Result of FASTA (omim) for pF1KE0757
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0757, 330 aa
  1>>>pF1KE0757 330 - 330 aa - 330 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.3107+/-0.000361; mu= -6.0766+/- 0.023
 mean_var=320.6572+/-66.399, 0's: 0 Z-trim(123.9): 86  B-trim: 33 in 1/55
 Lambda= 0.071623
 statistics sampled from 44475 (44572) to 44475 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.523), width:  16
 Scan time:  9.430

The best scores are:                                      opt bits E(85289)
NP_003678 (OMIM: 166710,603422) PDZ and LIM domain ( 330) 2312 251.9 1.4e-66
NP_001124499 (OMIM: 166710,603422) PDZ and LIM dom ( 246) 1570 175.1 1.4e-43
XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ  ( 252) 1561 174.1 2.7e-43
NP_066272 (OMIM: 605900) PDZ and LIM domain protei ( 329)  906 106.6 7.7e-23
NP_001244892 (OMIM: 605889) PDZ and LIM domain pro ( 197)  545 69.1 8.9e-12
NP_001244891 (OMIM: 605889) PDZ and LIM domain pro ( 276)  545 69.2 1.1e-11
NP_001107579 (OMIM: 605889) PDZ and LIM domain pro ( 316)  536 68.3 2.4e-11
NP_055291 (OMIM: 605889) PDZ and LIM domain protei ( 364)  536 68.4 2.7e-11
XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM ( 226)  517 66.2 7.3e-11
NP_976227 (OMIM: 605903) PDZ and LIM domain protei ( 423)  428 57.3 6.9e-08
NP_001073584 (OMIM: 605906,609452) LIM domain-bind ( 330)  386 52.8 1.2e-06
XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM  ( 330)  386 52.8 1.2e-06
XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM  ( 330)  386 52.8 1.2e-06
XP_011537497 (OMIM: 605906,609452) PREDICTED: LIM  ( 398)  383 52.6 1.6e-06
NP_001165082 (OMIM: 605906,609452) LIM domain-bind ( 398)  383 52.6 1.6e-06
XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM  ( 664)  386 53.1 1.9e-06
XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM  ( 727)  386 53.1 2.1e-06
NP_009009 (OMIM: 605906,609452) LIM domain-binding ( 727)  386 53.1 2.1e-06
XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM  ( 743)  386 53.1 2.1e-06
XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM  ( 743)  386 53.1 2.1e-06
NP_001165081 (OMIM: 605906,609452) LIM domain-bind ( 732)  383 52.8 2.6e-06
XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM  ( 748)  383 52.8 2.6e-06
XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM  ( 795)  383 52.9 2.7e-06
XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM  ( 811)  383 52.9 2.8e-06
XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM  ( 811)  383 52.9 2.8e-06
NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596)  359 50.3 1.2e-05
XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607)  358 50.2 1.3e-05
XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728)  359 50.3 1.4e-05
NP_932159 (OMIM: 609722) PDZ and LIM domain protei ( 278)  348 48.8 1.5e-05
XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739)  358 50.2 1.6e-05
NP_789847 (OMIM: 609722) PDZ and LIM domain protei ( 366)  349 49.1 1.8e-05
NP_998801 (OMIM: 605903) PDZ and LIM domain protei ( 222)  342 48.1   2e-05
XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602)  351 49.4 2.2e-05
NP_067643 (OMIM: 609722) PDZ and LIM domain protei ( 602)  349 49.2 2.5e-05
XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734)  351 49.5 2.6e-05
NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457)  342 48.4 3.4e-05
XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498)  336 47.8 5.6e-05
XP_006714131 (OMIM: 605904) PREDICTED: PDZ and LIM ( 630)  337 48.0 6.2e-05
XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM  ( 283)  326 46.6 7.6e-05
NP_001073585 (OMIM: 605906,609452) LIM domain-bind ( 283)  326 46.6 7.6e-05
NP_001011515 (OMIM: 605904) PDZ and LIM domain pro ( 234)  323 46.2 8.2e-05
XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493)  327 46.9 0.00011
NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617)  326 46.9 0.00013
XP_011537493 (OMIM: 605906,609452) PREDICTED: LIM  ( 633)  326 46.9 0.00014
NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483)  323 46.5 0.00014
XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM  ( 680)  326 46.9 0.00014
XP_011537491 (OMIM: 605906,609452) PREDICTED: LIM  ( 696)  326 46.9 0.00015
NP_001243355 (OMIM: 605904) PDZ and LIM domain pro ( 625)  323 46.6 0.00017
NP_001011516 (OMIM: 605904) PDZ and LIM domain pro ( 214)  307 44.5 0.00024
NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487)  313 45.4 0.00029


