Result of FASTA (omim) for pF1KB9865
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9865, 432 aa
  1>>>pF1KB9865 432 - 432 aa - 432 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1288+/-0.000441; mu= 17.7239+/- 0.027
 mean_var=63.2883+/-12.629, 0's: 0 Z-trim(109.2): 71  B-trim: 111 in 2/49
 Lambda= 0.161218
 statistics sampled from 17235 (17306) to 17235 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.203), width:  16
 Scan time:  8.060

The best scores are:                                      opt bits E(85289)
XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 2851 672.4 6.2e-193
NP_066292 (OMIM: 602323) ATP-sensitive inward rect ( 433) 2851 672.4 6.2e-193
XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 2851 672.4 6.2e-193
NP_001181887 (OMIM: 613236,613239) inward rectifie ( 433) 2805 661.7  1e-189
XP_005276976 (OMIM: 613236,613239) PREDICTED: inwa ( 535) 2805 661.7 1.2e-189
NP_000882 (OMIM: 170390,600681,609622,613980) inwa ( 427) 2033 482.1 1.2e-135
NP_037480 (OMIM: 603953) ATP-sensitive inward rect ( 436) 1552 370.3 5.6e-102
NP_004972 (OMIM: 600504) inward rectifier potassiu ( 445) 1421 339.8 8.4e-93
NP_690607 (OMIM: 600504) inward rectifier potassiu ( 445) 1421 339.8 8.4e-93
XP_016856736 (OMIM: 600932) PREDICTED: G protein-a ( 450) 1322 316.8 7.3e-86
NP_004974 (OMIM: 600932) G protein-activated inwar ( 393) 1320 316.3   9e-86
NP_000881 (OMIM: 600734,613485,613677) G protein-a ( 419) 1288 308.8 1.6e-83
XP_011541111 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1288 308.8 1.6e-83
XP_011541112 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1288 308.8 1.6e-83
NP_002231 (OMIM: 600877,614098) G protein-activate ( 423) 1272 305.1 2.2e-82
NP_002230 (OMIM: 601534) G protein-activated inwar ( 501) 1220 293.1 1.1e-78
NP_000516 (OMIM: 125853,600937,601820,606176,61058 ( 390) 1142 274.9 2.6e-73
NP_000211 (OMIM: 241200,600359) ATP-sensitive inwa ( 391) 1104 266.0 1.2e-70
NP_722448 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1101 265.3 1.8e-70
NP_722450 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1101 265.3 1.8e-70
NP_722451 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1101 265.3 1.8e-70
NP_722449 (OMIM: 241200,600359) ATP-sensitive inwa ( 389) 1101 265.3 1.9e-70
XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1081 260.7 5.2e-69
NP_004973 (OMIM: 600935) ATP-sensitive inward rect ( 424) 1081 260.7 5.2e-69
XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1081 260.7 5.2e-69
XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1081 260.7 5.2e-69
XP_016880102 (OMIM: 605722) PREDICTED: inward rect ( 418) 1073 258.8 1.9e-68
NP_001278553 (OMIM: 605722) inward rectifier potas ( 418) 1073 258.8 1.9e-68
XP_011523083 (OMIM: 605722) PREDICTED: inward rect ( 418) 1073 258.8 1.9e-68
NP_001278554 (OMIM: 605722) inward rectifier potas ( 418) 1073 258.8 1.9e-68
NP_001257351 (OMIM: 605722) inward rectifier potas ( 418) 1073 258.8 1.9e-68
XP_006721949 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
XP_016880101 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
NP_001278552 (OMIM: 605722) inward rectifier potas ( 453) 1073 258.9   2e-68
XP_006721950 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
XP_016880100 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
XP_016880099 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
XP_006721948 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
NP_733938 (OMIM: 605722) inward rectifier potassiu ( 453) 1073 258.9   2e-68
XP_016880098 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
NP_733937 (OMIM: 605722) inward rectifier potassiu ( 453) 1073 258.9   2e-68
NP_061128 (OMIM: 605722) inward rectifier potassiu ( 453) 1073 258.9   2e-68
NP_001278551 (OMIM: 605722) inward rectifier potas ( 453) 1073 258.9   2e-68
XP_005257394 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9   2e-68
NP_001247438 (OMIM: 601534) G protein-activated in ( 308) 1019 246.2 8.7e-65
NP_001263364 (OMIM: 602106) ATP-sensitive inward r ( 375)  956 231.6 2.6e-60
XP_016883832 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375)  956 231.6 2.6e-60
XP_006724065 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375)  956 231.6 2.6e-60
NP_001263367 (OMIM: 602106) ATP-sensitive inward r ( 375)  956 231.6 2.6e-60
NP_733932 (OMIM: 602106) ATP-sensitive inward rect ( 375)  956 231.6 2.6e-60


