Result of FASTA (omim) for pF1KE0712
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0712, 411 aa
  1>>>pF1KE0712 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.1214+/-0.000327; mu= -2.8340+/- 0.021
 mean_var=346.8769+/-73.226, 0's: 0 Z-trim(125.2): 16  B-trim: 0 in 0/61
 Lambda= 0.068863
 statistics sampled from 48469 (48488) to 48469 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.836), E-opt: 0.2 (0.569), width:  16
 Scan time: 11.420

The best scores are:                                      opt bits E(85289)
XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cys ( 334)  985 111.0 4.5e-24
XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cys ( 334)  985 111.0 4.5e-24
XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cys ( 391)  985 111.1   5e-24
NP_003140 (OMIM: 602317) SH3 and cysteine-rich dom ( 402)  985 111.1 5.1e-24
XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cys ( 406)  985 111.1 5.1e-24
NP_001278978 (OMIM: 602317) SH3 and cysteine-rich  ( 341)  679 80.6 6.4e-15
XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cys ( 215)  670 79.5 8.7e-15
NP_001273185 (OMIM: 255995,615521) SH3 and cystein ( 325)  467 59.5 1.4e-08
NP_659501 (OMIM: 255995,615521) SH3 and cysteine-r ( 364)  467 59.6 1.5e-08
XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3  ( 364)  467 59.6 1.5e-08
NP_001273186 (OMIM: 255995,615521) SH3 and cystein ( 178)  448 57.4 3.3e-08


>>XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cystein  (334 aa)
 initn: 878 init1: 452 opt: 985  Z-score: 553.2  bits: 111.0 E(85289): 4.5e-24
Smith-Waterman score: 985; 48.4% identity (71.8% similar) in 337 aa overlap (90-411:12-334)

      60        70        80        90       100              110  
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPL------AALKPV-RLHS
                                     .:: :: :.:  :      :.:.:  . :.
XP_011                    MKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHA
                                  10        20        30        40 

            120       130        140       150       160       170 
pF1KE0 FQEHVFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRR
       :::..::. . :..:...::: :.:.::::: ::.:.:  :.. .. :.: ::   .:::
XP_011 FQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRR
              50        60        70        80        90       100 

             180       190       200       210        220       230
pF1KE0 NFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPT
        .:::::.::    :   ::  : . ..::::::::::.:::::   ...: .: :.:: 
XP_011 YYSSPLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPH
             110          120       130       140       150        

               240       250           260       270       280     
pF1KE0 R-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-K
       : : :.  :. :...:       : :      .. ::: :   :.   . ..:....  .
XP_011 RTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQ
      160       170             180       190          200         

          290       300       310       320       330       340    
pF1KE0 ATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPAN
       ..: ::   : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::
XP_011 GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPAN
     210       220       230       240       250       260         

          350       360       370       380       390       400    
pF1KE0 FVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVP
       ::::.. .:...:: . : : :::: ..::::::::.    .. :::::: ::::.::.:
XP_011 FVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLIP
     270       280       290       300         310       320       

          410 
pF1KE0 VDALTEI
       .:.: .:
XP_011 LDVLENI
       330    

>>XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cystein  (334 aa)
 initn: 878 init1: 452 opt: 985  Z-score: 553.2  bits: 111.0 E(85289): 4.5e-24
Smith-Waterman score: 985; 48.4% identity (71.8% similar) in 337 aa overlap (90-411:12-334)

      60        70        80        90       100              110  
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPL------AALKPV-RLHS
                                     .:: :: :.:  :      :.:.:  . :.
XP_016                    MKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHA
                                  10        20        30        40 

            120       130        140       150       160       170 
pF1KE0 FQEHVFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRR
       :::..::. . :..:...::: :.:.::::: ::.:.:  :.. .. :.: ::   .:::
XP_016 FQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRR
              50        60        70        80        90       100 

             180       190       200       210        220       230
pF1KE0 NFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPT
        .:::::.::    :   ::  : . ..::::::::::.:::::   ...: .: :.:: 
XP_016 YYSSPLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPH
             110          120       130       140       150        

               240       250           260       270       280     
pF1KE0 R-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-K
       : : :.  :. :...:       : :      .. ::: :   :.   . ..:....  .
XP_016 RTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQ
      160       170             180       190          200         

