Result of FASTA (ccds) for pF1KE0253
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0253, 392 aa
  1>>>pF1KE0253 392 - 392 aa - 392 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5743+/-0.000936; mu= 14.8632+/- 0.056
 mean_var=59.8218+/-11.941, 0's: 0 Z-trim(104.8): 16  B-trim: 6 in 1/49
 Lambda= 0.165823
 statistics sampled from 8101 (8107) to 8101 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.249), width:  16
 Scan time:  2.470

The best scores are:                                      opt bits E(32554)
CCDS8447.1 PANX3 gene_id:116337|Hs108|chr11        ( 392) 2578 625.3 2.9e-179
CCDS8296.1 PANX1 gene_id:24145|Hs108|chr11         ( 426)  929 230.8 1.8e-60
CCDS54544.1 PANX2 gene_id:56666|Hs108|chr22        ( 643)  528 134.9   2e-31
CCDS14085.2 PANX2 gene_id:56666|Hs108|chr22        ( 677)  528 134.9 2.1e-31


>>CCDS8447.1 PANX3 gene_id:116337|Hs108|chr11             (392 aa)
 initn: 2578 init1: 2578 opt: 2578  Z-score: 3331.7  bits: 625.3 E(32554): 2.9e-179
Smith-Waterman score: 2578; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)

               10        20        30        40        50        60
pF1KE0 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH
              310       320       330       340       350       360

              370       380       390  
pF1KE0 NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
       ::::::::::::::::::::::::::::::::
CCDS84 NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
              370       380       390  

>>CCDS8296.1 PANX1 gene_id:24145|Hs108|chr11              (426 aa)
 initn: 927 init1: 353 opt: 929  Z-score: 1199.1  bits: 230.8 E(32554): 1.8e-60
Smith-Waterman score: 929; 43.3% identity (72.5% similar) in 360 aa overlap (1-355:1-357)

               10        20        30        40        50        60
pF1KE0 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
       :..:. :.::..:: :: .   :..::::::: .:..:  .::: ::::.:::::::.: 
CCDS82 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
       :. :::::::.:: ::::.::: :: .. ..:..  ...    :: :: .:: :: .:.:
CCDS82 GTQISCFSPSSFSWRQAAFVDSYCWAAV-QQKNSLQSESGNLPLWLHKFFPYILLLFAIL
               70        80         90       100       110         

              130       140       150       160          170       
pF1KE0 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHM--LKIRQKS-SDPYVFWNE
       .::: :.:..::.: . ::: ::. :::: :::.:. ..    : .:. . : : :  : 
CCDS82 LYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENL
     120       130       140       150       160       170         

       180         190       200       210       220       230     
pF1KE0 LEKARK--ERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVF
        ..  .  : .:..:..:.::  :. :..:.  :.    : ::.   . .:::..     
CCDS82 GQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSS
     180       190       200       210       220       230         

         240       250       260       270       280       290     
pF1KE0 FQEEFSCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLC
       ...:: ::::.:.: ... ::. . :.: ...:::..:. ....:..:.::..:.:    
CCDS82 LSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPF
     240       250       260       270       280       290         

         300       310       320       330       340       350     
pF1KE0 RWDKRLLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDT
       :    .:.:::.::.::.:  :  :   :::..  :::. ::::. :.. :.::  .:..
CCDS82 RQKTDVLKVYEILPTFDVLHFKSEG--YNDLSLYNLFLEENISEVKSYKCLKVLENIKSS
     300       310       320         330       340       350       

         360       370       380       390                         
pF1KE0 TTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP                       
                                                                   
CCDS82 GQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNA
       360       370       380       390       400       410       

>>CCDS54544.1 PANX2 gene_id:56666|Hs108|chr22             (643 aa)
 initn: 370 init1: 119 opt: 528  Z-score: 677.7  bits: 134.9 E(32554): 2e-31
Smith-Waterman score: 528; 30.4% identity (60.0% similar) in 395 aa overlap (1-378:11-389)

                         10            20           30        40   
pF1KE0           MSLAHTAAEYMLSDALLP----DRRGPR---LKGLRLELPLDRIVKFVAV
                 :. :  :.:  : . .::    :. :     :  :.::::.::.: . .:
CCDS54 MHHLLEQSADMATALLAGEK-LRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTV
               10        20         30        40        50         

