Result of FASTA (ccds) for pF1KB8168
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8168, 304 aa
  1>>>pF1KB8168 304 - 304 aa - 304 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.6372+/-0.000878; mu= 6.4596+/- 0.053
 mean_var=162.0397+/-32.515, 0's: 0 Z-trim(113.1): 34  B-trim: 0 in 0/50
 Lambda= 0.100754
 statistics sampled from 13768 (13801) to 13768 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.424), width:  16
 Scan time:  3.000

The best scores are:                                      opt bits E(32554)
CCDS6225.1 HEY1 gene_id:23462|Hs108|chr8           ( 304) 2004 302.6 2.5e-82
CCDS43749.1 HEY1 gene_id:23462|Hs108|chr8          ( 308) 1986 300.0 1.5e-81
CCDS64915.1 HEY1 gene_id:23462|Hs108|chr8          ( 214) 1330 204.5 5.9e-53
CCDS5131.1 HEY2 gene_id:23493|Hs108|chr6           ( 337)  853 135.3 6.2e-32
CCDS439.1 HEYL gene_id:26508|Hs108|chr1            ( 328)  738 118.6 6.5e-27
CCDS75214.1 HELT gene_id:391723|Hs108|chr4         ( 242)  368 64.7   8e-11


>>CCDS6225.1 HEY1 gene_id:23462|Hs108|chr8                (304 aa)
 initn: 2004 init1: 2004 opt: 2004  Z-score: 1591.6  bits: 302.6 E(32554): 2.5e-82
Smith-Waterman score: 2004; 99.7% identity (100.0% similar) in 304 aa overlap (1-304:1-304)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 GTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
       ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS62 LPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTE
              250       260       270       280       290       300

           
pF1KB8 IGAF
       ::::
CCDS62 IGAF
           

>>CCDS43749.1 HEY1 gene_id:23462|Hs108|chr8               (308 aa)
 initn: 1497 init1: 1497 opt: 1986  Z-score: 1577.4  bits: 300.0 E(32554): 1.5e-81
Smith-Waterman score: 1986; 98.4% identity (98.7% similar) in 308 aa overlap (1-304:1-308)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
               10        20        30        40        50        60

               70        80            90       100       110      
pF1KB8 RRDRINNSLSELRRLVPSAFEKQ----GSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
       :::::::::::::::::::::::    :::::::::::::::::::::::::::::::::
CCDS43 RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB8 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB8 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGS
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB8 LGPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
       ::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS43 LGPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRP
              250       260       270       280       290       300

        300    
pF1KB8 WGTEIGAF
       ::::::::
CCDS43 WGTEIGAF
               

>>CCDS64915.1 HEY1 gene_id:23462|Hs108|chr8               (214 aa)
 initn: 1329 init1: 1329 opt: 1330  Z-score: 1064.2  bits: 204.5 E(32554): 5.9e-53
Smith-Waterman score: 1330; 90.8% identity (95.4% similar) in 217 aa overlap (88-304:3-214)

        60        70        80        90       100       110       
pF1KB8 EKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHA
                                     ::. ... ..  .:     .: .:::::::
CCDS64                             MPLEERNVFWLSKGNL-----TGDQGYFDAHA
                                           10             20       

       120       130       140       150       160       170       
pF1KB8 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGH
        30        40        50        60        70        80       

       180       190       200       210       220       230       
pF1KB8 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 IPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSL
        90       100       110       120       130       140       

       240       250       260       270       280       290       
pF1KB8 GPVLPVVTSASKLSPPLLSSVASLSVFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
       :::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
CCDS64 GPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPW
       150       160       170       180       190       200       

       300    
pF1KB8 GTEIGAF
       :::::::
CCDS64 GTEIGAF
       210    

>>CCDS5131.1 HEY2 gene_id:23493|Hs108|chr6                (337 aa)
 initn: 894 init1: 793 opt: 853  Z-score: 686.8  bits: 135.3 E(32554): 6.2e-32
Smith-Waterman score: 981; 54.1% identity (72.6% similar) in 340 aa overlap (1-302:1-335)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       :::   : ..:.:..::::.: .:.   . . ::..   ::::.:::.:::.::::::::
CCDS51 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
       :::::::::::::::::.::::::::::::::::::::::::::...:::::::::::::
CCDS51 RRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAM
      60        70        80        90       100       110         

              130       140       150       160           170      
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLG
       :. :.::::::.::::::: .::::.::::::::::::.. :.:::::    : ::    
CCDS51 DFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP
     120       130       140       150       160       170         

          180       190       200            210       220         
pF1KB8 HIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEA
         :  :...: : :     :: :.. :.. .:     :.: . : : . : .:   : ..
CCDS51 LHPHHWAAAFHHLPA---ALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS
     180       190          200       210       220       230      

