Result of FASTA (omim) for pF1KB0980
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0980, 450 aa
  1>>>pF1KB0980 450 - 450 aa - 450 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.6658+/-0.000359; mu= 2.0653+/- 0.022
 mean_var=182.8825+/-38.682, 0's: 0 Z-trim(120.1): 71  B-trim: 1056 in 1/52
 Lambda= 0.094839
 statistics sampled from 34817 (34923) to 34817 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.409), width:  16
 Scan time: 10.980

The best scores are:                                      opt bits E(85289)
NP_003457 (OMIM: 167415,218700) paired box protein ( 450) 3045 428.9 1.4e-119
XP_011510092 (OMIM: 167415,218700) PREDICTED: pair ( 507) 3033 427.2 4.8e-119
XP_011510093 (OMIM: 167415,218700) PREDICTED: pair ( 500) 2713 383.5 7.1e-106
XP_011510096 (OMIM: 167415,218700) PREDICTED: pair ( 387) 2058 293.8 5.5e-79
NP_039246 (OMIM: 167415,218700) paired box protein ( 398) 2050 292.7 1.2e-78
XP_016860368 (OMIM: 167415,218700) PREDICTED: pair ( 402) 2050 292.7 1.2e-78
XP_011510095 (OMIM: 167415,218700) PREDICTED: pair ( 444) 2046 292.2 1.9e-78
XP_011510094 (OMIM: 167415,218700) PREDICTED: pair ( 455) 2038 291.1 4.2e-78
XP_016860367 (OMIM: 167415,218700) PREDICTED: pair ( 459) 2038 291.1 4.2e-78
NP_039247 (OMIM: 167415,218700) paired box protein ( 321) 1780 255.7 1.3e-67
NP_054698 (OMIM: 167415,218700) paired box protein ( 287) 1777 255.2 1.6e-67
NP_003980 (OMIM: 120330,167409,191830,616002) pair ( 409) 1300 190.1 9.5e-48
XP_016871775 (OMIM: 120330,167409,191830,616002) P ( 440) 1300 190.1   1e-47
NP_000269 (OMIM: 120330,167409,191830,616002) pair ( 394) 1287 188.3 3.2e-47
NP_001291498 (OMIM: 120330,167409,191830,616002) p ( 425) 1287 188.3 3.4e-47
NP_003979 (OMIM: 120330,167409,191830,616002) pair ( 396) 1277 186.9 8.2e-47
XP_016871776 (OMIM: 120330,167409,191830,616002) P ( 427) 1277 186.9 8.8e-47
XP_016871777 (OMIM: 120330,167409,191830,616002) P ( 424) 1267 185.6 2.2e-46
NP_001267476 (OMIM: 167414,615545) paired box prot ( 357) 1151 169.6 1.2e-41
NP_001267481 (OMIM: 167414,615545) paired box prot ( 328) 1141 168.3 2.8e-41
NP_001267477 (OMIM: 167414,615545) paired box prot ( 362) 1141 168.3 3.1e-41
NP_057953 (OMIM: 167414,615545) paired box protein ( 391) 1138 167.9 4.3e-41
XP_005251538 (OMIM: 167414,615545) PREDICTED: pair ( 390) 1120 165.4 2.4e-40
NP_001267478 (OMIM: 167414,615545) paired box prot ( 324) 1108 163.7 6.4e-40
XP_011516198 (OMIM: 167414,615545) PREDICTED: pair ( 410) 1098 162.4   2e-39
XP_016871770 (OMIM: 120330,167409,191830,616002) P ( 496) 1089 161.2 5.5e-39
NP_001267479 (OMIM: 167414,615545) paired box prot ( 295) 1081 160.0 7.6e-39
XP_011516199 (OMIM: 167414,615545) PREDICTED: pair ( 409) 1080 160.0 1.1e-38
NP_003978 (OMIM: 120330,167409,191830,616002) pair ( 417) 1023 152.2 2.5e-36
NP_003981 (OMIM: 120330,167409,191830,616002) pair ( 432) 1023 152.2 2.6e-36
XP_016871774 (OMIM: 120330,167409,191830,616002) P ( 448) 1023 152.2 2.6e-36
XP_016871773 (OMIM: 120330,167409,191830,616002) P ( 463) 1023 152.2 2.7e-36
XP_016871772 (OMIM: 120330,167409,191830,616002) P ( 483)  963 144.0 8.3e-34
XP_016871771 (OMIM: 120330,167409,191830,616002) P ( 483)  963 144.0 8.3e-34
NP_001267482 (OMIM: 167414,615545) paired box prot ( 319)  876 132.0 2.3e-30
NP_001267483 (OMIM: 167414,615545) paired box prot ( 348)  876 132.0 2.4e-30
XP_016871778 (OMIM: 120330,167409,191830,616002) P ( 374)  822 124.6 4.3e-28
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422)  791 120.4   9e-27
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422)  791 120.4   9e-27
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422)  791 120.4   9e-27
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422)  791 120.4   9e-27
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401)  775 118.2 3.9e-26
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483)  680 105.3 3.8e-22
NP_001244025 (OMIM: 167411,615560) paired box prot ( 457)  668 103.6 1.1e-21
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479)  668 103.6 1.2e-21
NP_006185 (OMIM: 167416,604625) paired box protein ( 341)  665 103.1 1.2e-21
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484)  668 103.6 1.2e-21
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505)  668 103.7 1.2e-21
NP_006183 (OMIM: 167411,615560) paired box protein ( 534)  668 103.7 1.3e-21
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403)  642 100.0 1.2e-20


