Result of FASTA (omim) for pF1KB6518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6518, 386 aa
  1>>>pF1KB6518 386 - 386 aa - 386 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5757+/-0.000306; mu= 6.9971+/- 0.019
 mean_var=147.8779+/-30.517, 0's: 0 Z-trim(122.1): 323  B-trim: 1529 in 2/59
 Lambda= 0.105468
 statistics sampled from 39143 (39602) to 39143 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.464), width:  16
 Scan time:  9.490

The best scores are:                                      opt bits E(85289)
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 2626 410.8 2.8e-114
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 2626 410.8 2.8e-114
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 2626 410.8 2.8e-114
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386) 2626 410.8 2.8e-114
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 2607 407.9 2.1e-113
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 2030 320.1 5.6e-87
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 2011 317.2 4.1e-86
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 1616 257.1 5.6e-68
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 1616 257.1 5.6e-68
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 1616 257.1 5.6e-68
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 1616 257.1 6.2e-68
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 1614 256.8 6.8e-68
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 1614 256.8 6.8e-68
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 1614 256.8 6.8e-68
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 1614 256.8 7.6e-68
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 1593 253.6 6.3e-67
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 1593 253.6 6.3e-67
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 1593 253.6 6.3e-67
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 1587 252.7 1.2e-66
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 1587 252.7 1.2e-66
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 1587 252.7 1.2e-66
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 1587 252.7 1.2e-66
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 1587 252.7 1.2e-66
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo  ( 425)  972 159.1 1.8e-38
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425)  972 159.1 1.8e-38
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443)  972 159.1 1.8e-38
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491)  940 154.3 5.8e-37
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492)  940 154.3 5.8e-37
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535)  940 154.3 6.2e-37
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564)  940 154.3 6.5e-37
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567)  940 154.3 6.5e-37
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  908 149.5   2e-35
XP_011525693 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  908 149.5   2e-35
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  908 149.5   2e-35
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  908 149.5   2e-35
NP_115674 (OMIM: 600327) synaptotagmin-3 [Homo sap ( 590)  908 149.5   2e-35
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293)  894 147.1 4.9e-35
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403)  894 147.2 6.3e-35
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409)  894 147.2 6.4e-35
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447)  894 147.3 6.9e-35
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449)  894 147.3 6.9e-35
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453)  894 147.3 6.9e-35
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478)  894 147.3 7.2e-35
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484)  894 147.3 7.3e-35
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528)  894 147.3 7.8e-35
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611)  894 147.4 8.8e-35
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617)  894 147.4 8.9e-35
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642)  894 147.4 9.2e-35
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648)  894 147.4 9.2e-35
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651)  894 147.4 9.3e-35


>>XP_016882665 (OMIM: 600782) PREDICTED: synaptotagmin-5  (386 aa)
 initn: 2626 init1: 2626 opt: 2626  Z-score: 2172.6  bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)

               10        20        30        40        50        60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
              310       320       330       340       350       360

              370       380      
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
       ::::::::::::::::::::::::::
XP_016 LANPRRPIAQWHSLRPPDRVRLLPAP
              370       380      

>>XP_016882664 (OMIM: 600782) PREDICTED: synaptotagmin-5  (386 aa)
 initn: 2626 init1: 2626 opt: 2626  Z-score: 2172.6  bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)

               10        20        30        40        50        60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
              310       320       330       340       350       360

              370       380      
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
       ::::::::::::::::::::::::::
XP_016 LANPRRPIAQWHSLRPPDRVRLLPAP
              370       380      

>>XP_006723402 (OMIM: 600782) PREDICTED: synaptotagmin-5  (386 aa)
 initn: 2626 init1: 2626 opt: 2626  Z-score: 2172.6  bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)

               10        20        30        40        50        60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
              310       320       330       340       350       360

              370       380      
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
       ::::::::::::::::::::::::::
XP_006 LANPRRPIAQWHSLRPPDRVRLLPAP
              370       380      

>>NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 [Ho  (386 aa)
 initn: 2626 init1: 2626 opt: 2626  Z-score: 2172.6  bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)

               10        20        30        40        50        60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
              310       320       330       340       350       360

              370       380      
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
       ::::::::::::::::::::::::::
NP_003 LANPRRPIAQWHSLRPPDRVRLLPAP
              370       380      

