Result of FASTA (ccds) for pF1KB7984
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7984, 324 aa
  1>>>pF1KB7984 324 - 324 aa - 324 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9035+/-0.000782; mu= 5.7939+/- 0.048
 mean_var=169.7870+/-35.039, 0's: 0 Z-trim(113.7): 196  B-trim: 11 in 1/52
 Lambda= 0.098429
 statistics sampled from 14097 (14306) to 14097 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.439), width:  16
 Scan time:  2.570

The best scores are:                                      opt bits E(32554)
CCDS3694.1 PITX2 gene_id:5308|Hs108|chr4           ( 324) 2186 321.8 4.6e-88
CCDS3692.1 PITX2 gene_id:5308|Hs108|chr4           ( 317) 1744 259.0 3.5e-69
CCDS3693.1 PITX2 gene_id:5308|Hs108|chr4           ( 271) 1731 257.1 1.1e-68
CCDS4182.1 PITX1 gene_id:5307|Hs108|chr5           ( 314) 1220 184.6 8.8e-47
CCDS7532.1 PITX3 gene_id:5309|Hs108|chr10          ( 302) 1008 154.5 9.8e-38
CCDS14215.1 ARX gene_id:170302|Hs108|chrX          ( 562)  387 66.5 5.6e-11
CCDS9028.1 ALX1 gene_id:8092|Hs108|chr12           ( 326)  382 65.6   6e-11


>>CCDS3694.1 PITX2 gene_id:5308|Hs108|chr4                (324 aa)
 initn: 2186 init1: 2186 opt: 2186  Z-score: 1694.5  bits: 321.8 E(32554): 4.6e-88
Smith-Waterman score: 2186; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324)

               10        20        30        40        50        60
pF1KB7 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS
              250       260       270       280       290       300

              310       320    
pF1KB7 FGYASVQNPASNLSACQYAVDRPV
       ::::::::::::::::::::::::
CCDS36 FGYASVQNPASNLSACQYAVDRPV
              310       320    

>>CCDS3692.1 PITX2 gene_id:5308|Hs108|chr4                (317 aa)
 initn: 1742 init1: 1742 opt: 1744  Z-score: 1355.5  bits: 259.0 E(32554): 3.5e-69
Smith-Waterman score: 1744; 93.9% identity (95.7% similar) in 279 aa overlap (48-324:39-317)

        20        30        40        50        60          70     
pF1KB7 KLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS--DTSSPEAAEKDKSQQ
                                     :: . : :. . .    . : : :::::::
CCDS36 VSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQ
       10        20        30        40        50        60        

          80        90       100       110       120       130     
pF1KB7 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
       70        80        90       100       110       120        

         140       150       160       170       180       190     
pF1KB7 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
      130       140       150       160       170       180        

         200       210       220       230       240       250     
pF1KB7 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
      190       200       210       220       230       240        

         260       270       280       290       300       310     
pF1KB7 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
      250       260       270       280       290       300        

         320    
pF1KB7 CQYAVDRPV
       :::::::::
CCDS36 CQYAVDRPV
      310       

>>CCDS3693.1 PITX2 gene_id:5308|Hs108|chr4                (271 aa)
 initn: 1731 init1: 1731 opt: 1731  Z-score: 1346.4  bits: 257.1 E(32554): 1.1e-68
Smith-Waterman score: 1731; 100.0% identity (100.0% similar) in 256 aa overlap (69-324:16-271)

       40        50        60        70        80        90        
pF1KB7 LAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
                                     ::::::::::::::::::::::::::::::
CCDS36                METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
                              10        20        30        40     

      100       110       120       130       140       150        
pF1KB7 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
          50        60        70        80        90       100     

      160       170       180       190       200       210        
pF1KB7 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
         110       120       130       140       150       160     

      220       230       240       250       260       270        
pF1KB7 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
         170       180       190       200       210       220     

      280       290       300       310       320    
pF1KB7 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
       ::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
         230       240       250       260       270 