>>XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensitive i  (433 aa)
 initn: 2217 init1: 2217 opt: 2851  Z-score: 3584.8  bits: 672.4 E(85289): 6.2e-193
Smith-Waterman score: 2851; 98.6% identity (99.1% similar) in 433 aa overlap (1-432:1-433)

               10        20        30        40        50        60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
              250       260       270       280       290       300

              310       320       330        340       350         
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
       ::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
XP_011 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
       :::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
XP_011 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
              370       380       390       400       410       420

     420       430  
pF1KB9 VLEQRPYRRESEI
       :::::::::::::
XP_011 VLEQRPYRRESEI
              430   

>>NP_066292 (OMIM: 602323) ATP-sensitive inward rectifie  (433 aa)
 initn: 2217 init1: 2217 opt: 2851  Z-score: 3584.8  bits: 672.4 E(85289): 6.2e-193
Smith-Waterman score: 2851; 98.6% identity (99.1% similar) in 433 aa overlap (1-432:1-433)

               10        20        30        40        50        60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
              250       260       270       280       290       300

              310       320       330        340       350         
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
       ::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
NP_066 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
       :::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
NP_066 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
              370       380       390       400       410       420

     420       430  
pF1KB9 VLEQRPYRRESEI
       :::::::::::::
NP_066 VLEQRPYRRESEI
              430   

>>XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensitive i  (433 aa)
 initn: 2217 init1: 2217 opt: 2851  Z-score: 3584.8  bits: 672.4 E(85289): 6.2e-193
Smith-Waterman score: 2851; 98.6% identity (99.1% similar) in 433 aa overlap (1-432:1-433)

               10        20        30        40        50        60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
              250       260       270       280       290       300

              310       320       330        340       350         
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
       ::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
XP_005 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
       :::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
XP_005 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
              370       380       390       400       410       420

     420       430  
pF1KB9 VLEQRPYRRESEI
       :::::::::::::
XP_005 VLEQRPYRRESEI
              430   

>>NP_001181887 (OMIM: 613236,613239) inward rectifier po  (433 aa)
 initn: 2180 init1: 2180 opt: 2805  Z-score: 3526.9  bits: 661.7 E(85289): 1e-189
Smith-Waterman score: 2805; 97.2% identity (98.2% similar) in 433 aa overlap (1-432:1-433)

               10        20        30        40        50        60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
       :::::::::::::: :::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
       :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.::
NP_001 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
       ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
              250       260       270       280       290       300

              310       320       330        340       350         
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
       ::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
NP_001 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
       :::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
NP_001 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
              370       380       390       400       410       420

     420       430  
pF1KB9 VLEQRPYRRESEI
       ::::::::: :::
NP_001 VLEQRPYRRGSEI
              430   

>>XP_005276976 (OMIM: 613236,613239) PREDICTED: inward r  (535 aa)
 initn: 2180 init1: 2180 opt: 2805  Z-score: 3525.6  bits: 661.7 E(85289): 1.2e-189
Smith-Waterman score: 2805; 97.2% identity (98.2% similar) in 433 aa overlap (1-432:103-535)