          290       300       310       320       330       340    
pF1KE0 ATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPAN
       ..: ::   : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::
XP_016 GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPAN
     210       220       230       240       250       260         

          350       360       370       380       390       400    
pF1KE0 FVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVP
       ::::.. .:...:: . : : :::: ..::::::::.    .. :::::: ::::.::.:
XP_016 FVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLIP
     270       280       290       300         310       320       

          410 
pF1KE0 VDALTEI
       .:.: .:
XP_016 LDVLENI
       330    

>>XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cystein  (391 aa)
 initn: 898 init1: 452 opt: 985  Z-score: 552.4  bits: 111.1 E(85289): 5e-24
Smith-Waterman score: 1021; 44.1% identity (67.8% similar) in 410 aa overlap (12-411:9-391)

               10        20        30        40        50          
pF1KE0 MTEMSEKENEPDDAATHSPPGTVSALQETKLQRFKRSLSLKTILRSKSLENFFLRSGSE-
                  .:..   :  .:.: :  .    . . :    ::::: .::: :..:: 
XP_011    MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKTKSLRSKSADNFFQRTNSED
                  10        20        30        40        50       

      60        70        80        90       100        110        
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RLHSFQEHVF
       .:  .. ...  .:   : : :     :  : .:.        :.:.:  . :.:::..:
XP_011 MKLQAH-MVAEISPSSSPLPAP-----GSLTSTPAR-------AGLHPGGKAHAFQEYIF
        60         70             80               90       100    

      120       130        140       150       160       170       
pF1KE0 KRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPL
       :. . :..:...::: :.:.::::: ::.:.:  :.. .. :.: ::   .::: .::::
XP_011 KKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPL
          110       120       130       140       150       160    

       180       190       200       210        220       230      
pF1KE0 LVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPTR-SLSE
       :.::    :   ::  : . ..::::::::::.:::::   ...: .: :.:: : : :.
XP_011 LIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSD
          170          180       190       200       210       220 

         240       250           260       270       280        290
pF1KE0 RDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-KATLRKD
         :. :...:       : :      .. ::: :   :.   . ..:....  ...: ::
XP_011 LVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQGSLSKD
             230             240          250       260       270  

              300       310       320       330       340       350
pF1KE0 VGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVR
          : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::::::..
XP_011 PLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQ
            280       290       300       310       320       330  

              360       370       380       390       400       410
pF1KE0 PGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTE
        .:...:: . : : :::: ..::::::::  .  .. :::::: ::::.::.:.:.: .
XP_011 QNEKIFRCVRTFIGCKEQGQITLKENQICV--SSEEEQDGFIRVLSGKKKGLIPLDVLEN
            340       350       360         370       380       390

        
pF1KE0 I
       :
XP_011 I
        

>>NP_003140 (OMIM: 602317) SH3 and cysteine-rich domain-  (402 aa)
 initn: 961 init1: 452 opt: 985  Z-score: 552.2  bits: 111.1 E(85289): 5.1e-24
Smith-Waterman score: 1090; 46.4% identity (70.8% similar) in 414 aa overlap (11-411:16-402)

                    10         20         30        40         50  
pF1KE0      MTEMSEKENEPDDAA-THSPPGTVS-ALQETKLQRFKRSLSLKTI-LRSKSLENF
                      : .:. ...::. .: . ::.:::..:::::.::  ::::: .::
NP_003 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
               10        20        30        40        50        60

              60        70        80        90       100        110
pF1KE0 FLRSGSE-LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RL
       : :..:: .:  .. ...  .:   : : :     :  : .:.        :.:.:  . 
NP_003 FQRTNSEDMKLQAH-MVAEISPSSSPLPAP-----GSLTSTPAR-------AGLHPGGKA
               70         80             90              100       

              120       130        140       150       160         
pF1KE0 HSFQEHVFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSF
       :.:::..::. . :..:...::: :.:.::::: ::.:.:  :.. .. :.: ::   .:
NP_003 HAFQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGF
       110       120       130       140       150       160       