>>NP_003678 (OMIM: 166710,603422) PDZ and LIM domain pro  (330 aa)
 initn: 2312 init1: 2312 opt: 2312  Z-score: 1316.2  bits: 251.9 E(85289): 1.4e-66
Smith-Waterman score: 2312; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330)

               10        20        30        40        50        60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_003 KLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
              250       260       270       280       290       300

              310       320       330
pF1KE0 YCESHAKARVKPPEGYDVVAVYPNAKVELV
       ::::::::::::::::::::::::::::::
NP_003 YCESHAKARVKPPEGYDVVAVYPNAKVELV
              310       320       330

>>NP_001124499 (OMIM: 166710,603422) PDZ and LIM domain   (246 aa)
 initn: 1570 init1: 1570 opt: 1570  Z-score: 903.5  bits: 175.1 E(85289): 1.4e-43
Smith-Waterman score: 1570; 95.0% identity (96.2% similar) in 240 aa overlap (1-240:1-240)

               10        20        30        40        50        60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
       ::::::::::::::::::::::::::::::::::::::::::::   .  :  .  :.::
NP_001 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
                                                                   
NP_001 CAVTAA                                                      
                                                                   

>>XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ and   (252 aa)
 initn: 1561 init1: 1561 opt: 1561  Z-score: 898.3  bits: 174.1 E(85289): 2.7e-43
Smith-Waterman score: 1615; 76.1% identity (76.1% similar) in 330 aa overlap (1-330:1-252)

               10        20        30        40        50        60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
       :::::::::::::::::::::::::::::::                             
XP_016 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISR-----------------------------
               10        20        30                              

               70        80        90       100       110       120
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
                                                        :::::::::::
XP_016 -------------------------------------------------DGSPTTSRRPS
                                                               40  

              130       140       150       160       170       180
pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
             50        60        70        80        90       100  

              190       200       210       220       230       240
pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
            110       120       130       140       150       160  

              250       260       270       280       290       300
pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 KLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
            170       180       190       200       210       220  

              310       320       330
pF1KE0 YCESHAKARVKPPEGYDVVAVYPNAKVELV
       ::::::::::::::::::::::::::::::
XP_016 YCESHAKARVKPPEGYDVVAVYPNAKVELV
            230       240       250  

>>NP_066272 (OMIM: 605900) PDZ and LIM domain protein 1   (329 aa)
 initn: 924 init1: 474 opt: 906  Z-score: 531.0  bits: 106.6 E(85289): 7.7e-23
Smith-Waterman score: 906; 44.6% identity (67.5% similar) in 332 aa overlap (3-323:4-328)

                10        20        30        40        50         
pF1KE0  MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL
          ... :.::.:::::::::.::  ::.::::  ::::::: :: ::.: ::.::.:  
NP_066 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
               10        20        30        40        50        60

      60        70        80         90       100       110        
pF1KE0 MTHLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQD----GSP-
       ::::::::::::: :.:::.:.: : . : : . ...: . .....  : :.    ::  
NP_066 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
               70        80        90       100       110       120

           120       130       140       150            160        
pF1KE0 TTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSS-----EATLPAQMSTLHVSPPP
       . :  :  .. .       . . :..:  .   .: :.     :.   :.    .  :  
NP_066 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
              130       140       150       160       170       180

      170       180       190       200       210       220        
pF1KE0 SADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPG
        :.:  .:       .:  ::::.::.:  : .   :::: ::  :: .::. : ::   
NP_066 HAQPPSSL------VIDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNK
                    190       200        210       220       230   

      230       240       250       260       270       280        
pF1KE0 PGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNL
       :.: :..:  ..:..: ... : :: : .:  ::::..:: ::.  ::::..:.::: ::
NP_066 PSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNL
           240       250       260       270       280       290   

      290       300       310       320       330
pF1KE0 KQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
       ::.:.::.....:::.::. :: :::::.::.:.:       
NP_066 KQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK      
           300       310       320               

>>NP_001244892 (OMIM: 605889) PDZ and LIM domain protein  (197 aa)
 initn: 606 init1: 363 opt: 545  Z-score: 332.4  bits: 69.1 E(85289): 8.9e-12
Smith-Waterman score: 550; 43.6% identity (67.6% similar) in 204 aa overlap (123-325:9-197)

            100       110       120       130       140       150  
pF1KE0 DDSKAQAHRIHIDPEIQDGSPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSE
                                     : .:   : : :  ..::  . . ..:.  
NP_001                       MPQTVILPGPAPWGFRLSGGIDFNQP--LVITRDGNYF
                                     10        20          30      

            160       170       180       190        200       210 
pF1KE0 ATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSF
                  : :  :..:. ..:   :        :::::..   ::.  .:.:::::
NP_001 EHKHNIRPKPFVIPGRSSEPTASVPPESD--------VYRMLHDNRNEPT--QPRQSGSF
         40        50        60                70          80      

