Result of FASTA (omim) for pF1KE0733
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0733, 311 aa
  1>>>pF1KE0733 311 - 311 aa - 311 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.6922+/-0.000361; mu= -3.5489+/- 0.022
 mean_var=533.7074+/-118.743, 0's: 0 Z-trim(124.0): 806  B-trim: 33 in 1/58
 Lambda= 0.055517
 statistics sampled from 43548 (44906) to 43548 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.527), width:  16
 Scan time:  8.820

The best scores are:                                      opt bits E(85289)
NP_006866 (OMIM: 300295) serine/threonine-protein  ( 311) 2214 191.5 1.9e-48
NP_001001852 (OMIM: 610580) serine/threonine-prote ( 326) 1197 110.1 6.4e-24
NP_002639 (OMIM: 164960) serine/threonine-protein  ( 313) 1146 105.9 1.1e-22
NP_001230115 (OMIM: 164960) serine/threonine-prote ( 404) 1146 106.1 1.2e-22
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765)  486 53.7 1.4e-06
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765)  486 53.7 1.4e-06
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765)  486 53.7 1.4e-06
XP_005247048 (OMIM: 607505) PREDICTED: PAS domain- (1107)  483 53.7   2e-06
XP_011509134 (OMIM: 607505) PREDICTED: PAS domain- (1137)  483 53.7 2.1e-06
NP_001239051 (OMIM: 607505) PAS domain-containing  (1288)  483 53.8 2.2e-06
XP_016859124 (OMIM: 607505) PREDICTED: PAS domain- (1323)  483 53.8 2.2e-06
NP_001239049 (OMIM: 607505) PAS domain-containing  (1323)  483 53.8 2.2e-06
XP_016859125 (OMIM: 607505) PREDICTED: PAS domain- (1323)  483 53.8 2.2e-06
NP_055963 (OMIM: 607505) PAS domain-containing ser (1323)  483 53.8 2.2e-06
XP_016859123 (OMIM: 607505) PREDICTED: PAS domain- (1414)  483 53.8 2.3e-06
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709)  461 51.6 5.4e-06
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719)  461 51.6 5.5e-06
NP_004945 (OMIM: 600526) serine/threonine-protein  ( 724)  461 51.6 5.5e-06
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729)  461 51.6 5.5e-06
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738)  461 51.6 5.6e-06
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739)  461 51.6 5.6e-06
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744)  461 51.7 5.6e-06
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745)  461 51.7 5.6e-06
NP_059672 (OMIM: 600526) serine/threonine-protein  ( 745)  461 51.7 5.6e-06
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753)  461 51.7 5.6e-06
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763)  461 51.7 5.7e-06
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784)  461 51.7 5.7e-06
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788)  461 51.7 5.7e-06
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793)  461 51.7 5.8e-06
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798)  461 51.7 5.8e-06
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799)  461 51.7 5.8e-06
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808)  461 51.7 5.8e-06
XP_006723370 (OMIM: 606495) PREDICTED: MAP/microtu ( 685)  458 51.4 6.3e-06
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688)  458 51.4 6.3e-06
NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752)  458 51.4 6.6e-06
NP_006242 (OMIM: 602739) 5'-AMP-activated protein  ( 559)  453 50.8 7.5e-06
XP_011509137 (OMIM: 607505) PREDICTED: PAS domain- ( 873)  457 51.4 7.6e-06
XP_011509136 (OMIM: 607505) PREDICTED: PAS domain- ( 944)  457 51.5 7.9e-06
XP_011509135 (OMIM: 607505) PREDICTED: PAS domain- (1114)  457 51.6 8.6e-06
XP_011509133 (OMIM: 607505) PREDICTED: PAS domain- (1144)  457 51.6 8.8e-06
XP_011509130 (OMIM: 607505) PREDICTED: PAS domain- (1330)  457 51.7 9.5e-06
XP_011509132 (OMIM: 607505) PREDICTED: PAS domain- (1330)  457 51.7 9.5e-06
NP_001239048 (OMIM: 607505) PAS domain-containing  (1330)  457 51.7 9.5e-06
XP_011509131 (OMIM: 607505) PREDICTED: PAS domain- (1330)  457 51.7 9.5e-06
XP_011509128 (OMIM: 607505) PREDICTED: PAS domain- (1355)  457 51.7 9.6e-06
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734)  450 50.8   1e-05
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783)  450 50.8 1.1e-05
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661)  448 50.5 1.1e-05
XP_016856796 (OMIM: 606511) PREDICTED: serine/thre ( 670)  448 50.5 1.1e-05
XP_016856795 (OMIM: 606511) PREDICTED: serine/thre ( 685)  448 50.6 1.1e-05