                                             10        20        30
pF1KB9                               MTAASRANPYSIVSSEEDGLHLVTMSGANG
                                     :::::::::::::: :::::::::::::::
XP_005 FRPCVPAPQRHGAALPGASLGVSQGPPTPGMTAASRANPYSIVSLEEDGLHLVTMSGANG
             80        90       100       110       120       130  

               40        50        60        70        80        90
pF1KB9 FGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLA
       ::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_005 FGNGKVHTRRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLA
            140       150       160       170       180       190  

              100       110       120       130       140       150
pF1KB9 FLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRC
       :::::::::.:::::::::::::::::.::::::::::::::::::::::::::::::::
XP_005 FLASWLLFGVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRC
            200       210       220       230       240       250  

              160       170       180       190       200       210
pF1KB9 VTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLC
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLC
            260       270       280       290       300       310  

              220       230       240       250       260       270
pF1KB9 LMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITI
            320       330       340       350       360       370  

              280       290       300       310       320       330
pF1KB9 LHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPV
            380       390       400       410       420       430  

               340       350       360       370       380         
pF1KB9 LFE-KNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEED
       ::: :::::::: ::::::::::::::::::::::::::: ::::::.::::::::::::
XP_005 LFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEED
            440       450       460       470       480       490  

     390       400       410       420       430  
pF1KB9 EADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI
       :::::::::::.:: :::::::::::::::::::::::: :::
XP_005 EADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYRRGSEI
            500       510       520       530     

>>NP_000882 (OMIM: 170390,600681,609622,613980) inward r  (427 aa)
 initn: 1573 init1: 1265 opt: 2033  Z-score: 2556.6  bits: 482.1 E(85289): 1.2e-135
Smith-Waterman score: 2033; 70.2% identity (88.1% similar) in 430 aa overlap (6-432:5-427)

               10        20        30          40        50        
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCRNRFVKKNGQCNIEFA
            :.: ::::::::::..:.::. ::::::::  ::::..::.:::::.:.::..: 
NP_000  MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFI
                10        20        30        40        50         

       60        70        80        90       100       110        
pF1KB9 NMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGR
       :. ::.::::::.::::::::::.::.:: :::. :::.:: .::.::. ::::. :  .
NP_000 NVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLD-ASKE
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB9 GRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIG
       :.. :: .:..: ::::::::::::::::.::::.:::.:::::: :::::::::.:.::
NP_000 GKA-CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIG
      120        130       140       150       160       170       

      180       190       200       210       220       230        
pF1KB9 AIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVT
       :.:::::.:::: .::.::::::.:.::::::::::::::::::.:::::::::.: :.:
NP_000 AVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRIT
       180       190       200       210       220       230       

      240       250       260       270       280       290        
pF1KB9 EEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVI
        ::::::::::::.::::.:.:::::::::::.::::: :::. .:.::... :::::::
NP_000 SEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVI
       240       250       260       270       280       290       

      300       310       320       330        340       350       
pF1KB9 LEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCS
       ::::::::::::: ::::::::::::::.:::::: :. ::.:: .::::::::.:: ::
NP_000 LEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCS
       300       310       320       330       340       350       

       360       370       380       390       400       410       
pF1KB9 AKDLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAG
       :.::.:.:..:  ::::::.::.:. :..:.:  .:  .. : .   :    :.:  . .
NP_000 ARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD--TPP---DIDLHNQA
       360       370       380       390       400            410  

       420       430  
pF1KB9 GGVLEQRPYRRESEI
       .  :: :: ::::::
NP_000 SVPLEPRPLRRESEI
            420       

>>NP_037480 (OMIM: 603953) ATP-sensitive inward rectifie  (436 aa)
 initn: 1623 init1: 1075 opt: 1552  Z-score: 1951.9  bits: 370.3 E(85289): 5.6e-102
Smith-Waterman score: 1607; 62.8% identity (82.3% similar) in 384 aa overlap (29-401:34-415)

