Result of FASTA (omim) for pF1KE0795
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0795, 358 aa
  1>>>pF1KE0795 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2023+/-0.000349; mu= 3.2883+/- 0.022
 mean_var=184.1567+/-37.899, 0's: 0 Z-trim(121.1): 206  B-trim: 1729 in 2/55
 Lambda= 0.094511
 statistics sampled from 36841 (37197) to 36841 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.436), width:  16
 Scan time:  9.860

The best scores are:                                      opt bits E(85289)
NP_004243 (OMIM: 604990,612287) Na(+)/H(+) exchang ( 358) 2370 335.1 1.4e-91
NP_001123484 (OMIM: 606553) Na(+)/H(+) exchange re ( 337)  999 148.2 2.6e-35
NP_004776 (OMIM: 606553) Na(+)/H(+) exchange regul ( 326)  998 148.0 2.8e-35
XP_016879384 (OMIM: 606553) PREDICTED: Na(+)/H(+)  ( 281)  668 103.0 8.6e-22
NP_001239004 (OMIM: 606553) Na(+)/H(+) exchange re ( 224)  611 95.1 1.6e-19
XP_016879383 (OMIM: 606553) PREDICTED: Na(+)/H(+)  ( 372)  610 95.2 2.6e-19
NP_001239002 (OMIM: 606553) Na(+)/H(+) exchange re ( 226)  598 93.4 5.4e-19
NP_001239005 (OMIM: 606553) Na(+)/H(+) exchange re ( 215)  597 93.2 5.7e-19
XP_005255759 (OMIM: 606553) PREDICTED: Na(+)/H(+)  ( 342)  594 92.9 1.1e-18
XP_006721044 (OMIM: 606553) PREDICTED: Na(+)/H(+)  ( 202)  568 89.2 8.5e-18
NP_001188255 (OMIM: 603831) Na(+)/H(+) exchange re ( 408)  482 77.7   5e-14
NP_079067 (OMIM: 607146) Na(+)/H(+) exchange regul ( 491)  426 70.2 1.1e-11
NP_001161940 (OMIM: 607146) Na(+)/H(+) exchange re ( 505)  426 70.2 1.2e-11
XP_011541307 (OMIM: 607146) PREDICTED: Na(+)/H(+)  ( 506)  426 70.2 1.2e-11
XP_016873823 (OMIM: 607146) PREDICTED: Na(+)/H(+)  ( 557)  426 70.2 1.3e-11
XP_011541302 (OMIM: 607146) PREDICTED: Na(+)/H(+)  ( 571)  426 70.2 1.3e-11
XP_011541304 (OMIM: 607146) PREDICTED: Na(+)/H(+)  ( 571)  426 70.2 1.3e-11
XP_011541303 (OMIM: 607146) PREDICTED: Na(+)/H(+)  ( 571)  426 70.2 1.3e-11
XP_016856956 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 312)  313 54.6 3.5e-07
XP_011507920 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 508)  313 54.8 5.1e-07
XP_011507918 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 512)  313 54.8 5.1e-07
NP_001188254 (OMIM: 603831) Na(+)/H(+) exchange re ( 519)  313 54.8 5.2e-07
NP_002605 (OMIM: 603831) Na(+)/H(+) exchange regul ( 519)  313 54.8 5.2e-07
XP_016856953 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 519)  313 54.8 5.2e-07
XP_011507921 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 409)  302 53.2 1.2e-06
XP_016856954 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 409)  302 53.2 1.2e-06
XP_016856955 (OMIM: 603831) PREDICTED: Na(+)/H(+)  ( 409)  302 53.2 1.2e-06
XP_005265623 (OMIM: 602625) PREDICTED: membrane-as (1479)  270 49.2 6.8e-05
XP_005265622 (OMIM: 602625) PREDICTED: membrane-as (1481)  270 49.2 6.8e-05
XP_011516796 (OMIM: 607084,607928,611383) PREDICTE ( 556)  259 47.4   9e-05
XP_011516793 (OMIM: 607084,607928,611383) PREDICTE ( 571)  259 47.4 9.1e-05
XP_011516794 (OMIM: 607084,607928,611383) PREDICTE ( 571)  259 47.4 9.1e-05
XP_011516791 (OMIM: 607084,607928,611383) PREDICTE ( 577)  259 47.4 9.2e-05
XP_011516790 (OMIM: 607084,607928,611383) PREDICTE ( 837)  259 47.6 0.00012
NP_001166896 (OMIM: 607084,607928,611383) whirlin  ( 906)  259 47.6 0.00013
NP_056219 (OMIM: 607084,607928,611383) whirlin iso ( 907)  259 47.6 0.00013
XP_011516788 (OMIM: 607084,607928,611383) PREDICTE ( 917)  259 47.6 0.00013
XP_011516787 (OMIM: 607084,607928,611383) PREDICTE ( 918)  259 47.6 0.00013
XP_011516786 (OMIM: 607084,607928,611383) PREDICTE ( 918)  259 47.6 0.00013
XP_005265625 (OMIM: 602625) PREDICTED: membrane-as (1478)  260 47.9 0.00017
XP_006713473 (OMIM: 602625) PREDICTED: membrane-as (1479)  260 47.9 0.00017
XP_011532538 (OMIM: 602625) PREDICTED: membrane-as (1480)  260 47.9 0.00017
XP_016862987 (OMIM: 602625) PREDICTED: membrane-as (1490)  260 47.9 0.00017
XP_016862986 (OMIM: 602625) PREDICTED: membrane-as (1491)  260 47.9 0.00018
XP_005265621 (OMIM: 602625) PREDICTED: membrane-as (1491)  260 47.9 0.00018
XP_006713472 (OMIM: 602625) PREDICTED: membrane-as (1492)  260 47.9 0.00018
XP_006713471 (OMIM: 602625) PREDICTED: membrane-as (1492)  260 47.9 0.00018
XP_005265620 (OMIM: 602625) PREDICTED: membrane-as (1492)  260 47.9 0.00018
XP_006713470 (OMIM: 602625) PREDICTED: membrane-as (1493)  260 47.9 0.00018
XP_011510811 (OMIM: 601014) PREDICTED: disks large ( 554)  242 45.1 0.00045