>>CCDS4182.1 PITX1 gene_id:5307|Hs108|chr5                (314 aa)
 initn: 1148 init1: 595 opt: 1220  Z-score: 953.4  bits: 184.6 E(32554): 8.8e-47
Smith-Waterman score: 1228; 62.1% identity (78.2% similar) in 330 aa overlap (1-318:1-312)

               10        20        30        40         50         
pF1KB7 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLA-PGQPRSLDSSKHRLEVHTI
       :. .:: . ::.   : .           :. .. :  :: :..::      . :: .. 
CCDS41 MDAFKGGMSLERLPEGLRPPPPP------PHDMGPAFHLARPADPR------EPLE-NSA
               10        20              30        40              

      60        70         80                90       100       110
pF1KB7 SDTSSPEAAEKDKSQQGKN-EDVGA--------EDPSKKKRQRRQRTHFTSQQLQELEAT
       :..:. :  ::... . :. :: ::        .::.:::.:::::::::::::::::::
CCDS41 SESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEAT
        50        60        70        80        90       100       

              120       130       140       150       160       170
pF1KB7 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGL
       :::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::
CCDS41 FQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGL
       110       120       130       140       150       160       

               180       190       200       210       220         
pF1KB7 MQPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSM
       .:::.:.:  ::::::::::.:. : :::::: :::::.  ::::::::: :.:::::.:
CCDS41 VQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTM
       170       180       190       200         210       220     

     230       240       250       260       270        280        
pF1KB7 SSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSL
        ::: :.:: :.:.:.   :::.:::.. :::::.   ::::. :. :: ::::::::::
CCDS41 PSSMGPGAVPGMPNSG---LNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSL
         230       240          250       260       270       280  

      290       300       310       320    
pF1KB7 ASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
       ::::::.::::::::...:.:::.:.::::      
CCDS41 ASLRLKSKQHSSFGYGGLQGPASGLNACQYNS    
            290       300       310        

>>CCDS7532.1 PITX3 gene_id:5309|Hs108|chr10               (302 aa)
 initn: 1012 init1: 712 opt: 1008  Z-score: 790.9  bits: 154.5 E(32554): 9.8e-38
Smith-Waterman score: 1013; 56.9% identity (77.6% similar) in 304 aa overlap (47-324:6-302)

         20        30        40        50        60        70      
pF1KB7 TKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQG
                                     :. .. :  . ..::...:.    ... .:
CCDS75                          MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKG
                                        10        20        30     

             80               90       100       110       120     
pF1KB7 K----NEDVGA-------EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
       .    .: ..:       :: : ::.::::::::::::::::::::::::::::::::::
CCDS75 QEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
          40        50        60        70        80        90     

         130       140       150       160       170       180     
pF1KB7 AVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNN
       :::::::::::::::::::::::::::.:::::::..:.  ..::. ::...::::::.:
CCDS75 AVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGN
         100       110       120       130       140       150     

         190       200        210       220        230       240   
pF1KB7 WAAKGLTSASLSTKSFPF-FNSMNVNPLSSQSMFSPPNSIS-SMSMSSSMVPSAVTGVPG
       :  :.: .  :..:.::: :::.::.::.:: .::::.::. ::  :.. .:..: : ::
CCDS75 WPPKAL-APPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PG
         160        170       180       190       200       210    

           250       260          270               280       290  
pF1KB7 SSLNSLNNLNNLSSPSLN-SAVPTPA--CPYAPP--------TPPYVYRDTCNSSLASLR
       .    :..:.. . :.:  .:: . :  ::::          . :::::: :::::::::
CCDS75 A----LQGLGG-GPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLR
               220        230       240       250       260        

            300         310       320    
pF1KB7 LKAKQHSSFGYASVQNP--ASNLSACQYAVDRPV
       ::::::.::.: .:..:  :.::: :::::.:::
CCDS75 LKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
      270       280       290       300  