>>NP_003457 (OMIM: 167415,218700) paired box protein Pax  (450 aa)
 initn: 3045 init1: 3045 opt: 3045  Z-score: 2267.9  bits: 428.9 E(85289): 1.4e-119
Smith-Waterman score: 3045; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450)

               10        20        30        40        50        60
pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
              370       380       390       400       410       420

              430       440       450
pF1KB0 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL
       ::::::::::::::::::::::::::::::
NP_003 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL
              430       440       450

>>XP_011510092 (OMIM: 167415,218700) PREDICTED: paired b  (507 aa)
 initn: 2606 init1: 2606 opt: 3033  Z-score: 2258.3  bits: 427.2 E(85289): 4.8e-119
Smith-Waterman score: 3033; 99.8% identity (99.8% similar) in 451 aa overlap (1-450:57-507)

                                             10        20        30
pF1KB0                               MPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
                                     ::::::::::::::::::::::::::::::
XP_011 QPAGQGSGRRGPDLREEAPSPRRAASDSPAMPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
         30        40        50        60        70        80      

               40        50        60         70        80         
pF1KB0 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILG-RYYETGSIRPGVIGGSKPKVATPKVV
       ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGSRYYETGSIRPGVIGGSKPKVATPKVV
         90       100       110       120       130       140      

      90       100       110       120       130       140         
pF1KB0 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
        150       160       170       180       190       200      

     150       160       170       180       190       200         
pF1KB0 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
        210       220       230       240       250       260      

     210       220       230       240       250       260         
pF1KB0 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
        270       280       290       300       310       320      

     270       280       290       300       310       320         
pF1KB0 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
        330       340       350       360       370       380      

     330       340       350       360       370       380         
pF1KB0 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
        390       400       410       420       430       440      

     390       400       410       420       430       440         
pF1KB0 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDH
        450       460       470       480       490       500      

     450
pF1KB0 L
       :
XP_011 L
        

>>XP_011510093 (OMIM: 167415,218700) PREDICTED: paired b  (500 aa)
 initn: 2716 init1: 2259 opt: 2713  Z-score: 2021.8  bits: 383.5 E(85289): 7.1e-106
Smith-Waterman score: 2713; 92.0% identity (94.2% similar) in 448 aa overlap (1-444:57-499)

                                             10        20        30
pF1KB0                               MPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
                                     ::::::::::::::::::::::::::::::
XP_011 QPAGQGSGRRGPDLREEAPSPRRAASDSPAMPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
         30        40        50        60        70        80      

               40        50        60         70        80         
pF1KB0 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILG-RYYETGSIRPGVIGGSKPKVATPKVV
       ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGSRYYETGSIRPGVIGGSKPKVATPKVV
         90       100       110       120       130       140      

      90       100       110       120       130       140         
pF1KB0 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
        150       160       170       180       190       200      

     150       160       170       180       190       200         
pF1KB0 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
        210       220       230       240       250       260      

     210       220       230       240       250       260         
pF1KB0 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
        270       280       290       300       310       320      

     270       280       290       300       310       320         
pF1KB0 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
        330       340       350       360       370       380      

     330       340       350       360       370       380         
pF1KB0 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
        390       400       410       420       430       440      

     390       400       410       420          430       440      
pF1KB0 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSL---LSSPYYYSSTSRPSAPPTTATA
       ::::::::.: .:   : :   .:   :    ..:   ...:     :.::.: :: :  
XP_011 AIAGMVAGKERAGRK-GSTAKRKY---WSKEVNTLAMPMATPPT-PPTARPGASPTPAC 
        450       460           470       480        490       500 

