Result of FASTA (omim) for pF1KE0181
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0181, 269 aa
  1>>>pF1KE0181 269 - 269 aa - 269 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.3647+/-0.000431; mu= 19.8259+/- 0.026
 mean_var=59.2721+/-12.378, 0's: 0 Z-trim(108.8): 25  B-trim: 942 in 1/50
 Lambda= 0.166590
 statistics sampled from 16938 (16953) to 16938 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.199), width:  16
 Scan time:  6.320

The best scores are:                                      opt bits E(85289)
NP_149351 (OMIM: 185660) surfeit locus protein 4 i ( 269) 1787 438.2 7.8e-123
XP_011517246 (OMIM: 185660) PREDICTED: surfeit loc ( 260) 1685 413.6 1.8e-115
XP_011517245 (OMIM: 185660) PREDICTED: surfeit loc ( 260) 1685 413.6 1.8e-115
NP_001267717 (OMIM: 185660) surfeit locus protein  ( 254) 1678 411.9 5.7e-115
NP_001267720 (OMIM: 185660) surfeit locus protein  ( 226) 1500 369.1  4e-102
NP_001267719 (OMIM: 185660) surfeit locus protein  ( 226) 1500 369.1  4e-102
NP_001267718 (OMIM: 185660) surfeit locus protein  ( 159) 1052 261.3   8e-70
NP_001267722 (OMIM: 185660) surfeit locus protein  ( 152)  985 245.2 5.4e-65
NP_001267721 (OMIM: 185660) surfeit locus protein  ( 128)  816 204.5 8.1e-53
XP_016870551 (OMIM: 185660) PREDICTED: surfeit loc ( 160)  715 180.3 1.9e-45
XP_011517247 (OMIM: 185660) PREDICTED: surfeit loc ( 206)  585 149.2 5.9e-36


>>NP_149351 (OMIM: 185660) surfeit locus protein 4 isofo  (269 aa)
 initn: 1787 init1: 1787 opt: 1787  Z-score: 2326.3  bits: 438.2 E(85289): 7.8e-123
Smith-Waterman score: 1787; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269)

               10        20        30        40        50        60
pF1KE0 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
              190       200       210       220       230       240

              250       260         
pF1KE0 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
       :::::::::::::::::::::::::::::
NP_149 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
              250       260         

>>XP_011517246 (OMIM: 185660) PREDICTED: surfeit locus p  (260 aa)
 initn: 1685 init1: 1685 opt: 1685  Z-score: 2194.0  bits: 413.6 E(85289): 1.8e-115
Smith-Waterman score: 1685; 98.8% identity (99.6% similar) in 257 aa overlap (13-269:4-260)

               10        20        30        40        50        60
pF1KE0 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
                   .: .::::::::::::::::::::::::::::::::::::::::::::
XP_011          MRSLATEFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KE0 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KE0 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KE0 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
             180       190       200       210       220       230 

              250       260         
pF1KE0 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
       :::::::::::::::::::::::::::::
XP_011 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
             240       250       260

>>XP_011517245 (OMIM: 185660) PREDICTED: surfeit locus p  (260 aa)
 initn: 1685 init1: 1685 opt: 1685  Z-score: 2194.0  bits: 413.6 E(85289): 1.8e-115
Smith-Waterman score: 1685; 98.8% identity (99.6% similar) in 257 aa overlap (13-269:4-260)

               10        20        30        40        50        60
pF1KE0 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
                   .: .::::::::::::::::::::::::::::::::::::::::::::
XP_011          MRSLATEFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KE0 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KE0 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KE0 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
             180       190       200       210       220       230 

              250       260         
pF1KE0 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
       :::::::::::::::::::::::::::::
XP_011 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
             240       250       260

>>NP_001267717 (OMIM: 185660) surfeit locus protein 4 is  (254 aa)
 initn: 1678 init1: 1678 opt: 1678  Z-score: 2185.0  bits: 411.9 E(85289): 5.7e-115
Smith-Waterman score: 1678; 100.0% identity (100.0% similar) in 253 aa overlap (17-269:2-254)

               10        20        30        40        50        60
pF1KE0 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_001                MFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
                              10        20        30        40     

               70        80        90       100       110       120
pF1KE0 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KE0 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KE0 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF
         170       180       190       200       210       220     

              250       260         
pF1KE0 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
       :::::::::::::::::::::::::::::
NP_001 QTMSVIGGLLLVVALGPGGVSMDEKKKEW
         230       240       250    

>>NP_001267720 (OMIM: 185660) surfeit locus protein 4 is  (226 aa)
 initn: 1500 init1: 1500 opt: 1500  Z-score: 1954.5  bits: 369.1 E(85289): 4e-102
Smith-Waterman score: 1500; 100.0% identity (100.0% similar) in 226 aa overlap (44-269:1-226)

