Result of FASTA (omim) for pF1KB5572
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5572, 381 aa
  1>>>pF1KB5572 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1722+/-0.000454; mu= 8.1923+/- 0.028
 mean_var=165.0528+/-32.321, 0's: 0 Z-trim(116.2): 81  B-trim: 0 in 0/52
 Lambda= 0.099830
 statistics sampled from 27078 (27163) to 27078 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.318), width:  16
 Scan time:  8.460

The best scores are:                                      opt bits E(85289)
NP_001545 (OMIM: 602369) protein CYR61 precursor [ ( 381) 2749 408.2 1.6e-113
NP_001892 (OMIM: 121009) connective tissue growth  ( 349)  662 107.6 4.5e-23
NP_003872 (OMIM: 603399) WNT1-inducible-signaling  ( 250)  581 95.8 1.2e-19
NP_001310299 (OMIM: 603399) WNT1-inducible-signali ( 250)  581 95.8 1.2e-19
NP_002505 (OMIM: 164958) protein NOV homolog precu ( 357)  576 95.2 2.5e-19
NP_543028 (OMIM: 603398) WNT1-inducible-signaling  ( 280)  512 85.9 1.2e-16
NP_003873 (OMIM: 603398) WNT1-inducible-signaling  ( 367)  512 86.0 1.5e-16
XP_011534525 (OMIM: 208230,603400) PREDICTED: WNT1 ( 160)  474 80.2 3.7e-15
XP_011534522 (OMIM: 208230,603400) PREDICTED: WNT1 ( 354)  416 72.2 2.1e-12
NP_003871 (OMIM: 208230,603400) WNT1-inducible-sig ( 354)  416 72.2 2.1e-12
NP_937882 (OMIM: 208230,603400) WNT1-inducible-sig ( 372)  416 72.2 2.2e-12
NP_001191799 (OMIM: 603398) WNT1-inducible-signali ( 122)  311 56.6 3.5e-08
XP_011534524 (OMIM: 208230,603400) PREDICTED: WNT1 ( 158)  293 54.2 2.6e-07
NP_001310298 (OMIM: 603399) WNT1-inducible-signali ( 218)  280 52.4 1.2e-06
XP_016883606 (OMIM: 603399) PREDICTED: WNT1-induci ( 162)  276 51.7 1.4e-06
NP_001191798 (OMIM: 603398) WNT1-inducible-signali ( 155)  254 48.5 1.2e-05
NP_001284488 (OMIM: 608785) serine protease HTRA3  ( 357)  199 40.9  0.0055
XP_011511898 (OMIM: 608785) PREDICTED: serine prot ( 373)  199 41.0  0.0056
NP_444272 (OMIM: 608785) serine protease HTRA3 iso ( 453)  199 41.0  0.0065


>>NP_001545 (OMIM: 602369) protein CYR61 precursor [Homo  (381 aa)
 initn: 2749 init1: 2749 opt: 2749  Z-score: 2159.1  bits: 408.2 E(85289): 1.6e-113
Smith-Waterman score: 2749; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)

               10        20        30        40        50        60
pF1KB5 MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
              310       320       330       340       350       360

              370       380 
pF1KB5 HANEAAFPFYRLFNDIHKFRD
       :::::::::::::::::::::
NP_001 HANEAAFPFYRLFNDIHKFRD
              370       380 

>>NP_001892 (OMIM: 121009) connective tissue growth fact  (349 aa)
 initn: 1198 init1: 611 opt: 662  Z-score: 535.1  bits: 107.6 E(85289): 4.5e-23
Smith-Waterman score: 1258; 47.6% identity (69.9% similar) in 372 aa overlap (9-376:11-348)

                 10        20         30         40        50      
pF1KB5   MSSRIARALALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVC
                 .:.:: :   .: :.. .: . :.:: : ::.:  ::.:: ::::::.::
NP_001 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB5 AKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPN
       ::::.: :.. .:::  ::: :.::. ..   :.: :. .: :: ... .:..::::: .
NP_001 AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSS
               70        80        90        100       110         

