Result of FASTA (omim) for pF1KB5769
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5769, 750 aa
  1>>>pF1KB5769 750 - 750 aa - 750 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.7150+/-0.000348; mu= -0.5515+/- 0.022
 mean_var=218.5081+/-45.009, 0's: 0 Z-trim(122.1): 366  B-trim: 350 in 1/52
 Lambda= 0.086764
 statistics sampled from 39336 (39727) to 39336 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.466), width:  16
 Scan time: 12.190

The best scores are:                                      opt bits E(85289)
NP_001306779 (OMIM: 610576) rho GTPase-activating  ( 821) 5135 655.8  2e-187
NP_001306781 (OMIM: 610576) rho GTPase-activating  ( 566) 3875 498.0 4.3e-140
XP_016875289 (OMIM: 610576) PREDICTED: rho GTPase- ( 566) 3875 498.0 4.3e-140
XP_005269140 (OMIM: 610576) PREDICTED: rho GTPase- ( 566) 3875 498.0 4.3e-140
NP_001073626 (OMIM: 610576) rho GTPase-activating  ( 640) 3056 395.6 3.5e-109
XP_011536961 (OMIM: 610576) PREDICTED: rho GTPase- ( 640) 3056 395.6 3.5e-109
XP_011536958 (OMIM: 610576) PREDICTED: rho GTPase- ( 731) 3056 395.6 3.9e-109
NP_115885 (OMIM: 610576) rho GTPase-activating pro ( 731) 3056 395.6 3.9e-109
XP_005269141 (OMIM: 610576) PREDICTED: rho GTPase- ( 535) 2921 378.6 3.6e-104
XP_005269142 (OMIM: 610576) PREDICTED: rho GTPase- ( 535) 2921 378.6 3.6e-104
XP_011536959 (OMIM: 610576) PREDICTED: rho GTPase- ( 719) 2921 378.7 4.7e-104
NP_001306780 (OMIM: 610576) rho GTPase-activating  ( 420) 2825 366.5 1.2e-100
XP_011536960 (OMIM: 610576) PREDICTED: rho GTPase- ( 700) 2043 268.8 5.5e-71
XP_016875291 (OMIM: 610576) PREDICTED: rho GTPase- ( 516) 1954 257.6 9.7e-68
XP_016875290 (OMIM: 610576) PREDICTED: rho GTPase- ( 547) 1954 257.6   1e-67
NP_001073625 (OMIM: 610576) rho GTPase-activating  ( 547) 1954 257.6   1e-67
XP_016875292 (OMIM: 610576) PREDICTED: rho GTPase- ( 456) 1796 237.8 7.8e-62
XP_016875293 (OMIM: 610576) PREDICTED: rho GTPase- ( 425) 1332 179.7 2.2e-44
XP_011522773 (OMIM: 610591) PREDICTED: rho GTPase- ( 865)  740 105.7 8.3e-22
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581)  732 104.6 1.2e-21
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722)  732 104.7 1.4e-21
XP_016879800 (OMIM: 610591) PREDICTED: rho GTPase- ( 922)  732 104.7 1.8e-21
XP_011522770 (OMIM: 610591) PREDICTED: rho GTPase- ( 922)  732 104.7 1.8e-21
XP_011522771 (OMIM: 610591) PREDICTED: rho GTPase- ( 900)  722 103.5 4.1e-21
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548)  463 70.9 1.5e-11
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667)  463 71.0 1.8e-11
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689)  463 71.0 1.9e-11
XP_006721810 (OMIM: 610591) PREDICTED: rho GTPase- ( 867)  463 71.0 2.3e-11
NP_001269219 (OMIM: 610591) rho GTPase-activating  ( 889)  463 71.0 2.3e-11
XP_006721808 (OMIM: 610591) PREDICTED: rho GTPase- ( 889)  463 71.0 2.3e-11
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397)  445 68.6 5.6e-11
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432)  445 68.6   6e-11
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475)  445 68.7 6.5e-11
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475)  445 68.7 6.5e-11
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475)  445 68.7 6.5e-11
XP_011509784 (OMIM: 610578) PREDICTED: rho GTPase- ( 416)  427 66.4 2.8e-10
XP_011509783 (OMIM: 610578) PREDICTED: rho GTPase- ( 435)  427 66.4 2.9e-10
XP_011509786 (OMIM: 610578) PREDICTED: rho GTPase- ( 342)  418 65.2 5.2e-10
XP_016880032 (OMIM: 600365) PREDICTED: active brea ( 660)  407 64.0 2.3e-09
XP_016880031 (OMIM: 600365) PREDICTED: active brea ( 663)  407 64.0 2.3e-09
XP_011522117 (OMIM: 600365) PREDICTED: active brea ( 832)  407 64.0 2.8e-09
XP_011522116 (OMIM: 600365) PREDICTED: active brea ( 832)  407 64.0 2.8e-09
XP_011522115 (OMIM: 600365) PREDICTED: active brea ( 841)  407 64.0 2.9e-09
XP_011522114 (OMIM: 600365) PREDICTED: active brea ( 865)  407 64.0 2.9e-09
XP_011522112 (OMIM: 600365) PREDICTED: active brea ( 878)  407 64.0   3e-09
XP_011522772 (OMIM: 610591) PREDICTED: rho GTPase- ( 870)  406 63.9 3.2e-09
XP_016880029 (OMIM: 600365) PREDICTED: active brea (1104)  407 64.1 3.6e-09
XP_016880028 (OMIM: 600365) PREDICTED: active brea (1137)  407 64.1 3.7e-09
XP_016872443 (OMIM: 610577) PREDICTED: rho GTPase- ( 742)  390 61.9 1.1e-08
NP_001257627 (OMIM: 610577) rho GTPase-activating  ( 769)  390 61.9 1.2e-08


