Result of FASTA (omim) for pF1KB6908
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6908, 224 aa
  1>>>pF1KB6908 224 - 224 aa - 224 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3325+/-0.00034; mu= 14.7952+/- 0.021
 mean_var=74.8421+/-14.895, 0's: 0 Z-trim(115.1): 53  B-trim: 319 in 1/53
 Lambda= 0.148252
 statistics sampled from 25269 (25323) to 25269 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.297), width:  16
 Scan time:  6.360

The best scores are:                                      opt bits E(85289)
NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans ( 224) 1469 323.1 2.4e-88
XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-pr ( 229) 1369 301.7 6.7e-82
XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-pr ( 191) 1232 272.3 3.9e-73
XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-pr ( 196) 1132 250.9 1.1e-66
XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-pr ( 142)  305 74.0 1.5e-13
NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142)  305 74.0 1.5e-13
NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-tr ( 142)  305 74.0 1.5e-13
NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142)  305 74.0 1.5e-13
NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108)  291 70.9 9.5e-13
NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108)  291 70.9 9.5e-13
NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459)  287 70.5 5.4e-12
NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans ( 108)  277 67.9 7.6e-12
NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl ( 268)  266 65.8 7.9e-11
NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457)  266 66.0 1.2e-10
NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457)  266 66.0 1.2e-10
NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457)  266 66.0 1.2e-10
XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414)  263 65.3 1.7e-10
NP_851939 (OMIM: 607062) peptidyl-prolyl cis-trans ( 222)  250 62.3 7.3e-10
NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-tr ( 221)  239 60.0 3.7e-09
NP_060416 (OMIM: 614505,614557) peptidyl-prolyl ci ( 211)  229 57.8 1.6e-08
XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-pr (  79)  214 54.3 6.7e-08
XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-pr (  79)  214 54.3 6.7e-08
NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-tr (  79)  214 54.3 6.7e-08
XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-pr (  79)  214 54.3 6.7e-08
XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-pr (  79)  214 54.3 6.7e-08
NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-tr (  79)  214 54.3 6.7e-08
XP_011523402 (OMIM: 259450,607063,610968) PREDICTE ( 510)  215 55.1 2.5e-07
NP_068758 (OMIM: 259450,607063,610968) peptidyl-pr ( 582)  215 55.1 2.8e-07
XP_011523401 (OMIM: 259450,607063,610968) PREDICTE ( 601)  215 55.1 2.9e-07
NP_001271272 (OMIM: 616257) peptidyl-prolyl cis-tr ( 338)  205 52.8   8e-07
NP_057678 (OMIM: 610571) peptidyl-prolyl cis-trans ( 201)  199 51.4 1.3e-06
XP_011513417 (OMIM: 616257) PREDICTED: peptidyl-pr ( 359)  187 49.0 1.2e-05
NP_009201 (OMIM: 616257) peptidyl-prolyl cis-trans ( 570)  187 49.1 1.8e-05
NP_001271270 (OMIM: 616257) peptidyl-prolyl cis-tr ( 623)  187 49.2 1.9e-05
XP_005246695 (OMIM: 607062) PREDICTED: peptidyl-pr ( 181)  179 47.1 2.3e-05
NP_001137254 (OMIM: 610571) peptidyl-prolyl cis-tr ( 146)  170 45.1 7.4e-05
XP_016868231 (OMIM: 604839) PREDICTED: inactive pe ( 266)  168 44.8 0.00016
XP_006716216 (OMIM: 604839) PREDICTED: inactive pe ( 282)  168 44.9 0.00017
XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317)  168 44.9 0.00018
NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322)  168 44.9 0.00019
NP_003593 (OMIM: 604839) inactive peptidyl-prolyl  ( 327)  168 44.9 0.00019
NP_473374 (OMIM: 600620) peptidyl-prolyl cis-trans (  80)  145 39.6  0.0019
XP_011531001 (OMIM: 600620) PREDICTED: peptidyl-pr ( 100)  145 39.6  0.0022
NP_001268233 (OMIM: 604839) inactive peptidyl-prol ( 297)  147 40.4  0.0039


>>NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans iso  (224 aa)
 initn: 1469 init1: 1469 opt: 1469  Z-score: 1707.1  bits: 323.1 E(85289): 2.4e-88
Smith-Waterman score: 1469; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)

               10        20        30        40        50        60
pF1KB6 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
              130       140       150       160       170       180

              190       200       210       220    
pF1KB6 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
       ::::::::::::::::::::::::::::::::::::::::::::
NP_002 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
              190       200       210       220    

>>XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-prolyl  (229 aa)
 initn: 1396 init1: 1369 opt: 1369  Z-score: 1591.3  bits: 301.7 E(85289): 6.7e-82
Smith-Waterman score: 1369; 99.5% identity (99.5% similar) in 209 aa overlap (1-209:1-209)

               10        20        30        40        50        60
pF1KB6 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
              130       140       150       160       170       180

              190       200       210       220         
pF1KB6 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID     
       ::::::::::::::::::::::::::: :                    
XP_016 TMSKGEKARLEIEPEWAYGKKGQPDAKYPFFPFIIKVEKKKTSRSPLRM
              190       200       210       220         

>>XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-prolyl  (191 aa)
 initn: 1232 init1: 1232 opt: 1232  Z-score: 1434.1  bits: 272.3 E(85289): 3.9e-73
Smith-Waterman score: 1232; 100.0% identity (100.0% similar) in 188 aa overlap (37-224:4-191)

