Result of FASTA (omim) for pF1KB9792
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9792, 210 aa
  1>>>pF1KB9792 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1580+/-0.000338; mu= 6.7527+/- 0.021
 mean_var=156.1088+/-30.962, 0's: 0 Z-trim(119.5): 73  B-trim: 243 in 1/55
 Lambda= 0.102650
 statistics sampled from 33432 (33509) to 33432 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.393), width:  16
 Scan time:  6.540

The best scores are:                                      opt bits E(85289)
NP_937861 (OMIM: 275355,601566) inhibitor of growt ( 210) 1444 224.8 8.1e-59
NP_937860 (OMIM: 275355,601566) inhibitor of growt ( 235) 1444 224.8 8.8e-59
NP_001254657 (OMIM: 275355,601566) inhibitor of gr ( 262) 1444 224.9 9.5e-59
NP_937862 (OMIM: 275355,601566) inhibitor of growt ( 279) 1444 224.9   1e-58
NP_005528 (OMIM: 275355,601566) inhibitor of growt ( 422) 1444 225.1 1.3e-58
XP_011530229 (OMIM: 604215) PREDICTED: inhibitor o ( 225)  704 115.2 8.3e-26
NP_001278888 (OMIM: 604215) inhibitor of growth pr ( 240)  704 115.2 8.7e-26
NP_001555 (OMIM: 604215) inhibitor of growth prote ( 280)  704 115.3 9.7e-26
XP_005253755 (OMIM: 608524) PREDICTED: inhibitor o ( 200)  502 85.3 7.7e-17
XP_011519267 (OMIM: 608524) PREDICTED: inhibitor o ( 222)  502 85.3 8.3e-17
NP_001121057 (OMIM: 608524) inhibitor of growth pr ( 225)  502 85.3 8.4e-17
NP_001121054 (OMIM: 608524) inhibitor of growth pr ( 249)  502 85.3 9.1e-17
NP_001121055 (OMIM: 608524) inhibitor of growth pr ( 246)  428 74.4 1.8e-13
XP_016874882 (OMIM: 608524) PREDICTED: inhibitor o ( 196)  422 73.4 2.8e-13
XP_016874881 (OMIM: 608524) PREDICTED: inhibitor o ( 199)  422 73.4 2.8e-13
XP_011519266 (OMIM: 608524) PREDICTED: inhibitor o ( 224)  422 73.5 3.1e-13
NP_001121056 (OMIM: 608524) inhibitor of growth pr ( 245)  422 73.5 3.3e-13
NP_057246 (OMIM: 608524) inhibitor of growth prote ( 248)  422 73.5 3.3e-13
NP_115705 (OMIM: 608525) inhibitor of growth prote ( 240)  416 72.6   6e-13
XP_016860586 (OMIM: 608525) PREDICTED: inhibitor o ( 300)  416 72.7 7.1e-13
NP_061944 (OMIM: 607493) inhibitor of growth prote ( 418)  408 71.6 2.1e-12
NP_001317091 (OMIM: 608525) inhibitor of growth pr ( 226)  351 62.9 4.5e-10
XP_016860588 (OMIM: 608525) PREDICTED: inhibitor o ( 286)  351 63.0 5.4e-10
XP_016860587 (OMIM: 608525) PREDICTED: inhibitor o ( 286)  351 63.0 5.4e-10


>>NP_937861 (OMIM: 275355,601566) inhibitor of growth pr  (210 aa)
 initn: 1444 init1: 1444 opt: 1444  Z-score: 1177.0  bits: 224.8 E(85289): 8.1e-59
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)

               10        20        30        40        50        60
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG
              130       140       150       160       170       180

              190       200       210
pF1KB9 KWYCPKCRGENEKTMDKALEKSKKERAYNR
       ::::::::::::::::::::::::::::::
NP_937 KWYCPKCRGENEKTMDKALEKSKKERAYNR
              190       200       210

>>NP_937860 (OMIM: 275355,601566) inhibitor of growth pr  (235 aa)
 initn: 1444 init1: 1444 opt: 1444  Z-score: 1176.3  bits: 224.8 E(85289): 8.8e-59
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:26-235)

                                        10        20        30     
pF1KB9                          MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTR
                                :::::::::::::::::::::::::::::::::::
NP_937 MEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTR
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KB9 QVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 QVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASS
               70        80        90       100       110       120

