Result of FASTA (omim) for pF1KB8168
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8168, 304 aa
  1>>>pF1KB8168 304 - 304 aa - 304 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.6503+/-0.000352; mu= 6.2577+/- 0.022
 mean_var=172.6781+/-36.045, 0's: 0 Z-trim(120.8): 43  B-trim: 2431 in 2/52
 Lambda= 0.097601
 statistics sampled from 36460 (36538) to 36460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.428), width:  16
 Scan time:  8.940

The best scores are:                                      opt bits E(85289)
NP_036390 (OMIM: 602953) hairy/enhancer-of-split r ( 304) 2004 293.7 3.1e-79
NP_001035798 (OMIM: 602953) hairy/enhancer-of-spli ( 308) 1986 291.2 1.8e-78
NP_001269780 (OMIM: 602953) hairy/enhancer-of-spli ( 214) 1330 198.7 8.7e-51
NP_036391 (OMIM: 604674) hairy/enhancer-of-split r ( 337)  853 131.7   2e-30
XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhan ( 291)  747 116.7 5.7e-26
XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhan ( 291)  747 116.7 5.7e-26
XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhan ( 291)  747 116.7 5.7e-26
NP_055386 (OMIM: 609034) hairy/enhancer-of-split r ( 328)  745 116.4 7.5e-26
XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhan ( 300)  695 109.4 9.3e-24
NP_005515 (OMIM: 139605) transcription factor HES- ( 280)  352 61.0   3e-09
NP_066993 (OMIM: 608060) transcription factor HES- ( 221)  311 55.2 1.4e-07
NP_001135939 (OMIM: 608060) transcription factor H ( 247)  301 53.8   4e-07
NP_061115 (OMIM: 610331) transcription cofactor HE ( 224)  228 43.5 0.00047
NP_001136325 (OMIM: 610331) transcription cofactor ( 222)  223 42.8 0.00075
XP_005244828 (OMIM: 608060) PREDICTED: transcripti ( 189)  214 41.5  0.0016
NP_001010926 (OMIM: 607348) transcription factor H ( 166)  211 41.0   0.002
NP_115969 (OMIM: 608059,613686) transcription fact ( 225)  208 40.7  0.0033
NP_061962 (OMIM: 609970) transcription factor HES- ( 173)  198 39.2  0.0072


>>NP_036390 (OMIM: 602953) hairy/enhancer-of-split relat  (304 aa)
 initn: 2004 init1: 2004 opt: 2004  Z-score: 1543.6  bits: 293.7 E(85289): 3.1e-79
Smith-Waterman score: 2004; 99.7% identity (100.0% similar) in 304 aa overlap (1-304:1-304)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
       ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_036 LPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
              250       260       270       280       290       300

           
pF1KB8 IGAF
       ::::
NP_036 IGAF
           

>>NP_001035798 (OMIM: 602953) hairy/enhancer-of-split re  (308 aa)
 initn: 1497 init1: 1497 opt: 1986  Z-score: 1529.8  bits: 291.2 E(85289): 1.8e-78
Smith-Waterman score: 1986; 98.4% identity (98.7% similar) in 308 aa overlap (1-304:1-308)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
               10        20        30        40        50        60

               70        80            90       100       110      
pF1KB8 RRDRINNSLSELRRLVPSAFEKQ----GSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
       :::::::::::::::::::::::    :::::::::::::::::::::::::::::::::
NP_001 RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB8 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB8 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB8 LGPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
       ::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 LGPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
              250       260       270       280       290       300

        300    
pF1KB8 WGTEIGAF
       ::::::::
NP_001 WGTEIGAF
               

>>NP_001269780 (OMIM: 602953) hairy/enhancer-of-split re  (214 aa)
 initn: 1329 init1: 1329 opt: 1330  Z-score: 1032.7  bits: 198.7 E(85289): 8.7e-51
Smith-Waterman score: 1330; 90.8% identity (95.4% similar) in 217 aa overlap (88-304:3-214)

        60        70        80        90       100       110       
pF1KB8 EKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHA
                                     ::. ... ..  .:     .: .:::::::
NP_001                             MPLEERNVFWLSKGNL-----TGDQGYFDAHA
                                           10             20       

       120       130       140       150       160       170       
pF1KB8 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
        30        40        50        60        70        80       

