Result of FASTA (omim) for pF1KB6343
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6343, 264 aa
  1>>>pF1KB6343 264 - 264 aa - 264 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2972+/-0.000339; mu= 3.3792+/- 0.021
 mean_var=181.8356+/-36.582, 0's: 0 Z-trim(121.5): 5  B-trim: 410 in 1/59
 Lambda= 0.095112
 statistics sampled from 38314 (38319) to 38314 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.449), width:  16
 Scan time:  7.860

The best scores are:                                      opt bits E(85289)
NP_057683 (OMIM: 605602,613838) myozenin-2 [Homo s ( 264) 1789 256.7 3.1e-68
XP_006714297 (OMIM: 605602,613838) PREDICTED: myoz ( 195) 1276 186.3 3.7e-47
NP_067068 (OMIM: 605603) myozenin-1 [Homo sapiens] ( 299)  305 53.2 6.7e-07
NP_001116325 (OMIM: 610735) myozenin-3 [Homo sapie ( 251)  265 47.6 2.6e-05
NP_588612 (OMIM: 610735) myozenin-3 [Homo sapiens] ( 251)  265 47.6 2.6e-05


>>NP_057683 (OMIM: 605602,613838) myozenin-2 [Homo sapie  (264 aa)
 initn: 1789 init1: 1789 opt: 1789  Z-score: 1346.1  bits: 256.7 E(85289): 3.1e-68
Smith-Waterman score: 1789; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264)

               10        20        30        40        50        60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 DYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWI
              190       200       210       220       230       240

              250       260    
pF1KB6 SENIPIVITTEPTDDTTVPESEDL
       ::::::::::::::::::::::::
NP_057 SENIPIVITTEPTDDTTVPESEDL
              250       260    

>>XP_006714297 (OMIM: 605602,613838) PREDICTED: myozenin  (195 aa)
 initn: 1276 init1: 1276 opt: 1276  Z-score: 967.5  bits: 186.3 E(85289): 3.7e-47
Smith-Waterman score: 1276; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)

               10        20        30        40        50        60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 DYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWI
       :::::::                                                     
XP_006 DYRSFNRGSRLHWRK                                             
              190                                                  

>>NP_067068 (OMIM: 605603) myozenin-1 [Homo sapiens]      (299 aa)
 initn: 524 init1: 271 opt: 305  Z-score: 244.8  bits: 53.2 E(85289): 6.7e-07
Smith-Waterman score: 470; 35.2% identity (58.2% similar) in 287 aa overlap (9-257:11-296)

                 10        20        30        40        50        
pF1KB6   MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLF
                 :.::..   .     :.. .:..::::.:.:::.:::::: :.:::...:
NP_067 MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMF
               10        20        30        40        50        60

       60        70         80              90             100     
pF1KB6 KMRQRRSDKYTFENF-QYQSRAQINH------SIAMQNGKV-DG-----SNLEGGSQQAP
       :.:: : .:. .::  .  : ....:      ... : : . .:     :: .:::: . 
NP_067 KLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGG
               70        80        90       100       110       120

         110         120       130       140                       
pF1KB6 LTPPNT--PDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTA-------------------V
           .    : .   .  . : : .::  .        ::                   :
NP_067 SGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITV
              130       140       150       160       170       180

          150       160       170       180       190       200    
pF1KB6 PKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKF
        : : ::::.:.. ::.    :   :.   .::::: :.::::.: :.::.::::. . :
NP_067 FKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTF
              190       200       210       220       230       240

          210        220       230       240       250          260
pF1KB6 KVPDFELL-LLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTE---PTDDTTVPE
       ..: :.:  ::..: .. . . ::.: ::::::  :.: . :.  ...   : :  :   
NP_067 QMPKFDLGPLLSEP-LVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
              250        260       270       280       290         

           
pF1KB6 SEDL

>>NP_001116325 (OMIM: 610735) myozenin-3 [Homo sapiens]   (251 aa)
 initn: 449 init1: 184 opt: 265  Z-score: 216.3  bits: 47.6 E(85289): 2.6e-05
Smith-Waterman score: 436; 34.1% identity (58.3% similar) in 264 aa overlap (9-245:4-246)

