Result of FASTA (omim) for pF1KB6957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6957, 213 aa
  1>>>pF1KB6957 213 - 213 aa - 213 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7057+/-0.00026; mu= 13.5854+/- 0.016
 mean_var=93.4145+/-18.318, 0's: 0 Z-trim(121.8): 102  B-trim: 27 in 1/58
 Lambda= 0.132699
 statistics sampled from 38875 (38984) to 38875 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.457), width:  16
 Scan time:  6.230

The best scores are:                                      opt bits E(85289)
NP_064455 (OMIM: 146770,613500) immunoglobulin lam ( 213) 1461 288.7 4.9e-78
XP_011528471 (OMIM: 146770,613500) PREDICTED: immu ( 214) 1449 286.4 2.4e-77
NP_690594 (OMIM: 146770,613500) immunoglobulin lam (  84)  479 100.4 9.4e-22
NP_072049 (OMIM: 612735) major histocompatibility  ( 266)  187 44.9 0.00015
NP_002116 (OMIM: 604776) major histocompatibility  ( 266)  182 43.9  0.0003
XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276)  182 43.9  0.0003
XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA  ( 206)  180 43.4 0.00032
NP_002113 (OMIM: 146880,212750) HLA class II histo ( 255)  180 43.5 0.00037
XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266)  179 43.3 0.00044
NP_002110 (OMIM: 142930) HLA class II histocompati ( 250)  178 43.1 0.00048
NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266)  173 42.2 0.00098
NP_064440 (OMIM: 613503) HLA class II histocompati ( 255)  171 41.8  0.0012
NP_291032 (OMIM: 142880) HLA class II histocompati ( 260)  171 41.8  0.0012
NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260)  171 41.8  0.0012
NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260)  171 41.8  0.0012
NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266)  169 41.4  0.0017
NP_002112 (OMIM: 142858) HLA class II histocompati ( 258)  163 40.2  0.0036
NP_061984 (OMIM: 142860) HLA class II histocompati ( 254)  156 38.9   0.009


>>NP_064455 (OMIM: 146770,613500) immunoglobulin lambda-  (213 aa)
 initn: 1461 init1: 1461 opt: 1461  Z-score: 1522.0  bits: 288.7 E(85289): 4.9e-78
Smith-Waterman score: 1461; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213)

               10        20        30        40        50        60
pF1KB6 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 PSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLS
              130       140       150       160       170       180

              190       200       210   
pF1KB6 LTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
       :::::::::::::::::::::::::::::::::
NP_064 LTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
              190       200       210   

>>XP_011528471 (OMIM: 146770,613500) PREDICTED: immunogl  (214 aa)
 initn: 989 init1: 989 opt: 1449  Z-score: 1509.6  bits: 286.4 E(85289): 2.4e-77
Smith-Waterman score: 1449; 99.5% identity (99.5% similar) in 214 aa overlap (1-213:1-214)

               10        20        30        40        50        60
pF1KB6 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
               10        20        30        40        50        60

                70        80        90       100       110         
pF1KB6 SSLRSRWG-RFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLF
       :::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLRSRWGSRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLF
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB6 PPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYL
              130       140       150       160       170       180

     180       190       200       210   
pF1KB6 SLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
       ::::::::::::::::::::::::::::::::::
XP_011 SLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
              190       200       210    

>>NP_690594 (OMIM: 146770,613500) immunoglobulin lambda-  (84 aa)
 initn: 479 init1: 479 opt: 479  Z-score: 511.5  bits: 100.4 E(85289): 9.4e-22
Smith-Waterman score: 479; 100.0% identity (100.0% similar) in 69 aa overlap (1-69:1-69)

               10        20        30        40        50        60
pF1KB6 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFP
       :::::::::                                                   
NP_690 SSLRSRWGRSAQGHPLGHSVPAVL                                    
               70        80                                        

>>NP_072049 (OMIM: 612735) major histocompatibility comp  (266 aa)
 initn: 149 init1:  81 opt: 187  Z-score: 202.6  bits: 44.9 E(85289): 0.00015
Smith-Waterman score: 187; 32.8% identity (56.9% similar) in 116 aa overlap (92-207:106-215)

              70        80        90       100       110       120 
pF1KB6 SLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPP
                                     :   : .: : ..::  : .. :.::..: 
NP_072 YRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV--QRRVHPQVTVYPA
          80        90       100       110       120         130   

             130       140       150       160       170       180 
pF1KB6 SSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSL
       ... :: ..  ::: .. :::: . : :  .:     ::  :   ....  . .  .:  
NP_072 KTQPLQ-HHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLET
            140       150       160       170       180       190  

             190       200       210                               
pF1KB6 TPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS                            
       .:   :: . :.::: : . :   ::                                  
NP_072 VP---RSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIY
               200       210       220       230       240         

>>NP_002116 (OMIM: 604776) major histocompatibility comp  (266 aa)
 initn: 140 init1:  79 opt: 182  Z-score: 197.4  bits: 43.9 E(85289): 0.0003
Smith-Waterman score: 182; 33.0% identity (57.1% similar) in 112 aa overlap (96-207:110-215)

          70        80        90       100       110       120     
pF1KB6 RWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEE
                                     : .: : ..::  : .. :.::..:  .. 
NP_002 TELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV--QRRVEPKVTVYPARTQT
      80        90       100       110       120         130       

         130       140       150       160       170       180     
pF1KB6 LQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQ
       :: ..  ::: .: :::: . : :  ..     ::  :   ....  . .  .:  .:  
NP_002 LQ-HHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVP--
        140       150       160       170       180       190      

