Result of FASTA (omim) for pF1KB6792
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6792, 155 aa
  1>>>pF1KB6792 155 - 155 aa - 155 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0325+/-0.000325; mu= 13.1385+/- 0.020
 mean_var=57.7105+/-12.075, 0's: 0 Z-trim(116.3): 29  B-trim: 1604 in 1/51
 Lambda= 0.168829
 statistics sampled from 27289 (27318) to 27289 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.32), width:  16
 Scan time:  5.460

The best scores are:                                      opt bits E(85289)
NP_036407 (OMIM: 605507,614204) interleukin-36 rec ( 155) 1060 265.8 1.9e-71
NP_775262 (OMIM: 605507,614204) interleukin-36 rec ( 155) 1060 265.8 1.9e-71
XP_011509423 (OMIM: 137215,147679,612628,612852) P ( 143)  414 108.5 4.2e-24
NP_001305843 (OMIM: 137215,147679,612628,612852) i ( 143)  414 108.5 4.2e-24
XP_005263718 (OMIM: 137215,147679,612628,612852) P ( 143)  414 108.5 4.2e-24
NP_776215 (OMIM: 137215,147679,612628,612852) inte ( 143)  414 108.5 4.2e-24
NP_000568 (OMIM: 137215,147679,612628,612852) inte ( 159)  414 108.5 4.6e-24
NP_776214 (OMIM: 137215,147679,612628,612852) inte ( 177)  414 108.5 5.1e-24
NP_776213 (OMIM: 137215,147679,612628,612852) inte ( 180)  414 108.5 5.1e-24
NP_775184 (OMIM: 615296) interleukin-1 family memb ( 152)  365 96.5 1.7e-20
NP_115945 (OMIM: 615296) interleukin-1 family memb ( 152)  365 96.5 1.7e-20
NP_775270 (OMIM: 605508) interleukin-36 beta isofo ( 157)  260 71.0 8.9e-13
XP_011509264 (OMIM: 605508) PREDICTED: interleukin ( 157)  260 71.0 8.9e-13
XP_016859295 (OMIM: 605509) PREDICTED: interleukin ( 158)  245 67.3 1.1e-11
XP_011509267 (OMIM: 605509) PREDICTED: interleukin ( 158)  245 67.3 1.1e-11
XP_005263696 (OMIM: 605509) PREDICTED: interleukin ( 158)  245 67.3 1.1e-11
NP_055255 (OMIM: 605509) interleukin-36 alpha [Hom ( 158)  245 67.3 1.1e-11
NP_001265497 (OMIM: 605542) interleukin-36 gamma i ( 134)  230 63.6 1.2e-10
NP_062564 (OMIM: 605542) interleukin-36 gamma isof ( 169)  230 63.7 1.5e-10
NP_775297 (OMIM: 605510) interleukin-37 isoform 5  ( 192)  229 63.5   2e-10
NP_775294 (OMIM: 605510) interleukin-37 isoform 2  ( 197)  229 63.5   2e-10
XP_011509265 (OMIM: 605510) PREDICTED: interleukin ( 218)  229 63.5 2.2e-10
NP_055254 (OMIM: 605510) interleukin-37 isoform 1  ( 218)  229 63.5 2.2e-10
NP_775295 (OMIM: 605510) interleukin-37 isoform 3  ( 157)  213 59.5 2.5e-09
XP_011509266 (OMIM: 605510) PREDICTED: interleukin ( 178)  213 59.6 2.8e-09
NP_775296 (OMIM: 605510) interleukin-37 isoform 4  ( 178)  213 59.6 2.8e-09
XP_016859477 (OMIM: 137215,147720) PREDICTED: inte ( 238)  157 46.0 4.5e-05
NP_000567 (OMIM: 137215,147720) interleukin-1 beta ( 269)  157 46.0   5e-05


>>NP_036407 (OMIM: 605507,614204) interleukin-36 recepto  (155 aa)
 initn: 1060 init1: 1060 opt: 1060  Z-score: 1403.5  bits: 265.8 E(85289): 1.9e-71
Smith-Waterman score: 1060; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155)

               10        20        30        40        50        60
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
               70        80        90       100       110       120

              130       140       150     
pF1KB6 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       :::::::::::::::::::::::::::::::::::
NP_036 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
              130       140       150     

>>NP_775262 (OMIM: 605507,614204) interleukin-36 recepto  (155 aa)
 initn: 1060 init1: 1060 opt: 1060  Z-score: 1403.5  bits: 265.8 E(85289): 1.9e-71
Smith-Waterman score: 1060; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155)

               10        20        30        40        50        60
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
               70        80        90       100       110       120

              130       140       150     
pF1KB6 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       :::::::::::::::::::::::::::::::::::
NP_775 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
              130       140       150     

>>XP_011509423 (OMIM: 137215,147679,612628,612852) PREDI  (143 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 553.7  bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)

               10        20        30        40        50          
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
               ::. :   :..::.::::.:: :.. .:   :.:.:::       . :  ..
XP_011      MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
                    10        20        30        40               

       60        70         80        90       100       110       
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
       ::..::..::::   :.:  : :: ::: .:  . :..: :.: : : : :.:::::: :
XP_011 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
       50        60        70        80        90       100        

       120       130       140       150     
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       ::::::. :::::: ::..:..:   . .: ::::.  
XP_011 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
      110       120       130          140   

>>NP_001305843 (OMIM: 137215,147679,612628,612852) inter  (143 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 553.7  bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)

