Result of FASTA (ccds) for pF1KB5337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5337, 258 aa
  1>>>pF1KB5337 258 - 258 aa - 258 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2996+/-0.00069; mu= 17.0210+/- 0.042
 mean_var=111.3333+/-21.348, 0's: 0 Z-trim(114.7): 43  B-trim: 46 in 1/50
 Lambda= 0.121552
 statistics sampled from 15222 (15266) to 15222 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.469), width:  16
 Scan time:  2.680

The best scores are:                                      opt bits E(32554)
CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17        ( 258) 1897 342.5 1.8e-94
CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7          ( 259)  530 102.7 2.6e-22
CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2          ( 272)  450 88.7 4.4e-18
CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7         ( 297)  415 82.6 3.3e-16
CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7          ( 291)  398 79.7 2.6e-15
CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2         ( 325)  324 66.7 2.2e-11


>>CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17             (258 aa)
 initn: 1897 init1: 1897 opt: 1897  Z-score: 1809.7  bits: 342.5 E(32554): 1.8e-94
Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)

               10        20        30        40        50        60
pF1KB5 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG
              190       200       210       220       230       240

              250        
pF1KB5 LEPKGELDCHQLADSFRE
       ::::::::::::::::::
CCDS11 LEPKGELDCHQLADSFRE
              250        

>>CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7               (259 aa)
 initn: 537 init1: 240 opt: 530  Z-score: 514.2  bits: 102.7 E(32554): 2.6e-22
Smith-Waterman score: 530; 34.7% identity (60.1% similar) in 248 aa overlap (10-250:14-252)

                   10        20        30        40          50    
pF1KB5     MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVG--CEELVREPGCG
                    :::..  : . :    .: ::: :::: : :::.  : :..:  :::
CCDS55 MSEVPVARVWLVLLLLTVQVGVTAG-APWQCAPCSAEKLALC-PPVSASCSEVTRSAGCG
               10        20         30        40         50        

           60        70        80        90       100       110    
pF1KB5 CCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQ
       ::  ::: ::  ::: : ::. :: :    : ..:::.: .:::.:.. ..  :      
CCDS55 CCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASA------
       60        70        80        90       100       110        

          120       130       140       150          160       170 
pF1KB5 PSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTS---GGKMKVNGAPREDARPVPQ
       :   . :. :..  :   ....   . :.    ... :    .    .:.    .  . .
CCDS55 PHAAEAGS-PESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKK
            120        130       140       150       160       170 

               180       190       200       210       220         
pF1KB5 GS--CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV
        .  :. ::.:..: :: .:  . :..  . .:::..:: .: .::. ..::. : ::::
CCDS55 WKEPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCV
             180       190       200       210       220       230 

     230       240       250        
pF1KB5 DRKTGVKLPGGLEPKGELDCHQLADSFRE
          .: ..::. : .:. .:.        
CCDS55 YPWNGKRIPGSPEIRGDPNCQIYFNVQN 
             240       250          

>>CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2               (272 aa)
 initn: 623 init1: 373 opt: 450  Z-score: 438.1  bits: 88.7 E(32554): 4.4e-18
Smith-Waterman score: 658; 40.0% identity (62.9% similar) in 275 aa overlap (1-255:1-269)

               10         20        30        40         50        
pF1KB5 MLPLCLVAALLLA-AGPGPSLGDEAIHCPPCSEEKLARCRP-PVGCEELVREPGCGCCAT
       :. :  :  :: : :::. :::.  .:: ::.:. :. : : :.::: ::.::::::: :
CCDS24 MVLLTAVLLLLAAYAGPAQSLGSF-VHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMT
               10        20         30        40         50        

       60        70        80        90       100           110    
pF1KB5 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELA----EIEAIQESLQ
       :::. :. ::::: ::..:::: : .  :::::.:.::.:::..      ...  ..: .
CCDS24 CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSRE
       60        70        80        90       100       110        