        450
pF1KB0 FDHL

>>XP_011510096 (OMIM: 167415,218700) PREDICTED: paired b  (387 aa)
 initn: 2032 init1: 2032 opt: 2058  Z-score: 1539.1  bits: 293.8 E(85289): 5.5e-79
Smith-Waterman score: 2498; 86.0% identity (86.0% similar) in 450 aa overlap (1-450:1-387)

               10        20        30        40        50        60
pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVA-
              250       260       270       280       290          

              310       320       330       340       350       360
pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              370       380       390       400       410       420
pF1KB0 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --GREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
       300       310       320       330       340       350       

              430       440       450
pF1KB0 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL
       ::::::::::::::::::::::::::::::
XP_011 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL
       360       370       380       

>>NP_039246 (OMIM: 167415,218700) paired box protein Pax  (398 aa)
 initn: 2091 init1: 2040 opt: 2050  Z-score: 1533.0  bits: 292.7 E(85289): 1.2e-78
Smith-Waterman score: 2052; 82.6% identity (86.5% similar) in 385 aa overlap (1-385:1-359)

               10        20        30        40        50        60
pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_039 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL
       :  :: :         :.:.:.:  :              ::  .:  .   :.  ..  
NP_039 P--PFWI--------CSKSAPGSRPSM-------------PFPMLPPCT---GSSRARPS
                        310                    320          330    

              370       380       390       400       410       420
pF1KB0 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
        .:..  ::  :   :  : . ...                                   
NP_039 SQGERWWGPRCPDTHPTSPPADRAAMPPLPSQAWWQEVNTLAMPMATPPTPPTARPGASP
          340       350       360       370       380       390    

>>XP_016860368 (OMIM: 167415,218700) PREDICTED: paired b  (402 aa)
 initn: 2062 init1: 2040 opt: 2050  Z-score: 1532.9  bits: 292.7 E(85289): 1.2e-78
Smith-Waterman score: 2052; 82.6% identity (86.5% similar) in 385 aa overlap (1-385:1-359)

               10        20        30        40        50        60
pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_016 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL
       :  :: :         :.:.:.:  :              ::  .:  .   :.  ..  
XP_016 P--PFWI--------CSKSAPGSRPSM-------------PFPMLPPCT---GSSRARPS
                        310                    320          330    

              370       380       390       400       410       420
pF1KB0 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
        .:..  ::  :   :  : . ...                                   
XP_016 SQGERWWGPRCPDTHPTSPPADRAAMPPLPSQAWWQVRRGPAGRGALQRGSIGARWDTRS
          340       350       360       370       380       390    

>>XP_011510095 (OMIM: 167415,218700) PREDICTED: paired b  (444 aa)
 initn: 1593 init1: 1593 opt: 2046  Z-score: 1529.3  bits: 292.2 E(85289): 1.9e-78
Smith-Waterman score: 2486; 85.8% identity (85.8% similar) in 451 aa overlap (1-450:57-444)

                                             10        20        30
pF1KB0                               MPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
                                     ::::::::::::::::::::::::::::::
XP_011 QPAGQGSGRRGPDLREEAPSPRRAASDSPAMPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
         30        40        50        60        70        80      

               40        50        60         70        80         
pF1KB0 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILG-RYYETGSIRPGVIGGSKPKVATPKVV
       ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGSRYYETGSIRPGVIGGSKPKVATPKVV
         90       100       110       120       130       140      

      90       100       110       120       130       140         
pF1KB0 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
        150       160       170       180       190       200      

     150       160       170       180       190       200         
pF1KB0 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
        210       220       230       240       250       260      

     210       220       230       240       250       260         
pF1KB0 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
        270       280       290       300       310       320      

     270       280       290       300       310       320         
pF1KB0 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
       ::::::::::::::::::::::::::::::                              
XP_011 TLDDGKATLTPSNTPLGRNLSTHQTYPVVA------------------------------
        330       340       350                                    

     330       340       350       360       370       380         
pF1KB0 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
                                        :::::::::::::::::::::::::::
XP_011 ---------------------------------GREMVGPTLPGYPPHIPTSGQGSYASS
                                         360       370       380   

     390       400       410       420       430       440         
pF1KB0 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDH
           390       400       410       420       430       440   

     450
pF1KB0 L
       :
XP_011 L
        

>>XP_011510094 (OMIM: 167415,218700) PREDICTED: paired b  (455 aa)
 initn: 2058 init1: 1601 opt: 2038  Z-score: 1523.2  bits: 291.1 E(85289): 4.2e-78
Smith-Waterman score: 2040; 82.4% identity (86.3% similar) in 386 aa overlap (1-385:57-416)