                 10        20        30        40         50       
pF1KB9   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRR-RCRNRFVKKNGQCNIEF
                                     ::.. . :..   : :.:::::.:.::..:
NP_037 ARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRF
            10        20        30        40        50        60   

        60        70        80        90       100       110       
pF1KB9 ANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEG
       .:.  .. :::.:.::::::.:::.: :.:: .:::::::::. ::.::  ::::  :  
NP_037 VNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAP
            70        80        90       100       110         120 

       120       130       140       150       160       170       
pF1KB9 RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMI
          .::  .: .:.:::::..::::.::::.: ::::::.::  :: : :.::..:.:..
NP_037 PPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVV
             130       140       150       160       170       180 

       180       190       200       210       220       230       
pF1KB9 GAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRV
       ::.:::::.:::: .::.::.:::::::: .:::::::::::.::.:::::::::..:::
NP_037 GAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRV
             190       200       210       220       230       240 

       240       250       260       270       280       290       
pF1KB9 TEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVV
       : ::::::::. :.::::: : :::::::::::.:::: ::::. ..: .:   :::.::
NP_037 TPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVV
             250       260       270       280       290       300 

       300       310       320       330        340       350      
pF1KB9 ILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRC
       :::::::::::::: ::::: .:.:::::::::::.. .::..:: :::.:::::.:: :
NP_037 ILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVC
             310       320       330       340       350       360 

        360               370        380       390       400       
pF1KB9 SAKDLVEN--------KFLLPRA-NSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQA
       :::.: :         :  .: . ..:::.::::.   .:::: :  ..: . :      
NP_037 SAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGAA
             370       380       390       400       410       420 

       410       420       430  
pF1KB9 RHDFDRLQAGGGVLEQRPYRRESEI
                                
NP_037 SPRVLTPTLALTLPP          
             430                

>>NP_004972 (OMIM: 600504) inward rectifier potassium ch  (445 aa)
 initn: 1869 init1: 1208 opt: 1421  Z-score: 1787.1  bits: 339.8 E(85289): 8.4e-93
Smith-Waterman score: 1821; 64.5% identity (82.7% similar) in 440 aa overlap (33-432:7-445)

             10        20        30         40        50        60 
pF1KB9 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
                                     ::..:. ::. ::::::::::::. :::..
NP_004                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                       10        20        30      

              70        80        90       100       110           
pF1KB9 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
NP_004 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
         40        50        60        70        80        90      

             120             130       140       150       160     
pF1KB9 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
NP_004 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
        100       110       120       130       140       150      

         170       180       190       200       210       220     
pF1KB9 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
NP_004 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
        160       170       180       190       200       210      

         230       240       250       260       270       280     
pF1KB9 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
NP_004 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
        220       230       240       250       260       270      

         290       300       310       320       330        340    
pF1KB9 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHF
       ..::..:::::::::::::::::::::::::::.:::::::::::.:: :..::.:: .:
NP_004 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
        280       290       300       310       320       330      

          350       360            370       380       390         
pF1KB9 HKTYEVPSTPRCSAKDLVENKFLL-----PRANSFCYKNELAFLSRDEEDEAD-------
       :::::: .:: :::..: :.:. .     :  ..:::.::::..:..::.  .       
NP_004 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
        340       350       360       370       380       390      

                 400            410       420       430  
pF1KB9 -----GDQDGRSRE-GLIPQ---ARH-DFDRLQAGGGVLEQRPYRRESEI
            : . : ..: :.: .   . : :..:.::.   :..  ::::: :
NP_004 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
        400       410       420       430        440     

>>NP_690607 (OMIM: 600504) inward rectifier potassium ch  (445 aa)
 initn: 1869 init1: 1208 opt: 1421  Z-score: 1787.1  bits: 339.8 E(85289): 8.4e-93
Smith-Waterman score: 1821; 64.5% identity (82.7% similar) in 440 aa overlap (33-432:7-445)