        120       130       140       150       160       170      
pF1KB5 CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQD
       ::.::::.::::::.::: ... ::.  :: :: ::. :.:::::::::     : .:: 
NP_001 CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDE-----P-KDQT
     120       130       140       150       160             170   

        180       190       200       210       220       230      
pF1KB5 GLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSW
        ..:  :.  : ..: :                   :: .: ..       .:.:::: :
NP_001 -VVGPALA--AYRLEDT-------------------FGPDPTMIR-----ANCLVQTTEW
            180                            190            200      

        240       250       260       270       280       290      
pF1KB5 SQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPV
       : :::::: ::::::::::  ::: :..:.: ::::   .  ..:::::: .: :  .:.
NP_001 SACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPI
        210       220       230       240       250       260      

        300       310       320       330       340       350      
pF1KB5 RFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCN
       .:  .:: :.: :: :.:: :.:::::::. : :. ..:.: :::...::.:.:..: :.
NP_001 KFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACH
        270       280       290       300       310       320      

        360       370         380 
pF1KB5 YNCPHANEAAFPFY--RLFNDIHKFRD
       ::::  :.    .:  ....:.     
NP_001 YNCPGDNDIFESLYYRKMYGDMA    
        330       340             

>>NP_003872 (OMIM: 603399) WNT1-inducible-signaling path  (250 aa)
 initn: 783 init1: 573 opt: 581  Z-score: 474.0  bits: 95.8 E(85289): 1.2e-19
Smith-Waterman score: 696; 38.8% identity (60.1% similar) in 263 aa overlap (11-272:10-237)

               10         20        30        40        50         
pF1KB5 MSSRIARALALVVTLLHL-TRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQ
                 :. .:: : ...  . ::. : ::   :.:  :: :: ::::::.:::..
NP_003  MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARR
                10        20        30        40        50         

      60        70        80        90       100       110         
pF1KB5 LNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKH
       :.: :.. . :: ..:: :. ::.  .  ..:    .   :: :.:.:..::.:::.:. 
NP_003 LGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSI
      60        70        80        90       100       110         

     120       130       140       150       160       170         
pF1KB5 QCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLL
       .: : ::.  :.::: ... ::.  ::.:: :.: :.:: ::::           : : :
NP_003 RCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVC----------GQGGGL
     120       130       140       150       160                   

     180       190       200       210       220       230         
pF1KB5 GKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQC
       : .               : :  .: ... : : .. :        :  :   .:.:. :
NP_003 GTQ--------------PLPA--QGPQFSGL-VSSLPP--------GVPCPEWSTAWGPC
     170                       180        190               200    

     240       250       260       270       280       290         
pF1KB5 SKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFT
       : ::: :..:::.:.:  :::  . :.:  :::                           
NP_003 STTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRSPQNSAF              
          210       220       230       240       250              

     300       310       320       330       340       350         
pF1KB5 YAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC

>>NP_001310299 (OMIM: 603399) WNT1-inducible-signaling p  (250 aa)
 initn: 783 init1: 573 opt: 581  Z-score: 474.0  bits: 95.8 E(85289): 1.2e-19
Smith-Waterman score: 696; 38.8% identity (60.1% similar) in 263 aa overlap (11-272:10-237)

               10         20        30        40        50         
pF1KB5 MSSRIARALALVVTLLHL-TRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQ
                 :. .:: : ...  . ::. : ::   :.:  :: :: ::::::.:::..
NP_001  MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARR
                10        20        30        40        50         

      60        70        80        90       100       110         
pF1KB5 LNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKH
       :.: :.. . :: ..:: :. ::.  .  ..:    .   :: :.:.:..::.:::.:. 
NP_001 LGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSI
      60        70        80        90       100       110         

     120       130       140       150       160       170         
pF1KB5 QCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLL
       .: : ::.  :.::: ... ::.  ::.:: :.: :.:: ::::           : : :
NP_001 RCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVC----------GQGGGL
     120       130       140       150       160                   

     180       190       200       210       220       230         
pF1KB5 GKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQC
       : .               : :  .: ... : : .. :        :  :   .:.:. :
NP_001 GTQ--------------PLPA--QGPQFSGL-VSSLPP--------GVPCPEWSTAWGPC
     170                       180        190               200    