       180       190       200       210       220       230       
pF1KB8 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
        90       100       110       120       130       140       

       240       250       260       270       280       290       
pF1KB8 GPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
       :::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_001 GPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
       150       160       170       180       190       200       

       300    
pF1KB8 GTEIGAF
       :::::::
NP_001 GTEIGAF
       210    

>>NP_036391 (OMIM: 604674) hairy/enhancer-of-split relat  (337 aa)
 initn: 894 init1: 793 opt: 853  Z-score: 667.1  bits: 131.7 E(85289): 2e-30
Smith-Waterman score: 981; 54.1% identity (72.6% similar) in 340 aa overlap (1-302:1-335)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       :::   : ..:.:..::::.: .:.   . . ::..   ::::.:::.:::.::::::::
NP_036 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
       :::::::::::::::::.::::::::::::::::::::::::::...:::::::::::::
NP_036 RRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAM
      60        70        80        90       100       110         

              130       140       150       160           170      
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLG
       :. :.::::::.::::::: .::::.::::::::::::.. :.:::::    : ::    
NP_036 DFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP
     120       130       140       150       160       170         

          180       190       200            210       220         
pF1KB8 HIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEA
         :  :...: : :     :: :.. :.. .:     :.: . : : . : .:   : ..
NP_036 LHPHHWAAAFHHLPA---ALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS
     180       190          200       210       220       230      

        230        240       250       260            270          
pF1KB8 PALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA--
        ::: : .::..: : :. ::  .::  . ...:. ..    ::.:: :.: .: :::  
NP_036 -ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAA
         240       250       260       270       280       290     

             280              290         300    
pF1KB8 -------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
              .::       :.: :...   .:::::::::.:  
NP_036 AVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
         300       310       320       330       

>>XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhancer-  (291 aa)
 initn: 793 init1: 692 opt: 747  Z-score: 587.3  bits: 116.7 E(85289): 5.7e-26
Smith-Waterman score: 875; 55.6% identity (72.7% similar) in 293 aa overlap (48-302:1-289)

        20        30        40        50        60        70       
pF1KB8 TIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVP
                                     .:::.:::::::::::::::::::::::::
XP_016                               MARKKRRGIIEKRRRDRINNSLSELRRLVP
                                             10        20        30

        80        90       100       110       120       130       
pF1KB8 SAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARY
       .::::::::::::::::::::::::::...::::::::::::::. :.::::::.:::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
               40        50        60        70        80        90

       140       150       160           170         180       190 
pF1KB8 LSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLGHIP--WGTVFGHHPHIA
       :: .::::.::::::::::::.. :.:::::    : ::      :  :...: : :   
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAA-
              100       110       120       130       140          

             200            210       220          230        240  
pF1KB8 HPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEAPALRAPPSGSLGP-VLP
         :: :.. :.. .:     :.: . : : . : .:   : .. ::: : .::..: : :
XP_016 --LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS-ALRMPSTGSVAPCVPP
       150       160       170       180       190        200      

            250       260            270                280        
pF1KB8 VVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA---------LSP-------
       . ::  .::  . ...:. ..    ::.:: :.: .: :::         .::       
XP_016 LSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSAT
        210       220       230       240       250       260      

             290         300    
pF1KB8 SAPTQAANL--GKPYRPWGTEIGAF
       :.: :...   .:::::::::.:  
XP_016 SSPQQTSSGTNNKPYRPWGTEVGAF
        270       280       290 

>>XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhancer-  (291 aa)
 initn: 793 init1: 692 opt: 747  Z-score: 587.3  bits: 116.7 E(85289): 5.7e-26
Smith-Waterman score: 875; 55.6% identity (72.7% similar) in 293 aa overlap (48-302:1-289)

        20        30        40        50        60        70       
pF1KB8 TIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVP
                                     .:::.:::::::::::::::::::::::::
XP_016                               MARKKRRGIIEKRRRDRINNSLSELRRLVP
                                             10        20        30

        80        90       100       110       120       130       
pF1KB8 SAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARY
       .::::::::::::::::::::::::::...::::::::::::::. :.::::::.:::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
               40        50        60        70        80        90

       140       150       160           170         180       190 
pF1KB8 LSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLGHIP--WGTVFGHHPHIA
       :: .::::.::::::::::::.. :.:::::    : ::      :  :...: : :   
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAA-
              100       110       120       130       140          

