380       390       400    
pF1KB7 GGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW  
       :::.  .  ... ::    . :.  :.:      
NP_203 GGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF
        360       370       380       390

>>XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/home  (373 aa)
 initn: 934 init1: 549 opt: 556  Z-score: 306.6  bits: 65.5 E(85289): 2.4e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:7-367)

                 10        20        30        40        50        
pF1KB7   MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFR
             ::::.. :::::.:..::: :: ::..: .:.: :.:.::::  ..:::.:::.
XP_016 MQQIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFK
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB7 RFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDD
       :::::::.:  :: :...::.:.. :.::.::.:.::..::.::.:.:.......::: :
XP_016 RFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB7 YLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGT
       :                                             :::.... :   .:
XP_016 Y---------------------------------------------ETAKQREAE---AT
                                                           130     

      180       190       200       210       220       230        
pF1KB7 KRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRM
        .: ::::: ::::::::.:. ..:::.::.::::..::::.:::.::::::::.::.:.
XP_016 AKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL
             140       150       160       170       180       190 

      240       250       260          270       280       290     
pF1KB7 KQLSALGARRHAFFRSPRRMRPLGGRLDES---EMLGSTPYTYYGDYQGDYYAPGSNYDF
       :. .:   :   .::. .: :  :.. :..   :   :   . . :  .      .:  .
XP_016 KK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLY
              200       210        220       230       240         

         300          310                   320       330       340
pF1KB7 FAHGPPSQA---QSPADSSFLAASG------------PGSTPLGALEPPLAGPHAADNPR
        . : :.::    : : ..:    :            ::: : : . :  :.:..  .:.
XP_016 GSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGS-PYG-VPPSPAAPQSLPGPQ
     250       260       270       280        290        300       

               350            360       370        380       390   
pF1KB7 -FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFSG-GPSPPFPMSGTSGYSGPLSHPN
        . . . .:::     ::  :: :    : : .:..: :::  .  ....::    . : 
XP_016 PLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLAGNGPSSDLSTGSSGGYPDFPASPA
       310       320       330            340       350       360  

           400    
pF1KB7 PELNEAAVW  
         :.:      
XP_016 SWLDEVDHAQF
            370   

>>XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/home  (386 aa)
 initn: 934 init1: 549 opt: 556  Z-score: 306.4  bits: 65.5 E(85289): 2.5e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:20-380)

                              10        20        30        40     
pF1KB7                MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFS
                          ::::.. :::::.:..::: :: ::..: .:.: :.:.:::
XP_005 MTLNMKETRWGAPAPEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFS
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB7 REGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEEL
       :  ..:::.:::.:::::::.:  :: :...::.:.. :.::.::.:.::..::.::.:.
XP_005 RGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEF
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB7 YVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKE
       :.......::: ::                                             :
XP_005 YLMEDSRLVCKADY---------------------------------------------E
              130                                                  

         170       180       190       200       210       220     
pF1KB7 TANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQ
       ::.... :   .: .: ::::: ::::::::.:. ..:::.::.::::..::::.:::.:
XP_005 TAKQREAE---ATAKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQ
         140           150       160       170       180       190 

         230       240       250       260          270       280  
pF1KB7 VWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDES---EMLGSTPYTYYGDY
       :::::::.::.:.:. .:   :   .::. .: :  :.. :..   :   :   . . : 
XP_005 VWFQNRRAKEKRLKK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQDSDAEVSFPDE
             200        210       220        230       240         

            290       300          310                   320       
pF1KB7 QGDYYAPGSNYDFFAHGPPSQA---QSPADSSFLAASG------------PGSTPLGALE
        .      .:  . . : :.::    : : ..:    :            ::: : : . 
XP_005 PSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGS-PYG-VP
     250       260       270       280       290       300         

       330       340        350            360       370        380
pF1KB7 PPLAGPHAADNPR-FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFSG-GPSPPFPMS
       :  :.:..  .:. . . . .:::     ::  :: :    : : .:..: :::  .  .
XP_005 PSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLAGNGPSSDLSTG
       310       320       330       340            350       360  

              390       400    
pF1KB7 GTSGYSGPLSHPNPELNEAAVW  
       ...::    . :   :.:      
XP_005 SSGGYPDFPASPASWLDEVDHAQF
            370       380      

>>NP_835258 (OMIM: 221750,600577) LIM/homeobox protein L  (397 aa)
 initn: 934 init1: 549 opt: 556  Z-score: 306.3  bits: 65.5 E(85289): 2.5e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:31-391)

                                         10        20        30    
pF1KB7                           MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
                                     ::::.. :::::.:..::: :: ::..: .
NP_835 MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
       :.: :.:.::::  ..:::.:::.:::::::.:  :: :...::.:.. :.::.::.:.:
NP_835 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV
               70        80        90       100       110       120

          100       110       120       130       140       150    
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
       :..::.::.:.:.......::: ::                                   
NP_835 CKRQLATGDEFYLMEDSRLVCKADY-----------------------------------
              130       140                                        