         10        20        30        40        50        60      
pF1KB6 QRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
                                     ::::::::::::::::::::::::::::::
XP_011                            MLKFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
                                          10        20        30   

         70        80        90       100       110       120      
pF1KB6 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
            40        50        60        70        80        90   

        130       140       150       160       170       180      
pF1KB6 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
           100       110       120       130       140       150   

        190       200       210       220    
pF1KB6 KARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
       ::::::::::::::::::::::::::::::::::::::
XP_011 KARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
           160       170       180       190 

>>XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-prolyl  (196 aa)
 initn: 1183 init1: 1132 opt: 1132  Z-score: 1318.3  bits: 250.9 E(85289): 1.1e-66
Smith-Waterman score: 1132; 99.4% identity (99.4% similar) in 173 aa overlap (37-209:4-176)

         10        20        30        40        50        60      
pF1KB6 QRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
                                     ::::::::::::::::::::::::::::::
XP_016                            MLKFLAEHKLLGNIKNVAKTANKDHLVTAYNHL
                                          10        20        30   

         70        80        90       100       110       120      
pF1KB6 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPK
            40        50        60        70        80        90   

        130       140       150       160       170       180      
pF1KB6 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGE
           100       110       120       130       140       150   

        190       200       210       220         
pF1KB6 KARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID     
       ::::::::::::::::::::: :                    
XP_016 KARLEIEPEWAYGKKGQPDAKYPFFPFIIKVEKKKTSRSPLRM
           160       170       180       190      

>>XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-prolyl  (142 aa)
 initn: 264 init1: 128 opt: 305  Z-score: 364.4  bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)

          80        90       100       110       120        130    
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
                                     ::  :   .: :. :.  .  .::::.:  
XP_005      MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
                    10        20        30        40        50     

          140       150       160       170       180       190    
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
       ::: :.::: ::...  .       .:. :..:.:.::.:::..:: : .::: .: :  
XP_005 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
          60        70               80        90       100        

          200       210       220         
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID     
       : .::..: :  ::: .: :.:::::. :.     
XP_005 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
      110        120       130       140  

>>NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans iso  (142 aa)
 initn: 264 init1: 128 opt: 305  Z-score: 364.4  bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)

          80        90       100       110       120        130    
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
                                     ::  :   .: :. :.  .  .::::.:  
NP_476      MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
                    10        20        30        40        50     

          140       150       160       170       180       190    
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
       ::: :.::: ::...  .       .:. :..:.:.::.:::..:: : .::: .: :  
NP_476 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
          60        70               80        90       100        

          200       210       220         
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID     
       : .::..: :  ::: .: :.:::::. :.     
NP_476 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
      110        120       130       140  

>>NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-trans   (142 aa)
 initn: 264 init1: 128 opt: 305  Z-score: 364.4  bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)

          80        90       100       110       120        130    
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
                                     ::  :   .: :. :.  .  .::::.:  
NP_001      MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
                    10        20        30        40        50     

          140       150       160       170       180       190    
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
       ::: :.::: ::...  .       .:. :..:.:.::.:::..:: : .::: .: :  
NP_001 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
          60        70               80        90       100        

          200       210       220         
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID     
       : .::..: :  ::: .: :.:::::. :.     
NP_001 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
      110        120       130       140  

>>NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans iso  (142 aa)
 initn: 264 init1: 128 opt: 305  Z-score: 364.4  bits: 74.0 E(85289): 1.5e-13
Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137)

          80        90       100       110       120        130    
pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW
                                     ::  :   .: :. :.  .  .::::.:  
NP_004      MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH
                    10        20        30        40        50     

          140       150       160       170       180       190    
pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP
       ::: :.::: ::...  .       .:. :..:.:.::.:::..:: : .::: .: :  
NP_004 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS
          60        70               80        90       100        

          200       210       220         
pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID     
       : .::..: :  ::: .: :.:::::. :.     
NP_004 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL
      110        120       130       140  

>>NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans iso  (108 aa)
 initn: 298 init1: 164 opt: 291  Z-score: 349.9  bits: 70.9 E(85289): 9.5e-13
Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (116-224:8-108)

          90       100       110       120         130       140   
pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT
                                     .. ::  .:::.:.  :::  ::: :.:: 
NP_463                        MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK
                                      10        20          30     

           150       160       170       180       190       200   
pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ
        ::..      . .: ::..: .:  .:::::.:..  :: :..:.: : :..:::  :.
NP_463 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH
          40               50        60        70        80        

           210       220    
pF1KB6 PDAKIPPNAKLTFEVELVDID
       :   :::.: :.:.:::. ..
NP_463 PGI-IPPHATLVFDVELLKLE
       90        100        

>>NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans iso  (108 aa)
 initn: 298 init1: 164 opt: 291  Z-score: 349.9  bits: 70.9 E(85289): 9.5e-13
Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (116-224:8-108)

          90       100       110       120         130       140   
pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT
                                     .. ::  .:::.:.  :::  ::: :.:: 
NP_000                        MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK
                                      10        20          30     

           150       160       170       180       190       200   
pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ
        ::..      . .: ::..: .:  .:::::.:..  :: :..:.: : :..:::  :.
NP_000 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH
          40               50        60        70        80        

           210       220    
pF1KB6 PDAKIPPNAKLTFEVELVDID
       :   :::.: :.:.:::. ..
NP_000 PGI-IPPHATLVFDVELLKLE
       90        100        




224 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 13:03:25 2016 done: Fri Nov  4 13:03:26 2016
 Total Scan time:  6.360 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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