Result of FASTA (omim) for pF1KE0595
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0595, 170 aa
  1>>>pF1KE0595 170 - 170 aa - 170 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7456+/-0.000304; mu= 17.0927+/- 0.019
 mean_var=97.2913+/-19.899, 0's: 0 Z-trim(119.4): 293  B-trim: 1003 in 2/53
 Lambda= 0.130028
 statistics sampled from 32921 (33286) to 32921 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.39), width:  16
 Scan time:  5.410

The best scores are:                                      opt bits E(85289)
NP_036278 (OMIM: 611441) double homeobox protein 1 ( 170) 1159 226.6 1.5e-59
NP_036281 (OMIM: 611444) double homeobox protein 5 ( 197) 1159 226.7 1.6e-59
NP_001280727 (OMIM: 606009) double homeobox protei ( 424)  926 183.4 3.7e-46
NP_001292997 (OMIM: 606009) double homeobox protei ( 424)  926 183.4 3.7e-46
XP_011529816 (OMIM: 606009) PREDICTED: double home ( 160)  890 176.2 2.2e-44
NP_001012747 (OMIM: 611168) double homeobox protei ( 204)  265 59.0   5e-09
NP_006252 (OMIM: 262600,601538) homeobox protein p ( 226)  235 53.5 2.6e-07
NP_114150 (OMIM: 609852) homeobox protein MIXL1 is ( 232)  232 52.9 3.9e-07
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184)  227 51.9 6.5e-07
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230)  227 52.0 7.5e-07
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299)  228 52.3 7.7e-07
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354)  228 52.4 8.6e-07
NP_001186699 (OMIM: 600036) homeobox protein OTX1  ( 354)  228 52.4 8.6e-07
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193)  221 50.8 1.5e-06
NP_057391 (OMIM: 604675) paired mesoderm homeobox  ( 253)  221 50.9 1.7e-06
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297)  219 50.6 2.5e-06
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297)  219 50.6 2.5e-06
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505)  221 51.3 2.7e-06
NP_039236 (OMIM: 167410,268220) paired box protein ( 518)  221 51.3 2.7e-06
NP_002575 (OMIM: 167410,268220) paired box protein ( 520)  221 51.3 2.7e-06
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346)  219 50.7 2.7e-06
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403)  218 50.6 3.4e-06
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407)  218 50.6 3.4e-06
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479)  218 50.7 3.8e-06
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483)  218 50.7 3.8e-06
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484)  218 50.7 3.8e-06
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505)  218 50.7 3.9e-06
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289)  214 49.7 4.7e-06
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289)  214 49.7 4.7e-06
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289)  214 49.7 4.7e-06
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302)  213 49.5 5.5e-06
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284)  211 49.1 6.8e-06
XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280)  210 48.9 7.7e-06
XP_016862910 (OMIM: 182230,601802) PREDICTED: home ( 185)  208 48.3 7.8e-06
XP_006713442 (OMIM: 182230,601802) PREDICTED: home ( 185)  208 48.3 7.8e-06
XP_011532506 (OMIM: 182230,601802) PREDICTED: home ( 185)  208 48.3 7.8e-06
NP_003856 (OMIM: 182230,601802) homeobox expressed ( 185)  208 48.3 7.8e-06
XP_011532507 (OMIM: 182230,601802) PREDICTED: home ( 185)  208 48.3 7.8e-06
XP_005265583 (OMIM: 182230,601802) PREDICTED: home ( 185)  208 48.3 7.8e-06
NP_878314 (OMIM: 142993,610092,610093) visual syst ( 361)  211 49.2 7.9e-06
NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301)  210 48.9 8.1e-06
NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365)  210 49.0 9.1e-06
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325)  209 48.8 9.6e-06
NP_001269331 (OMIM: 609852) homeobox protein MIXL1 ( 240)  206 48.1 1.2e-05
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382)  208 48.7 1.2e-05
XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198)  204 47.6 1.4e-05
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377)  207 48.5 1.4e-05
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377)  207 48.5 1.4e-05
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377)  207 48.5 1.4e-05
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314)  206 48.2 1.4e-05


>>NP_036278 (OMIM: 611441) double homeobox protein 1 [Ho  (170 aa)
 initn: 1159 init1: 1159 opt: 1159  Z-score: 1190.3  bits: 226.6 E(85289): 1.5e-59
Smith-Waterman score: 1159; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)

               10        20        30        40        50        60
pF1KE0 MALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPG
               70        80        90       100       110       120

              130       140       150       160       170
pF1KE0 IAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG
              130       140       150       160       170