>>NP_001306779 (OMIM: 610576) rho GTPase-activating prot  (821 aa)
 initn: 5135 init1: 5135 opt: 5135  Z-score: 3486.0  bits: 655.8 E(85289): 2e-187
Smith-Waterman score: 5135; 99.9% identity (100.0% similar) in 750 aa overlap (1-750:72-821)

                                             10        20        30
pF1KB5                               MLSSRWWPSSWGILGLGPRSPPRGSQLCAL
                                     ::::::::::::::::::::::::::::::
NP_001 EEWPDSHHYPGPTPAPESSDGPHKVTVLATMLSSRWWPSSWGILGLGPRSPPRGSQLCAL
              50        60        70        80        90       100 

               40        50        60        70        80        90
pF1KB5 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPS
             110       120       130       140       150       160 

              100       110       120       130       140       150
pF1KB5 QSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSP
             170       180       190       200       210       220 

              160       170       180       190       200       210
pF1KB5 SFLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPAC
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPAC
             230       240       250       260       270       280 

              220       230       240       250       260       270
pF1KB5 PLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVL
             290       300       310       320       330       340 

              280       290       300       310       320       330
pF1KB5 QPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLN
             350       360       370       380       390       400 

              340       350       360       370       380       390
pF1KB5 MTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAAL
             410       420       430       440       450       460 

              400       410       420       430       440       450
pF1KB5 AHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTG
             470       480       490       500       510       520 

              460       470       480       490       500       510
pF1KB5 RDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN
             530       540       550       560       570       580 

              520       530       540       550       560       570
pF1KB5 RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRG
             590       600       610       620       630       640 

              580       590       600       610       620       630
pF1KB5 LDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVV
             650       660       670       680       690       700 

              640       650       660       670       680       690
pF1KB5 TGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLE
             710       720       730       740       750       760 

              700       710       720       730       740       750
pF1KB5 HLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
             770       780       790       800       810       820 

>>NP_001306781 (OMIM: 610576) rho GTPase-activating prot  (566 aa)
 initn: 3875 init1: 3875 opt: 3875  Z-score: 2636.1  bits: 498.0 E(85289): 4.3e-140
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 566 aa overlap (185-750:1-566)

          160       170       180       190       200       210    
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                             10        20        30

          220       230       240       250       260       270    
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
              100       110       120       130       140       150

          340       350       360       370       380       390    
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
              160       170       180       190       200       210

