Result of FASTA (ccds) for pF1KE0729
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0729, 309 aa
  1>>>pF1KE0729 309 - 309 aa - 309 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7083+/-0.00115; mu= 2.8108+/- 0.066
 mean_var=219.3992+/-53.000, 0's: 0 Z-trim(108.8): 695  B-trim: 90 in 1/49
 Lambda= 0.086588
 statistics sampled from 9608 (10430) to 9608 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.32), width:  16
 Scan time:  2.570

The best scores are:                                      opt bits E(32554)
CCDS33128.1 AURKC gene_id:6795|Hs108|chr19         ( 309) 2070 271.7 4.9e-73
CCDS46205.1 AURKC gene_id:6795|Hs108|chr19         ( 290) 1946 256.2 2.2e-68
CCDS46206.1 AURKC gene_id:6795|Hs108|chr19         ( 275) 1855 244.8 5.6e-65
CCDS67162.1 AURKB gene_id:9212|Hs108|chr17         ( 345) 1596 212.6 3.5e-55
CCDS11134.1 AURKB gene_id:9212|Hs108|chr17         ( 344) 1594 212.3 4.2e-55
CCDS58514.1 AURKB gene_id:9212|Hs108|chr17         ( 303) 1582 210.8 1.1e-54
CCDS13451.1 AURKA gene_id:6790|Hs108|chr20         ( 403) 1316 177.7 1.3e-44
CCDS82065.1 AURKB gene_id:9212|Hs108|chr17         ( 312) 1204 163.6 1.8e-40
CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11         (1261)  618 91.0   5e-18
CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11          (1321)  618 91.0 5.2e-18
CCDS3735.1 PLK4 gene_id:10733|Hs108|chr4           ( 970)  609 89.8 9.2e-18
CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14         ( 713)  600 88.5 1.6e-17
CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14         ( 729)  600 88.5 1.7e-17
CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14         ( 744)  600 88.5 1.7e-17
CCDS45165.1 MARK3 gene_id:4140|Hs108|chr14         ( 753)  600 88.5 1.7e-17
CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19        ( 688)  589 87.1 4.2e-17
CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19        ( 752)  589 87.2 4.4e-17
CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12         ( 661)  588 87.0 4.4e-17
CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1          ( 780)  586 86.8 5.9e-17
CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1          ( 795)  586 86.8 5.9e-17
CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1          ( 796)  586 86.8 5.9e-17
CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21        ( 783)  574 85.3 1.7e-16
CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|c ( 783)  574 85.3 1.7e-16
CCDS58750.1 STK36 gene_id:27148|Hs108|chr2         (1294)  576 85.8   2e-16
CCDS2421.1 STK36 gene_id:27148|Hs108|chr2          (1315)  576 85.8   2e-16
CCDS43075.1 SNRK gene_id:54861|Hs108|chr3          ( 765)  570 84.8 2.3e-16
CCDS53651.1 MARK2 gene_id:2011|Hs108|chr11         ( 709)  568 84.5 2.6e-16
CCDS53650.1 MARK2 gene_id:2011|Hs108|chr11         ( 719)  568 84.5 2.6e-16
CCDS8051.2 MARK2 gene_id:2011|Hs108|chr11          ( 724)  568 84.5 2.6e-16
CCDS41665.1 MARK2 gene_id:2011|Hs108|chr11         ( 745)  568 84.5 2.7e-16
CCDS58411.1 PDPK1 gene_id:5170|Hs108|chr16         ( 454)  564 83.8 2.7e-16
CCDS53649.1 MARK2 gene_id:2011|Hs108|chr11         ( 788)  568 84.5 2.8e-16
CCDS10472.1 PDPK1 gene_id:5170|Hs108|chr16         ( 556)  564 83.9 3.1e-16
CCDS6625.1 PRKACG gene_id:5568|Hs108|chr9          ( 351)  557 82.8 4.2e-16
CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11          ( 926)  562 83.9 5.2e-16
CCDS14125.1 PRKX gene_id:5613|Hs108|chrX           ( 358)  553 82.3 6.1e-16
CCDS76779.1 ULK3 gene_id:25989|Hs108|chr15         ( 470)  552 82.3 7.9e-16
CCDS45305.1 ULK3 gene_id:25989|Hs108|chr15         ( 472)  552 82.3 7.9e-16
CCDS12304.1 PRKACA gene_id:5566|Hs108|chr19        ( 351)  549 81.8 8.5e-16
CCDS72813.1 PRKACB gene_id:5567|Hs108|chr1         ( 339)  546 81.4 1.1e-15
CCDS691.1 PRKACB gene_id:5567|Hs108|chr1           ( 351)  546 81.4 1.1e-15
CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1          ( 672)  551 82.3 1.1e-15
CCDS55610.1 PRKACB gene_id:5567|Hs108|chr1         ( 355)  546 81.4 1.1e-15
CCDS72815.1 PRKACB gene_id:5567|Hs108|chr1         ( 357)  546 81.4 1.1e-15
CCDS9752.1 PRKCH gene_id:5583|Hs108|chr14          ( 683)  551 82.4 1.1e-15
CCDS55609.1 PRKACB gene_id:5567|Hs108|chr1         ( 358)  546 81.4 1.1e-15
CCDS693.1 PRKACB gene_id:5567|Hs108|chr1           ( 398)  546 81.5 1.2e-15
CCDS12305.1 PRKACA gene_id:5566|Hs108|chr19        ( 343)  543 81.0 1.4e-15
CCDS72816.1 PRKACB gene_id:5567|Hs108|chr1         ( 338)  538 80.4 2.1e-15
CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3           ( 370)  533 79.8 3.5e-15


