Result of FASTA (omim) for pF1KE0525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0525, 384 aa
  1>>>pF1KE0525 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0711+/-0.000378; mu= 18.0698+/- 0.023
 mean_var=66.1679+/-13.904, 0's: 0 Z-trim(111.8): 21  B-trim: 1015 in 1/54
 Lambda= 0.157671
 statistics sampled from 20491 (20510) to 20491 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.24), width:  16
 Scan time:  7.610

The best scores are:                                      opt bits E(85289)
NP_057411 (OMIM: 606673,613161) beta-ureidopropion ( 384) 2606 601.9 8.3e-172
XP_011528527 (OMIM: 606673,613161) PREDICTED: beta ( 262) 1796 417.5 1.8e-116
XP_011528524 (OMIM: 606673,613161) PREDICTED: beta ( 411) 1798 418.1 1.9e-116
XP_016884315 (OMIM: 606673,613161) PREDICTED: beta ( 337) 1272 298.4 1.7e-80
XP_011528526 (OMIM: 606673,613161) PREDICTED: beta ( 345) 1171 275.4 1.4e-73
XP_011528525 (OMIM: 606673,613161) PREDICTED: beta ( 348) 1171 275.4 1.4e-73
XP_016884317 (OMIM: 606673,613161) PREDICTED: beta ( 266)  810 193.2 5.9e-49
XP_016884316 (OMIM: 606673,613161) PREDICTED: beta ( 276)  810 193.2 6.1e-49
XP_016884314 (OMIM: 606673,613161) PREDICTED: beta ( 340)  810 193.3 7.2e-49
NP_005591 (OMIM: 604618) nitrilase homolog 1 isofo ( 327)  224 60.0 9.3e-09
XP_005245271 (OMIM: 604618) PREDICTED: nitrilase h ( 344)  224 60.0 9.7e-09
XP_005245272 (OMIM: 604618) PREDICTED: nitrilase h ( 344)  224 60.0 9.7e-09
NP_001172022 (OMIM: 604618) nitrilase homolog 1 is ( 312)  217 58.4 2.7e-08
XP_005245273 (OMIM: 604618) PREDICTED: nitrilase h ( 291)  209 56.5 9.1e-08
NP_001172023 (OMIM: 604618) nitrilase homolog 1 is ( 291)  209 56.5 9.1e-08
NP_064587 (OMIM: 616769) omega-amidase NIT2 [Homo  ( 276)  179 49.7 9.8e-06
NP_001172021 (OMIM: 604618) nitrilase homolog 1 is ( 243)  178 49.4   1e-05
XP_006711404 (OMIM: 604618) PREDICTED: nitrilase h ( 260)  178 49.5 1.1e-05
XP_016856860 (OMIM: 604618) PREDICTED: nitrilase h ( 207)  163 46.0 9.7e-05


>>NP_057411 (OMIM: 606673,613161) beta-ureidopropionase   (384 aa)
 initn: 2606 init1: 2606 opt: 2606  Z-score: 3205.5  bits: 601.9 E(85289): 8.3e-172
Smith-Waterman score: 2606; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG
              310       320       330       340       350       360

              370       380    
pF1KE0 RYEMYARELAEAVKSNYSPTIVKE
       ::::::::::::::::::::::::
NP_057 RYEMYARELAEAVKSNYSPTIVKE
              370       380    

>>XP_011528527 (OMIM: 606673,613161) PREDICTED: beta-ure  (262 aa)
 initn: 1796 init1: 1796 opt: 1796  Z-score: 2212.1  bits: 417.5 E(85289): 1.8e-116
Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 262 aa overlap (123-384:1-262)

            100       110       120       130       140       150  
pF1KE0 VSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MPFAFCTREKLPWTEFAESAEDGPTTRFCQ
                                             10        20        30

            160       170       180       190       200       210  
pF1KE0 KLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYM
               40        50        60        70        80        90

            220       230       240       250       260       270  
pF1KE0 EGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEA
              100       110       120       130       140       150

            280       290       300       310       320       330  
pF1KE0 RNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSR
              160       170       180       190       200       210

            340       350       360       370       380    
pF1KE0 SRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
              220       230       240       250       260  

>>XP_011528524 (OMIM: 606673,613161) PREDICTED: beta-ure  (411 aa)
 initn: 1798 init1: 1798 opt: 1798  Z-score: 2211.8  bits: 418.1 E(85289): 1.9e-116
Smith-Waterman score: 2542; 93.4% identity (93.4% similar) in 411 aa overlap (1-384:1-411)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_011 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
              190       200       210       220       230       240

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
              250       260       270       280       290       300

           280       290       300       310       320       330   
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
              310       320       330       340       350       360

           340       350       360       370       380    
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
              370       380       390       400       410 

>>XP_016884315 (OMIM: 606673,613161) PREDICTED: beta-ure  (337 aa)
 initn: 1272 init1: 1272 opt: 1272  Z-score: 1566.4  bits: 298.4 E(85289): 1.7e-80
Smith-Waterman score: 2016; 91.9% identity (91.9% similar) in 332 aa overlap (1-305:1-332)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
              190       200       210       220       230       240

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
              250       260       270       280       290       300

           280       290       300       310       320       330   
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
       ::::::::::::::::::::::::::::::::                            
XP_016 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKDDGQV                       
              310       320       330                              

           340       350       360       370       380    
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE

>>XP_011528526 (OMIM: 606673,613161) PREDICTED: beta-ure  (345 aa)
 initn: 1325 init1: 1171 opt: 1171  Z-score: 1442.0  bits: 275.4 E(85289): 1.4e-73
Smith-Waterman score: 1941; 77.4% identity (77.4% similar) in 411 aa overlap (1-384:1-345)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_011 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
              190       200       210       220       230       240