          160       170       180       190       200       210    
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLA
                 :::.... :   .: .: ::::: ::::::::.:. ..:::.::.::::.
NP_835 ----------ETAKQREAE---ATAKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLS
                   150           160       170       180       190 

          220       230       240       250       260          270 
pF1KB7 QETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDES---EML
       .::::.:::.::::::::.::.:.:. .:   :   .::. .: :  :.. :..   :  
NP_835 SETGLDMRVVQVWFQNRRAKEKRLKK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQ
             200       210        220       230        240         

             280       290       300          310                  
pF1KB7 GSTPYTYYGDYQGDYYAPGSNYDFFAHGPPSQA---QSPADSSFLAASG-----------
        :   . . :  .      .:  . . : :.::    : : ..:    :           
NP_835 DSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYREL
     250       260       270       280       290       300         

        320       330       340        350            360       370
pF1KB7 -PGSTPLGALEPPLAGPHAADNPR-FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFS
        ::: : : . :  :.:..  .:. . . . .:::     ::  :: :    : : .:..
NP_835 RPGS-PYG-VPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLA
     310         320       330       340       350            360  

               380       390       400    
pF1KB7 G-GPSPPFPMSGTSGYSGPLSHPNPELNEAAVW  
       : :::  .  ....::    . :   :.:      
NP_835 GNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
            370       380       390       

>>NP_055379 (OMIM: 221750,600577) LIM/homeobox protein L  (402 aa)
 initn: 934 init1: 549 opt: 556  Z-score: 306.3  bits: 65.6 E(85289): 2.5e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:36-396)

                                         10        20        30    
pF1KB7                           MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
                                     ::::.. :::::.:..::: :: ::..: .
NP_055 ELGPARESAGGDLLLALLARRADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD
          10        20        30        40        50        60     

           40        50        60        70        80        90    
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
       :.: :.:.::::  ..:::.:::.:::::::.:  :: :...::.:.. :.::.::.:.:
NP_055 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV
          70        80        90       100       110       120     

          100       110       120       130       140       150    
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
       :..::.::.:.:.......::: ::                                   
NP_055 CKRQLATGDEFYLMEDSRLVCKADY-----------------------------------
         130       140       150                                   

          160       170       180       190       200       210    
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLA
                 :::.... :   .: .: ::::: ::::::::.:. ..:::.::.::::.
NP_055 ----------ETAKQREAE---ATAKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLS
                           160        170       180       190      

          220       230       240       250       260          270 
pF1KB7 QETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDES---EML
       .::::.:::.::::::::.::.:.:. .:   :   .::. .: :  :.. :..   :  
NP_055 SETGLDMRVVQVWFQNRRAKEKRLKK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQ
        200       210       220        230       240        250    

             280       290       300          310                  
pF1KB7 GSTPYTYYGDYQGDYYAPGSNYDFFAHGPPSQA---QSPADSSFLAASG-----------
        :   . . :  .      .:  . . : :.::    : : ..:    :           
NP_055 DSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYREL
          260       270       280       290       300       310    

        320       330       340        350            360       370
pF1KB7 -PGSTPLGALEPPLAGPHAADNPR-FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFS
        ::: : : . :  :.:..  .:. . . . .:::     ::  :: :    : : .:..
NP_055 RPGS-PYG-VPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLA
           320        330       340       350       360            

               380       390       400    
pF1KB7 G-GPSPPFPMSGTSGYSGPLSHPNPELNEAAVW  
       : :::  .  ....::    . :   :.:      
NP_055 GNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
       370       380       390       400  

>>NP_001167618 (OMIM: 161200,602575) LIM homeobox transc  (402 aa)
 initn: 616 init1: 400 opt: 484  Z-score: 270.0  bits: 58.8 E(85289): 2.7e-08
Smith-Waterman score: 695; 37.4% identity (65.5% similar) in 313 aa overlap (5-309:56-345)

                                         10        20        30    
pF1KB7                           MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
                                     : ::.::: ::::. : . .:: .:.::  
NP_001 DGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAA
          30        40        50        60        70        80     

           40        50        60        70        80        90    
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
       :.  :. .:. :. :::::.:. . :..::.:: . :.:...: .:   :.::.:: : :
NP_001 CQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCV
          90       100       110       120       130       140     

          100       110       120       130       140       150    
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
       :..::  :.: .:. :....:: ::      :: .: :       :.::: .:..... .
NP_001 CERQLRKGDE-FVLKEGQLLCKGDYE-----KEKDLLS-------SVSPDESDSVKSEDE
         150        160       170                   180       190  

          160       170       180        190       200       210   
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKR-RGPRTTIKAKQLETLKAAFAATPKPTRHIREQL
       . : . .. . . .. . ....  .: . ::: . ..: ...::.: .. :: :..:: :
NP_001 DGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETL
            200       210       220       230       240       250  

           220       230       240       250       260       270   
pF1KB7 AQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGS
       : ::::..::.::::::.:.:   ::.:    ::::   .  .  . :: ..  :.: : 
NP_001 AAETGLSVRVVQVWFQNQRAK---MKKL----ARRHQQQQEQQNSQRLGQEVLSSRMEGM
            260       270              280       290       300     