>>NP_036281 (OMIM: 611444) double homeobox protein 5 [Ho  (197 aa)
 initn: 1159 init1: 1159 opt: 1159  Z-score: 1189.6  bits: 226.7 E(85289): 1.6e-59
Smith-Waterman score: 1159; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:28-197)

                                          10        20        30   
pF1KE0                            MALLTALDDTLPEEAQGPGRRMILLSTPSQSDA
                                  :::::::::::::::::::::::::::::::::
NP_036 MPAEVHGSPPASLCPCQSVKFRPGLPEMALLTALDDTLPEEAQGPGRRMILLSTPSQSDA
               10        20        30        40        50        60

            40        50        60        70        80        90   
pF1KE0 LRACFERNLYPGIATKEELAQGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LRACFERNLYPGIATKEELAQGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQK
               70        80        90       100       110       120

           100       110       120       130       140       150   
pF1KE0 GRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQS
              130       140       150       160       170       180

           160       170
pF1KE0 GRAPTQASIRCNAAPIG
       :::::::::::::::::
NP_036 GRAPTQASIRCNAAPIG
              190       

>>NP_001280727 (OMIM: 606009) double homeobox protein 4   (424 aa)
 initn: 1124 init1: 926 opt: 926  Z-score: 949.7  bits: 183.4 E(85289): 3.7e-46
Smith-Waterman score: 926; 81.8% identity (90.0% similar) in 170 aa overlap (1-170:1-170)

               10        20        30        40        50        60
pF1KE0 MALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPE
       ::: :  :.::: ::.: :::  :. :::::.::::::::: ::::::.:.:::.: :::
NP_001 MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPG
       :::::::::::: :::::::.:::::::: : .:::::::.:::::::::::::::::::
NP_001 PRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPG
               70        80        90       100       110       120

              130       140       150       160       170          
pF1KE0 IAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG          
       ::::::::::::::::::::::::::::: ::.::::.::.  :.::: :          
NP_001 IAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAF
              130       140       150       160       170       180

NP_001 AHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGISQPAPARGDFA
              190       200       210       220       230       240

>>NP_001292997 (OMIM: 606009) double homeobox protein 4   (424 aa)
 initn: 1124 init1: 926 opt: 926  Z-score: 949.7  bits: 183.4 E(85289): 3.7e-46
Smith-Waterman score: 926; 81.8% identity (90.0% similar) in 170 aa overlap (1-170:1-170)

               10        20        30        40        50        60
pF1KE0 MALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPE
       ::: :  :.::: ::.: :::  :. :::::.::::::::: ::::::.:.:::.: :::
NP_001 MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPG
       :::::::::::: :::::::.:::::::: : .:::::::.:::::::::::::::::::
NP_001 PRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPG
               70        80        90       100       110       120

              130       140       150       160       170          
pF1KE0 IAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG          
       ::::::::::::::::::::::::::::: ::.::::.::.  :.::: :          
NP_001 IAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAF
              130       140       150       160       170       180

NP_001 AHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGISQPAPARGDFA
              190       200       210       220       230       240

>>XP_011529816 (OMIM: 606009) PREDICTED: double homeobox  (160 aa)
 initn: 1088 init1: 890 opt: 890  Z-score: 917.9  bits: 176.2 E(85289): 2.2e-44
Smith-Waterman score: 890; 83.6% identity (91.2% similar) in 159 aa overlap (1-159:1-159)

               10        20        30        40        50        60
pF1KE0 MALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPE
       ::: :  :.::: ::.: :::  :. :::::.::::::::: ::::::.:.:::.: :::
XP_011 MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPG
       :::::::::::: :::::::.:::::::: : .:::::::.:::::::::::::::::::
XP_011 PRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPG
               70        80        90       100       110       120

              130       140       150       160       170
pF1KE0 IAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG
       ::::::::::::::::::::::::::::: ::.::::.:           
XP_011 IAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQV          
              130       140       150       160          

>>NP_001012747 (OMIM: 611168) double homeobox protein A   (204 aa)
 initn: 233 init1: 233 opt: 265  Z-score: 283.1  bits: 59.0 E(85289): 5e-09
Smith-Waterman score: 363; 43.6% identity (63.8% similar) in 149 aa overlap (20-157:16-164)

               10        20        30        40        50        60
pF1KE0 MALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPE
                          ::     :  :   :   :... ::: :::..::  :.  :
NP_001     MAEDTYSHKMVKTNHRRCRTKFTEEQLKILINTFNQKPYPGYATKQKLALEINTEE
                   10        20        30        40        50      

               70                  80         90       100         
pF1KE0 PRVQIWFQNERSCQLRQHR----------RQSRPWPGRR-DPQKGRRKRTAITGSQTALL
        :.::::::.:. .  :.:           :..  :: . . ...:: ::. ..::   :
NP_001 SRIQIWFQNRRARHGFQKRPEAETLESSQSQGQDQPGVEFQSREARRCRTTYSASQLHTL
         60        70        80        90       100       110      