>>CCDS33128.1 AURKC gene_id:6795|Hs108|chr19              (309 aa)
 initn: 2070 init1: 2070 opt: 2070  Z-score: 1424.6  bits: 271.7 E(32554): 4.9e-73
Smith-Waterman score: 2070; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)

               10        20        30        40        50        60
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
              250       260       270       280       290       300

                
pF1KE0 LPPCAQMAS
       :::::::::
CCDS33 LPPCAQMAS
                

>>CCDS46205.1 AURKC gene_id:6795|Hs108|chr19              (290 aa)
 initn: 1946 init1: 1946 opt: 1946  Z-score: 1341.3  bits: 256.2 E(32554): 2.2e-68
Smith-Waterman score: 1946; 99.7% identity (100.0% similar) in 290 aa overlap (20-309:1-290)

               10        20        30        40        50        60
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
                          .::::::::::::::::::::::::::::::::::::::::
CCDS46                    MATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
                                  10        20        30        40 

               70        80        90       100       110       120
pF1KE0 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
              50        60        70        80        90       100 

              130       140       150       160       170       180
pF1KE0 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
             110       120       130       140       150       160 

              190       200       210       220       230       240
pF1KE0 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
             170       180       190       200       210       220 

              250       260       270       280       290       300
pF1KE0 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
             230       240       250       260       270       280 

                
pF1KE0 LPPCAQMAS
       :::::::::
CCDS46 LPPCAQMAS
             290

>>CCDS46206.1 AURKC gene_id:6795|Hs108|chr19              (275 aa)
 initn: 1855 init1: 1855 opt: 1855  Z-score: 1280.1  bits: 244.8 E(32554): 5.6e-65
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 275 aa overlap (35-309:1-275)

           10        20        30        40        50        60    
pF1KE0 RAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKE
                                     ::::::::::::::::::::::::::::::
CCDS46                               MRRLTVDDFEIGRPLGKGKFGNVYLARLKE
                                             10        20        30

           70        80        90       100       110       120    
pF1KE0 SHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAP
               40        50        60        70        80        90

          130       140       150       160       170       180    
pF1KE0 RGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIAD
              100       110       120       130       140       150

          190       200       210       220       230       240    
pF1KE0 FGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 FGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASH
              160       170       180       190       200       210