        230        240       250       260            270          
pF1KB8 PALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSV----FPFSF-GSFHLLSPNA--
        ::: : .::..: : :. ::  .::  . ...:. ..    ::.:: :.: .: :::  
CCDS51 -ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAA
         240       250       260       270       280       290     

             280              290         300    
pF1KB8 -------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
              .::       :.: :...   .:::::::::.:  
CCDS51 AVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
         300       310       320       330       

>>CCDS439.1 HEYL gene_id:26508|Hs108|chr1                 (328 aa)
 initn: 716 init1: 558 opt: 738  Z-score: 596.6  bits: 118.6 E(32554): 6.5e-27
Smith-Waterman score: 738; 48.0% identity (69.1% similar) in 304 aa overlap (1-288:1-290)

               10        20        30        40        50        60
pF1KB8 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
       ::: . : :.::.: :  :.: .:     :.::.    .:  .:::. :::..:::::::
CCDS43 MKRPK-EPSGSDGESDGPIDVGQE-----GQLSQMARPLSTPSSSQMQARKKHRGIIEKR
                10        20             30        40        50    

               70        80        90       100       110       120
pF1KB8 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
       ::::::.::::::::::.:::::::.::::::.::::::::::::..:: :.:::.:::.
CCDS43 RRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAV
           60        70        80        90       100       110    

              130       140        150       160       170         
pF1KB8 DYRSLGFRECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIP
       :.::.::::::.:: :::...:: .. .::.:.::.::::.::.. : .    . :.   
CCDS43 DFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPA
          120       130       140       150       160       170    

     180        190       200       210       220       230        
pF1KB8 WGTVFGHH-PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPP----S
       :   : :  : .  : :  .:  .  : . ::. :   :  . :.:  ::::. :    .
CCDS43 WPWSFFHSCPGL--PAL--SNQLAILGRVPSPVLP---GVSSPAYP-IPALRTAPLRRAT
          180           190       200          210        220      

              240        250       260         270          280    
pF1KB8 GSLGP----VLPVV-TSASKLSPPLLSSVASLSVFPFSFG--SFH---LLSPNALSPSAP
       : . :    :::   .:... . ::   .. . : : : .  : :   ::. .. .: .:
CCDS43 GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGP
        230       240       250       260       270       280      

          290       300                          
pF1KB8 TQAANLGKPYRPWGTEIGAF                      
       : .:                                      
CCDS43 TGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
        290       300       310       320        

>>CCDS75214.1 HELT gene_id:391723|Hs108|chr4              (242 aa)
 initn: 321 init1: 209 opt: 368  Z-score: 307.8  bits: 64.7 E(32554): 8e-11
Smith-Waterman score: 374; 34.5% identity (60.6% similar) in 249 aa overlap (44-284:2-236)

            20        30        40        50           60        70
pF1KB8 ELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRR---RGIIEKRRRDRINNSLS
                                     :...  :::    . .::::::::::  :.
CCDS75                              MSDKLKERKRTPVSHKVIEKRRRDRINRCLN
                                            10        20        30 

               80        90       100        110         120       
pF1KB8 ELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAG-GKGYFDAHALA--MDYRSLGF
       :: . :: :. ::.:.::::::::.:::..:. ::.:   .:   :. ::   .:   :.
CCDS75 ELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGY
              40        50        60        70        80        90 

       130       140       150       160       170       180       
pF1KB8 RECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPWGTVFGHH
       .::. ....::. .: ....:   .:... :.. :  : .:  :   :: .:    :...
CCDS75 HECMKNLVHYLTTVERMETKDTKYARILAFLQSKA--RLGAEPAFPPLGSLPEPD-FSYQ
             100       110       120         130       140         

       190       200       210       220       230       240       
pF1KB8 PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPVLPV-VTS
        : : : .    ::. . ... :     ::  ..  :  :.    :.    :  :: ..:
CCDS75 LHPAGPEF---AGHSPGEAAVFP-----QGSGAGPFPWPPGAARSPALPYLPSAPVPLAS
      150          160            170       180       190       200

        250       260        270       280       290       300    
pF1KB8 ASKLSPPLLSSVASLSVFPFSF-GSFHLLSPNALSPSAPTQAANLGKPYRPWGTEIGAF
        ..   :.:. : .:.   ... :  :   ::::.  .:                    
CCDS75 PAQQHSPFLTPVQGLDRHYLNLIGHAH---PNALNLHTPQHPPVL              
              210       220          230       240                




304 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:16:29 2016 done: Sat Nov  5 02:16:29 2016
 Total Scan time:  3.000 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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