             200            210       220          230        240  
pF1KB8 HPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEAPALRAPPSGSLGP-VLP
         :: :.. :.. .:     :.: . : : . : .:   : .. ::: : .::..: : :
XP_016 --LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS-ALRMPSTGSVAPCVPP
       150       160       170       180       190        200      

            250       260            270                280        
pF1KB8 VVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA---------LSP-------
       . ::  .::  . ...:. ..    ::.:: :.: .: :::         .::       
XP_016 LSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSAT
        210       220       230       240       250       260      

             290         300    
pF1KB8 SAPTQAANL--GKPYRPWGTEIGAF
       :.: :...   .:::::::::.:  
XP_016 SSPQQTSSGTNNKPYRPWGTEVGAF
        270       280       290 

>>XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhancer-  (291 aa)
 initn: 793 init1: 692 opt: 747  Z-score: 587.3  bits: 116.7 E(85289): 5.7e-26
Smith-Waterman score: 875; 55.6% identity (72.7% similar) in 293 aa overlap (48-302:1-289)

        20        30        40        50        60        70       
pF1KB8 TIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVP
                                     .:::.:::::::::::::::::::::::::
XP_016                               MARKKRRGIIEKRRRDRINNSLSELRRLVP
                                             10        20        30

        80        90       100       110       120       130       
pF1KB8 SAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARY
       .::::::::::::::::::::::::::...::::::::::::::. :.::::::.:::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
               40        50        60        70        80        90

       140       150       160           170         180       190 
pF1KB8 LSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLGHIP--WGTVFGHHPHIA
       :: .::::.::::::::::::.. :.:::::    : ::      :  :...: : :   
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAA-
              100       110       120       130       140          

             200            210       220          230        240  
pF1KB8 HPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEAPALRAPPSGSLGP-VLP
         :: :.. :.. .:     :.: . : : . : .:   : .. ::: : .::..: : :
XP_016 --LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS-ALRMPSTGSVAPCVPP
       150       160       170       180       190        200      

            250       260            270                280        
pF1KB8 VVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA---------LSP-------
       . ::  .::  . ...:. ..    ::.:: :.: .: :::         .::       
XP_016 LSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSAT
        210       220       230       240       250       260      

             290         300    
pF1KB8 SAPTQAANL--GKPYRPWGTEIGAF
       :.: :...   .:::::::::.:  
XP_016 SSPQQTSSGTNNKPYRPWGTEVGAF
        270       280       290 

>>NP_055386 (OMIM: 609034) hairy/enhancer-of-split relat  (328 aa)
 initn: 723 init1: 565 opt: 745  Z-score: 585.1  bits: 116.4 E(85289): 7.5e-26
Smith-Waterman score: 745; 48.4% identity (69.1% similar) in 304 aa overlap (1-288:1-290)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       ::: . : :.::.: :  :.: .:     :.::.    .:  .:::. :::.::::::::
NP_055 MKRPK-EPSGSDGESDGPIDVGQE-----GQLSQMARPLSTPSSSQMQARKKRRGIIEKR
                10        20             30        40        50    

               70        80        90       100       110       120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
       ::::::.::::::::::.:::::::.::::::.::::::::::::..:: :.:::.:::.
NP_055 RRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAV
           60        70        80        90       100       110    

              130       140        150       160       170         
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIP
       :.::.::::::.:: :::...:: .. .::.:.::.::::.::.. : .    . :.   
NP_055 DFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPA
          120       130       140       150       160       170    

     180        190       200       210       220       230        
pF1KB8 WGTVFGHH-PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPP----S
       :   : :  : .  : :  .:  .  : . ::. :   :  . :.:  ::::. :    .
NP_055 WPWSFFHSCPGL--PAL--SNQLAILGRVPSPVLP---GVSSPAYP-IPALRTAPLRRAT
          180           190       200          210        220      

              240        250       260         270          280    
pF1KB8 GSLGP----VLPVV-TSASKLSPPLLSSVASLSVFPFSFG--SFH---LLSPNALSPSAP
       : . :    :::   .:... . ::   .. . : : : .  : :   ::. .. .: .:
NP_055 GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGP
        230       240       250       260       270       280      

