Result of FASTA (omim) for pF1KE0238
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0238, 162 aa
  1>>>pF1KE0238 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0018+/-0.000359; mu= 13.1086+/- 0.022
 mean_var=57.4511+/-12.064, 0's: 0 Z-trim(113.1): 32  B-trim: 1242 in 1/49
 Lambda= 0.169210
 statistics sampled from 22279 (22311) to 22279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.262), width:  16
 Scan time:  5.440

The best scores are:                                      opt bits E(85289)
NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [H ( 162) 1034 260.5 8.8e-70
XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like s ( 195) 1017 256.3 1.8e-68
XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like s ( 162)  728 185.8 2.7e-47
NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 ( 162)  728 185.8 2.7e-47
NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [H ( 162)  728 185.8 2.7e-47
XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like s ( 177)  728 185.8 2.9e-47
NP_004576 (OMIM: 605092) retinoic acid receptor re ( 164)  527 136.7 1.6e-32
XP_016862412 (OMIM: 606487) PREDICTED: phospholipi ( 168)  467 122.0 4.2e-28
NP_065119 (OMIM: 606487) phospholipid-metabolizing ( 273)  467 122.2 6.4e-28
XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159)  457 119.6 2.2e-27
XP_011543055 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159)  457 119.6 2.2e-27
XP_011543053 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 268)  457 119.7 3.4e-27
NP_001140201 (OMIM: 611474) Ca(2+)-independent N-a ( 269)  457 119.7 3.4e-27
NP_473449 (OMIM: 611474) Ca(2+)-independent N-acyl ( 279)  457 119.7 3.5e-27
XP_011511337 (OMIM: 606487) PREDICTED: phospholipi ( 339)  439 115.4 8.7e-26
XP_011511336 (OMIM: 606487) PREDICTED: phospholipi ( 342)  439 115.4 8.8e-26
NP_001140200 (OMIM: 611474) Ca(2+)-independent N-a ( 253)  351 93.8   2e-19
XP_011543054 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 167)  283 77.1 1.4e-14
NP_001288574 (OMIM: 268000,604863,613341) lecithin ( 230)  149 44.5 0.00013
NP_004735 (OMIM: 268000,604863,613341) lecithin re ( 230)  149 44.5 0.00013


>>NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [Homo   (162 aa)
 initn: 1034 init1: 1034 opt: 1034  Z-score: 1373.8  bits: 260.5 E(85289): 8.8e-70
Smith-Waterman score: 1034; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
       ::::::::::::::::::::::::::::::::::::::::::
NP_060 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
              130       140       150       160  

>>XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like suppr  (195 aa)
 initn: 1017 init1: 1017 opt: 1017  Z-score: 1350.1  bits: 256.3 E(85289): 1.8e-68
Smith-Waterman score: 1017; 100.0% identity (100.0% similar) in 159 aa overlap (4-162:37-195)

                                          10        20        30   
pF1KE0                            MALARPRPRLGDLIEISRFGYAHWAIYVGDGYV
                                     ::::::::::::::::::::::::::::::
XP_011 SQRVFQFWLQSICIPTLKLFVCLFVYSLKRARPRPRLGDLIEISRFGYAHWAIYVGDGYV
         10        20        30        40        50        60      

            40        50        60        70        80        90   
pF1KE0 VHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIV
         70        80        90       100       110       120      

           100       110       120       130       140       150   
pF1KE0 KRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGIL
        130       140       150       160       170       180      

           160  
pF1KE0 LARSKRERQ
       :::::::::
XP_011 LARSKRERQ
        190     

>>XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like suppr  (162 aa)
 initn: 729 init1: 709 opt: 728  Z-score: 970.1  bits: 185.8 E(85289): 2.7e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)

               10        20        30        40        50        60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
            :.:. :::::: :  : :::::::::::::::: ::.::::::::.::::.::::
XP_006 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
       :::::  :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
XP_006 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
       ::::.:::::  .. ...::.  ::: ::.:....:.::..:
XP_006 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160  

>>NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 [Ho  (162 aa)
 initn: 729 init1: 709 opt: 728  Z-score: 970.1  bits: 185.8 E(85289): 2.7e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)

               10        20        30        40        50        60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
            :.:. :::::: :  : :::::::::::::::: ::.::::::::.::::.::::
NP_001 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
       :::::  :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
NP_001 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
       ::::.:::::  .. ...::.  ::: ::.:....:.::..:
NP_001 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160  

>>NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [Homo   (162 aa)
 initn: 729 init1: 709 opt: 728  Z-score: 970.1  bits: 185.8 E(85289): 2.7e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)

               10        20        30        40        50        60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
            :.:. :::::: :  : :::::::::::::::: ::.::::::::.::::.::::
NP_009 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
       :::::  :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
NP_009 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
       ::::.:::::  .. ...::.  ::: ::.:....:.::..:
NP_009 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160  