     170       180       190       200       210        220        
pF1KE0 RRNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSES
       :: .:::::.::    :   ::  : . ..::::::::::.:::::   ...: .: :.:
NP_003 RRYYSSPLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDS
       170       180          190       200       210       220    

      230        240       250           260       270       280   
pF1KE0 PTR-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP
       : : : :.  :. :...:       : :      .. ::: :   :.   . ..:.... 
NP_003 PHRTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNIN
          230       240             250       260          270     

            290       300       310       320       330       340  
pF1KE0 -KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFP
        ...: ::   : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::
NP_003 HQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFP
         280       290       300       310       320       330     

            350       360       370       380       390       400  
pF1KE0 ANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGL
       ::::::.. .:...:: . : : :::: ..::::::::.    .. :::::: ::::.::
NP_003 ANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGL
         340       350       360       370         380       390   

            410 
pF1KE0 VPVDALTEI
       .:.:.: .:
NP_003 IPLDVLENI
           400  

>>XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cystein  (406 aa)
 initn: 977 init1: 452 opt: 985  Z-score: 552.2  bits: 111.1 E(85289): 5.1e-24
Smith-Waterman score: 1057; 47.1% identity (70.7% similar) in 393 aa overlap (30-411:41-406)

                10        20        30        40         50        
pF1KE0  MTEMSEKENEPDDAATHSPPGTVSALQETKLQRFKRSLSLKTI-LRSKSLENFFLRSGS
                                     .::..:::::.::  ::::: .::: :..:
XP_011 ISCIHSIHPRASWGKIEEASHALNYQGNIFQLQKLKRSLSFKTKSLRSKSADNFFQRTNS
               20        30        40        50        60        70

        60        70        80        90       100        110      
pF1KE0 E-LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RLHSFQEH
       : .:  .. ...  .:   : : :     :  : .:.     :  :.:.:  . :.:::.
XP_011 EDMKLQAH-MVAEISPSSSPLPAP-----GSLTSTPA-----R--AGLHPGGKAHAFQEY
                80        90            100              110       

        120       130        140       150       160       170     
pF1KE0 VFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSS
       .::. . :..:...::: :.:.::::: ::.:.:  :.. .. :.: ::   .::: .::
XP_011 IFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSS
       120       130       140       150       160       170       

         180       190       200       210        220       230    
pF1KE0 PLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPTR-SL
       :::.::    :   ::  : . ..::::::::::.:::::   ...: .: :.:: : : 
XP_011 PLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTST
       180          190       200       210       220       230    

           240       250           260       270       280         
pF1KE0 SERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-KATLR
       :.  :. :...:       : :      .. ::: :   :.   . ..:....  ...: 
XP_011 SDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQGSLS
          240             250       260          270       280     

      290       300       310       320       330       340        
pF1KE0 KDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQR
       ::   : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::::::
XP_011 KDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQR
         290       300       310       320       330       340     

      350       360       370       380       390       400        
pF1KE0 VRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDAL
       .. .:...:: . : : :::: ..::::::::.    .. :::::: ::::.::.:.:.:
XP_011 LQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLIPLDVL
         350       360       370         380       390       400   

      410 
pF1KE0 TEI
        .:
XP_011 ENI
          

>>NP_001278978 (OMIM: 602317) SH3 and cysteine-rich doma  (341 aa)
 initn: 842 init1: 452 opt: 679  Z-score: 388.8  bits: 80.6 E(85289): 6.4e-15
Smith-Waterman score: 766; 39.2% identity (60.8% similar) in 413 aa overlap (11-411:16-341)

                    10         20         30        40         50  
pF1KE0      MTEMSEKENEPDDAA-THSPPGTVS-ALQETKLQRFKRSLSLKTI-LRSKSLENF
                      : .:. ...::. .: . ::.:::..:::::.::  ::::: .::
NP_001 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
               10        20        30        40        50        60

              60        70        80        90       100        110
pF1KE0 FLRSGSE-LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RL
       : :..:: .:  .. ...  .:   : : :     :  : .:.        :.:.:  . 
NP_001 FQRTNSEDMKLQAH-MVAEISPSSSPLPAP-----GSLTSTPAR-------AGLHPGGKA
               70         80             90              100       

