Result of FASTA (omim) for pF1KB6909
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6909, 205 aa
  1>>>pF1KB6909 205 - 205 aa - 205 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5128+/-0.000254; mu= 14.4741+/- 0.016
 mean_var=86.6344+/-17.511, 0's: 0 Z-trim(121.3): 18  B-trim: 0 in 0/56
 Lambda= 0.137794
 statistics sampled from 37610 (37630) to 37610 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.441), width:  16
 Scan time:  5.960

The best scores are:                                      opt bits E(85289)
NP_001531 (OMIM: 602195,606595,608634) heat shock  ( 205) 1405 288.0 7.4e-78
NP_055180 (OMIM: 158590,608014,608673) heat shock  ( 196)  395 87.2   2e-17
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175)  384 84.9 8.2e-17
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175)  384 84.9 8.2e-17
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175)  384 84.9 8.2e-17
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175)  384 84.9 8.2e-17
NP_000385 (OMIM: 123580,604219) alpha-crystallin A ( 173)  360 80.2 2.2e-15
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108)  345 77.0 1.2e-14
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160)  320 72.2 5.2e-13
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136)  313 70.7 1.2e-12
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182)  309 70.0 2.6e-12
NP_006299 (OMIM: 604624,613376) heat shock protein ( 150)  224 53.1 2.7e-07
XP_011539552 (OMIM: 610692) PREDICTED: heat shock  ( 262)  172 42.9 0.00054
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170)  168 42.0 0.00068
XP_011539551 (OMIM: 610692) PREDICTED: heat shock  ( 263)  169 42.3 0.00082


>>NP_001531 (OMIM: 602195,606595,608634) heat shock prot  (205 aa)
 initn: 1405 init1: 1405 opt: 1405  Z-score: 1518.8  bits: 288.0 E(85289): 7.4e-78
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)

               10        20        30        40        50        60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
              130       140       150       160       170       180

              190       200     
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
       :::::::::::::::::::::::::
NP_001 IPVTFESRAQLGGPEAAKSDETAAK
              190       200     

>>NP_055180 (OMIM: 158590,608014,608673) heat shock prot  (196 aa)
 initn: 441 init1: 303 opt: 395  Z-score: 433.9  bits: 87.2 E(85289): 2e-17
Smith-Waterman score: 405; 39.6% identity (62.0% similar) in 187 aa overlap (1-174:1-176)

               10           20        30        40               50
pF1KB6 MTERRVPFSLLRGPSW---DPFRDWYPHSRLFDQAFGLPRLPEE----WSQWLG---GSS
       :.. ..:::  . ::    :::::    :::.:..::.  .:..    : .:     .:.
NP_055 MADGQMPFSC-HYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSA
               10         20        30        40        50         

                 60        70        80        90       100        
pF1KB6 WPGYVRP--LPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDE
       ::: .:   .: .   .   ..:: .:          .     .. :.: ..:. : :.:
NP_055 WPGTLRSGMVPRGPTATARFGVPAEGR----------TPPPFPGEPWKVCVNVHSFKPEE
      60        70        80                  90       100         

      110       120       130       140       150       160        
pF1KB6 LTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAP
       : :::::: ::..:::::.:.: : .:. ::.:  ::  :::. : .:::::: : .:::
NP_055 LMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAP
     110       120       130       140       150       160         

       170       180       190       200     
pF1KB6 -MPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
        .:  .:                               
NP_055 QVPPYSTFGESSFNNELPQDSQEVTCT           
     170       180       190                 

>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a  (175 aa)
 initn: 420 init1: 349 opt: 384  Z-score: 422.8  bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)

               10        20        30        40        50        60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
                        ::  ..  :::::: ::   :  .     . :  : :.::   
NP_001      MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
                    10        20        30         40        50    

               70        80        90       100       110       120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
                 :.. :: :  ...:.::.:   ::. :.:::.::.:.:: ::.   :.:.
NP_001 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
                         60        70        80        90       100

              130       140       150       160       170       180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
        :::::::::::.::: : ::: .:  :::  ..:::: .:.:::..:  ...  . : :
NP_001 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
              110       120       130       140       150          

              190       200     
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
       ::.: : .                 
NP_001 IPITREEKPAVTAAPKK        
      160       170             

>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184  (175 aa)
 initn: 420 init1: 349 opt: 384  Z-score: 422.8  bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)

               10        20        30        40        50        60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
                        ::  ..  :::::: ::   :  .     . :  : :.::   
NP_001      MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
                    10        20        30         40        50    

               70        80        90       100       110       120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
                 :.. :: :  ...:.::.:   ::. :.:::.::.:.:: ::.   :.:.
NP_001 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
                         60        70        80        90       100

              130       140       150       160       170       180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
        :::::::::::.::: : ::: .:  :::  ..:::: .:.:::..:  ...  . : :
NP_001 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
              110       120       130       140       150          

              190       200     
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
       ::.: : .                 
NP_001 IPITREEKPAVTAAPKK        
      160       170             

>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184  (175 aa)
 initn: 420 init1: 349 opt: 384  Z-score: 422.8  bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)

               10        20        30        40        50        60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
                        ::  ..  :::::: ::   :  .     . :  : :.::   
NP_001      MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
                    10        20        30         40        50    

               70        80        90       100       110       120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
                 :.. :: :  ...:.::.:   ::. :.:::.::.:.:: ::.   :.:.
NP_001 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
                         60        70        80        90       100

              130       140       150       160       170       180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
        :::::::::::.::: : ::: .:  :::  ..:::: .:.:::..:  ...  . : :
NP_001 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
              110       120       130       140       150          