>>XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like suppr  (177 aa)
 initn: 729 init1: 709 opt: 728  Z-score: 969.5  bits: 185.8 E(85289): 2.9e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:21-177)

                              10        20        30        40     
pF1KE0                MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGA
                           :.:. :::::: :  : :::::::::::::::: ::.:::
XP_011 MKTQRSSWCQLLLHRIGQRIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE0 GAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELP
       :::::.::::.:::::::::  :::.:.:.:::::::.:.::: .::..:::::::::. 
XP_011 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
               70        80        90       100       110       120

         110       120       130       140       150       160  
pF1KE0 YSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
       :.:::.:::::::.:::::.:::::  .. ...::.  ::: ::.:....:.::..:
XP_011 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160       170       

>>NP_004576 (OMIM: 605092) retinoic acid receptor respon  (164 aa)
 initn: 526 init1: 526 opt: 527  Z-score: 704.8  bits: 136.7 E(85289): 1.6e-32
Smith-Waterman score: 527; 55.7% identity (77.9% similar) in 149 aa overlap (1-147:1-149)

               10        20        30        40        50        60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
       ::  . .:. :::::: :.:: :::.:.:::::.:::: ::  :::..::.:.:.:.: :
NP_004 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
       :.: :  :.::  :::::. : .: : : . :.. :.:.:::.. ::..: ::::::..:
NP_004 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
               70        80        90       100       110       120

              130       140         150       160  
pF1KE0 RYGVSRSDQVTGAVTTVGVAA--GLLAAASLVGILLARSKRERQ
       ::: ::  ::  : . ::::.  :.:..:               
NP_004 RYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
              130       140       150       160    

>>XP_016862412 (OMIM: 606487) PREDICTED: phospholipid-me  (168 aa)
 initn: 449 init1: 310 opt: 467  Z-score: 625.5  bits: 122.0 E(85289): 4.2e-28
Smith-Waterman score: 467; 45.3% identity (78.9% similar) in 161 aa overlap (2-161:8-166)

                      10        20        30        40        50   
pF1KE0       MALARP-RPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSA
              .:  :  :  :::::. : :: :::.:.:::::...::.. :  :. .:. :.
XP_016 MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSV
               10        20        30        40        50          

            60        70        80        90       100       110   
pF1KE0 LTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNC
       ...::.:: .::. :.:.:.::.:::.:. : ::: ..:.::.: ..:::. :.:  .::
XP_016 FSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNC
      60        70        80        90       100       110         

           120       130       140       150       160   
pF1KE0 EHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ 
       ::::. :::: . :.:.. :..::  ... ... :..: :. ...: .  
XP_016 EHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAKYY
     120       130       140       150        160        

>>NP_065119 (OMIM: 606487) phospholipid-metabolizing enz  (273 aa)
 initn: 473 init1: 310 opt: 467  Z-score: 622.3  bits: 122.2 E(85289): 6.4e-28
Smith-Waterman score: 467; 45.3% identity (78.9% similar) in 161 aa overlap (2-161:113-271)

                                             10        20        30
pF1KE0                              MALARP-RPRLGDLIEISRFGYAHWAIYVGD
                                     .:  :  :  :::::. : :: :::.:.::
NP_065 PRETPGHTQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGD
             90       100       110       120       130       140  

               40        50        60        70        80        90
pF1KE0 GYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSN
       :::...::.. :  :. .:. :....::.:: .::. :.:.:.::.:::.:. : ::: .
NP_065 GYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVE
            150        160       170       180       190       200 

              100       110       120       130       140       150
pF1KE0 KIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLV
       .:.::.: ..:::. :.:  .::::::. :::: . :.:.. :..::  ... ... :..
NP_065 EIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFL
             210       220       230       240       250       260 

              160   
pF1KE0 GILLARSKRERQ 
       : :. ...: .  
NP_065 G-LFPKGQRAKYY
              270   

>>XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-independ  (159 aa)
 initn: 425 init1: 249 opt: 457  Z-score: 612.6  bits: 119.6 E(85289): 2.2e-27
Smith-Waterman score: 457; 51.4% identity (71.2% similar) in 146 aa overlap (2-147:4-147)

                 10        20        30        40        50        
pF1KE0   MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKA
          ....:::: :::::: :.:: :::::: :  :::::: ::   .:  :. : ..:.:
XP_016 MSRSVGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRA
               10        20        30        40          50        

       60        70        80        90       100       110        
pF1KE0 IVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVN
       .::   :  :  : ...:::: :  : ::: .::..:....:.. . :::   :::::::
XP_016 VVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVN
       60        70        80        90       100       110        

      120       130       140       150       160  
pF1KE0 HLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
        ::::: ::.::  :.   . ::: . .:               
XP_016 GLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPKPITA   
      120       130       140       150            




162 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 19:53:33 2016 done: Thu Nov  3 19:53:34 2016
 Total Scan time:  5.440 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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