Result of FASTA (ccds) for pF1KE4526
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4526, 574 aa
  1>>>pF1KE4526 574 - 574 aa - 574 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.7556+/-0.00101; mu= -3.8435+/- 0.061
 mean_var=348.0146+/-72.243, 0's: 0 Z-trim(115.3): 21  B-trim: 393 in 1/54
 Lambda= 0.068750
 statistics sampled from 15799 (15816) to 15799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.486), width:  16
 Scan time:  3.640

The best scores are:                                      opt bits E(32554)
CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15         ( 574) 4089 419.4 6.1e-117
CCDS4129.1 LOX gene_id:4015|Hs108|chr5             ( 417) 1211 133.8 4.1e-31
CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2         ( 608)  758 89.0 1.8e-17
CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2          ( 753)  758 89.1 2.1e-17
CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10         ( 756)  739 87.2 7.9e-17
CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8          ( 774)  738 87.1 8.6e-17


>>CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15              (574 aa)
 initn: 4089 init1: 4089 opt: 4089  Z-score: 2213.0  bits: 419.4 E(32554): 6.1e-117
Smith-Waterman score: 4089; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574)

               10        20        30        40        50        60
pF1KE4 MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE4 RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE4 CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK
              490       500       510       520       530       540

              550       560       570    
pF1KE4 YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
       ::::::::::::::::::::::::::::::::::
CCDS10 YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
              550       560       570    

>>CCDS4129.1 LOX gene_id:4015|Hs108|chr5                  (417 aa)
 initn: 1343 init1: 1168 opt: 1211  Z-score: 672.1  bits: 133.8 E(32554): 4.1e-31
Smith-Waterman score: 1211; 64.4% identity (80.7% similar) in 270 aa overlap (308-571:149-414)

       280       290       300       310         320       330     
pF1KE4 LYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYAN--PPPEAYGPPRALEPPYLPVR
                                     :  :  .:  :: .. :   . . :: : .
CCDS41 PTARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDG--MVGDDPYNPYK
      120       130       140       150       160         170      

         340       350       360           370       380       390 
pF1KE4 SSDTPPPGGERNGAQQGRLSVGSVYRPNQNG----RGLPDLVPDPNYVQASTYVQRAHLY
        ::  :  .  .  .. :   :. :::. .      :::::: :: :.:::::::.  .:
CCDS41 YSDDNPYYNYYDTYERPR--PGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMY
        180       190         200       210       220       230    

             400       410       420       430       440       450 
pF1KE4 SLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQH
       .:::::::.:::::::  .. ::: :::::::::::::::.::::.:::..:::::::::
CCDS41 NLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQH
          240       250       260       270       280       290    

             460       470       480       490       500       510 
pF1KE4 YHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDT
       ::::::::::::::: : ..:::::::::::::..::.:  .:.:::.::::::::::::
CCDS41 YHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDT
          300       310       320       330       340       350    

             520       530       540       550       560       570 
pF1KE4 YNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKI
       :.:::::::::::::.:::::::: :::.:.: :::.:::::::.:.:::... :..: :
CCDS41 YGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTI
          360       370       380       390       400       410    

          
pF1KE4 VQS
          
CCDS41 SPY
          

>>CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2              (608 aa)
 initn: 777 init1: 507 opt: 758  Z-score: 427.1  bits: 89.0 E(32554): 1.8e-17
Smith-Waterman score: 758; 54.0% identity (73.8% similar) in 202 aa overlap (371-571:385-584)

              350       360       370       380       390       400
pF1KE4 PPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEK
                                     ::.     :: ..:..   :. : :::::.
CCDS74 DQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEEN
          360       370       380       390       400       410    

              410       420       430       440       450       460
pF1KE4 CLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSH
       ::::.: . .   :  : :::: ....: : ::: :.  ::.: :: :: :::::: :.:
CCDS74 CLASSARSANWP-YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTH
          420        430       440       450       460       470   

              470       480       490       500        510         
pF1KE4 YDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQ
       ::.: . .: ::::::::::::::. :.    ::: :..   ::.. ::.: :  :::::
CCDS74 YDIL-TPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
            480       490       500       510       520       530  

     520       530       540       550       560       570         
pF1KE4 WIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS     
       :::::::.::::::.: .::.. : :::::::...:: .: :. . . ::.:        
CCDS74 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
            540       550       560       570       580       590  