     240       250       260       270       280       290         
pF1KB5 SKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFT
       : ::: :..:::.:.:  :::  . :.:  :::                           
NP_001 STTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRSPQNSAF              
          210       220       230       240       250              

     300       310       320       330       340       350         
pF1KB5 YAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC

>>NP_002505 (OMIM: 164958) protein NOV homolog precursor  (357 aa)
 initn: 1148 init1: 345 opt: 576  Z-score: 468.1  bits: 95.2 E(85289): 2.5e-19
Smith-Waterman score: 1112; 44.2% identity (65.5% similar) in 362 aa overlap (9-365:16-343)

                      10        20          30          40         
pF1KB5        MSSRIARALALVVTLLHLTRLALST--CPAAC--HCPLEAPKCAPGVGLVRDG
                      : :.  ::::   . .:  ::  :  .::   : :::::  : ::
NP_002 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDG
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KB5 CGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN
       :.:: :::.: .:.::  .:::...:: :. .:. .   ::: :  ::  : ... ::..
NP_002 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTA-VEGDNCVFDGVIYRS
               70        80        90       100        110         

     110       120       130       140       150       160         
pF1KB5 GESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIK
       ::.:::.:: :::: :: .::.: :  .. ::. .:: :: :.: :.:::.:.:  :   
NP_002 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPD---
     120       130       140       150       160       170         

     170       180       190       200       210       220         
pF1KB5 DPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKC
           ..:.: :  : . : . : : . :.    . ::..                    :
NP_002 ----EEDSLGG--LTLAAYRPEATLGVEV----SDSSVN--------------------C
            180         190           200                          

     230       240       250       260       270        280        
pF1KB5 IVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQ-PVYSSLKKGKKCSK
       : ::: :. :::.:: :.:::::: : .:...:.::.: :::: : :   . :::::: .
NP_002 IEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLR
        210       220       230       240       250       260      

      290       300       310       320       330       340        
pF1KB5 TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVM
       :::: . ... . .: :.. :.:..:: : :::::::. :.:.. .:.:  :.  .: ::
NP_002 TKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVM
        270       280       290       300       310       320      

      350       360       370       380 
pF1KB5 MIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD
       .: .: :. :::. :::                
NP_002 VIGTCTCHTNCPKNNEAFLQELELKTTRGKM  
        330       340       350         

>>NP_543028 (OMIM: 603398) WNT1-inducible-signaling path  (280 aa)
 initn: 734 init1: 507 opt: 512  Z-score: 419.6  bits: 85.9 E(85289): 1.2e-16
Smith-Waterman score: 529; 28.7% identity (45.5% similar) in 356 aa overlap (26-381:49-274)

                    10        20        30        40        50     
pF1KB5      MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKV
                                     :   :.::   :.:  ::.:. ::: :::.
NP_543 TVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKM
       20        30        40        50        60        70        

          60        70        80        90       100       110     
pF1KB5 CAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQP
       ::.::...:...  ::  .:: :..              :  ::     : :  :     
NP_543 CAQQLGDNCTEAAICDPHRGLYCDY--------------SGDRP-----R-YAIGV----
       80        90       100                           110        

         120       130       140       150       160       170     
pF1KB5 NCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQ
        : :       ::: .                           : :              
NP_543 -CAH-------AVGEV---------------------------EAW--------------
                  120                                              

         180       190       200       210       220       230     
pF1KB5 DGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTS
                         ::                                 ::. :. 
NP_543 -----------------HRN---------------------------------CIAYTSP
                                                           130     

         240       250       260       270       280       290     
pF1KB5 WSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEP
       :: :: .:: :.:::..: : .:   .:.:.:..:::   ... .: ::::  . .    
NP_543 WSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEAS
         140       150       160       170       180       190     

         300       310       320       330       340       350     
pF1KB5 VRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC
       . :: :::.:...:.::::: :.:.::: :  ..:. . :.: ::  ::..:. :..: :
NP_543 MNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFC
         200       210       220       230       240       250     