>>NP_006866 (OMIM: 300295) serine/threonine-protein kina  (311 aa)
 initn: 2214 init1: 2214 opt: 2214  Z-score: 990.8  bits: 191.5 E(85289): 1.9e-48
Smith-Waterman score: 2214; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)

               10        20        30        40        50        60
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
              250       260       270       280       290       300

              310 
pF1KE0 GPAPLAWSLLP
       :::::::::::
NP_006 GPAPLAWSLLP
              310 

>>NP_001001852 (OMIM: 610580) serine/threonine-protein k  (326 aa)
 initn: 1013 init1: 1013 opt: 1197  Z-score: 550.4  bits: 110.1 E(85289): 6.4e-24
Smith-Waterman score: 1197; 61.9% identity (78.0% similar) in 291 aa overlap (6-294:12-301)

                     10          20        30        40        50  
pF1KE0       MLTKPLQGPPAPPGTPTP--PPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRL
                  : :: .    :.    :.  :.:.::  :..: .::.::::::.:: :.
NP_001 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KE0 TDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGF
       .: : ::.: . ..::  :. :. . : ::::.:: ::::.::  ::::::::::  .::
NP_001 ADGLPVAVKHVVKERVTEWGSLGGA-TVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGF
               70        80         90       100       110         

            120       130       140       150       160       170  
pF1KE0 MLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILID
       .:::::: :::::::.:::.: : :  .: ::.::.::..:::: :::::::::::.:.:
NP_001 LLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVD
     120       130       140       150       160       170         

            180       190       200       210       220       230  
pF1KE0 LRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMV
       :: :  :::::::::::.:  ::::::::::::::::  :.::.  :::::::.::::::
NP_001 LRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
     180       190       200       210       220       230         

            240       250       260       270       280       290  
pF1KE0 CGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAED
       :::::::.:.:::...: :  .:::.:  ::: ::. .:: ::::..:   :::      
NP_001 CGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGG
     240       250       260       270       280       290         

            300       310         
pF1KE0 VPLNPSKGGPAPLAWSLLP        
       ::                         
NP_001 VPESCDLRLCTLDPDDVASTTSSSESL
     300       310       320      

>>NP_002639 (OMIM: 164960) serine/threonine-protein kina  (313 aa)
 initn: 907 init1: 907 opt: 1146  Z-score: 528.5  bits: 105.9 E(85289): 1.1e-22
Smith-Waterman score: 1146; 56.3% identity (77.2% similar) in 302 aa overlap (6-304:12-311)

                     10        20        30        40        50    
pF1KE0       MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTD
                  :.. :      :    ::..: .:..:..:::::.::::.:..: :..:
NP_002 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KE0 RLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFML
        : :::: . ..:.  :. : ...  :.::.:: ::..  :  ::::::::::  ..:.:
NP_002 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--GFSGVIRLLDWFERPDSFVL
               70        80        90         100       110        

          120       130       140       150       160       170    
pF1KE0 VLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLR
       .:::: :.:::::.:::.: : :  .: :: ::. :..:::. ::.::::::::::::: 
NP_002 ILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLN
      120       130       140       150       160       170        

          180       190       200       210       220       230    
pF1KE0 RGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCG
       ::  :::::::::::.:  ::::::::::::::::  :.::.  :.::::::::::::::
NP_002 RGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
      180       190       200       210       220       230        

          240       250       260       270       280          290 
pF1KE0 DIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQT---PAE
       :::::.:.::..... :  .:: .:  ::: ::: .::.::..:::   ::::    : :
NP_002 DIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQE
      240       250       260       270       280       290        