             220       230       240       250       260       270 
pF1KE0 RYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARD
       : ::::..  .:.:   :.: :...  ..:. .  .: : .: : .:  ::::..:::::
NP_001 RVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARD
         90          100       110       120       130       140   

             280       290       300       310       320       330
pF1KE0 KLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
       :  :::::.:.::.:::::.::::.. .::::.::.::.:::::::.:..::.:     
NP_001 KYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA     
           150       160       170       180       190            

>>NP_001244891 (OMIM: 605889) PDZ and LIM domain protein  (276 aa)
 initn: 827 init1: 363 opt: 545  Z-score: 330.4  bits: 69.2 E(85289): 1.1e-11
Smith-Waterman score: 869; 45.0% identity (66.7% similar) in 327 aa overlap (1-325:1-276)

               10        20        30        40        50        60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
       ::..: : ::.:::::: :: ::. ::.:.:.  ::::: : :::::.: ::.: .:: :
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
               10        20        30        40        50        60

               70        80         90       100       110         
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP
       :: .::.:::.   .: :...: : . : :.. .:.::.  .:... : :::.    .. 
NP_001 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKH-
               70        80        90       100       110          

     120       130       140       150       160       170         
pF1KE0 SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRS
               . ::.   :.  : :       ::: :         .: :: .:        
NP_001 --------NIRPK---PFVIPGR-------SSEPT---------ASVPPESD--------
             120          130                       140            

     180       190        200       210       220       230        
pF1KE0 RDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPT
                 :::::..   ::.  .:.:::::: ::::..  .:.:   :.: :...  
NP_001 ----------VYRMLHDNRNEPT--QPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAP
                    150         160       170          180         

      240       250       260       270       280       290        
pF1KE0 ASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDE
       ..:. .  .: : .: : .:  ::::..::::::  :::::.:.::.:::::.::::.. 
NP_001 VTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEG
     190       200       210       220       230       240         

      300       310       320       330
pF1KE0 RLYCESHAKARVKPPEGYDVVAVYPNAKVELV
       .::::.::.::.:::::::.:..::.:     
NP_001 ELYCETHARARTKPPEGYDTVTLYPKA     
     250       260       270           

>>NP_001107579 (OMIM: 605889) PDZ and LIM domain protein  (316 aa)
 initn: 796 init1: 363 opt: 536  Z-score: 324.6  bits: 68.3 E(85289): 2.4e-11
Smith-Waterman score: 923; 44.3% identity (71.7% similar) in 332 aa overlap (1-325:1-316)

               10        20        30        40        50        60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
       ::..: : ::.:::::: :: ::. ::.:.:.  ::::: : :::::.: ::.: .:: :
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
               10        20        30        40        50        60

               70        80         90       100       110         
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTS---
       :: .::.:::.   .: :...: : . : :.. .:.::.  .:... : :. .:  .   
NP_001 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
               70        80        90       100       110       120

          120       130       140       150       160       170    
pF1KE0 RR--PSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR
       ::  :  .... .: :  ... :..:  . .  ... . .: .:.  : .   :. .:. 
NP_001 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA
              130       140         150       160        170       

          180       190        200       210       220       230   
pF1KE0 GLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPR
       ..:   :        :::::..   ::  ..:.:::::: ::::..  .:.:   :.: :
NP_001 SVPPESD--------VYRMLHDNRNEP--TQPRQSGSFRVLQGMVD--DGSD-DRPAGTR
       180               190         200       210          220    

           240       250       260       270       280       290   
pF1KE0 NLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGY
       ...  ..:. .  .: : .: : .:  ::::..::::::  :::::.:.::.:::::.::
NP_001 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY
          230       240       250       260       270       280    

           300       310       320       330
pF1KE0 FFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
       ::.. .::::.::.::.:::::::.:..::.:     
NP_001 FFIEGELYCETHARARTKPPEGYDTVTLYPKA     
          290       300       310           

>>NP_055291 (OMIM: 605889) PDZ and LIM domain protein 3   (364 aa)
 initn: 849 init1: 363 opt: 536  Z-score: 323.8  bits: 68.4 E(85289): 2.7e-11
Smith-Waterman score: 842; 42.3% identity (62.9% similar) in 364 aa overlap (9-325:9-364)

               10        20        30        40        50        60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
               ::.:::::: :: ::. ::.:.:.  ::::: : :::::.: ::.: .:: :
NP_055 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
               10        20        30        40        50        60

               70        80         90       100       110         
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGS-------
       :: .::.:::.   .: :...: : . : :.. .:.::.  .:... : :::.       
NP_055 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN
               70        80        90       100       110       120