          250       260       270       280       290       300    
pF1KE0 SETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPC
              220       230       240       250       260       270

            
pF1KE0 AQMAS
       :::::
CCDS46 AQMAS
            

>>CCDS67162.1 AURKB gene_id:9212|Hs108|chr17              (345 aa)
 initn: 1563 init1: 1563 opt: 1596  Z-score: 1104.1  bits: 212.6 E(32554): 3.5e-55
Smith-Waterman score: 1596; 76.8% identity (90.8% similar) in 306 aa overlap (3-305:35-340)

                                           10           20         
pF1KE0                             MSSPRAVVQLGKA--QP-AGEELATANQTAQQ
                                     .: :.: ....  :: :.    . ....  
CCDS67 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGT
           10        20        30        40        50        60    

      30        40        50        60        70        80         
pF1KE0 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR
       :.  . :..:.::::::::::::::::::::: :.:::::::::::::::::::.:::::
CCDS67 PDILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLR
           70        80        90       100       110       120    

      90       100       110       120       130       140         
pF1KE0 REIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEE
       :::::::::.:::::::::::.: ::.:::::::::::::::::::  .::::::::.::
CCDS67 REIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEE
          130       140       150       160       170       180    

     150       160       170       180       190       200         
pF1KE0 LADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPE
       ::::: ::: ::::::::::::::::..::.::::::::::.::::::::::::::::::
CCDS67 LADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPE
          190       200       210       220       230       240    

     210       220       230       240       250       260         
pF1KE0 MIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDL
       ::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.:.::.::
CCDS67 MIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDL
          250       260       270       280       290       300    

     270       280       290       300          
pF1KE0 ISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS 
       ::.:::..: :::::::.  ::::.:.::::::: :     
CCDS67 ISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
          310       320       330       340     

>>CCDS11134.1 AURKB gene_id:9212|Hs108|chr17              (344 aa)
 initn: 1580 init1: 1580 opt: 1594  Z-score: 1102.7  bits: 212.3 E(32554): 4.2e-55
Smith-Waterman score: 1594; 77.0% identity (90.6% similar) in 309 aa overlap (3-305:35-339)

                                           10          20        30
pF1KE0                             MSSPRAVVQLGKA--QPAGEELATANQTAQQP
                                     .: :.: ....  ::.    :. .: ... 
CCDS11 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPT----AAPGQKVMEN
           10        20        30        40        50            60

                   40        50        60        70        80      
pF1KE0 SS--PAM--RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH
       ::  : .  :..:.::::::::::::::::::::: :.:::::::::::::::::::.::
CCDS11 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
               70        80        90       100       110       120

         90       100       110       120       130       140      
pF1KE0 QLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI
       ::::::::::::.:::::::::::.: ::.:::::::::::::::::::  .::::::::
CCDS11 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
              130       140       150       160       170       180

        150       160       170       180       190       200      
pF1KE0 IEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYL
       .::::::: ::: ::::::::::::::::..::.::::::::::.:::::::::::::::
CCDS11 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
              190       200       210       220       230       240

        210       220       230       240       250       260      
pF1KE0 PPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA
       :::::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.:.::
CCDS11 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
              250       260       270       280       290       300

        270       280       290       300          
pF1KE0 RDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS 
       .::::.:::..: :::::::.  ::::.:.::::::: :     
CCDS11 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              310       320       330       340    

>>CCDS58514.1 AURKB gene_id:9212|Hs108|chr17              (303 aa)
 initn: 1580 init1: 1580 opt: 1582  Z-score: 1095.3  bits: 210.8 E(32554): 1.1e-54
Smith-Waterman score: 1582; 80.6% identity (92.7% similar) in 289 aa overlap (21-305:10-298)

               10        20        30            40        50      
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSS--PAM--RRLTVDDFEIGRPLGKGKFGN
                           :. .: ... ::  : .  :..:.::::::::::::::::
CCDS58            MSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGN
                          10        20        30        40         

         60        70        80        90       100       110      
pF1KE0 VYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRV
       ::::: :.:::::::::::::::::::.::::::::::::::.:::::::::::.: ::.
CCDS58 VYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRI
      50        60        70        80        90       100         