             300       310 
pF1KE0 DVPLNPSKGGPAPLAWSLLP
        . ..  . .:.:       
NP_002 TAEIHLHSLSPGPSK     
      300       310        

>>NP_001230115 (OMIM: 164960) serine/threonine-protein k  (404 aa)
 initn: 1143 init1: 907 opt: 1146  Z-score: 527.4  bits: 106.1 E(85289): 1.2e-22
Smith-Waterman score: 1146; 56.3% identity (77.2% similar) in 302 aa overlap (6-304:103-402)

                                        10        20        30     
pF1KE0                          MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLG
                                     :.. :      :    ::..: .:..:..:
NP_001 GSCGSSSGHRPCADILEVGMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVG
             80        90       100       110       120       130  

          40        50        60        70        80        90     
pF1KE0 PLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGG
       ::::.::::.:..: :..: : :::: . ..:.  :. : ...  :.::.:: ::..  :
NP_001 PLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--G
            140       150       160       170       180         190

         100       110       120       130       140       150     
pF1KE0 HPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCH
         ::::::::::  ..:.:.:::: :.:::::.:::.: : :  .: :: ::. :..:::
NP_001 FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCH
              200       210       220       230       240       250

         160       170       180       190       200       210     
pF1KE0 SRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYH
       . ::.::::::::::::: ::  :::::::::::.:  ::::::::::::::::  :.::
NP_001 NCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYH
              260       270       280       290       300       310

         220       230       240       250       260       270     
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
       .  :.:::::::::::::::::::.:.::..... :  .:: .:  ::: ::: .::.::
NP_001 GRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRP
              320       330       340       350       360       370

         280          290       300       310 
pF1KE0 SLEEILLDPWMQT---PAEDVPLNPSKGGPAPLAWSLLP
       ..:::   ::::    : : . ..  . .:.:       
NP_001 TFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK     
              380       390       400         

>>XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ser  (765 aa)
 initn: 461 init1: 203 opt: 486  Z-score: 239.1  bits: 53.7 E(85289): 1.4e-06
Smith-Waterman score: 507; 36.9% identity (62.4% similar) in 282 aa overlap (32-295:16-284)

              10        20        30        40         50        60
pF1KE0 LTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAI
                                     : :   ::.: :..: .: : .: . .::.
XP_005                MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGE-KVAV
                              10        20        30        40     

                 70        80        90       100       110        
pF1KE0 KVIPRNRV--LGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLER
       ::: ....  :. . : . : :   . :.        ::...:: . ..::  ..:.:: 
XP_005 KVIDKTKLDTLATGHLFQEVRC---MKLVQ-------HPNIVRLYEVIDTQTKLYLILEL
           50        60           70               80        90    

      120       130         140       150       160       170      
pF1KE0 PLPAQDLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRG
          . :.::::   :.: :.:  .. .:.:.: ::..::.  :::::.: ::...  ..:
XP_005 G-DGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG
           100       110        120       130       140       150  

        180        190       200       210       220       230     
pF1KE0 CAKLIDFG-SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGD
        .:: ::: :. .   .  :   :. .:: :: .   .: :  . .::::..:. .:::.
XP_005 LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQ
            160       170       180       190       200       210  

         240             250       260       270       280         
pF1KE0 IPFER--DQE----ILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ--
        ::..  :.:    :.. .   :.::: .:  :: : :   :. : :::::   ::.:  
XP_005 PPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGV
            220       230       240       250       260       270  

         290         300       310                                 
pF1KE0 --TPAE--DVPLNPSKGGPAPLAWSLLP                                
         .::   ..::                                                
XP_005 DPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLL
            280       290       300       310       320       330  

>>NP_060189 (OMIM: 612760) SNF-related serine/threonine-  (765 aa)
 initn: 461 init1: 203 opt: 486  Z-score: 239.1  bits: 53.7 E(85289): 1.4e-06
Smith-Waterman score: 507; 36.9% identity (62.4% similar) in 282 aa overlap (32-295:16-284)

              10        20        30        40         50        60
pF1KE0 LTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAI
                                     : :   ::.: :..: .: : .: . .::.
NP_060                MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGE-KVAV
                              10        20        30        40     

                 70        80        90       100       110        
pF1KE0 KVIPRNRV--LGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLER
       ::: ....  :. . : . : :   . :.        ::...:: . ..::  ..:.:: 
NP_060 KVIDKTKLDTLATGHLFQEVRC---MKLVQ-------HPNIVRLYEVIDTQTKLYLILEL
           50        60           70               80        90    