                       120       130         140                   
pF1KE0 --------PTTSR---RPSGTGTGPEDGRPSLGSPYGQ--P----------PRFPVPHN-
               :  :     :::   :   . ::  :  .   :          : .:.  . 
NP_055 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL
              130       140       150       160       170       180

           150              160         170       180       190    
pF1KE0 -G----SSEATLPAQ-------MSTLH--VSPPPSADPARGLPRSRDCRVDLGSEVYRML
        :     .. . : :       : ::.  ::   .  :  . : .    :   :.:::::
NP_055 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTAS---VPPESDVYRML
              190       200       210       220          230       

           200       210       220       230       240       250   
pF1KE0 REP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLP
       ..   ::  ..:.:::::: ::::..  .:.:   :.: :...  ..:. .  .: : .:
NP_055 HDNRNEP--TQPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHGGSGGAQRMP
       240         250       260          270       280       290  

           260       270       280       290       300       310   
pF1KE0 ECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPP
        : .:  ::::..::::::  :::::.:.::.:::::.::::.. .::::.::.::.:::
NP_055 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPP
            300       310       320       330       340       350  

           320       330
pF1KE0 EGYDVVAVYPNAKVELV
       ::::.:..::.:     
NP_055 EGYDTVTLYPKA     
            360         

>>XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM dom  (226 aa)
 initn: 537 init1: 474 opt: 517  Z-score: 316.0  bits: 66.2 E(85289): 7.3e-11
Smith-Waterman score: 517; 44.9% identity (68.8% similar) in 176 aa overlap (148-323:57-225)

       120       130       140       150       160       170       
pF1KE0 RPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLP
                                     :.. :.   :.    .  :   :.:  .: 
XP_011 SPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLV
         30        40        50        60        70        80      

       180       190       200       210       220       230       
pF1KE0 RSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKP
             .:  ::::.::.:  : .   :::: ::  :: .::. : ::   :.: :..: 
XP_011 ------IDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKA
               90       100        110       120       130         

       240       250       260       270       280       290       
pF1KE0 TASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLD
        ..:..: ... : :: : .:  ::::..:: ::.  ::::..:.::: ::::.:.::..
XP_011 PVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVE
     140       150       160       170       180       190         

       300       310       320       330
pF1KE0 ERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
       ...:::.::. :: :::::.::.:.:       
XP_011 DQIYCEKHARERVTPPEGYEVVTVFPK      
     200       210       220            

>>NP_976227 (OMIM: 605903) PDZ and LIM domain protein 7   (423 aa)
 initn: 481 init1: 289 opt: 428  Z-score: 262.6  bits: 57.3 E(85289): 6.9e-08
Smith-Waterman score: 455; 33.0% identity (52.4% similar) in 336 aa overlap (5-312:6-305)

                10        20        30        40        50         
pF1KE0  MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL
            :.:.::.:::::: ::.::..::.:::.  :.::: :..  :: . .:.::..  
NP_976 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
               10        20        30        40        50        60

      60        70        80        90        100       110        
pF1KE0 MTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQA-HRIHIDPEIQDGSP-----
       .::.::::.:..: ..:.:..:: .    :     .:.:.  .  . : . :.:      
NP_976 LTHIEAQNKIRACGERLSLGLSRAQ----PVQSKPQKVQTPDKQPLRPLVPDASKQRLME
               70        80            90       100       110      

            120                      130       140         150     
pF1KE0 -TTSRRPS-GTG-----------TGPE---DGRPSLGSPYGQPPRF--PVPHNGSSEATL
        : . ::  :::           :: :   :      .  .: ::   :.: ... .   
NP_976 NTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPW
        120       130       140       150       160       170      

         160       170           180       190       200       210 
pF1KE0 PAQMSTLHVSPPPSA-DPA---RGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSF
       :.  .   .: :: : :::   :  :       :  : :     .:: :.   : :: . 
NP_976 PGPTAPSPTSRPPWAVDPAFAERYAP-------DKTSTVLTRHSQPATPT---PLQSRT-
        180       190       200              210          220      

             220       230       240       250       260       270 
pF1KE0 RYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARD
           ....:. ::  :: ::  : :                : : .: . : :  . :  
NP_976 ----SIVQAAAGG-VPG-GGSNNGKT---------------PVCHQCHKVIRGRYLVALG
             230         240                      250       260    

             280       290       300       310       320       330 
pF1KE0 KLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV 
       . :::: :.::.::  :.. :.:     ..:     .:  :                   
NP_976 HAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKM
          270       280       290       300       310       320    

NP_976 TWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALG
          330       340       350       360       370       380    




330 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:04:18 2016 done: Sat Nov  5 03:04:19 2016
 Total Scan time:  9.430 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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