              120       130       140       150       160       170
pF1KE0 HSFQEHVFKRASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFR
       :.:::..::. . :..:...::.                           :         
NP_001 HAFQEYIFKKPTFCDVCNHMIVA---------------------------C---------
       110       120       130                                     

              180       190       200       210        220         
pF1KE0 RNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESP
                                  ..::::::::::.:::::   ...: .: :.::
NP_001 ---------------------------GNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSP
                                        140       150       160    

     230        240       250           260       270       280    
pF1KE0 TR-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-
        : : :.  :. :...:       : :      .. ::: :   :.   . ..:....  
NP_001 HRTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINH
          170       180             190          200       210     

           290       300       310       320       330       340   
pF1KE0 KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPA
       ...: ::   : .:::::::.::::.:: ..::: : :..::::::::::: ::.:::::
NP_001 QGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPA
         220       230       240       250       260       270     

           350       360       370       380       390       400   
pF1KE0 NFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLV
       :::::.. .:...:: . : : :::: ..::::::::.    .. :::::: ::::.::.
NP_001 NFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLI
         280       290       300       310         320       330   

           410 
pF1KE0 PVDALTEI
       :.:.: .:
NP_001 PLDVLENI
           340 

>>XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cystein  (215 aa)
 initn: 641 init1: 452 opt: 670  Z-score: 386.5  bits: 79.5 E(85289): 8.7e-15
Smith-Waterman score: 670; 50.2% identity (73.3% similar) in 225 aa overlap (194-411:2-215)

           170       180       190       200       210        220  
pF1KE0 KTSTSFRRNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSF
                                     : . ..::::::::::.:::::   ...: 
XP_016                              MPIACGNKVDPVYETLRFGTSLAQRTKKGSS
                                            10        20        30 

            230        240       250           260       270       
pF1KE0 SSTSESPTR-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKS
       .: :.:: : : :.  :. :...:       : :      .. ::: :   :.   . ..
XP_016 GSGSDSPHRTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRD
              40        50              60        70           80  

       280        290       300       310       320       330      
pF1KE0 PGQQLP-KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGD
       :....  ...: ::   : .:::::::.::::.:: ..::: : :..::::::::::: :
XP_016 PAKNINHQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQD
             90       100       110       120       130       140  

        340       350       360       370       380       390      
pF1KE0 RVGFFPANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSS
       :.::::::::::.. .:...:: . : : :::: ..::::::::.    .. :::::: :
XP_016 RIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLS
            150       160       170       180         190       200

        400       410 
pF1KE0 GKKRGLVPVDALTEI
       :::.::.:.:.: .:
XP_016 GKKKGLIPLDVLENI
              210     

>>NP_001273185 (OMIM: 255995,615521) SH3 and cysteine-ri  (325 aa)
 initn: 758 init1: 340 opt: 467  Z-score: 275.2  bits: 59.5 E(85289): 1.4e-08
Smith-Waterman score: 732; 38.8% identity (64.4% similar) in 317 aa overlap (95-411:38-325)

           70        80        90       100       110       120    
pF1KE0 EVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFKRASPC
                                     : : :  :.  ::   :.:..: ::. . :
NP_001 QANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKP---HKFKDHFFKKPKFC
        10        20        30        40        50           60    

          130       140       150       160       170       180    
pF1KE0 ELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHEPPP
       ..: ..:: :.: ::::: ::...:  :.  .  :.: ::   .:.: .::::  ..   
NP_001 DVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQY-
           70        80        90       100       110       120    

          190       200       210       220       230       240    
pF1KE0 VCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDELTEDGE
       .:. .  .     ... :::.:::: :. .:  .:.. .. ...:. .. :     :. :
NP_001 ACVKDLSA-----ANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME-----EEPE
           130            140       150       160            170   

          250       260       270       280       290       300    
pF1KE0 GSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFL
        : :  :::  ....:     ::.. :  ..:.:: :             . .::::.: 
NP_001 -SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVALYRFK
             180       190       200       210                  220

          310       320       330       340       350       360    
pF1KE0 PQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSG
         :..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : :  . : :
NP_001 ALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVG
              230       240       250       260       270       280

          370       380       390       400       410 
pF1KE0 NKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI
       :.: : ..::..:: :  :   .: :...: .:.: :: :.: : ::
NP_001 NREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI
              290         300       310       320     