          400       410       420       430       440       450    
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
              220       230       240       250       260       270

          460       470       480       490       500       510    
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
              280       290       300       310       320       330

          520       530       540       550       560       570    
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
              340       350       360       370       380       390

          580       590       600       610       620       630    
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
              400       410       420       430       440       450

          640       650       660       670       680       690    
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
              460       470       480       490       500       510

          700       710       720       730       740       750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
              520       530       540       550       560      

>>XP_016875289 (OMIM: 610576) PREDICTED: rho GTPase-acti  (566 aa)
 initn: 3875 init1: 3875 opt: 3875  Z-score: 2636.1  bits: 498.0 E(85289): 4.3e-140
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 566 aa overlap (185-750:1-566)

          160       170       180       190       200       210    
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                             10        20        30

          220       230       240       250       260       270    
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
              100       110       120       130       140       150

          340       350       360       370       380       390    
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
              160       170       180       190       200       210

          400       410       420       430       440       450    
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
              220       230       240       250       260       270

          460       470       480       490       500       510    
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
              280       290       300       310       320       330

          520       530       540       550       560       570    
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
              340       350       360       370       380       390

          580       590       600       610       620       630    
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
              400       410       420       430       440       450

          640       650       660       670       680       690    
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
              460       470       480       490       500       510

          700       710       720       730       740       750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
              520       530       540       550       560      

>>XP_005269140 (OMIM: 610576) PREDICTED: rho GTPase-acti  (566 aa)
 initn: 3875 init1: 3875 opt: 3875  Z-score: 2636.1  bits: 498.0 E(85289): 4.3e-140
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 566 aa overlap (185-750:1-566)

          160       170       180       190       200       210    
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                     ::::::::::::::::::::::::::::::
XP_005                               MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                             10        20        30

          220       230       240       250       260       270    
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
              100       110       120       130       140       150

          340       350       360       370       380       390    
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
              160       170       180       190       200       210

          400       410       420       430       440       450    
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
              220       230       240       250       260       270

          460       470       480       490       500       510    
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
              280       290       300       310       320       330

          520       530       540       550       560       570    
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
              340       350       360       370       380       390

          580       590       600       610       620       630    
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
              400       410       420       430       440       450

          640       650       660       670       680       690    
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
              460       470       480       490       500       510

          700       710       720       730       740       750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
              520       530       540       550       560      

>>NP_001073626 (OMIM: 610576) rho GTPase-activating prot  (640 aa)
 initn: 3050 init1: 3050 opt: 3056  Z-score: 2081.2  bits: 395.6 E(85289): 3.5e-109
Smith-Waterman score: 4331; 97.0% identity (97.1% similar) in 658 aa overlap (1-658:1-639)

               10        20        30        40        50        60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_001 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
       :::::::::::::::::                   ::::::::::::::::::::::::
NP_001 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
              430                          440       450       460 

              490       500       510       520       530       540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
             470       480       490       500       510       520 

              550       560       570       580       590       600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
             530       540       550       560       570       580 

              610       620       630       640       650       660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
NP_001 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 
             590       600       610       620       630       640 

              670       680       690       700       710       720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP

>>XP_011536961 (OMIM: 610576) PREDICTED: rho GTPase-acti  (640 aa)
 initn: 3050 init1: 3050 opt: 3056  Z-score: 2081.2  bits: 395.6 E(85289): 3.5e-109
Smith-Waterman score: 4331; 97.0% identity (97.1% similar) in 658 aa overlap (1-658:1-639)

               10        20        30        40        50        60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_011 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
       :::::::::::::::::                   ::::::::::::::::::::::::
XP_011 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
              430                          440       450       460 

              490       500       510       520       530       540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
             470       480       490       500       510       520 

              550       560       570       580       590       600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
             530       540       550       560       570       580 

              610       620       630       640       650       660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_011 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 
             590       600       610       620       630       640 

              670       680       690       700       710       720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP

>>XP_011536958 (OMIM: 610576) PREDICTED: rho GTPase-acti  (731 aa)
 initn: 3050 init1: 3050 opt: 3056  Z-score: 2080.4  bits: 395.6 E(85289): 3.9e-109
Smith-Waterman score: 4953; 97.3% identity (97.5% similar) in 750 aa overlap (1-750:1-731)