               10        20        30        40        50        60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
               :..:  . : : ..  . :  .:::::.:.:.:.:.::::  .:::. ::. 
NP_001      MIPKEQKGPVMAAMGDLT-EPVPTLDLGKKLSVPQDLMMEELSLRNNRGSLLFQK
                    10         20        30        40        50    

               70        80                     90       100       
pF1KB6 RQRRSDKYTFENFQYQSRAQINHS-------------IAMQNGKVDGSNLEGGSQQAPLT
       :::: .:.::: .  ..::..  :             .:  ::  .: : ..  .  : .
NP_001 RQRRVQKFTFE-LAASQRAMLAGSARRKVTGTAESGTVANANGP-EGPNYRSELHIFPAS
           60         70        80        90        100       110  

       110                  120       130       140       150      
pF1KB6 PPNT---PDPRSP--------PNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAI
       :  .   :.   :        :.:. .::::. ::: .:::::: ::. : :. ::.. .
NP_001 PGASLGGPEGAHPAAAPAGCVPSPSALAPGYAEPLKGVPPEKFNHTAISKGYRCPWQEFV
            120       130       140       150       160       170  

        160       170       180          190       200       210   
pF1KB6 SNDPELLEALYPKLFKPEGKAELP---DYRSFNRVATPFGGFEKASRMVKFKVPDFELLL
       :           . .. .:... :   :::.::.. .::::   ..    :  :   .. 
NP_001 SY----------RDYQSDGRSHTPSPNDYRNFNKTPVPFGGPLVGG---TFPRPGTPFI-
                      180       190       200          210         

           220       230       240       250       260    
pF1KB6 LTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
          :. .: .. :  : ::::. .::. .:.:                   
NP_001 ---PEPLSGLELLRLRPSFNRVAQGWV-RNLPESEEL              
         220       230       240        250               

>>NP_588612 (OMIM: 610735) myozenin-3 [Homo sapiens]      (251 aa)
 initn: 449 init1: 184 opt: 265  Z-score: 216.3  bits: 47.6 E(85289): 2.6e-05
Smith-Waterman score: 436; 34.1% identity (58.3% similar) in 264 aa overlap (9-245:4-246)

               10        20        30        40        50        60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
               :..:  . : : ..  . :  .:::::.:.:.:.:.::::  .:::. ::. 
NP_588      MIPKEQKGPVMAAMGDLT-EPVPTLDLGKKLSVPQDLMMEELSLRNNRGSLLFQK
                    10         20        30        40        50    

               70        80                     90       100       
pF1KB6 RQRRSDKYTFENFQYQSRAQINHS-------------IAMQNGKVDGSNLEGGSQQAPLT
       :::: .:.::: .  ..::..  :             .:  ::  .: : ..  .  : .
NP_588 RQRRVQKFTFE-LAASQRAMLAGSARRKVTGTAESGTVANANGP-EGPNYRSELHIFPAS
           60         70        80        90        100       110  

       110                  120       130       140       150      
pF1KB6 PPNT---PDPRSP--------PNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAI
       :  .   :.   :        :.:. .::::. ::: .:::::: ::. : :. ::.. .
NP_588 PGASLGGPEGAHPAAAPAGCVPSPSALAPGYAEPLKGVPPEKFNHTAISKGYRCPWQEFV
            120       130       140       150       160       170  

        160       170       180          190       200       210   
pF1KB6 SNDPELLEALYPKLFKPEGKAELP---DYRSFNRVATPFGGFEKASRMVKFKVPDFELLL
       :           . .. .:... :   :::.::.. .::::   ..    :  :   .. 
NP_588 SY----------RDYQSDGRSHTPSPNDYRNFNKTPVPFGGPLVGG---TFPRPGTPFI-
                      180       190       200          210         

           220       230       240       250       260    
pF1KB6 LTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
          :. .: .. :  : ::::. .::. .:.:                   
NP_588 ---PEPLSGLELLRLRPSFNRVAQGWV-RNLPESEEL              
         220       230       240        250               




264 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:00:31 2016 done: Sat Nov  5 04:00:32 2016
 Total Scan time:  7.860 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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