     110       120       130       140       150       160         
pF1KE0 LRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPI
       ..:: :. .::: .:::::.: :.::::.::::::::.:   :  : :            
NP_001 IKAFMKNPYPGIDSREELAKEIGVPESRVQIWFQNRRSRLLLQRKREPVASLEQEEQGKI
        120       130       140       150       160       170      

     170                           
pF1KE0 G                           
                                   
NP_001 PEGLQGAEDTQNGTNFTSDSHFSGARTW
        180       190       200    

>>NP_006252 (OMIM: 262600,601538) homeobox protein proph  (226 aa)
 initn: 222 init1: 222 opt: 235  Z-score: 252.2  bits: 53.5 E(85289): 2.6e-07
Smith-Waterman score: 235; 49.3% identity (72.0% similar) in 75 aa overlap (79-152:53-127)

       50        60        70        80        90        100       
pF1KE0 KEELAQGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRD-PQKGRRKRTAITGSQTA
                                     : .  :  :.:  :.. ::.::...  :  
NP_006 PERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLE
             30        40        50        60        70        80  

       110       120       130       140       150       160       
pF1KE0 LLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAA
        :  :: ....: : ::: :::.::: :.:::.:::::::..: :               
NP_006 QLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSPAA
             90       100       110       120       130       140  

       170                                                         
pF1KE0 PIG                                                         
                                                                   
NP_006 FSSFLPESTACPYSYAAPPPPVTCFPHPYSHALPSQPSTGGAFALSHQSEDWYPTLHPAP
            150       160       170       180       190       200  

>>NP_114150 (OMIM: 609852) homeobox protein MIXL1 isofor  (232 aa)
 initn: 251 init1: 228 opt: 232  Z-score: 249.0  bits: 52.9 E(85289): 3.9e-07
Smith-Waterman score: 232; 51.4% identity (71.6% similar) in 74 aa overlap (84-156:75-148)

            60        70        80        90        100       110  
pF1KE0 QGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKG-RRKRTAITGSQTALLLRA
                                     :  :   :. . :::::.... :  ::  .
NP_114 AGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELV
           50        60        70        80        90       100    

            120       130       140       150       160       170  
pF1KE0 FEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG  
       :.. :.: :  ::.::  : :::::::.:::::::. : :::..                
NP_114 FRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAP
          110       120       130       140       150       160    

NP_114 GTETKCLKPQLPLEVDVNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEH
          170       180       190       200       210       220    

>>NP_116142 (OMIM: 605726,610362,610381,613757) retina a  (184 aa)
 initn: 221 init1: 206 opt: 227  Z-score: 245.1  bits: 51.9 E(85289): 6.5e-07
Smith-Waterman score: 227; 46.6% identity (68.2% similar) in 88 aa overlap (86-168:18-104)

          60        70        80        90        100       110    
pF1KE0 IDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKG-RRKRTAITGSQTALLLRAFE
                                     ::.. :.:  ::.::..:  :   : ::::
NP_116              MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFE
                            10        20        30        40       

          120       130       140       150           160       170
pF1KE0 KDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQ----SGRAPTQASIRCNAAPIG
        ...: . .::::: .. ::: :.:.:::::::. : :    :: . . :. :   ::  
NP_116 ASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAV-AAPRLPEAPAL
        50        60        70        80        90        100      

NP_116 PFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASL
        110       120       130       140       150       160      

>>NP_001306003 (OMIM: 605726,610362,610381,613757) retin  (230 aa)
 initn: 206 init1: 206 opt: 227  Z-score: 244.0  bits: 52.0 E(85289): 7.5e-07
Smith-Waterman score: 227; 46.6% identity (68.2% similar) in 88 aa overlap (86-168:64-150)

          60        70        80        90        100       110    
pF1KE0 IDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKG-RRKRTAITGSQTALLLRAFE
                                     ::.. :.:  ::.::..:  :   : ::::
NP_001 PPSVPLPSHQVGAMFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFE
            40        50        60        70        80        90   

          120       130       140       150           160       170
pF1KE0 KDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQ----SGRAPTQASIRCNAAPIG
        ...: . .::::: .. ::: :.:.:::::::. : :    :: . . :. :   ::  
NP_001 ASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAV-AAPRLPEAPAL
           100       110       120       130       140        150  

NP_001 PFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASL
            160       170       180       190       200       210  




170 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 20:48:06 2016 done: Wed Nov  2 20:48:07 2016
 Total Scan time:  5.410 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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