>>XP_006723403 (OMIM: 600782) PREDICTED: synaptotagmin-5  (385 aa)
 initn: 1626 init1: 1626 opt: 2607  Z-score: 2157.0  bits: 407.9 E(85289): 2.1e-113
Smith-Waterman score: 2607; 99.7% identity (99.7% similar) in 386 aa overlap (1-386:1-385)

               10        20        30        40        50        60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_006 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREE-EKL
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
     300       310       320       330       340       350         

              370       380      
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
       ::::::::::::::::::::::::::
XP_006 LANPRRPIAQWHSLRPPDRVRLLPAP
     360       370       380     

>>XP_006723404 (OMIM: 600782) PREDICTED: synaptotagmin-5  (383 aa)
 initn: 2046 init1: 2025 opt: 2030  Z-score: 1682.5  bits: 320.1 E(85289): 5.6e-87
Smith-Waterman score: 2030; 84.1% identity (88.9% similar) in 377 aa overlap (17-386:7-383)

               10        20         30        40            50     
pF1KB6 MFPEPPTPGPPSPDTPPDSSRI-SHGPVPPWALATIVLVSGLLIFS----CCFCLYRKSC
                       : :.:. .. :   :.    : ..: : .        :: ::. 
XP_006           MTRGGCPVSARLFAQRPHGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDS
                         10        20        30        40        50

            60        70        80        90       100       110   
pF1KB6 RRRT--GKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQ
       :     ... : ..  .  ..     :   .:::::::::::::::::::::::::::::
XP_006 RTPPPCSRSPQPRGLHRPTRLPTPVASATAQVQPEVEELEPAPSGPGQQVADKHELGRLQ
               60        70        80        90       100       110

           120       130       140       150       160       170   
pF1KB6 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
              120       130       140       150       160       170

           180       190       200       210       220       230   
pF1KB6 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
              180       190       200       210       220       230

           240       250       260       270       280       290   
pF1KB6 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
              240       250       260       270       280       290

           300       310       320       330       340       350   
pF1KB6 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
              300       310       320       330       340       350

           360       370       380      
pF1KB6 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
       :::::::::::::::::::::::::::::::::
XP_006 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
              360       370       380   

>>NP_001284703 (OMIM: 600782) synaptotagmin-5 isoform 2   (382 aa)
 initn: 1046 init1: 1025 opt: 2011  Z-score: 1666.9  bits: 317.2 E(85289): 4.1e-86
Smith-Waterman score: 2011; 83.8% identity (88.6% similar) in 377 aa overlap (17-386:7-382)

               10        20         30        40            50     
pF1KB6 MFPEPPTPGPPSPDTPPDSSRI-SHGPVPPWALATIVLVSGLLIFS----CCFCLYRKSC
                       : :.:. .. :   :.    : ..: : .        :: ::. 
NP_001           MTRGGCPVSARLFAQRPHGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDS
                         10        20        30        40        50

            60        70        80        90       100       110   
pF1KB6 RRRT--GKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQ
       :     ... : ..  .  ..     :   .:::::::::::::::::::::::::::::
NP_001 RTPPPCSRSPQPRGLHRPTRLPTPVASATAQVQPEVEELEPAPSGPGQQVADKHELGRLQ
               60        70        80        90       100       110

           120       130       140       150       160       170   
pF1KB6 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
              120       130       140       150       160       170

           180       190       200       210       220       230   
pF1KB6 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
              180       190       200       210       220       230

           240       250       260       270       280       290   
pF1KB6 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
       ::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REE-EKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
               240       250       260       270       280         

           300       310       320       330       340       350   
pF1KB6 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
     290       300       310       320       330       340         

           360       370       380      
pF1KB6 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
       :::::::::::::::::::::::::::::::::
NP_001 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
     350       360       370       380  

>>XP_011507494 (OMIM: 600104,616040) PREDICTED: synaptot  (422 aa)
 initn: 1829 init1: 1436 opt: 1616  Z-score: 1341.5  bits: 257.1 E(85289): 5.6e-68
Smith-Waterman score: 1616; 61.6% identity (86.8% similar) in 365 aa overlap (20-383:53-417)

                          10        20        30        40         
pF1KB6            MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC
                                     ..:.. :.::::: .:..:.:::...::::
XP_011 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC
             30        40        50        60        70        80  