>>NP_004243 (OMIM: 604990,612287) Na(+)/H(+) exchange re  (358 aa)
 initn: 2370 init1: 2370 opt: 2370  Z-score: 1764.9  bits: 335.1 E(85289): 1.4e-91
Smith-Waterman score: 2370; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)

               10        20        30        40        50        60
pF1KE0 MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 EPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 KCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQ
              250       260       270       280       290       300

              310       320       330       340       350        
pF1KE0 DSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
              310       320       330       340       350        

>>NP_001123484 (OMIM: 606553) Na(+)/H(+) exchange regula  (337 aa)
 initn: 1083 init1: 966 opt: 999  Z-score: 755.0  bits: 148.2 E(85289): 2.6e-35
Smith-Waterman score: 1104; 52.1% identity (72.0% similar) in 361 aa overlap (6-358:2-337)

               10         20        30        40        50         
pF1KE0 MSADAAAGAPL-PRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRL
            ::  :: :::: : .: .:::::::::::. ::.:: :::::::: :.: :::::
NP_001     MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRL
                   10        20        30        40        50      

      60        70        80        90       100       110         
pF1KE0 VEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEA-PG
       ::::: ::: :::.:::.::.:. . .:::::: ::::.:..  .   ::.  ::.. : 
NP_001 VEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEM--AQRGLPP
         60        70        80        90       100         110    

      120         130       140       150       160       170      
pF1KE0 QAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPG
         .:  :    .. ... .:  . : : :  :::::::: ..:::.:::::::::::.::
NP_001 AHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKGPQGYGFNLHSDKSRPG
          120       130       140        150       160       170   

        180       190       200       210       220       230      
pF1KE0 QFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETD
       :.:::::: :::  ::::::::..::::  .:: .:..::..:.:  ::..::::: :::
NP_001 QYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETD
           180       190       200       210       220       230   

        240       250       260       270       280       290      
pF1KE0 EFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEE
       : ::. :: :..::..:::: : :::                    :: . ..:. .:. 
NP_001 EHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGSACSSR-
           240       250       260                         270     