               10        20        30        40        50          
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
               ::. :   :..::.::::.:: :.. .:   :.:.:::       . :  ..
NP_001      MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
                    10        20        30        40               

       60        70         80        90       100       110       
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
       ::..::..::::   :.:  : :: ::: .:  . :..: :.: : : : :.:::::: :
NP_001 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
       50        60        70        80        90       100        

       120       130       140       150     
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       ::::::. :::::: ::..:..:   . .: ::::.  
NP_001 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
      110       120       130          140   

>>XP_005263718 (OMIM: 137215,147679,612628,612852) PREDI  (143 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 553.7  bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)

               10        20        30        40        50          
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
               ::. :   :..::.::::.:: :.. .:   :.:.:::       . :  ..
XP_005      MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
                    10        20        30        40               

       60        70         80        90       100       110       
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
       ::..::..::::   :.:  : :: ::: .:  . :..: :.: : : : :.:::::: :
XP_005 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
       50        60        70        80        90       100        

       120       130       140       150     
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       ::::::. :::::: ::..:..:   . .: ::::.  
XP_005 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
      110       120       130          140   

>>NP_776215 (OMIM: 137215,147679,612628,612852) interleu  (143 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 553.7  bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)

               10        20        30        40        50          
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
               ::. :   :..::.::::.:: :.. .:   :.:.:::       . :  ..
NP_776      MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
                    10        20        30        40               

       60        70         80        90       100       110       
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
       ::..::..::::   :.:  : :: ::: .:  . :..: :.: : : : :.:::::: :
NP_776 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
       50        60        70        80        90       100        

       120       130       140       150     
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       ::::::. :::::: ::..:..:   . .: ::::.  
NP_776 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
      110       120       130          140   

>>NP_000568 (OMIM: 137215,147679,612628,612852) interleu  (159 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 553.0  bits: 108.5 E(85289): 4.6e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:20-157)

                          10        20        30        40         
pF1KB6            MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRW
                          ::. :   :..::.::::.:: :.. .:   :.:.:::   
NP_000 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP---
               10        20        30        40        50          

      50          60        70         80        90       100      
pF1KB6 LDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMG
           . :  ..::..::..::::   :.:  : :: ::: .:  . :..: :.: : : :
NP_000 ----IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG
            60        70        80        90       100       110   

        110       120       130       140       150     
pF1KB6 LTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
        :.:::::: :::::::. :::::: ::..:..:   . .: ::::.  
NP_000 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
           120       130       140          150         

>>NP_776214 (OMIM: 137215,147679,612628,612852) interleu  (177 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 552.3  bits: 108.5 E(85289): 5.1e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:38-175)

                                     10        20        30        
pF1KB6                       MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIK
                                     ::. :   :..::.::::.:: :.. .:  
NP_776 RSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNL
        10        20        30        40        50        60       

       40        50          60        70         80        90     
pF1KB6 GEEISVVPNRWLDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKES
        :.:.:::       . :  ..::..::..::::   :.:  : :: ::: .:  . :..
NP_776 EEKIDVVP-------IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
        70               80        90       100       110       120

         100       110       120       130       140       150     
pF1KB6 KSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       : :.: : : : :.:::::: :::::::. :::::: ::..:..:   . .: ::::.  
NP_776 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
              130       140       150       160          170       

>>NP_776213 (OMIM: 137215,147679,612628,612852) interleu  (180 aa)
 initn: 410 init1: 242 opt: 414  Z-score: 552.2  bits: 108.5 E(85289): 5.1e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:41-178)

                                     10        20        30        
pF1KB6                       MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIK
                                     ::. :   :..::.::::.:: :.. .:  
NP_776 GGGGGEGEDNADSKETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNL
               20        30        40        50        60        70

       40        50          60        70         80        90     
pF1KB6 GEEISVVPNRWLDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKES
        :.:.:::       . :  ..::..::..::::   :.:  : :: ::: .:  . :..
NP_776 EEKIDVVP-------IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
                      80        90       100       110       120   

         100       110       120       130       140       150     
pF1KB6 KSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       : :.: : : : :.:::::: :::::::. :::::: ::..:..:   . .: ::::.  
NP_776 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
           130       140       150       160          170       180

>>NP_775184 (OMIM: 615296) interleukin-1 family member 1  (152 aa)
 initn: 342 init1: 210 opt: 365  Z-score: 488.8  bits: 96.5 E(85289): 1.7e-20
Smith-Waterman score: 365; 43.8% identity (68.8% similar) in 144 aa overlap (11-153:12-150)

                10        20        30        40        50         
pF1KB6  MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVIL
                  .: .  :.:: ...:::.:   : .   .:.: ..::: :  .  :..:
NP_775 MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCC-AEKICILPNRGLARTKVPIFL
               10        20        30         40        50         

      60        70         80        90       100       110        
pF1KB6 GVQGGSQCLSCGVGQE-PTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPG
       :.::::.::.:   .: :.: :: ::: ::: :..:.  :::.. . : .  .:.::.::
NP_775 GIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPG
      60        70        80        90       100       110         

      120       130       140       150     
pF1KB6 WFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
       ::::   : .:::.::.  : ..     : :::.:  
NP_775 WFLCGPAEPQQPVQLTKESEPSAR----TKFYFEQSW
     120       130       140           150  




155 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:18:11 2016 done: Sat Nov  5 18:18:12 2016
 Total Scan time:  5.460 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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