          290       300                          
pF1KB8 TQAANLGKPYRPWGTEIGAF                      
       : .:                                      
NP_055 TGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
        290       300       310       320        

>>XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhancer-  (300 aa)
 initn: 703 init1: 545 opt: 695  Z-score: 547.5  bits: 109.4 E(85289): 9.3e-24
Smith-Waterman score: 695; 49.2% identity (70.7% similar) in 266 aa overlap (39-288:5-262)

       10        20        30        40        50        60        
pF1KB8 SSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNS
                                     .:  .:::. :::..:::::::::::::.:
XP_005                           MARPLSTPSSSQMQARKKHRGIIEKRRRDRINSS
                                         10        20        30    

       70        80        90       100       110       120        
pF1KB8 LSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFR
       :::::::::.:::::::.::::::.::::::::::::..:: :.:::.:::.:.::.:::
XP_005 LSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFR
           40        50        60        70        80        90    

      130       140        150       160       170       180       
pF1KB8 ECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIPWGTVFGHH
       :::.:: :::...:: .. .::.:.::.::::.::.. : .    . :.   :   : : 
XP_005 ECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHS
          100       110       120       130       140       150    

        190       200       210       220       230                
pF1KB8 -PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPP----SGSLGP---
        : .  : :  .:  .  : . ::. :   :  . :.:  ::::. :    .: . :   
XP_005 CPGL--PAL--SNQLAILGRVPSPVLP---GVSSPAYP-IPALRTAPLRRATGIILPARR
            160         170          180        190       200      

      240        250       260         270          280       290  
pF1KB8 -VLPVV-TSASKLSPPLLSSVASLSVFPFSFG--SFH---LLSPNALSPSAPTQAANLGK
        :::   .:... . ::   .. . : : : .  : :   ::. .. .: .:: .:    
XP_005 NVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVA
        210       220       230       240       250       260      

            300                          
pF1KB8 PYRPWGTEIGAF                      
                                         
XP_005 VPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
        270       280       290       300

>>NP_005515 (OMIM: 139605) transcription factor HES-1 [H  (280 aa)
 initn: 390 init1: 151 opt: 352  Z-score: 286.9  bits: 61.0 E(85289): 3e-09
Smith-Waterman score: 352; 33.3% identity (58.8% similar) in 291 aa overlap (21-297:6-278)

               10        20        30          40        50        
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSM--SPTTSSQILARKRRRGIIE
                           .::.:..  .   .....   .: :.:.   ::  . :.:
NP_005                MPADIMEKNSSSPVAATPASVNTTPDKPKTASE--HRKSSKPIME
                              10        20        30          40   

       60        70        80          90       100       110      
pF1KB8 KRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
       :::: :::.:::.:. :. .:..:..:  .:::::.::.::: ::. :. :   . ... 
NP_005 KRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTD
            50        60        70        80        90       100   

        120       130       140       150       160         170    
pF1KB8 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAAS--GA-HA
         ..     :: ::. ::.:.::  ::...   .:.::..:: :  .: .: .  :  : 
NP_005 PSVLGKYRAGFSECMNEVTRFLSTCEGVNTE--VRTRLLGHLANCMTQINAMTYPGQPHP
           110       120       130         140       150       160 

           180            190       200       210       220        
pF1KB8 GLGHIPWGTVFG-----HHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPA
       .: . :     :     : :    : :.:  :    :  :.:       .:::   ::  
NP_005 AL-QAPPPPPPGPGGPQHAPFAPPPPLVPIPG----G--AAPPPGGAPCKLGSQAGEA--
              170       180       190             200       210    

      230       240       250       260        270       280       
pF1KB8 LRAPPSGSLGPVLPVVTSASKLSPPLLSSVASLSVFP-FSFGSFHLLSPNALSPSA-PTQ
         :   :..  :.:.  .   .  :  . . :  :.: .. .:   ..:::.:::. :. 
NP_005 --AKVFGGF-QVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSL
               220       230       240       250       260         

        290       300    
pF1KB8 AANLGKPYRPWGTEIGAF
       .:.  . .:::       
NP_005 TAD--SMWRPWRN     
     270         280     




304 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:16:29 2016 done: Sat Nov  5 02:16:31 2016
 Total Scan time:  8.940 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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