      50         60        70        80        90       100        
pF1KB6 LYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       . .: : ... .:: ..... . ...: .  . . . . ..:       : :..  . ..
XP_011 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQLPQDDDDAETGLTEGEGEGEEEKEPEN
             90       100       110       120       130       140  

      110       120       130       140       150       160        
pF1KB6 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT
       ::.::.:::::::..:: ::.:::  : :::.::.:::::.:.:::::...:::::::.:
XP_011 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT
            150       160       170       180       190       200  

      170       180       190       200       210       220        
pF1KB6 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRE
       ::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. ::.
XP_011 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRD
            210       220       230       240       250       260  

      230       240       250       260       270       280        
pF1KB6 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK
       ::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.:.::
XP_011 LQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK
            270       280       290       300       310       320  

      290       300       310       320       330       340        
pF1KB6 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAA
       ...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. ::. 
XP_011 RLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSN
            330       340       350       360       370       380  

      350       360       370       380        
pF1KB6 AGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP  
       : :. ::::.::::::::::::::::.: ..:  :     
XP_011 ATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
            390       400       410       420  

>>XP_016855800 (OMIM: 600104,616040) PREDICTED: synaptot  (422 aa)
 initn: 1829 init1: 1436 opt: 1616  Z-score: 1341.5  bits: 257.1 E(85289): 5.6e-68
Smith-Waterman score: 1616; 61.6% identity (86.8% similar) in 365 aa overlap (20-383:53-417)

                          10        20        30        40         
pF1KB6            MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC
                                     ..:.. :.::::: .:..:.:::...::::
XP_016 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC
             30        40        50        60        70        80  

      50         60        70        80        90       100        
pF1KB6 LYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       . .: : ... .:: ..... . ...: .  . . . . ..:       : :..  . ..
XP_016 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQLPQDDDDAETGLTEGEGEGEEEKEPEN
             90       100       110       120       130       140  

      110       120       130       140       150       160        
pF1KB6 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT
       ::.::.:::::::..:: ::.:::  : :::.::.:::::.:.:::::...:::::::.:
XP_016 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT
            150       160       170       180       190       200  

      170       180       190       200       210       220        
pF1KB6 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRE
       ::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. ::.
XP_016 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRD
            210       220       230       240       250       260  

      230       240       250       260       270       280        
pF1KB6 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK
       ::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.:.::
XP_016 LQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK
            270       280       290       300       310       320  

      290       300       310       320       330       340        
pF1KB6 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAA
       ...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. ::. 
XP_016 RLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSN
            330       340       350       360       370       380  

      350       360       370       380        
pF1KB6 AGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP  
       : :. ::::.::::::::::::::::.: ..:  :     
XP_016 ATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
            390       400       410       420  

>>XP_016855801 (OMIM: 600104,616040) PREDICTED: synaptot  (422 aa)
 initn: 1829 init1: 1436 opt: 1616  Z-score: 1341.5  bits: 257.1 E(85289): 5.6e-68
Smith-Waterman score: 1616; 61.6% identity (86.8% similar) in 365 aa overlap (20-383:53-417)

                          10        20        30        40         
pF1KB6            MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC
                                     ..:.. :.::::: .:..:.:::...::::
XP_016 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC
             30        40        50        60        70        80  

      50         60        70        80        90       100        
pF1KB6 LYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       . .: : ... .:: ..... . ...: .  . . . . ..:       : :..  . ..
XP_016 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQLPQDDDDAETGLTEGEGEGEEEKEPEN
             90       100       110       120       130       140  

      110       120       130       140       150       160        
pF1KB6 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT
       ::.::.:::::::..:: ::.:::  : :::.::.:::::.:.:::::...:::::::.:
XP_016 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT
            150       160       170       180       190       200  

      170       180       190       200       210       220        
pF1KB6 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRE
       ::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. ::.
XP_016 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRD
            210       220       230       240       250       260  

      230       240       250       260       270       280        
pF1KB6 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK
       ::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.:.::
XP_016 LQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK
            270       280       290       300       310       320  

      290       300       310       320       330       340        
pF1KB6 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAA
       ...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. ::. 
XP_016 RLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSN
            330       340       350       360       370       380  

      350       360       370       380        
pF1KB6 AGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP  
       : :. ::::.::::::::::::::::.: ..:  :     
XP_016 ATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
            390       400       410       420  




386 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:09:07 2016 done: Fri Nov  4 17:09:08 2016
 Total Scan time:  9.490 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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