Result of FASTA (omim) for pF1KE0329
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0329, 508 aa
  1>>>pF1KE0329 508 - 508 aa - 508 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.6201+/-0.000417; mu= 5.4288+/- 0.026
 mean_var=317.4879+/-64.226, 0's: 0 Z-trim(119.8): 15  B-trim: 0 in 0/59
 Lambda= 0.071980
 statistics sampled from 34190 (34205) to 34190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.401), width:  16
 Scan time: 11.790

The best scores are:                                      opt bits E(85289)
NP_055422 (OMIM: 611216) UBX domain-containing pro ( 508) 3263 352.8 1.3e-96
XP_016873363 (OMIM: 616378) PREDICTED: UBX domain- ( 297)  361 51.2   5e-06
NP_001273006 (OMIM: 616378) UBX domain-containing  ( 297)  361 51.2   5e-06
NP_001273007 (OMIM: 616378) UBX domain-containing  ( 238)  338 48.7 2.3e-05
XP_005274090 (OMIM: 616378) PREDICTED: UBX domain- ( 312)  340 49.0 2.4e-05
NP_056937 (OMIM: 616378) UBX domain-containing pro ( 312)  340 49.0 2.4e-05


>>NP_055422 (OMIM: 611216) UBX domain-containing protein  (508 aa)
 initn: 3263 init1: 3263 opt: 3263  Z-score: 1855.2  bits: 352.8 E(85289): 1.3e-96
Smith-Waterman score: 3263; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)

               10        20        30        40        50        60
pF1KE0 MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 SLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 PFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKK
              430       440       450       460       470       480

              490       500        
pF1KE0 EGKIYRLRTQDDGEDENNTWNGNSTQQM
       ::::::::::::::::::::::::::::
NP_055 EGKIYRLRTQDDGEDENNTWNGNSTQQM
              490       500        

>>XP_016873363 (OMIM: 616378) PREDICTED: UBX domain-cont  (297 aa)
 initn: 354 init1: 218 opt: 361  Z-score: 229.1  bits: 51.2 E(85289): 5e-06
Smith-Waterman score: 363; 31.8% identity (59.2% similar) in 255 aa overlap (156-393:43-291)

         130       140       150       160       170       180     
pF1KE0 QSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQ----
                                     :  :  :   .:  :   . . :::.    
XP_016 MGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGL
             20        30        40        50        60        70  

               190       200         210       220        230      
pF1KE0 EPSGCS--DQRPAEDLNIRVERLTKKLE--ERREEKRKEEEQRE-IKKEIERRKTGKEML
       : :: .  . .:: . . : :.  . ::   .....:.:.:.:: ...: .::. :.:. 
XP_016 EGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELS
             80        90       100       110       120       130  

        240       250       260       270       280           290  
pF1KE0 DYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKT----KEEVEA
         ... .:.  .:  ::: :::::. :::.:....:  :.:::: ... .       :  
XP_016 AARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPPVAP
            140       150       160       170       180       190  

            300       310       320       330       340       350  
pF1KE0 AKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQT
         . .  . . :  .::: : .      ::: :::::.:.:. : .   :  .: ..   
XP_016 EPGPVPSSPSQEPPTKRE-YDQ-----CRIQVRLPDGTSLTQTFRAREQLAAVRLYVELH
            200       210             220       230       240      

                360       370       380       390       400        
pF1KE0 VGNTYGN----FSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSS
        :.  :.     .: . :::: :.. :... : .: :.::: ...               
XP_016 RGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS         
        250       260       270       280       290                

      410       420       430       440       450       460        
pF1KE0 GDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRK

>>NP_001273006 (OMIM: 616378) UBX domain-containing prot  (297 aa)
 initn: 354 init1: 218 opt: 361  Z-score: 229.1  bits: 51.2 E(85289): 5e-06
Smith-Waterman score: 363; 31.8% identity (59.2% similar) in 255 aa overlap (156-393:43-291)

         130       140       150       160       170       180     
pF1KE0 QSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQ----
                                     :  :  :   .:  :   . . :::.    
NP_001 MGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGL
             20        30        40        50        60        70  

               190       200         210       220        230      
pF1KE0 EPSGCS--DQRPAEDLNIRVERLTKKLE--ERREEKRKEEEQRE-IKKEIERRKTGKEML
       : :: .  . .:: . . : :.  . ::   .....:.:.:.:: ...: .::. :.:. 
NP_001 EGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELS
             80        90       100       110       120       130  

        240       250       260       270       280           290  
pF1KE0 DYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKT----KEEVEA
         ... .:.  .:  ::: :::::. :::.:....:  :.:::: ... .       :  
NP_001 AARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPPVAP
            140       150       160       170       180       190  

            300       310       320       330       340       350  
pF1KE0 AKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQT
         . .  . . :  .::: : .      ::: :::::.:.:. : .   :  .: ..   
NP_001 EPGPVPSSPSQEPPTKRE-YDQ-----CRIQVRLPDGTSLTQTFRAREQLAAVRLYVELH
            200       210             220       230       240      

                360       370       380       390       400        
pF1KE0 VGNTYGN----FSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSS
        :.  :.     .: . :::: :.. :... : .: :.::: ...               
NP_001 RGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS         
        250       260       270       280       290                

      410       420       430       440       450       460        
pF1KE0 GDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRK

>>NP_001273007 (OMIM: 616378) UBX domain-containing prot  (238 aa)
 initn: 345 init1: 209 opt: 338  Z-score: 217.3  bits: 48.7 E(85289): 2.3e-05
Smith-Waterman score: 338; 32.8% identity (63.1% similar) in 198 aa overlap (205-393:41-232)

          180       190       200       210       220        230   
pF1KE0 GHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQRE-IKKEIERRKTGK
                                     .:  .....:.:.:.:: ...: .::. :.
NP_001 IEMGFPRGRAEKALALTGNQGIEAAMDWMLELVAQKQREREEREEREALERERQRRRQGQ
               20        30        40        50        60        70

           240       250       260       270       280             
pF1KE0 EMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKT----KEE
       :.   ... .:.  .:  ::: :::::. :::.:....:  :.:::: ... .       
NP_001 ELSAARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPP
               80        90       100       110       120       130

     290       300       310       320       330       340         
pF1KE0 VEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFA
       :    . .  . . :  .::: : .      ::: :::::.:.:. : .   :  .: ..
NP_001 VAPEPGPVPSSPSQEPPTKRE-YDQ-----CRIQVRLPDGTSLTQTFRAREQLAAVRLYV
              140       150             160       170       180    

     350           360       370       380       390       400     
pF1KE0 AQTVGNTYGN----FSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVH
           :.  :.     .: . :::: :.. :... : .: :.::: ...            
NP_001 ELHRGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS      
          190       200       210       220       230              

         410       420       430       440       450       460     
pF1KE0 SSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREP

>>XP_005274090 (OMIM: 616378) PREDICTED: UBX domain-cont  (312 aa)
 initn: 280 init1: 218 opt: 340  Z-score: 217.1  bits: 49.0 E(85289): 2.4e-05
Smith-Waterman score: 342; 31.5% identity (58.5% similar) in 248 aa overlap (156-386:43-284)

         130       140       150       160       170       180     
pF1KE0 QSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQ----
                                     :  :  :   .:  :   . . :::.    
XP_005 MGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGL
             20        30        40        50        60        70  

               190       200         210       220        230      
pF1KE0 EPSGCS--DQRPAEDLNIRVERLTKKLE--ERREEKRKEEEQRE-IKKEIERRKTGKEML
       : :: .  . .:: . . : :.  . ::   .....:.:.:.:: ...: .::. :.:. 
XP_005 EGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELS
             80        90       100       110       120       130  

        240       250       260       270       280           290  
pF1KE0 DYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKT----KEEVEA
         ... .:.  .:  ::: :::::. :::.:....:  :.:::: ... .       :  
XP_005 AARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPPVAP
            140       150       160       170       180       190  

            300       310       320       330       340       350  
pF1KE0 AKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQT
         . .  . . :  .::: : .      ::: :::::.:.:. : .   :  .: ..   
XP_005 EPGPVPSSPSQEPPTKRE-YDQ-----CRIQVRLPDGTSLTQTFRAREQLAAVRLYVELH
            200       210             220       230       240      

                360       370       380       390       400        
pF1KE0 VGNTYGN----FSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSS
        :.  :.     .: . :::: :.. :... : .: .:                      
XP_005 RGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGMAARLETRTRNWGSREACLGKGGM
        250       260       270       280       290       300      

      410       420       430       440       450       460        
pF1KE0 GDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRK
                                                                   
XP_005 QREGAL                                                      
        310                                                        

>>NP_056937 (OMIM: 616378) UBX domain-containing protein  (312 aa)
 initn: 280 init1: 218 opt: 340  Z-score: 217.1  bits: 49.0 E(85289): 2.4e-05
Smith-Waterman score: 342; 31.5% identity (58.5% similar) in 248 aa overlap (156-386:43-284)

         130       140       150       160       170       180     
pF1KE0 QSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQ----
                                     :  :  :   .:  :   . . :::.    
NP_056 MGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGL
             20        30        40        50        60        70  

               190       200         210       220        230      
pF1KE0 EPSGCS--DQRPAEDLNIRVERLTKKLE--ERREEKRKEEEQRE-IKKEIERRKTGKEML
       : :: .  . .:: . . : :.  . ::   .....:.:.:.:: ...: .::. :.:. 
NP_056 EGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELS
             80        90       100       110       120       130  

        240       250       260       270       280           290  
pF1KE0 DYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKT----KEEVEA
         ... .:.  .:  ::: :::::. :::.:....:  :.:::: ... .       :  
NP_056 AARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPPVAP
            140       150       160       170       180       190  

            300       310       320       330       340       350  
pF1KE0 AKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQT
         . .  . . :  .::: : .      ::: :::::.:.:. : .   :  .: ..   
NP_056 EPGPVPSSPSQEPPTKRE-YDQ-----CRIQVRLPDGTSLTQTFRAREQLAAVRLYVELH
            200       210             220       230       240      

                360       370       380       390       400        
pF1KE0 VGNTYGN----FSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSS
        :.  :.     .: . :::: :.. :... : .: .:                      
NP_056 RGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGMAARLETRTRNWGSREACLGKGGM
        250       260       270       280       290       300      

      410       420       430       440       450       460        
pF1KE0 GDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRK
                                                                   
NP_056 QREGAL                                                      
        310                                                        




508 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 15:45:26 2016 done: Thu Nov  3 15:45:28 2016
 Total Scan time: 11.790 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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