      120       130         140       150       160       170      
pF1KE0 PLPAQDLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRG
          . :.::::   :.: :.:  .. .:.:.: ::..::.  :::::.: ::...  ..:
NP_060 G-DGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG
           100       110        120       130       140       150  

        180        190       200       210       220       230     
pF1KE0 CAKLIDFG-SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGD
        .:: ::: :. .   .  :   :. .:: :: .   .: :  . .::::..:. .:::.
NP_060 LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQ
            160       170       180       190       200       210  

         240             250       260       270       280         
pF1KE0 IPFER--DQE----ILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ--
        ::..  :.:    :.. .   :.::: .:  :: : :   :. : :::::   ::.:  
NP_060 PPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGV
            220       230       240       250       260       270  

         290         300       310                                 
pF1KE0 --TPAE--DVPLNPSKGGPAPLAWSLLP                                
         .::   ..::                                                
NP_060 DPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLL
            280       290       300       310       320       330  

>>NP_001094064 (OMIM: 612760) SNF-related serine/threoni  (765 aa)
 initn: 461 init1: 203 opt: 486  Z-score: 239.1  bits: 53.7 E(85289): 1.4e-06
Smith-Waterman score: 507; 36.9% identity (62.4% similar) in 282 aa overlap (32-295:16-284)

              10        20        30        40         50        60
pF1KE0 LTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAI
                                     : :   ::.: :..: .: : .: . .::.
NP_001                MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGE-KVAV
                              10        20        30        40     

                 70        80        90       100       110        
pF1KE0 KVIPRNRV--LGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLER
       ::: ....  :. . : . : :   . :.        ::...:: . ..::  ..:.:: 
NP_001 KVIDKTKLDTLATGHLFQEVRC---MKLVQ-------HPNIVRLYEVIDTQTKLYLILEL
           50        60           70               80        90    

      120       130         140       150       160       170      
pF1KE0 PLPAQDLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRG
          . :.::::   :.: :.:  .. .:.:.: ::..::.  :::::.: ::...  ..:
NP_001 G-DGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG
           100       110        120       130       140       150  

        180        190       200       210       220       230     
pF1KE0 CAKLIDFG-SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGD
        .:: ::: :. .   .  :   :. .:: :: .   .: :  . .::::..:. .:::.
NP_001 LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQ
            160       170       180       190       200       210  

         240             250       260       270       280         
pF1KE0 IPFER--DQE----ILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ--
        ::..  :.:    :.. .   :.::: .:  :: : :   :. : :::::   ::.:  
NP_001 PPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGV
            220       230       240       250       260       270  

         290         300       310                                 
pF1KE0 --TPAE--DVPLNPSKGGPAPLAWSLLP                                
         .::   ..::                                                
NP_001 DPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLL
            280       290       300       310       320       330  

>>XP_005247048 (OMIM: 607505) PREDICTED: PAS domain-cont  (1107 aa)
 initn: 440 init1: 351 opt: 483  Z-score: 236.2  bits: 53.7 E(85289): 2e-06
Smith-Waterman score: 483; 35.9% identity (60.2% similar) in 284 aa overlap (19-289:763-1038)

                           10        20           30             40
pF1KE0             MLTKPLQGPPAPPGTPTPPPGGKDRE---AFEAEYR-----LGPLLGK
                                     :: . . :   : :.::      ..:: :.
XP_005 SLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPL-GS
            740       750       760       770       780        790 

               50        60        70            80        90      
pF1KE0 GGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLEVALLWKVGAGGGH
       :.:: :...       .:..: : ...::   :  .:   .::  ::.:.: .:     :
XP_005 GAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----H
             800       810       820       830         840         

        100       110       120       130       140       150      
pF1KE0 PGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHS
        ..:..:: ::.:  :.::.:.   . ::: .: ..  : :  .  .: :.:.:. . . 
XP_005 ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL
         850       860       870       880       890       900     

        160       170       180       190        200       210     
pF1KE0 RGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRVYSPPEWISRHQYH
       . ..:::::::::.:  .    :::::::.: :.  . .  : ::  :  :: .  . :.
XP_005 KDIIHRDIKDENIVIA-EDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYR
         910       920        930       940       950       960    