         190       200       210                                   
pF1KB6 WRSRRSYSCQVMHEGSTVEKTVAPAECS                                
        :: . :.::: : . :   ::                                      
NP_002 -RSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQ
           200       210       220       230       240       250   

>>XP_011512864 (OMIM: 604776) PREDICTED: major histocomp  (276 aa)
 initn: 140 init1:  79 opt: 182  Z-score: 197.2  bits: 43.9 E(85289): 0.0003
Smith-Waterman score: 182; 33.0% identity (57.1% similar) in 112 aa overlap (96-207:110-215)

          70        80        90       100       110       120     
pF1KB6 RWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEE
                                     : .: : ..::  : .. :.::..:  .. 
XP_011 TELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV--QRRVEPKVTVYPARTQT
      80        90       100       110       120         130       

         130       140       150       160       170       180     
pF1KB6 LQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQ
       :: ..  ::: .: :::: . : :  ..     ::  :   ....  . .  .:  .:  
XP_011 LQ-HHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVP--
        140       150       160       170       180       190      

         190       200       210                                   
pF1KB6 WRSRRSYSCQVMHEGSTVEKTVAPAECS                                
        :: . :.::: : . :   ::                                      
XP_011 -RSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQ
           200       210       220       230       240       250   

>>XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA clas  (206 aa)
 initn: 176 init1: 142 opt: 180  Z-score: 196.8  bits: 43.4 E(85289): 0.00032
Smith-Waterman score: 180; 34.1% identity (65.9% similar) in 88 aa overlap (114-200:113-195)

            90       100       110       120        130       140  
pF1KB6 PRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEEL-QANKATLVCLMNDFYP
                                     : ::.:  :   : : :  ::.::.....:
XP_006 QGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVTLGQPN--TLICLVDNIFP
             90       100       110       120         130       140

            150       160       170       180       190       200  
pF1KB6 GILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST
        ....:: ..:  .:.::  :.  ..:....   :::.. :    . . :.:.: : :  
XP_006 PVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLP---SADEIYDCKVEHWGLD
              150       160       170       180          190       

            210   
pF1KB6 VEKTVAPAECS
                  
XP_006 QPLLKHWVE  
       200        

>>NP_002113 (OMIM: 146880,212750) HLA class II histocomp  (255 aa)
 initn: 176 init1: 142 opt: 180  Z-score: 195.6  bits: 43.5 E(85289): 0.00037
Smith-Waterman score: 180; 34.1% identity (65.9% similar) in 88 aa overlap (114-200:113-195)

            90       100       110       120        130       140  
pF1KB6 PRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEEL-QANKATLVCLMNDFYP
                                     : ::.:  :   : : :  ::.::.....:
NP_002 QGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVTLGQPN--TLICLVDNIFP
             90       100       110       120         130       140

            150       160       170       180       190       200  
pF1KB6 GILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST
        ....:: ..:  .:.::  :.  ..:....   :::.. :    . . :.:.: : :  
NP_002 PVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLP---SADEIYDCKVEHWGLD
              150       160       170       180          190       

            210                                                  
pF1KB6 VEKTVAPAECS                                               
                                                                 
NP_002 QPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFIIQGLRSVGASRHQGPL
       200       210       220       230       240       250     

>>XP_011546040 (OMIM: 126200,142857,180300,181000) PREDI  (266 aa)
 initn: 138 init1:  81 opt: 179  Z-score: 194.3  bits: 43.3 E(85289): 0.00044
Smith-Waterman score: 179; 29.8% identity (58.1% similar) in 124 aa overlap (76-198:89-206)

          50        60        70        80        90        100    
pF1KB6 QSRALGPGAPGGSSRSSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVT-HVFGSGTQL
                                     ::.. .   .  ... ..:  : .: : ..
XP_011 LFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESF
       60        70        80        90       100       110        

          110       120       130       140       150       160    
pF1KB6 TVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTT
       ::  : .. : ::..: ... :: ..  ::: .. :::: . : :  .:     ::  : 
XP_011 TV--QRRVHPEVTVYPAKTQPLQ-HHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTG
      120         130        140       150       160       170     

          170       180       190       200       210              
pF1KB6 PSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS           
         ....  . .  .:  .:   :: . :.::: :                          
XP_011 LIQNGDWTFQTLVMLETVP---RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGV
         180       190          200       210       220       230  

XP_011 GGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
            240       250       260      

>>NP_002110 (OMIM: 142930) HLA class II histocompatibili  (250 aa)
 initn: 113 init1:  73 opt: 178  Z-score: 193.6  bits: 43.1 E(85289): 0.00048
Smith-Waterman score: 178; 33.0% identity (63.6% similar) in 88 aa overlap (114-200:113-195)

            90       100       110       120        130       140  
pF1KB6 PRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEEL-QANKATLVCLMNDFYP
                                     : ::..: :  :: : :   :.:......:
NP_002 QGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELGQPN--ILICIVDNIFP
             90       100       110       120         130       140

            150       160       170       180       190       200  
pF1KB6 GILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST
        ....::  .:  .:.:: .:.  .: .. .    :: ..:    ..  :.::: : :  
NP_002 PVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVP---SAEDVYDCQVEHWGLD
              150       160       170       180          190       

            210                                             
pF1KB6 VEKTVAPAECS                                          
                                                            
NP_002 APLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR
       200       210       220       230       240       250




213 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:22:31 2016 done: Fri Nov  4 11:22:32 2016
 Total Scan time:  6.230 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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