>>NP_659501 (OMIM: 255995,615521) SH3 and cysteine-rich   (364 aa)
 initn: 758 init1: 340 opt: 467  Z-score: 274.6  bits: 59.6 E(85289): 1.5e-08
Smith-Waterman score: 735; 34.7% identity (59.7% similar) in 409 aa overlap (4-411:1-364)

               10         20        30        40        50         
pF1KE0 MTEMSEKENEPDDAATHSP-PGTVSALQETKLQRFKRSLSLKTILRSKSLENFFLRSGSE
          :.:::      . .:: :.  .  ... :::      :: .::. :  .  ..   :
NP_659    MTEKE------VLESPKPSFPAETRQSGLQR------LKQLLRKGSTGTKEMELPPE
                        10        20              30        40     

      60        70        80        90       100       110         
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFK
        .   :.. .   :.          ..    : : :   :. :.  ::   :.:..: ::
NP_659 PQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEP---PK-LVNDKP---HKFKDHFFK
          50        60        70        80               90        

     120       130       140       150       160       170         
pF1KE0 RASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLV
       . . :..: ..:: :.: ::::: ::...:  :.  .  :.: ::   .:.: .::::  
NP_659 KPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYS
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KE0 HEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDEL
       ..   .:. .      . ... :::.:::: :. .:  .:.. .. ...:. .. :    
NP_659 NQQY-ACVKD-----LSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME----
      160             170       180       190       200            

     240       250       260       270       280       290         
pF1KE0 TEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVA
        :. : : :  :::  ....:     ::.. :  ..:.:: :             . .::
NP_659 -EEPE-SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVA
       210         220       230       240                  250    

     300       310       320       330       340       350         
pF1KE0 LYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCC
       ::.:   :..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : :  
NP_659 LYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVT
          260       270       280       290       300       310    

     360       370       380       390       400       410 
pF1KE0 QPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI
       . : ::.: : ..::..:: :  :   .: :...: .:.: :: :.: : ::
NP_659 RSFVGNREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI
          320       330         340       350       360    

>>XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 and   (364 aa)
 initn: 758 init1: 340 opt: 467  Z-score: 274.6  bits: 59.6 E(85289): 1.5e-08
Smith-Waterman score: 735; 34.7% identity (59.7% similar) in 409 aa overlap (4-411:1-364)

               10         20        30        40        50         
pF1KE0 MTEMSEKENEPDDAATHSP-PGTVSALQETKLQRFKRSLSLKTILRSKSLENFFLRSGSE
          :.:::      . .:: :.  .  ... :::      :: .::. :  .  ..   :
XP_011    MTEKE------VLESPKPSFPAETRQSGLQR------LKQLLRKGSTGTKEMELPPE
                        10        20              30        40     

      60        70        80        90       100       110         
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFK
        .   :.. .   :.          ..    : : :   :. :.  ::   :.:..: ::
XP_011 PQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEP---PK-LVNDKP---HKFKDHFFK
          50        60        70        80               90        

     120       130       140       150       160       170         
pF1KE0 RASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLV
       . . :..: ..:: :.: ::::: ::...:  :.  .  :.: ::   .:.: .::::  
XP_011 KPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYS
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KE0 HEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDEL
       ..   .:. .      . ... :::.:::: :. .:  .:.. .. ...:. .. :    
XP_011 NQQY-ACVKD-----LSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME----
      160             170       180       190       200            

     240       250       260       270       280       290         
pF1KE0 TEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVA
        :. : : :  :::  ....:     ::.. :  ..:.:: :             . .::
XP_011 -EEPE-SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVA
       210         220       230       240                  250    

     300       310       320       330       340       350         
pF1KE0 LYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCC
       ::.:   :..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : :  
XP_011 LYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVT
          260       270       280       290       300       310    

     360       370       380       390       400       410 
pF1KE0 QPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI
       . : ::.: : ..::..:: :  :   .: :...: .:.: :: :.: : ::
XP_011 RSFVGNREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI
          320       330         340       350       360    




411 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:55:40 2016 done: Sat Nov  5 02:55:41 2016
 Total Scan time: 11.420 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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