        120       130       140       150       160       170      
pF1KE0 YLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGF
       :::::::::::::::::::  .::::::::.::::::: ::: ::::::::::::::::.
CCDS58 YLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGL
     110       120       130       140       150       160         

        180       190       200       210       220       230      
pF1KE0 RGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGY
       .::.::::::::::.::::::::::::::::::::::: ..:::::::::::::::::: 
CCDS58 KGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGN
     170       180       190       200       210       220         

        240       250       260       270       280       290      
pF1KE0 PPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAH
       ::::::::.::::::.:::..:: :.:.::.::::.:::..: :::::::.  ::::.:.
CCDS58 PPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRAN
     230       240       250       260       270       280         

        300          
pF1KE0 SRRVLPPCAQMAS 
       ::::::: :     
CCDS58 SRRVLPPSALQSVA
     290       300   

>>CCDS13451.1 AURKA gene_id:6790|Hs108|chr20              (403 aa)
 initn: 1300 init1: 1300 opt: 1316  Z-score: 914.2  bits: 177.7 E(32554): 1.3e-44
Smith-Waterman score: 1316; 68.1% identity (86.5% similar) in 282 aa overlap (18-299:112-389)

                            10        20        30        40       
pF1KE0              MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGR
                                     ::::. ... .. .    :. ...::::::
CCDS13 TSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKK----RQWALEDFEIGR
              90       100       110       120           130       

        50        60        70        80        90       100       
pF1KE0 PLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLY
       :::::::::::::: :.:.::.:::::::.:.:: :.:::::::.:::.::.::::::::
CCDS13 PLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLY
       140       150       160       170       180       190       

       110       120       130       140       150       160       
pF1KE0 NYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDI
       .::::: :::::::::: : .:.::::  :.::::::: : :::.::.:::.:.::::::
CCDS13 GYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDI
       200       210       220       230       240       250       

       170       180       190       200       210       220       
pF1KE0 KPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGV
       ::::::::  ::.::::::::::.:: :: :.::::::::::::::: .::::::: .::
CCDS13 KPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV
       260       270       280       290       300       310       

       230       240       250       260       270       280       
pF1KE0 LCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQI
       ::::.::: ::::. ...:::.:: .:.  ::  .  ::::::::::...: .:  : ..
CCDS13 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV
       320       330       340       350       360       370       

       290       300             
pF1KE0 LKHPWVQAHSRRVLPPCAQMAS    
       :.:::. :.: .              
CCDS13 LEHPWITANSSKPSNCQNKESASKQS
       380       390       400   

>>CCDS82065.1 AURKB gene_id:9212|Hs108|chr17              (312 aa)
 initn: 1286 init1: 1204 opt: 1204  Z-score: 839.9  bits: 163.6 E(32554): 1.8e-40
Smith-Waterman score: 1235; 64.1% identity (77.7% similar) in 309 aa overlap (3-305:35-307)

                                           10          20        30
pF1KE0                             MSSPRAVVQLGKA--QPAGEELATANQTAQQP
                                     .: :.: ....  ::.    :. .: ... 
CCDS82 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPT----AAPGQKVMEN
           10        20        30        40        50            60

                   40        50        60        70        80      
pF1KE0 SS--PAM--RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH
       ::  : .  :..:.:::::::::::                  ::  :.           
CCDS82 SSGTPDILTRHFTIDDFEIGRPLGK------------------ALLCLWP----------
               70        80                          90            

         90       100       110       120       130       140      
pF1KE0 QLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI
           :    .  .:::::::::::.: ::.:::::::::::::::::::  .::::::::
CCDS82 ----EASSVSSPSHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
                100       110       120       130       140        

        150       160       170       180       190       200      
pF1KE0 IEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYL
       .::::::: ::: ::::::::::::::::..::.::::::::::.:::::::::::::::
CCDS82 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
      150       160       170       180       190       200        