>>CCDS14215.1 ARX gene_id:170302|Hs108|chrX               (562 aa)
 initn: 340 init1: 288 opt: 387  Z-score: 310.6  bits: 66.5 E(32554): 5.6e-11
Smith-Waterman score: 387; 35.4% identity (61.0% similar) in 254 aa overlap (65-300:299-544)

           40        50        60        70        80          90  
pF1KB7 MASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGA--EDPSKKKRQ
                                     :: ::   ....   ..:.  :.   :..:
CCDS14 AATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQ
      270       280       290       300       310       320        

            100       110       120       130       140       150  
pF1KB7 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
       :: :: ::: ::.::: .::...:::. ::::.:.  .::::::.:::.::::::::::.
CCDS14 RRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREK
      330       340       350       360       370       380        

            160           170       180       190       200        
pF1KB7 NQQAELCKNGF---GP-QFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKS-FPFFNSM
          :.    :.   :: . .  ..:: :  :   ..    .. :.:. .. . ::   :.
CCDS14 AG-AQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFP---SL
      390        400       410       420       430       440       

       210       220       230             240       250       260 
pF1KB7 NVNPLSSQSMFSPPNSISSMSMSSSMV------PSAVTGVPGSSLNSLNNLNNLSSPSLN
          : .: :.  :: : . ...:. .       :. .. . :  ....  :.. :. .  
CCDS14 PPPP-GSASL--PP-SGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAAL
           450          460       470       480       490       500

             270            280       290       300       310      
pF1KB7 SAVPTPACPYAPPT-----PPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSAC
          ::::   :  .     :  .  :   ::.:.::::::.:..                
CCDS14 LRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKE
              510       520       530       540       550       560

        320    
pF1KB7 QYAVDRPV
               
CCDS14 VC      
               

>>CCDS9028.1 ALX1 gene_id:8092|Hs108|chr12                (326 aa)
 initn: 396 init1: 348 opt: 382  Z-score: 310.0  bits: 65.6 E(32554): 6e-11
Smith-Waterman score: 430; 33.6% identity (60.1% similar) in 301 aa overlap (3-300:49-320)

                                              10        20         
pF1KB7                             MNCMK--GPL-HLEHRAAGTKLSAVSSSSCHH
                                     :..  ::: . ::..   . :  ..:: ..
CCDS90 DFYMGAGGPLEHVMETLDNESFYSKASAGKCVQAFGPLPRAEHHVRLERTSPCQDSSVNY
       20        30        40        50        60        70        

      30        40        50        60        70        80         
pF1KB7 PQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKK
           ....:   :::  : .  .:   .  :   ::  . ..:..  .  :    . :..
CCDS90 ----GITKV--EGQP--LHTELNRAMDNCNSLRMSPVKGMQEKGELDELGDKCDSNVSSS
           80            90       100       110       120       130

      90       100       110       120       130       140         
pF1KB7 KRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRK
       :. ::.:: ::: ::.::: .::...:::. .::..:. :.::::::.:::.::::::::
CCDS90 KK-RRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRK
               140       150       160       170       180         

     150       160       170       180       190       200         
pF1KB7 RERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNV
       :::  : .  :. :.  ..  . :  : ::  . : ::...  .. ...  .:  .:  .
CCDS90 RERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLPRDTSSCM
     190       200       210       220       230       240         

     210       220       230       240       250       260         
pF1KB7 NPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPAC
       .: : .     : . ::..  :.   .  . ::         :::. . :: ... .   
CCDS90 TPYSHS-----PRTDSSYTGFSNH-QNQFSHVP---------LNNFFTDSLLTGATNG--
     250            260        270                280       290    

     270       280       290       300       310       320    
pF1KB7 PYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
        .:  : :   : .  ::.: ::.:::.:..                        
CCDS90 -HAFETKPEFERRS--SSIAVLRMKAKEHTANISWAM                  
             300         310       320                        




324 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:22:25 2016 done: Sat Nov  5 10:22:25 2016
 Total Scan time:  2.570 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com