            280           290         300       310       320      
pF1KB7 -TPYTYYGDYQGDYYA----PGSNYDFFAHG--PPSQAQSPADSSFLAASGPGSTPLGAL
        . ::  .  : .  :    : .. : : .:  ::   : :.:                 
NP_001 MASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPP---QMPGDHMNPYGNDSIFHDIDSD
         310       320       330       340          350       360  

        330       340       350       360       370       380      
pF1KB7 EPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGPSPPFPMSGTSGYS
                                                                   
NP_001 TSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS                    
            370       380       390       400                      

>>NP_002307 (OMIM: 161200,602575) LIM homeobox transcrip  (395 aa)
 initn: 616 init1: 400 opt: 481  Z-score: 268.6  bits: 58.5 E(85289): 3.2e-08
Smith-Waterman score: 700; 35.3% identity (64.5% similar) in 346 aa overlap (5-333:56-381)

                                         10        20        30    
pF1KB7                           MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
                                     : ::.::: ::::. : . .:: .:.::  
NP_002 DGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAA
          30        40        50        60        70        80     

           40        50        60        70        80        90    
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
       :.  :. .:. :. :::::.:. . :..::.:: . :.:...: .:   :.::.:: : :
NP_002 CQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCV
          90       100       110       120       130       140     

          100       110       120       130       140       150    
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
       :..::  :.: .:. :....:: ::      :: .: :       :.::: .:..... .
NP_002 CERQLRKGDE-FVLKEGQLLCKGDYE-----KEKDLLS-------SVSPDESDSVKSEDE
         150        160       170                   180       190  

          160       170       180        190       200       210   
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKR-RGPRTTIKAKQLETLKAAFAATPKPTRHIREQL
       . : . .. . . .. . ....  .: . ::: . ..: ...::.: .. :: :..:: :
NP_002 DGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETL
            200       210       220       230       240       250  

           220       230       240       250       260       270   
pF1KB7 AQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGS
       : ::::..::.::::::.:.:   ::.:    ::::   .  .  . :: ..  :.: : 
NP_002 AAETGLSVRVVQVWFQNQRAK---MKKL----ARRHQQQQEQQNSQRLGQEVLSSRMEGM
            260       270              280       290       300     

            280           290         300              310         
pF1KB7 -TPYTYYGDYQGDYYA----PGSNYDFFAHG--PPSQAQSPA-------DSSFLAASGP-
        . ::  .  : .  :    : .. : : .:  ::..  . .       :.:. . :   
NP_002 MASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCF
         310       320       330       340       350       360     

       320       330       340       350       360       370       
pF1KB7 -GSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGPSPPF
        ::. .:.:.  ...:                                            
NP_002 LGSSDVGSLQARVGNPIDRLYSMQSSYFAS                              
         370       380       390                                   

>>NP_001167617 (OMIM: 161200,602575) LIM homeobox transc  (406 aa)
 initn: 616 init1: 400 opt: 475  Z-score: 265.4  bits: 58.0 E(85289): 4.8e-08
Smith-Waterman score: 680; 34.0% identity (63.1% similar) in 350 aa overlap (5-333:56-392)

                                         10        20        30    
pF1KB7                           MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
                                     : ::.::: ::::. : . .:: .:.::  
NP_001 DGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAA
          30        40        50        60        70        80     

           40        50        60        70        80        90    
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
       :.  :. .:. :. :::::.:. . :..::.:: . :.:...: .:   :.::.:: : :
NP_001 CQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCV
          90       100       110       120       130       140     

          100       110       120       130       140       150    
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
       :..::  :.: .:. :....:: ::      :: .: :       :.::: .:..... .
NP_001 CERQLRKGDE-FVLKEGQLLCKGDYE-----KEKDLLS-------SVSPDESDSVKSEDE
         150        160       170                   180       190  

          160       170       180        190       200       210   
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKR-RGPRTTIKAKQLETLKAAFAATPKPTRHIREQL
       . : . .. . . .. . ....  .: . ::: . ..: ...::.: .. :: :..:: :
NP_001 DGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETL
            200       210       220       230       240       250  

           220       230           240       250       260         
pF1KB7 AQETGLNMRVIQVWFQNRRSK----ERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESE
       : ::::..::.::::::.:.:     :: .: .     ..     :   . :: ..  :.
NP_001 AAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQGEPGPGQGLGQEVLSSR
            260       270       280       290       300       310  

     270        280           290         300              310     
pF1KB7 MLGS-TPYTYYGDYQGDYYA----PGSNYDFFAHG--PPSQAQSPA-------DSSFLAA
       : :  . ::  .  : .  :    : .. : : .:  ::..  . .       :.:. . 
NP_001 MEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSL
            320       330       340       350       360       370  

           320       330       340       350       360       370   
pF1KB7 SGP--GSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGP
       :    ::. .:.:.  ...:                                        
NP_001 SDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS                          
            380       390       400                                




402 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:05:35 2016 done: Sat Nov  5 04:05:36 2016
 Total Scan time: 10.060 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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