        210       220       230       240       250       260      
pF1KE0 PPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA
       :::::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.:.::
CCDS82 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
      210       220       230       240       250       260        

        270       280       290       300          
pF1KE0 RDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS 
       .::::.:::..: :::::::.  ::::.:.::::::: :     
CCDS82 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
      270       280       290       300       310  

>>CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11              (1261 aa)
 initn: 598 init1: 274 opt: 618  Z-score: 437.0  bits: 91.0 E(32554): 5e-18
Smith-Waterman score: 618; 34.3% identity (63.4% similar) in 303 aa overlap (15-307:35-336)

                               10        20        30           40 
pF1KE0                 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRR---LTVD
                                     ::.   ..      .: .:: :      . 
CCDS60 AASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMPARIG
           10        20        30        40        50        60    

              50        60        70        80        90       100 
pF1KE0 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP
        .:: : .:::.:. :  :    ..  ::.:.. :.:...:.:. .. ::..:.  : ::
CCDS60 YYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHP
           70        80        90       100        110       120   

             110       120       130       140       150       160 
pF1KE0 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK
       .:.:::. ..  : .::. :::  ::.. .:    .. :...   ..... :. .:: ..
CCDS60 HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN
           130       140       150       160       170       180   

             170       180        190       200       210          
pF1KE0 VIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD-EK
       ..:::.: :::::    ..::::::.: . ::.   :: ::.  :  ::..::. ::  :
CCDS60 IVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPK
           190       200       210       220       230       240   

     220       230       240       250       260       270         
pF1KE0 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL
       ::.: .::. : :. :  ::.... ..   :.:.   :.:. :    . :: ..:  .: 
CCDS60 VDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPN
           250       260       270       280       290       300   

     280       290            300                                  
pF1KE0 ERLPLAQILKHPWVQ-----AHSRRVLPPCAQMAS                         
       .:: . :: :: :..      .  :..  : :.                           
CCDS60 KRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQT
           310       320       330       340       350       360   

CCDS60 LQAEQAGTAMNISVPQVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVG
           370       380       390       400       410       420   

>>CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11               (1321 aa)
 initn: 598 init1: 274 opt: 618  Z-score: 436.8  bits: 91.0 E(32554): 5.2e-18
Smith-Waterman score: 618; 34.3% identity (63.4% similar) in 303 aa overlap (15-307:35-336)

                               10        20        30           40 
pF1KE0                 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRR---LTVD
                                     ::.   ..      .: .:: :      . 
CCDS83 AASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMPARIG
           10        20        30        40        50        60    

              50        60        70        80        90       100 
pF1KE0 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP
        .:: : .:::.:. :  :    ..  ::.:.. :.:...:.:. .. ::..:.  : ::
CCDS83 YYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHP
           70        80        90       100        110       120   

             110       120       130       140       150       160 
pF1KE0 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK
       .:.:::. ..  : .::. :::  ::.. .:    .. :...   ..... :. .:: ..
CCDS83 HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN
           130       140       150       160       170       180   

             170       180        190       200       210          
pF1KE0 VIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD-EK
       ..:::.: :::::    ..::::::.: . ::.   :: ::.  :  ::..::. ::  :
CCDS83 IVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPK
           190       200       210       220       230       240   

     220       230       240       250       260       270         
pF1KE0 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL
       ::.: .::. : :. :  ::.... ..   :.:.   :.:. :    . :: ..:  .: 
CCDS83 VDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPN
           250       260       270       280       290       300   

     280       290            300                                  
pF1KE0 ERLPLAQILKHPWVQ-----AHSRRVLPPCAQMAS                         
       .:: . :: :: :..      .  :..  : :.                           
CCDS83 KRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQT
           310       320       330       340       350       360   

CCDS83 LQSLRSDAYDHYSAIYSLLCDRHKRHKTLRLGALPSMPRALAFQAPVNIQAEQAGTAMNI
           370       380       390       400       410       420   




309 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:00:27 2016 done: Sat Nov  5 03:00:28 2016
 Total Scan time:  2.570 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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