         100       110       120       130       140       150     
pF1KB9 NHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 NHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMI
              130       140       150       160       170       180

         160       170       180       190       200       210
pF1KB9 GCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 GCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
              190       200       210       220       230     

>>NP_001254657 (OMIM: 275355,601566) inhibitor of growth  (262 aa)
 initn: 1444 init1: 1444 opt: 1444  Z-score: 1175.7  bits: 224.9 E(85289): 9.5e-59
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:53-262)

                                             10        20        30
pF1KB9                               MLHCVQRALIRSQELGDEKIQIVSQMVELV
                                     ::::::::::::::::::::::::::::::
NP_001 GPSAITEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELV
             30        40        50        60        70        80  

               40        50        60        70        80        90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
             90       100       110       120       130       140  

              100       110       120       130       140       150
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
            150       160       170       180       190       200  

              160       170       180       190       200       210
pF1KB9 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
            210       220       230       240       250       260  

>>NP_937862 (OMIM: 275355,601566) inhibitor of growth pr  (279 aa)
 initn: 1444 init1: 1444 opt: 1444  Z-score: 1175.3  bits: 224.9 E(85289): 1e-58
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:70-279)

                                             10        20        30
pF1KB9                               MLHCVQRALIRSQELGDEKIQIVSQMVELV
                                     ::::::::::::::::::::::::::::::
NP_937 IDAKYQEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELV
      40        50        60        70        80        90         

               40        50        60        70        80        90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
     100       110       120       130       140       150         

              100       110       120       130       140       150
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
     160       170       180       190       200       210         

              160       170       180       190       200       210
pF1KB9 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
     220       230       240       250       260       270         

>>NP_005528 (OMIM: 275355,601566) inhibitor of growth pr  (422 aa)
 initn: 1444 init1: 1444 opt: 1444  Z-score: 1173.0  bits: 225.1 E(85289): 1.3e-58
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:213-422)

                                             10        20        30
pF1KB9                               MLHCVQRALIRSQELGDEKIQIVSQMVELV
                                     ::::::::::::::::::::::::::::::
NP_005 RAWPWKQILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELV
            190       200       210       220       230       240  

               40        50        60        70        80        90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
            250       260       270       280       290       300  

              100       110       120       130       140       150
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
            310       320       330       340       350       360  

              160       170       180       190       200       210
pF1KB9 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
            370       380       390       400       410       420  

>>XP_011530229 (OMIM: 604215) PREDICTED: inhibitor of gr  (225 aa)
 initn: 836 init1: 662 opt: 704  Z-score: 584.3  bits: 115.2 E(85289): 8.3e-26
Smith-Waterman score: 849; 62.4% identity (81.7% similar) in 202 aa overlap (5-206:31-222)

                                         10        20        30    
pF1KB9                           MLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
                                     .::::: ::::::::::::.::.::::::.
XP_011 MNETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRA
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB9 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
       ::.. : . :   :. ...   : ::  :      ..: .. .:.: ::::..:.:.   
XP_011 RQMELHSQCF---QDPAESERASDKAKMD------SSQPER-SSRRPRRQRTSESRDLCH
               70           80              90        100       110

          100       110       120       130       140       150    
pF1KB9 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
         .  .:  .  :::::.:..::::::::: ::::::... :::::::::::::::::::
XP_011 MANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEM
              120       130       140       150       160       170

          160       170       180       190       200       210
pF1KB9 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       :::::..:::::::::::.:..:::::::::::::.:::::::. ::.::.:    
XP_011 IGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR 
              180       190       200       210       220      

>>NP_001278888 (OMIM: 604215) inhibitor of growth protei  (240 aa)
 initn: 836 init1: 662 opt: 704  Z-score: 583.9  bits: 115.2 E(85289): 8.7e-26
Smith-Waterman score: 849; 62.4% identity (81.7% similar) in 202 aa overlap (5-206:46-237)

                                         10        20        30    
pF1KB9                           MLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
                                     .::::: ::::::::::::.::.::::::.
NP_001 APQTLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRA
          20        30        40        50        60        70     

           40        50        60        70        80        90    
pF1KB9 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
       ::.. : . :   :. ...   : ::  :      ..: .. .:.: ::::..:.:.   
NP_001 RQMELHSQCF---QDPAESERASDKAKMD------SSQPER-SSRRPRRQRTSESRDLCH
          80           90       100              110       120     