              190       200     
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
       ::.: : .                 
NP_001 IPITREEKPAVTAAPKK        
      160       170             

>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184  (175 aa)
 initn: 420 init1: 349 opt: 384  Z-score: 422.8  bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)

               10        20        30        40        50        60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
                        ::  ..  :::::: ::   :  .     . :  : :.::   
XP_011      MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
                    10        20        30         40        50    

               70        80        90       100       110       120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
                 :.. :: :  ...:.::.:   ::. :.:::.::.:.:: ::.   :.:.
XP_011 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
                         60        70        80        90       100

              130       140       150       160       170       180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
        :::::::::::.::: : ::: .:  :::  ..:::: .:.:::..:  ...  . : :
XP_011 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
              110       120       130       140       150          

              190       200     
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
       ::.: : .                 
XP_011 IPITREEKPAVTAAPKK        
      160       170             

>>NP_000385 (OMIM: 123580,604219) alpha-crystallin A cha  (173 aa)
 initn: 382 init1: 327 opt: 360  Z-score: 397.1  bits: 80.2 E(85289): 2.2e-15
Smith-Waterman score: 364; 41.4% identity (60.9% similar) in 174 aa overlap (18-188:16-166)

               10        20        30        40        50        60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
                        ::   :: :::::: ::   .  .   .:...           
NP_000   MDVTIQHPWFKRTLGPF---YP-SRLFDQFFGEGLFEYDLLPFLSST-----------
                 10            20        30        40              

               70        80         90       100       110         
pF1KB6 AAIESPAVAAPAYSRALSRQ-LSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVE
                .: : ..: :  :.::.::.:   :.. . :::.::.:..::::..:  ::
NP_000 --------ISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVE
                    50        60        70        80        90     

     120       130       140       150       160       170         
pF1KB6 ITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LATQSN
       : :::.::::.:::::: : :.: :: .:: . .: ::: .: ::  .:  .  : .   
NP_000 IHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHA
         100       110       120       130       140       150     

       180       190       200     
pF1KB6 EITIPVTFESRAQLGGPEAAKSDETAAK
       : .:::. : .                 
NP_000 ERAIPVSREEKPTSAPSS          
         160       170             

>>NP_001317308 (OMIM: 123590,608810,613763,613869,615184  (108 aa)
 initn: 341 init1: 321 opt: 345  Z-score: 383.8  bits: 77.0 E(85289): 1.2e-14
Smith-Waterman score: 345; 52.5% identity (75.2% similar) in 101 aa overlap (88-188:1-99)

        60        70        80        90       100       110       
pF1KB6 LPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGV
                                     .:   ::. :.:::.::.:.:: ::.   :
NP_001                               MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
                                             10        20        30

       120       130       140       150       160       170       
pF1KB6 VEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSN
       .:. :::::::::::.::: : ::: .:  :::  ..:::: .:.:::..:  ...  . 
NP_001 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GP
               40        50        60        70        80          

       180       190       200     
pF1KB6 EITIPVTFESRAQLGGPEAAKSDETAAK
       : :::.: : .                 
NP_001 ERTIPITREEKPAVTAAPKK        
       90       100                

>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho  (160 aa)
 initn: 367 init1: 289 opt: 320  Z-score: 354.6  bits: 72.2 E(85289): 5.2e-13
Smith-Waterman score: 330; 38.4% identity (58.5% similar) in 159 aa overlap (14-167:9-146)

               10             20        30        40        50     
pF1KB6 MTERRVPFSLLRGPSW-----DPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYV
                    :::      :.      .::::: ::   :  : .     .  : :.
NP_653      MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYL
                    10        20        30        40        50     

          60        70        80        90       100       110     
pF1KB6 RPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKD
       :        .:.:: :             :...     .. : :::.::.:.:..::.  
NP_653 R--------APSVALP-------------VAQVPTDPGHFSVLLDVKHFSPEEIAVKVVG
                  60                     70        80        90    

         120       130       140       150       160       170     
pF1KB6 GVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQ
         ::. ..:::: ::::...: : :.: :::::::. :.:.:::::.:...:        
NP_653 EHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAP
          100       110       120       130       140       150    

         180       190       200     
pF1KB6 SNEITIPVTFESRAQLGGPEAAKSDETAAK
                                     
NP_653 PPAAAK                        
          160                        

>>XP_005261150 (OMIM: 123580,604219) PREDICTED: alpha-cr  (136 aa)
 initn: 312 init1: 282 opt: 313  Z-score: 348.0  bits: 70.7 E(85289): 1.2e-12
Smith-Waterman score: 313; 48.1% identity (71.2% similar) in 104 aa overlap (87-188:26-129)

         60        70        80        90       100       110      
pF1KB6 PLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDG
                                     ..:   :.. . :::.::.:..::::..: 
XP_005      MPVCPGDSHRPPKALPHLVCGRRGRQVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
                    10        20        30        40        50     

        120       130       140       150       160       170      
pF1KB6 VVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LAT
        ::: :::.::::.:::::: : :.: :: .:: . .: ::: .: ::  .:  .  : .
XP_005 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
          60        70        80        90       100       110     

          180       190       200     
pF1KB6 QSNEITIPVTFESRAQLGGPEAAKSDETAAK
          : .:::. : .                 
XP_005 THAERAIPVSREEKPTSAPSS          
         120       130                




205 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 13:02:14 2016 done: Fri Nov  4 13:02:15 2016
 Total Scan time:  5.960 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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