        300       310       320           330       340       350  
pF1KE0 LNSQDSPPKQDSTAPSSTSSSDPILDFNISL----AMAKERAHQKRSSKRAPQMDWSKKN
          .: : .. .:  .:. ..::. . .. :    : :::.:.  : .::::::::..: 
NP_001 ---SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKR
             280       290       300       310       320       330 

             
pF1KE0 ELFSNL
       :.:::.
NP_001 EIFSNF
             

>>NP_004776 (OMIM: 606553) Na(+)/H(+) exchange regulator  (326 aa)
 initn: 1083 init1: 966 opt: 998  Z-score: 754.5  bits: 148.0 E(85289): 2.8e-35
Smith-Waterman score: 1084; 52.1% identity (71.1% similar) in 357 aa overlap (6-358:2-326)

               10         20        30        40        50         
pF1KE0 MSADAAAGAPL-PRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRL
            ::  :: :::: : .: .:::::::::::. ::.:: :::::::: :.: :::::
NP_004     MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRL
                   10        20        30        40        50      

      60        70        80        90       100       110         
pF1KE0 VEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEA-PG
       ::::: ::: :::.:::.::.:. . .:::::: ::::.:..  .   ::.  ::.. : 
NP_004 VEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEM--AQRGLPP
         60        70        80        90       100         110    

      120         130       140       150       160       170      
pF1KE0 QAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPG
         .:  :    .. ... .:  . : : :  :::::::: ..:::.:::::::::::.::
NP_004 AHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKGPQGYGFNLHSDKSRPG
          120       130       140        150       160       170   

        180       190       200       210       220       230      
pF1KE0 QFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETD
       :.:::::: :::  ::::::::..::::  .:: .:..::..:.:  ::..::::: :::
NP_004 QYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETD
           180       190       200       210       220       230   

        240       250       260       270       280       290      
pF1KE0 EFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEE
       : ::. :: :..::..:::: : :::                    :: . ..:. .:. 
NP_004 EHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGSACSSR-
           240       250       260                         270     

        300       310       320       330       340       350      
pF1KE0 LNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFS
          .: : .. .:  :.       : .. . : :::.:.  : .::::::::..: :.::
NP_004 ---SDLPGSDKDTEESG-------LHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFS
             280              290       300       310       320    

         
pF1KE0 NL
       :.
NP_004 NF
         

>>XP_016879384 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch  (281 aa)
 initn: 762 init1: 645 opt: 668  Z-score: 512.2  bits: 103.0 E(85289): 8.6e-22
Smith-Waterman score: 773; 46.6% identity (69.5% similar) in 292 aa overlap (74-358:15-281)

            50        60        70        80        90       100   
pF1KE0 PGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLG
                                     .::.::.:. . .:::::: ::::.:..  
XP_016                 MDACAHRDRQTENLKVVQRIKAVEGQTRLLVVDQETDEELRRRQ
                               10        20        30        40    

           110        120         130       140       150       160
pF1KE0 VQVREELLRAQEA-PGQAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKG
       .   ::.  ::.. :   .:  :    .. ... .:  . : : :  :::::::: ..::
XP_016 LTCTEEM--AQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKG
           50          60        70        80         90       100 

              170       180       190       200       210       220
pF1KE0 PSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIR
       :.:::::::::::.:::.:::::: :::  ::::::::..::::  .:: .:..::..:.
XP_016 PQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIK
             110       120       130       140       150       160 

              230       240       250       260       270       280
pF1KE0 AGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALES
       :  ::..::::: :::: ::. :: :..::..:::: : :::                  
XP_016 AREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT-----------------
             170       180       190       200                     

              290       300       310       320           330      
pF1KE0 PRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL----AMAKERAHQ
         :: . ..:. .:.    .: : .. .:  .:. ..::. . .. :    : :::.:. 
XP_016 -SPAQLNGGSACSSR----SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARA
           210           220       230       240       250         

        340       350        
pF1KE0 KRSSKRAPQMDWSKKNELFSNL
        : .::::::::..: :.:::.
XP_016 MRVNKRAPQMDWNRKREIFSNF
     260       270       280 

>>NP_001239004 (OMIM: 606553) Na(+)/H(+) exchange regula  (224 aa)
 initn: 677 init1: 560 opt: 611  Z-score: 471.6  bits: 95.1 E(85289): 1.6e-19
Smith-Waterman score: 716; 49.4% identity (70.2% similar) in 245 aa overlap (118-358:5-224)