             10        20        30         40        50        60 
pF1KB9 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
                                     ::..:. ::. ::::::::::::. :::..
NP_690                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                       10        20        30      

              70        80        90       100       110           
pF1KB9 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
NP_690 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
         40        50        60        70        80        90      

             120             130       140       150       160     
pF1KB9 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
NP_690 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
        100       110       120       130       140       150      

         170       180       190       200       210       220     
pF1KB9 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
NP_690 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
        160       170       180       190       200       210      

         230       240       250       260       270       280     
pF1KB9 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
NP_690 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
        220       230       240       250       260       270      

         290       300       310       320       330        340    
pF1KB9 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHF
       ..::..:::::::::::::::::::::::::::.:::::::::::.:: :..::.:: .:
NP_690 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
        280       290       300       310       320       330      

          350       360            370       380       390         
pF1KB9 HKTYEVPSTPRCSAKDLVENKFLL-----PRANSFCYKNELAFLSRDEEDEAD-------
       :::::: .:: :::..: :.:. .     :  ..:::.::::..:..::.  .       
NP_690 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
        340       350       360       370       380       390      

                 400            410       420       430  
pF1KB9 -----GDQDGRSRE-GLIPQ---ARH-DFDRLQAGGGVLEQRPYRRESEI
            : . : ..: :.: .   . : :..:.::.   :..  ::::: :
NP_690 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
        400       410       420       430        440     

>>XP_016856736 (OMIM: 600932) PREDICTED: G protein-activ  (450 aa)
 initn: 1274 init1: 1145 opt: 1322  Z-score: 1662.5  bits: 316.8 E(85289): 7.3e-86
Smith-Waterman score: 1322; 51.8% identity (78.4% similar) in 398 aa overlap (2-397:39-428)

                                            10        20        30 
pF1KB9                              MTAASRANPYSIVSSEEDGLHLVTMSGANGF
                                     ... : .: .  :.. :.  ..  ..:  :
XP_016 EGPLIRQTFIKPLQDPRRRLGAQRRAAGGSSSGPRRTP-GARSARPDAAAMAQENAA--F
       10        20        30        40         50        60       

               40        50        60        70        80        90
pF1KB9 GNGKVHT-RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLA
       . :. .  ::: :.:.:.:.:.::.. .:. : . :::.:.::: ::..::  ::.: ::
XP_016 SPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLA
          70        80        90        100       110       120    

              100       110       120       130       140       150
pF1KB9 FLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRC
       .  .::.:: :.:.:: ..::::  :  . :::: ...::.:::::::::.:::::: : 
XP_016 YALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRV
          130       140       150       160       170       180    

              160       170       180       190       200       210
pF1KB9 VTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLC
       .:..:: .. ... :.:.: ....::.: ...:...:.::: ::.:: .:::.::::.::
XP_016 ITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLC
          190       200       210       220       230       240    

              220       230       240       250       260       270
pF1KB9 LMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITI
       ::.:::.::.:::::: .::.::. : : :::.::: : :..:::: : ::.:::::..:
XP_016 LMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVI
          250       260       270       280       290       300    

              280       290       300       310       320       330
pF1KB9 LHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPV
        :::: :::..  ::. :: ::::::::::::::::.:: :::::::..:.::::::  :
XP_016 SHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSV
          310       320       330       340       350       360    

               340       350       360       370       380         
pF1KB9 L-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEED
       : .: . :..::  ::.:.::: :: :::..:.:      : ..  : .  . :..  :.
XP_016 LTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAA---ARLDAHLYWSIPSRLDEKVEE
          370       380        390          400       410       420

     390       400       410       420       430  
pF1KB9 EADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI
       :. :.  :                                   
XP_016 EGAGEGAGGEAGADKEQNGCLPPPESESKV             
              430       440       450             




432 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:36:38 2016 done: Sat Nov  5 02:36:39 2016
 Total Scan time:  8.060 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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