            20        30        40        50        60        70   
pF1KE0 ADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWNCGYLLASSFVFLN
                                     ::::::::::::::::::::::::::::::
NP_001                               MWFQWSEQRDYIDTTWNCGYLLASSFVFLN
                                             10        20        30

            80        90       100       110       120       130   
pF1KE0 LLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAE
               40        50        60        70        80        90

           140       150       160       170       180       190   
pF1KE0 SRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMI
              100       110       120       130       140       150

           200       210       220       230       240       250   
pF1KE0 LVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVV
              160       170       180       190       200       210

           260         
pF1KE0 ALGPGGVSMDEKKKEW
       ::::::::::::::::
NP_001 ALGPGGVSMDEKKKEW
              220      

>>NP_001267719 (OMIM: 185660) surfeit locus protein 4 is  (226 aa)
 initn: 1500 init1: 1500 opt: 1500  Z-score: 1954.5  bits: 369.1 E(85289): 4e-102
Smith-Waterman score: 1500; 100.0% identity (100.0% similar) in 226 aa overlap (44-269:1-226)

            20        30        40        50        60        70   
pF1KE0 ADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWNCGYLLASSFVFLN
                                     ::::::::::::::::::::::::::::::
NP_001                               MWFQWSEQRDYIDTTWNCGYLLASSFVFLN
                                             10        20        30

            80        90       100       110       120       130   
pF1KE0 LLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAE
               40        50        60        70        80        90

           140       150       160       170       180       190   
pF1KE0 SRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMI
              100       110       120       130       140       150

           200       210       220       230       240       250   
pF1KE0 LVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVV
              160       170       180       190       200       210

           260         
pF1KE0 ALGPGGVSMDEKKKEW
       ::::::::::::::::
NP_001 ALGPGGVSMDEKKKEW
              220      

>>NP_001267718 (OMIM: 185660) surfeit locus protein 4 is  (159 aa)
 initn: 1070 init1: 1052 opt: 1052  Z-score: 1374.5  bits: 261.3 E(85289): 8e-70
Smith-Waterman score: 1052; 99.4% identity (100.0% similar) in 157 aa overlap (1-157:1-157)

               10        20        30        40        50        60
pF1KE0 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
       ::::::::::::::::::::::::::::::::::::.                       
NP_001 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYLPG                     
              130       140       150                              

              190       200       210       220       230       240
pF1KE0 SIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFF

>>NP_001267722 (OMIM: 185660) surfeit locus protein 4 is  (152 aa)
 initn: 985 init1: 985 opt: 985  Z-score: 1287.8  bits: 245.2 E(85289): 5.4e-65
Smith-Waterman score: 985; 100.0% identity (100.0% similar) in 152 aa overlap (118-269:1-152)

        90       100       110       120       130       140       
pF1KE0 NFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKSMFAGVPT
                                     ::::::::::::::::::::::::::::::
NP_001                               MRNLALGGGLLLLLAESRSEGKSMFAGVPT
                                             10        20        30

       150       160       170       180       190       200       
pF1KE0 MRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMILVAIGFKTKLAALT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMILVAIGFKTKLAALT
               40        50        60        70        80        90

       210       220       230       240       250       260       
pF1KE0 LVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVVALGPGGVSMDEKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVVALGPGGVSMDEKKK
              100       110       120       130       140       150

         
pF1KE0 EW
       ::
NP_001 EW
         

>>NP_001267721 (OMIM: 185660) surfeit locus protein 4 is  (128 aa)
 initn: 816 init1: 816 opt: 816  Z-score: 1069.2  bits: 204.5 E(85289): 8.1e-53
Smith-Waterman score: 816; 100.0% identity (100.0% similar) in 119 aa overlap (1-119:1-119)

               10        20        30        40        50        60
pF1KE0 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_001 CGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFF
                                                                   
NP_001 SRTSWAQL                                                    
                                                                   

>>XP_016870551 (OMIM: 185660) PREDICTED: surfeit locus p  (160 aa)
 initn: 715 init1: 715 opt: 715  Z-score: 936.8  bits: 180.3 E(85289): 1.9e-45
Smith-Waterman score: 715; 99.1% identity (99.1% similar) in 106 aa overlap (14-119:46-151)

                                10        20        30        40   
pF1KE0                  MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIR
                                     : ::::::::::::::::::::::::::::
XP_016 ASVPHTPRPRTCLAAAWCSPPQPPHPWVSVALQFLRVTKQYLPHVARLCLISTFLEDGIR
          20        30        40        50        60        70     

            50        60        70        80        90       100   
pF1KE0 MWFQWSEQRDYIDTTWNCGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWFQWSEQRDYIDTTWNCGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIAL
          80        90       100       110       120       130     

           110       120       130       140       150       160   
pF1KE0 QTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRV
       ::::::::::::::::                                            
XP_016 QTIAYSILWDLKFLMRLSRTSWAQL                                   
         140       150       160                                   




269 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:24:11 2016 done: Thu Nov  3 22:24:12 2016
 Total Scan time:  6.320 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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