        90       100       110       120       130       140       
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQ
                                     :.: ::: :   ::  .. :.. : : :  
NP_001                           MARSGSATPPARA--PGAPPRSPPQRLDVSGP-L
                                         10          20        30  

       150       160       170       180       190       200       
pF1KE0 RELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCM
       :::::::: ..:::.:::::::::::.:::.:::::: :::  ::::::::..::::  .
NP_001 RELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNV
              40        50        60        70        80        90 

       210       220       230       240       250       260       
pF1KE0 EGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKE
       :: .:..::..:.:  ::..::::: :::: ::. :: :..::..:::: : :::     
NP_001 EGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT----
             100       110       120       130       140           

       270       280       290       300       310       320       
pF1KE0 NSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL
                      :: . ..:. .:.    .: : .. .:  .:. ..::. . .. :
NP_001 --------------SPAQLNGGSACSSR----SDLPGSDKDTEDGSAWKQDPFQESGLHL
                     150       160           170       180         

           330       340       350        
pF1KE0 ----AMAKERAHQKRSSKRAPQMDWSKKNELFSNL
           : :::.:.  : .::::::::..: :.:::.
NP_001 SPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
     190       200       210       220    

>>XP_016879383 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch  (372 aa)
 initn: 677 init1: 560 opt: 610  Z-score: 467.8  bits: 95.2 E(85289): 2.6e-19
Smith-Waterman score: 696; 49.4% identity (68.9% similar) in 241 aa overlap (118-358:164-372)

        90       100       110       120       130       140       
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQ
                                     :.: ::: :   ::  .. :.. : : :  
XP_016 GGSLGRPESSGHPGRTPATCCHCAAVMARSGSATPPARA--PGAPPRSPPQRLDVSGP-L
           140       150       160       170         180        190

       150       160       170       180       190       200       
pF1KE0 RELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCM
       :::::::: ..:::.:::::::::::.:::.:::::: :::  ::::::::..::::  .
XP_016 RELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNV
              200       210       220       230       240       250

       210       220       230       240       250       260       
pF1KE0 EGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKE
       :: .:..::..:.:  ::..::::: :::: ::. :: :..::..:::: : :::     
XP_016 EGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT----
              260       270       280       290       300          

       270       280       290       300       310       320       
pF1KE0 NSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL
                      :: . ..:. .:.    .: : .. .:  :.       : .. . 
XP_016 --------------SPAQLNGGSACSSR----SDLPGSDKDTEESG-------LHLSPTA
                      310       320           330              340 

       330       340       350        
pF1KE0 AMAKERAHQKRSSKRAPQMDWSKKNELFSNL
       : :::.:.  : .::::::::..: :.:::.
XP_016 AEAKEKARAMRVNKRAPQMDWNRKREIFSNF
             350       360       370  

>>NP_001239002 (OMIM: 606553) Na(+)/H(+) exchange regula  (226 aa)
 initn: 677 init1: 560 opt: 598  Z-score: 461.9  bits: 93.4 E(85289): 5.4e-19
Smith-Waterman score: 703; 49.0% identity (69.6% similar) in 247 aa overlap (118-358:5-226)

        90       100       110       120       130         140     
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE--ADKSHP
                                     :.: ::: :   ::  .. :..   : : :
NP_001                           MARSGSATPPARA--PGAPPRSPPQRLVQDVSGP
                                         10          20        30  

         150       160       170       180       190       200     
pF1KE0 EQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGV
         :::::::: ..:::.:::::::::::.:::.:::::: :::  ::::::::..:::: 
NP_001 -LRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQ
              40        50        60        70        80        90 

         210       220       230       240       250       260     
pF1KE0 CMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQ
        .:: .:..::..:.:  ::..::::: :::: ::. :: :..::..:::: : :::   
NP_001 NVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT--
             100       110       120       130       140           

         270       280       290       300       310       320     
pF1KE0 KENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNI
                        :: . ..:. .:.    .: : .. .:  .:. ..::. . ..
NP_001 ----------------SPAQLNGGSACSSR----SDLPGSDKDTEDGSAWKQDPFQESGL
                     150       160           170       180         

             330       340       350        
pF1KE0 SL----AMAKERAHQKRSSKRAPQMDWSKKNELFSNL
        :    : :::.:.  : .::::::::..: :.:::.
NP_001 HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
     190       200       210       220      