         360       370       380       
pF1KB5 NYNCPHANEAAFPFYRLFNDIHKFRD      
       : .: . :.       .: :.... :      
NP_543 NLSCRNPND-------IFADLESYPDFSEIAN
         260              270       280

>>NP_003873 (OMIM: 603398) WNT1-inducible-signaling path  (367 aa)
 initn: 1031 init1: 507 opt: 512  Z-score: 418.1  bits: 86.0 E(85289): 1.5e-16
Smith-Waterman score: 1016; 39.8% identity (62.2% similar) in 357 aa overlap (26-381:49-361)

                    10        20        30        40        50     
pF1KB5      MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKV
                                     :   :.::   :.:  ::.:. ::: :::.
NP_003 TVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKM
       20        30        40        50        60        70        

          60        70        80         90       100       110    
pF1KB5 CAKQLNEDCSKTQPCDHTKGLECNF-GASSTALKGICRAQSEGRPCEYNSRIYQNGESFQ
       ::.::...:...  ::  .:: :.. :       :.: ::  :  :  ..  :.::.:::
NP_003 CAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC-AQVVGVGCVLDGVRYNNGQSFQ
       80        90       100       110        120       130       

          120       130       140       150       160       170    
pF1KB5 PNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMED
       ::::..:::::::::: :::  ..  : : ::.:: :.. :.:::.::: ::. : : . 
NP_003 PNCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVC-EDDAKRPRKT
       140       150        160       170       180        190     

          180       190       200       210       220       230    
pF1KB5 QDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTT
            :   .:::             ::.  . .:                  .::. :.
NP_003 APRDTG---AFDA-------------VGEVEAWHR------------------NCIAYTS
         200                       210                         220 

          240       250       260       270       280       290    
pF1KB5 SWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPE
        :: :: .:: :.:::..: : .:   .:.:.:..:::   ... .: ::::  . .   
NP_003 PWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEA
             230       240       250       260       270       280 

          300       310       320       330       340       350    
pF1KB5 PVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCK
        . :: :::.:...:.::::: :.:.::: :  ..:. . :.: ::  ::..:. :..: 
NP_003 SMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACF
             290       300       310       320       330       340 

          360       370       380       
pF1KB5 CNYNCPHANEAAFPFYRLFNDIHKFRD      
       :: .: . :.       .: :.... :      
NP_003 CNLSCRNPND-------IFADLESYPDFSEIAN
             350              360       

>>XP_011534525 (OMIM: 208230,603400) PREDICTED: WNT1-ind  (160 aa)
 initn: 497 init1: 255 opt: 474  Z-score: 393.2  bits: 80.2 E(85289): 3.7e-15
Smith-Waterman score: 474; 40.7% identity (74.1% similar) in 135 aa overlap (227-359:13-147)

        200       210       220       230       240       250      
pF1KB5 ELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNP
                                     .::.::.:.:. ::.::: :::.::::.: 
XP_011                   MPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGISNRVTNENS
                                 10        20        30        40  

        260       270       280         290       300       310    
pF1KB5 ECRLVKETRICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYC
       .:.. :: :.: ..:: . . ...:  ::: :. : .  .  .:...:: :...:.: .:
XP_011 NCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFC
             50        60        70        80        90       100  

          320       330       340       350       360       370    
pF1KB5 GSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFN
       : :.: ::: :. .. . ..: : .  .:. ... : :: :. ::               
XP_011 GICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIFSELKIL  
            110       120       130       140       150       160  

          380 
pF1KB5 DIHKFRD

>>XP_011534522 (OMIM: 208230,603400) PREDICTED: WNT1-ind  (354 aa)
 initn: 855 init1: 396 opt: 416  Z-score: 343.6  bits: 72.2 E(85289): 2.1e-12
Smith-Waterman score: 825; 36.2% identity (61.4% similar) in 337 aa overlap (26-359:48-341)

                    10        20        30        40        50     
pF1KB5      MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKV
                                     :   :.:: . :.: :::.::::::::::.
XP_011 CCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKI
        20        30        40        50        60        70       