               10        20        30        40        50        60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_011 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
       :::::::::::::::::                   ::::::::::::::::::::::::
XP_011 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
              430                          440       450       460 

              490       500       510       520       530       540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
             470       480       490       500       510       520 

              550       560       570       580       590       600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
             530       540       550       560       570       580 

              610       620       630       640       650       660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
             590       600       610       620       630       640 

              670       680       690       700       710       720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
             650       660       670       680       690       700 

              730       740       750
pF1KB5 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::
XP_011 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
             710       720       730 

>>NP_115885 (OMIM: 610576) rho GTPase-activating protein  (731 aa)
 initn: 3050 init1: 3050 opt: 3056  Z-score: 2080.4  bits: 395.6 E(85289): 3.9e-109
Smith-Waterman score: 4953; 97.3% identity (97.5% similar) in 750 aa overlap (1-750:1-731)

               10        20        30        40        50        60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_115 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
       :::::::::::::::::                   ::::::::::::::::::::::::
NP_115 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
              430                          440       450       460 

              490       500       510       520       530       540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
             470       480       490       500       510       520 

              550       560       570       580       590       600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
             530       540       550       560       570       580 

              610       620       630       640       650       660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
             590       600       610       620       630       640 

              670       680       690       700       710       720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
             650       660       670       680       690       700 

              730       740       750
pF1KB5 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::
NP_115 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
             710       720       730 

>>XP_005269141 (OMIM: 610576) PREDICTED: rho GTPase-acti  (535 aa)
 initn: 2897 init1: 2897 opt: 2921  Z-score: 1991.1  bits: 378.6 E(85289): 3.6e-104
Smith-Waterman score: 3589; 94.5% identity (94.5% similar) in 566 aa overlap (185-750:1-535)

          160       170       180       190       200       210    
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                     ::::::::::::::::::::::::::::::
XP_005                               MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                             10        20        30

          220       230       240       250       260       270    
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
       ::::::::::::::::                               :::::::::::::
XP_005 KGFRSDTGTPEPLDPQ-------------------------------EVEKSGLLNMTKI
              100                                      110         

          340       350       360       370       380       390    
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
     120       130       140       150       160       170         

          400       410       420       430       440       450    
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
     180       190       200       210       220       230         

          460       470       480       490       500       510    
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
     240       250       260       270       280       290         

          520       530       540       550       560       570    
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
     300       310       320       330       340       350         

          580       590       600       610       620       630    
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
     360       370       380       390       400       410         

          640       650       660       670       680       690    
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
     420       430       440       450       460       470         

          700       710       720       730       740       750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
     480       490       500       510       520       530     

>>XP_005269142 (OMIM: 610576) PREDICTED: rho GTPase-acti  (535 aa)
 initn: 2897 init1: 2897 opt: 2921  Z-score: 1991.1  bits: 378.6 E(85289): 3.6e-104
Smith-Waterman score: 3589; 94.5% identity (94.5% similar) in 566 aa overlap (185-750:1-535)

          160       170       180       190       200       210    
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                     ::::::::::::::::::::::::::::::
XP_005                               MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
                                             10        20        30

          220       230       240       250       260       270    
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
       ::::::::::::::::                               :::::::::::::
XP_005 KGFRSDTGTPEPLDPQ-------------------------------EVEKSGLLNMTKI
              100                                      110         

          340       350       360       370       380       390    
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
     120       130       140       150       160       170         

          400       410       420       430       440       450    
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
     180       190       200       210       220       230         

          460       470       480       490       500       510    
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
     240       250       260       270       280       290         

          520       530       540       550       560       570    
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
     300       310       320       330       340       350         

          580       590       600       610       620       630    
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
     360       370       380       390       400       410         

          640       650       660       670       680       690    
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
     420       430       440       450       460       470         

          700       710       720       730       740       750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
     480       490       500       510       520       530     




750 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:36:43 2016 done: Sat Nov  5 07:36:44 2016
 Total Scan time: 12.190 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com