>>NP_001239005 (OMIM: 606553) Na(+)/H(+) exchange regula  (215 aa)
 initn: 677 init1: 560 opt: 597  Z-score: 461.5  bits: 93.2 E(85289): 5.7e-19
Smith-Waterman score: 683; 49.0% identity (68.3% similar) in 243 aa overlap (118-358:5-215)

        90       100       110       120       130         140     
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE--ADKSHP
                                     :.: ::: :   ::  .. :..   : : :
NP_001                           MARSGSATPPARA--PGAPPRSPPQRLVQDVSGP
                                         10          20        30  

         150       160       170       180       190       200     
pF1KE0 EQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGV
         :::::::: ..:::.:::::::::::.:::.:::::: :::  ::::::::..:::: 
NP_001 -LRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQ
              40        50        60        70        80        90 

         210       220       230       240       250       260     
pF1KE0 CMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQ
        .:: .:..::..:.:  ::..::::: :::: ::. :: :..::..:::: : :::   
NP_001 NVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT--
             100       110       120       130       140           

         270       280       290       300       310       320     
pF1KE0 KENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNI
                        :: . ..:. .:.    .: : .. .:  :.       : .. 
NP_001 ----------------SPAQLNGGSACSSR----SDLPGSDKDTEESG-------LHLSP
                     150       160           170              180  

         330       340       350        
pF1KE0 SLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
       . : :::.:.  : .::::::::..: :.:::.
NP_001 TAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
            190       200       210     

>>XP_005255759 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch  (342 aa)
 initn: 560 init1: 560 opt: 594  Z-score: 456.5  bits: 92.9 E(85289): 1.1e-18
Smith-Waterman score: 594; 61.9% identity (79.6% similar) in 147 aa overlap (118-262:164-307)

        90       100       110       120       130         140     
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE--ADKSHP
                                     :.: ::: :   ::  .. :..   : : :
XP_005 GGSLGRPESSGHPGRTPATCCHCAAVMARSGSATPPARA--PGAPPRSPPQRLVQDVSGP
           140       150       160       170         180       190 

         150       160       170       180       190       200     
pF1KE0 EQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGV
         :::::::: ..:::.:::::::::::.:::.:::::: :::  ::::::::..:::: 
XP_005 -LRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQ
              200       210       220       230       240       250

         210       220       230       240       250       260     
pF1KE0 CMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQ
        .:: .:..::..:.:  ::..::::: :::: ::. :: :..::..:::: : :::   
XP_005 NVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSP
              260       270       280       290       300       310

         270       280       290       300       310       320     
pF1KE0 KENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNI
                                                                   
XP_005 AQLNGGSACSSRSDLPGSDKDTEEGPPSGVWD                            
              320       330       340                              

>>XP_006721044 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch  (202 aa)
 initn: 677 init1: 560 opt: 568  Z-score: 440.5  bits: 89.2 E(85289): 8.5e-18
Smith-Waterman score: 673; 50.5% identity (71.2% similar) in 222 aa overlap (141-358:4-202)

              120       130       140       150       160       170
pF1KE0 LRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHS
                                     : : :  :::::::: ..:::.::::::::
XP_006                            MPEDVSGP-LRELRPRLCHLRKGPQGYGFNLHS
                                           10        20        30  

              180       190       200       210       220       230
pF1KE0 DKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLV
       :::.:::.:::::: :::  ::::::::..::::  .:: .:..::..:.:  ::..:::
XP_006 DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLV
             40        50        60        70        80        90  

              240       250       260       270       280       290
pF1KE0 VDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSAS
       :: :::: ::. :: :..::..:::: : :::                    :: . ..:
XP_006 VDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGS
            100       110       120                         130    

              300       310       320           330       340      
pF1KE0 SDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL----AMAKERAHQKRSSKRAPQM
       . .:.    .: : .. .:  .:. ..::. . .. :    : :::.:.  : .::::::
XP_006 ACSSR----SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQM
              140       150       160       170       180       190

        350        
pF1KE0 DWSKKNELFSNL
       ::..: :.:::.
XP_006 DWNRKREIFSNF
              200  




358 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:11:53 2016 done: Sat Nov  5 03:11:54 2016
 Total Scan time:  9.860 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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