          60        70        80         90       100       110    
pF1KB5 CAKQLNEDCSKTQPCDHTKGLECNFGASSTALK-GICRAQSEGRPCEYNSRIYQNGESFQ
       :::: .: :.... ::  ::: :.....    . :.: :   .  ::.:.  :.::. ::
XP_011 CAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVC-AYLVAVGCEFNQVHYHNGQVFQ
        80        90       100       110        120       130      

          120       130       140       150       160       170    
pF1KB5 PNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMED
       ::   .: :..::.:: ::      .:          :..:. :                
XP_011 PNPLFSCLCVSGAIGCTPLF-----IP----------KLAGSHC----------------
        140       150                      160                     

          180       190       200       210       220       230    
pF1KB5 QDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTT
        .:  : . . : :.  :    : .    ..: : .:..   : :       .::.::.:
XP_011 -SGAKGGKKS-DQSNCSL----EPLLQQLSTSYKTMPAYRNLPLI-----WKKKCLVQAT
          170        180           190       200            210    

          240       250       260       270       280         290  
pF1KB5 SWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK--KGKKCSKTKKS
       .:. ::.::: :::.::::.: .:.. :: :.: ..:: . . ...:  ::: :. : . 
XP_011 KWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQL
          220       230       240       250       260       270    

            300       310       320       330       340       350  
pF1KB5 PEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQS
        .  .:...:: :...:.: .:: :.: ::: :. .. . ..: : .  .:. ... : :
XP_011 SKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITS
          280       290       300       310       320       330    

            360       370       380 
pF1KB5 CKCNYNCPHANEAAFPFYRLFNDIHKFRD
       : :. ::                      
XP_011 CVCQRNCREPGDIFSELKIL         
          340       350             

>>NP_003871 (OMIM: 208230,603400) WNT1-inducible-signali  (354 aa)
 initn: 855 init1: 396 opt: 416  Z-score: 343.6  bits: 72.2 E(85289): 2.1e-12
Smith-Waterman score: 825; 36.2% identity (61.4% similar) in 337 aa overlap (26-359:48-341)

                    10        20        30        40        50     
pF1KB5      MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKV
                                     :   :.:: . :.: :::.::::::::::.
NP_003 CCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKI
        20        30        40        50        60        70       

          60        70        80         90       100       110    
pF1KB5 CAKQLNEDCSKTQPCDHTKGLECNFGASSTALK-GICRAQSEGRPCEYNSRIYQNGESFQ
       :::: .: :.... ::  ::: :.....    . :.: :   .  ::.:.  :.::. ::
NP_003 CAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVC-AYLVAVGCEFNQVHYHNGQVFQ
        80        90       100       110        120       130      

          120       130       140       150       160       170    
pF1KB5 PNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMED
       ::   .: :..::.:: ::      .:          :..:. :                
NP_003 PNPLFSCLCVSGAIGCTPLF-----IP----------KLAGSHC----------------
        140       150                      160                     

          180       190       200       210       220       230    
pF1KB5 QDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTT
        .:  : . . : :.  :    : .    ..: : .:..   : :       .::.::.:
NP_003 -SGAKGGKKS-DQSNCSL----EPLLQQLSTSYKTMPAYRNLPLI-----WKKKCLVQAT
          170        180           190       200            210    

          240       250       260       270       280         290  
pF1KB5 SWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK--KGKKCSKTKKS
       .:. ::.::: :::.::::.: .:.. :: :.: ..:: . . ...:  ::: :. : . 
NP_003 KWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQL
          220       230       240       250       260       270    

            300       310       320       330       340       350  
pF1KB5 PEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQS
        .  .:...:: :...:.: .:: :.: ::: :. .. . ..: : .  .:. ... : :
NP_003 SKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITS
          280       290       300       310       320       330    

            360       370       380 
pF1KB5 CKCNYNCPHANEAAFPFYRLFNDIHKFRD
       : :. ::                      
NP_003 CVCQRNCREPGDIFSELKIL         
          340       350             




381 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 21:12:18 2016 done: Sat Nov  5 21:12:19 2016
 Total Scan time:  8.460 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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