         220       230       240       250       260       270     
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
       .    .::::. :: .:  . :: . .: .:: .: :  :: .  .:.   : : :  : 
XP_005 GPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRT
          970       980       990      1000      1010      1020    

         280       290       300       310                         
pF1KE0 SLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP                        
       .::... :::.  :                                              
XP_005 TLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGG
         1030      1040      1050      1060      1070      1080    

>>XP_011509134 (OMIM: 607505) PREDICTED: PAS domain-cont  (1137 aa)
 initn: 440 init1: 351 opt: 483  Z-score: 236.1  bits: 53.7 E(85289): 2.1e-06
Smith-Waterman score: 483; 35.9% identity (60.2% similar) in 284 aa overlap (19-289:793-1068)

                           10        20           30             40
pF1KE0             MLTKPLQGPPAPPGTPTPPPGGKDRE---AFEAEYR-----LGPLLGK
                                     :: . . :   : :.::      ..:: :.
XP_011 SLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPL-GS
            770       780       790       800       810        820 

               50        60        70            80        90      
pF1KE0 GGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLEVALLWKVGAGGGH
       :.:: :...       .:..: : ...::   :  .:   .::  ::.:.: .:     :
XP_011 GAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----H
             830       840       850       860         870         

        100       110       120       130       140       150      
pF1KE0 PGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHS
        ..:..:: ::.:  :.::.:.   . ::: .: ..  : :  .  .: :.:.:. . . 
XP_011 ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL
         880       890       900       910       920       930     

        160       170       180       190        200       210     
pF1KE0 RGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRVYSPPEWISRHQYH
       . ..:::::::::.:  .    :::::::.: :.  . .  : ::  :  :: .  . :.
XP_011 KDIIHRDIKDENIVIA-EDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYR
         940       950        960       970       980       990    

         220       230       240       250       260       270     
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
       .    .::::. :: .:  . :: . .: .:: .: :  :: .  .:.   : : :  : 
XP_011 GPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRT
         1000      1010      1020      1030      1040      1050    

         280       290       300       310                         
pF1KE0 SLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP                        
       .::... :::.  :                                              
XP_011 TLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGG
         1060      1070      1080      1090      1100      1110    

>>NP_001239051 (OMIM: 607505) PAS domain-containing seri  (1288 aa)
 initn: 419 init1: 351 opt: 483  Z-score: 235.6  bits: 53.8 E(85289): 2.2e-06
Smith-Waterman score: 483; 35.9% identity (60.2% similar) in 284 aa overlap (19-289:944-1219)

                           10        20           30             40
pF1KE0             MLTKPLQGPPAPPGTPTPPPGGKDRE---AFEAEYR-----LGPLLGK
                                     :: . . :   : :.::      ..:: :.
NP_001 SLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPL-GS
           920       930       940       950       960       970   

               50        60        70            80        90      
pF1KE0 GGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLEVALLWKVGAGGGH
       :.:: :...       .:..: : ...::   :  .:   .::  ::.:.: .:     :
NP_001 GAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----H
            980       990      1000      1010        1020          

        100       110       120       130       140       150      
pF1KE0 PGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHS
        ..:..:: ::.:  :.::.:.   . ::: .: ..  : :  .  .: :.:.:. . . 
NP_001 ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL
       1030      1040      1050      1060      1070      1080      

        160       170       180       190        200       210     
pF1KE0 RGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRVYSPPEWISRHQYH
       . ..:::::::::.:  .    :::::::.: :.  . .  : ::  :  :: .  . :.
NP_001 KDIIHRDIKDENIVIA-EDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYR
       1090      1100       1110      1120      1130      1140     

         220       230       240       250       260       270     
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
       .    .::::. :: .:  . :: . .: .:: .: :  :: .  .:.   : : :  : 
NP_001 GPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRT
        1150      1160      1170      1180      1190      1200     

         280       290       300       310                         
pF1KE0 SLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP                        
       .::... :::.  :                                              
NP_001 TLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGG
        1210      1220      1230      1240      1250      1260     




311 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:01:02 2016 done: Sat Nov  5 03:01:03 2016
 Total Scan time:  8.820 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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