CCDS74 NRRFERYPGQTSNQII
            600        

>>CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2               (753 aa)
 initn: 748 init1: 507 opt: 758  Z-score: 425.8  bits: 89.1 E(32554): 2.1e-17
Smith-Waterman score: 758; 54.0% identity (73.8% similar) in 202 aa overlap (371-571:530-729)

              350       360       370       380       390       400
pF1KE4 PPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEK
                                     ::.     :: ..:..   :. : :::::.
CCDS19 DQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEEN
     500       510       520       530       540       550         

              410       420       430       440       450       460
pF1KE4 CLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSH
       ::::.: . .   :  : :::: ....: : ::: :.  ::.: :: :: :::::: :.:
CCDS19 CLASSARSANWP-YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTH
     560       570        580       590       600       610        

              470       480       490       500        510         
pF1KE4 YDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQ
       ::.: . .: ::::::::::::::. :.    ::: :..   ::.. ::.: :  :::::
CCDS19 YDIL-TPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
      620        630       640       650       660       670       

     520       530       540       550       560       570         
pF1KE4 WIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS     
       :::::::.::::::.: .::.. : :::::::...:: .: :. . . ::.:        
CCDS19 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
       680       690       700       710       720       730       

CCDS19 NRRFERYPGQTSNQII
       740       750   

>>CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10              (756 aa)
 initn: 598 init1: 478 opt: 739  Z-score: 415.6  bits: 87.2 E(32554): 7.9e-17
Smith-Waterman score: 739; 46.6% identity (66.5% similar) in 251 aa overlap (322-569:483-731)

             300       310       320       330       340           
pF1KE4 DPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPP--GGERNGA
                                     : ::: :  .  :: : :       .:.: 
CCDS74 NWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGP
            460       470       480       490       500       510  

     350       360       370       380       390       400         
pF1KE4 QQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAP
        .   . :      .   . :::: . . :: ..:..   : .: :: ::.::...:   
CCDS74 VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHM
            520       530       540       550       560       570  

     410       420       430       440       450       460         
pF1KE4 EATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATG
       .   :  : ::::  .. : : .:: :.  : .: ::.::.::::.. :.::::: . .:
CCDS74 DWP-YGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLL-TLNG
             580       590       600       610       620        630

     470       480       490       500        510       520        
pF1KE4 KKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQP
       .::::::::::::::..:  :  .::::..   ::.. ::.:::  ::::::.::::: :
CCDS74 SKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGP
              640       650       660       670       680       690

      530       540       550       560       570                  
pF1KE4 GNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS              
       ::::..: :::.: : ::::.::...:  .: :. :   ::                   
CCDS74 GNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQR
              700       710       720       730       740       750

CCDS74 LRNNLI
             

>>CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8               (774 aa)
 initn: 706 init1: 471 opt: 738  Z-score: 414.9  bits: 87.1 E(32554): 8.6e-17
Smith-Waterman score: 738; 46.5% identity (72.2% similar) in 230 aa overlap (344-571:525-748)

           320       330       340       350       360       370   
pF1KE4 ANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLV
                                     ::  .  :: .. :.    ....   ::::
CCDS34 WHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETA---PDLV
          500       510       520       530       540          550 

           380       390       400        410       420       430  
pF1KE4 PDPNYVQASTYVQRAHLYSLRCAAEEKCL-ASTAYAPEATDYDVRVLLRFPQRVKNQGTA
        . ..:: .::..   .. :.:: ::.:: ::.: .  .: :  : :::: ....:.: .
CCDS34 LNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGY--RRLLRFSSQIHNNGQS
             560       570       580       590         600         

            440       450       460       470       480       490  
pF1KE4 DFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNL
       :: :.  ::.: ::.::.:::::. :.:::::.  .: ::::::::::::::. :.    
CCDS34 DFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNL-NGTKVAEGHKASFCLEDTECEGDIQ
     610       620       630       640        650       660        

            500        510       520       530       540       550 
pF1KE4 KRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNN
       : : :..   ::.. ::.: :  ::::::.::::: ::.:...: .::.. : :::..::
CCDS34 KNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNN
      670       680       690       700       710       720        

             560       570                           
pF1KE4 VVRCNIHYTGRYVSATNCKIVQS                       
       ...:  .: :. .   ::.:                          
CCDS34 IMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ
      730       740       750       760       770    




574 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 09:10:48 2016 done: Sun Nov  6 09:10:49 2016
 Total Scan time:  3.640 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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