          100       110       120       130       140       150    
pF1KB9 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
         .  .:  .  :::::.:..::::::::: ::::::... :::::::::::::::::::
NP_001 MANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEM
         130       140       150       160       170       180     

          160       170       180       190       200       210
pF1KB9 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       :::::..:::::::::::.:..:::::::::::::.:::::::. ::.::.:    
NP_001 IGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR 
         190       200       210       220       230       240 

>>NP_001555 (OMIM: 604215) inhibitor of growth protein 2  (280 aa)
 initn: 836 init1: 662 opt: 704  Z-score: 583.1  bits: 115.3 E(85289): 9.7e-26
Smith-Waterman score: 849; 62.4% identity (81.7% similar) in 202 aa overlap (5-206:86-277)

                                         10        20        30    
pF1KB9                           MLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
                                     .::::: ::::::::::::.::.::::::.
NP_001 YQETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRA
          60        70        80        90       100       110     

           40        50        60        70        80        90    
pF1KB9 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
       ::.. : . :   :. ...   : ::  :      ..: .. .:.: ::::..:.:.   
NP_001 RQMELHSQCF---QDPAESERASDKAKMD------SSQPER-SSRRPRRQRTSESRDLCH
         120          130       140              150       160     

          100       110       120       130       140       150    
pF1KB9 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
         .  .:  .  :::::.:..::::::::: ::::::... :::::::::::::::::::
NP_001 MANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEM
         170       180       190       200       210       220     

          160       170       180       190       200       210
pF1KB9 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       :::::..:::::::::::.:..:::::::::::::.:::::::. ::.::.:    
NP_001 IGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR 
         230       240       250       260       270       280 

>>XP_005253755 (OMIM: 608524) PREDICTED: inhibitor of gr  (200 aa)
 initn: 511 init1: 368 opt: 502  Z-score: 423.3  bits: 85.3 E(85289): 7.7e-17
Smith-Waterman score: 502; 38.5% identity (68.7% similar) in 195 aa overlap (1-193:15-199)

                             10        20        30        40      
pF1KB9               MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEA
                     .:. .:.:  . .:.::.:.:.. :  :.:... :..:. .  :::
XP_005 MSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KB9 QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGT
         .: .   .:.   ..  ::.  ....:   :.. : :..      ..: :..   .. 
XP_005 --DLKEKQIESSDYDSSSSKGKKKGRTQKE--KKAARARSK------GKNSDEEAPKTAQ
                 70        80          90             100       110

        110       120         130       140       150       160    
pF1KB9 PKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPI
        : : ..:: .    ..   . . ..  :.:.::::::::::.:::::::::::: .: :
XP_005 KKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSI
              120       130       140       150       160       170

          170       180       190       200       210
pF1KB9 EWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       :::::.::::. ::.:::.::.:  : .:                 
XP_005 EWFHFACVGLTTKPRGKWFCPRCSQERKKK                
              180       190       200                

>>XP_011519267 (OMIM: 608524) PREDICTED: inhibitor of gr  (222 aa)
 initn: 511 init1: 368 opt: 502  Z-score: 422.7  bits: 85.3 E(85289): 8.3e-17
Smith-Waterman score: 502; 38.5% identity (68.7% similar) in 195 aa overlap (1-193:37-221)

                                             10        20        30
pF1KB9                               MLHCVQRALIRSQELGDEKIQIVSQMVELV
                                     .:. .:.:  . .:.::.:.:.. :  :.:
XP_011 RTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMV
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
       ... :..:. .  :::  .: .   .:.   ..  ::.  ....:   :.. : :..   
XP_011 DKHIRRLDTDLARFEA--DLKEKQIESSDYDSSSSKGKKKGRTQKE--KKAARARSK---
         70        80          90       100       110              

              100       110       120         130       140        
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQ
          ..: :..   ..  : : ..:: .    ..   . . ..  :.:.::::::::::.:
XP_011 ---GKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQ
        120       130       140       150       160       170      

      150       160       170       180       190       200        
pF1KB9 VSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAY
       ::::::::::: .: ::::::.::::. ::.:::.::.:  : .:               
XP_011 VSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK              
        180       190       200       210       220                

      210
pF1KB9 NR




210 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:03:47 2016 done: Fri Nov  4 20:03:47 2016
 Total Scan time:  6.540 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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