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
              250       260       270       280       290       300

           280       290       300       310       320       330   
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
       ::::::::::::::::::                                          
XP_011 NAAIANHCFTCAINRVGT------------------------------------------
              310                                                  

           340       350       360       370       380    
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
                               :::::::::::::::::::::::::::
XP_011 ------------------------MTGRYEMYARELAEAVKSNYSPTIVKE
                              320       330       340     

>>XP_011528525 (OMIM: 606673,613161) PREDICTED: beta-ure  (348 aa)
 initn: 1171 init1: 1171 opt: 1171  Z-score: 1442.0  bits: 275.4 E(85289): 1.4e-73
Smith-Waterman score: 1915; 91.5% identity (91.5% similar) in 318 aa overlap (1-291:1-318)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_011 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
              190       200       210       220       230       240

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
              250       260       270       280       290       300

           280       290       300       310       320       330   
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
       ::::::::::::::::::                                          
XP_011 NAAIANHCFTCAINRVGTIMNSPKAPSRFLPRLSNSPLAQGWLLSRSV            
              310       320       330       340                    

>>XP_016884317 (OMIM: 606673,613161) PREDICTED: beta-ure  (266 aa)
 initn: 810 init1: 810 opt: 810  Z-score: 999.9  bits: 193.2 E(85289): 5.9e-49
Smith-Waterman score: 1330; 88.5% identity (88.5% similar) in 234 aa overlap (1-207:1-234)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNERVPVAH
              190       200       210       220       230       240

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
                                                                   
XP_016 RGQKRSHCQSLLHLRHQSSGHHDGQV                                  
              250       260                                        

>>XP_016884316 (OMIM: 606673,613161) PREDICTED: beta-ure  (276 aa)
 initn: 810 init1: 810 opt: 810  Z-score: 999.6  bits: 193.2 E(85289): 6.1e-49
Smith-Waterman score: 1330; 88.5% identity (88.5% similar) in 234 aa overlap (1-207:1-234)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNERVPVAH
              190       200       210       220       230       240

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
                                                                   
XP_016 RGQKRSHCQSLLHLRHQSSGHRALPERVYLGRWKER                        
              250       260       270                              

>>XP_016884314 (OMIM: 606673,613161) PREDICTED: beta-ure  (340 aa)
 initn: 1317 init1: 810 opt: 810  Z-score: 998.3  bits: 193.3 E(85289): 7.2e-49
Smith-Waterman score: 1717; 71.3% identity (73.7% similar) in 411 aa overlap (1-384:1-340)

               10        20        30        40        50        60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
               70        80        90       100       110       120

                                         130       140       150   
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
       ::                           :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
              130       140       150       160       170       180

           160       170       180       190       200       210   
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNE------
              190       200       210       220       230          

           220       230       240       250       260       270   
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
                    :.                                        :.  :
XP_016 -------------RV----------------------------------------PVAHR
                                                               240 

           280       290       300       310       320       330   
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
       .    .:: .         :. .. .::   . :::::::::::::::::::::::::::
XP_016 GQK-RSHCQSLL-------HLRHQ-SSG---HPHQDFGYFYGSSYVAAPDSSRTPGLSRS
              250               260          270       280         

           340       350       360       370       380    
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
     290       300       310       320       330       340

>>NP_005591 (OMIM: 604618) nitrilase homolog 1 isoform 1  (327 aa)
 initn: 237 init1: 152 opt: 224  Z-score: 278.2  bits: 60.0 E(85289): 9.3e-09
Smith-Waterman score: 245; 26.9% identity (52.4% similar) in 294 aa overlap (68-350:33-304)

        40        50        60        70        80        90       
pF1KE0 DLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALH
                                     ::: . ..  . ..:: :   :.   .  .
NP_005 GFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSCELPLVAVCQVTSTPDKQQ
             10        20        30        40        50        60  

         100       110       120       130       140       150     
pF1KE0 --RRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLA
         .    .:. ::  :. .  . ::    : : .:.     ...:    :   .   .::
NP_005 NFKTCAELVREAARLGACLAFLPEA----FDFIARDPAETLHLSEPL-GGKLLEEYTQLA
             70        80            90       100        110       

         160          170       180       190            200       
pF1KE0 KNHDM-VVVSPILER--DSEHGDVLWNTAVVISNSGAVLGKTRKNH-----IPRVGDFNE
       ..  . . .. . ::  : :. . ..:  :.....:::..  ::.:     ::  : . :
NP_005 RECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCE
       120       130       140       150       160       170       

       210        220       230       240       250       260      
pF1KE0 STYYMEG-NLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSES
       :.  : : .:  :: .:  :.:.. .::  . :   :  .  ::::.  :::  .  . .
NP_005 SNSTMPGPSLESPV-STPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPA
       180       190        200       210       220       230      

        270       280       290       300       310       320      
pF1KE0 LWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSR
        : .  :  :: ..:.. :  . : .:          :.:       :: :.:. : .. 
NP_005 HWEVLLRARAIETQCYVVAAAQCGRHHE---------KRAS------YGHSMVVDPWGTV
        240       250       260                      270       280 

        330       340       350       360       370       380    
pF1KE0 TPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
       .   :..  :: .:..:::  .:.                                  
NP_005 VARCSEG-PGLCLARIDLNYLRQLRRHLPVFQHRRPDLYGNLGHPLS           
              290       300       310       320                  




384 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:56:44 2016 done: Thu Nov  3 01:56:45 2016
 Total Scan time:  7.610 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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