                                             10        20        30
pF1KB0                               MPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
                                     ::::::::::::::::::::::::::::::
XP_011 QPAGQGSGRRGPDLREEAPSPRRAASDSPAMPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
         30        40        50        60        70        80      

               40        50        60         70        80         
pF1KB0 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILG-RYYETGSIRPGVIGGSKPKVATPKVV
       ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGSRYYETGSIRPGVIGGSKPKVATPKVV
         90       100       110       120       130       140      

      90       100       110       120       130       140         
pF1KB0 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
        150       160       170       180       190       200      

     150       160       170       180       190       200         
pF1KB0 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
        210       220       230       240       250       260      

     210       220       230       240       250       260         
pF1KB0 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
        270       280       290       300       310       320      

     270       280       290       300       310       320         
pF1KB0 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
       :::::::::::::::::::::::::::::: :  :: :         :.:.:.:  :   
XP_011 TLDDGKATLTPSNTPLGRNLSTHQTYPVVAAP--PFWI--------CSKSAPGSRPSM--
        330       340       350         360               370      

     330       340       350       360       370       380         
pF1KB0 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
                  ::  .:  .   :.  ..   .:..  ::  :   :  : . ...    
XP_011 -----------PFPMLPPCT---GSSRARPSSQGERWWGPRCPDTHPTSPPADRAAMPPL
                     380          390       400       410       420

     390       400       410       420       430       440         
pF1KB0 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDH
                                                                   
XP_011 PSQAWWQEVNTLAMPMATPPTPPTARPGASPTPAC                         
              430       440       450                              

>>XP_016860367 (OMIM: 167415,218700) PREDICTED: paired b  (459 aa)
 initn: 1601 init1: 1601 opt: 2038  Z-score: 1523.2  bits: 291.1 E(85289): 4.2e-78
Smith-Waterman score: 2040; 82.4% identity (86.3% similar) in 386 aa overlap (1-385:57-416)

                                             10        20        30
pF1KB0                               MPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
                                     ::::::::::::::::::::::::::::::
XP_016 QPAGQGSGRRGPDLREEAPSPRRAASDSPAMPHNSIRSGHGGLNQLGGAFVNGRPLPEVV
         30        40        50        60        70        80      

               40        50        60         70        80         
pF1KB0 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILG-RYYETGSIRPGVIGGSKPKVATPKVV
       ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 RQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGSRYYETGSIRPGVIGGSKPKVATPKVV
         90       100       110       120       130       140      

      90       100       110       120       130       140         
pF1KB0 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVA
        150       160       170       180       190       200      

     150       160       170       180       190       200         
pF1KB0 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLS
        210       220       230       240       250       260      

     210       220       230       240       250       260         
pF1KB0 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYPLPLLNS
        270       280       290       300       310       320      

     270       280       290       300       310       320         
pF1KB0 TLDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAF
       :::::::::::::::::::::::::::::: :  :: :         :.:.:.:  :   
XP_016 TLDDGKATLTPSNTPLGRNLSTHQTYPVVAAP--PFWI--------CSKSAPGSRPSM--
        330       340       350         360               370      

     330       340       350       360       370       380         
pF1KB0 LDLQQVGSGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASS
                  ::  .:  .   :.  ..   .:..  ::  :   :  : . ...    
XP_016 -----------PFPMLPPCT---GSSRARPSSQGERWWGPRCPDTHPTSPPADRAAMPPL
                     380          390       400       410       420

     390       400       410       420       430       440         
pF1KB0 AIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDH
                                                                   
XP_016 PSQAWWQVRRGPAGRGALQRGSIGARWDTRSKRHTVPYS                     
              430       440       450                              

>>NP_039247 (OMIM: 167415,218700) paired box protein Pax  (321 aa)
 initn: 1829 init1: 1778 opt: 1780  Z-score: 1334.7  bits: 255.7 E(85289): 1.3e-67
Smith-Waterman score: 1780; 85.2% identity (89.6% similar) in 317 aa overlap (1-312:1-317)

               10        20        30        40        50        60
pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

              250       260           270        280       290     
pF1KB0 ERQHYPEAYASPSHTKGEQGLY---P-LPLLNSTLDDG-KATLTPSNTPLGRNLSTHQTY
       ::::::::::::::::::::     :  :  . :   . .:.. :  .    .  .  ..
NP_039 ERQHYPEAYASPSHTKGEQGERWWGPRCPDTHPTSPPADRAAMPPLPSQAWWQEVNTLAM
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB0 PVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQF
       :... :  : :    .:                                           
NP_039 PMATPPTPPTARPGASPTPAC                                       
              310       320                                        




450 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 17:39:55 2016 done: Sat Nov  5 17:39:56 2016
 Total Scan time: 10.980 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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