            50        60        70        80        90       100   
pF1KE0 GSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKS
         :.::..:.:...:.   :: :..: ::.  :: :. . ::  :   ..  :: :   :
CCDS54 LVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTEL---RDALPGVDA--S
      60        70         80        90       100          110     

               110       120       130       140       150         
pF1KE0 LWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQ
       :::    :: :::.:::.: .::.:.: :.. :   :.:.: :...:.:. :.:. .   
CCDS54 LWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRA
           120       130       140       150       160       170   

     160       170           180       190       200       210     
pF1KE0 HMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACKQRSHSLVATYLLRNSL
         .. . .:. : .   :    .:.:.::.  :  :.:.::  . ::. :.  :: :. :
CCDS54 PKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVL
           180       190       200       210       220       230   

         220       230       240       250        260       270    
pF1KE0 LLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL-ITCRLTSLSIFQIVSL
       .:.....   ::  ..  .  :.::.:.. ..  .     : . ..:.: :... .:.. 
CCDS54 ILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAG
           240       250        260       270       280       290  

          280       290       300       310       320        330   
pF1KE0 SSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKMLG-CPINDLNVILLFL
        ....  ..  .:. :: .:  . :  . ... :    . .:..     . :.:.. .: 
CCDS54 VDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQWRRSQFCDINILAMFC
            300       310       320        330       340       350 

           340       350       360       370       380       390   
pF1KE0 RANISELISFSWLSVLCVLKDTTTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP 
         : ... :.. :. .   .:        :.::    :::.:  :               
CCDS54 NENRDHIKSLNRLDFITNESDLM-----YDNVVR--QLLAALAQSNHDATPTVRDSGVQT
             360       370            380         390       400    

CCDS54 VDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPAR
          410       420       430       440       450       460    

>>CCDS14085.2 PANX2 gene_id:56666|Hs108|chr22             (677 aa)
 initn: 370 init1: 119 opt: 528  Z-score: 677.3  bits: 134.9 E(32554): 2.1e-31
Smith-Waterman score: 528; 30.4% identity (60.0% similar) in 395 aa overlap (1-378:11-389)

                         10            20           30        40   
pF1KE0           MSLAHTAAEYMLSDALLP----DRRGPR---LKGLRLELPLDRIVKFVAV
                 :. :  :.:  : . .::    :. :     :  :.::::.::.: . .:
CCDS14 MHHLLEQSADMATALLAGEK-LRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTV
               10        20         30        40        50         

            50        60        70        80        90       100   
pF1KE0 GSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKS
         :.::..:.:...:.   :: :..: ::.  :: :. . ::  :   ..  :: :   :
CCDS14 LVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTEL---RDALPGVDA--S
      60        70         80        90       100          110     

               110       120       130       140       150         
pF1KE0 LWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQ
       :::    :: :::.:::.: .::.:.: :.. :   :.:.: :...:.:. :.:. .   
CCDS14 LWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRA
           120       130       140       150       160       170   

     160       170           180       190       200       210     
pF1KE0 HMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACKQRSHSLVATYLLRNSL
         .. . .:. : .   :    .:.:.::.  :  :.:.::  . ::. :.  :: :. :
CCDS14 PKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVL
           180       190       200       210       220       230   

         220       230       240       250        260       270    
pF1KE0 LLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL-ITCRLTSLSIFQIVSL
       .:.....   ::  ..  .  :.::.:.. ..  .     : . ..:.: :... .:.. 
CCDS14 ILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAG
           240       250        260       270       280       290  

          280       290       300       310       320        330   
pF1KE0 SSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKMLG-CPINDLNVILLFL
        ....  ..  .:. :: .:  . :  . ... :    . .:..     . :.:.. .: 
CCDS14 VDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQWRRSQFCDINILAMFC
            300       310       320        330       340       350 

           340       350       360       370       380       390   
pF1KE0 RANISELISFSWLSVLCVLKDTTTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP 
         : ... :.. :. .   .:        :.::    :::.:  :               
CCDS14 NENRDHIKSLNRLDFITNESDLM-----YDNVVR--QLLAALAQSNHDATPTVRDSGVQT
             360       370            380         390       400    

CCDS14 VDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPAR
          410       420       430       440       450       460    




392 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:57:05 2016 done: Thu Nov  3 18:57:05 2016
 Total Scan time:  2.470 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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