          120       130          140       150       160           
pF1KB5 PSDKDEGDHPNNSFSPC---SAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARP---
         .   ..  ....::      : :    :  :  .::  .  . :  :. .. :.:   
CCDS24 HEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRII
      120       130       140       150       160       170        

       170              180       190       200       210       220
pF1KB5 -VP-------QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALD
        .:       :: :. ... .:..: ::   . . .:.   :::::.: .. :::.:.  
CCDS24 SAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYL---PNCDRKGFYKRKQCKPSRG
      180       190       200       210          220       230     

              230       240       250        
pF1KB5 GQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE
        .:: ::::: : :.::::     :...:: . .:   
CCDS24 RKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFDSSNVE
         240        250       260       270  

>>CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7              (297 aa)
 initn: 498 init1: 359 opt: 415  Z-score: 404.5  bits: 82.6 E(32554): 3.3e-16
Smith-Waterman score: 550; 35.2% identity (57.8% similar) in 270 aa overlap (13-250:31-290)

                                 10        20        30        40  
pF1KB5                   MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPV
                                     .:: ::     ...: ::. . ::.: :: 
CCDS34 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGP-----VVRCEPCDARALAQCAPPP
               10        20        30             40        50     

              50        60        70        80        90       100 
pF1KB5 G-CEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCM
       . : ::::::::::: ::::. :.:::.:: :::::::: :     .::..:. :.:.:.
CCDS34 AVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCV
          60        70        80        90       100       110     

             110       120       130                     140       
pF1KB5 ELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDR--------------RCLQKHF----
       . . .  ..  : :.    :. :  . .  : .::              :  . .:    
CCDS34 NASAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLH
         120       130       140       150       160       170     

               150       160                170       180       190
pF1KB5 AKI----RDRSTSGGKMKVNGAPR---------EDARPVPQGSCQSELHRALERLAASQS
       .::    . .. .. ..::.   .         :. : .  : :. :.. .:..:   . 
CCDS34 SKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNV
         180       190       200       210       220       230     

              200       210       220       230       240       250
pF1KB5 RTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCH
        . . ..:   ::::..: .. :::.:.   .:: ::::: : :  :::    ::. : :
CCDS34 LSPRGVHI---PNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPG-YTTKGKEDVH
         240          250       260       270        280        290

               
pF1KB5 QLADSFRE
               
CCDS34 CYSMQSK 
               

>>CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7               (291 aa)
 initn: 563 init1: 337 opt: 398  Z-score: 388.5  bits: 79.7 E(32554): 2.6e-15
Smith-Waterman score: 556; 35.6% identity (59.5% similar) in 264 aa overlap (13-250:31-284)

                                 10        20        30        40  
pF1KB5                   MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPV
                                     .:: ::     ...: ::. . ::.: :: 
CCDS55 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGP-----VVRCEPCDARALAQCAPPP
               10        20        30             40        50     

              50        60        70        80        90       100 
pF1KB5 G-CEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCM
       . : ::::::::::: ::::. :.:::.:: :::::::: :     .::..:. :.:.:.
CCDS55 AVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCV
          60        70        80        90       100       110     

             110               120       130       140             
pF1KB5 ELAEIEAIQESLQP--------SDKDEGDHPNNSFSPCSAHDRRCLQKHF----AKI---
       . . .  ..  : :        :...:    ..  ::  .  .:  . .:    .::   
CCDS55 NASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIII
         120       130       140       150       160       170     

         150       160                170       180       190      
pF1KB5 -RDRSTSGGKMKVNGAPR---------EDARPVPQGSCQSELHRALERLAASQSRTHEDL
        . .. .. ..::.   .         :. : .  : :. :.. .:..:   .  . . .
CCDS55 KKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGV
         180       190       200       210       220       230     

        200       210       220       230       240       250      
pF1KB5 YIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSF
       .:   ::::..: .. :::.:.   .:: ::::: : :  :::    ::. : :      
CCDS55 HI---PNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPG-YTTKGKEDVHCYSMQS
            240       250       260        270        280       290

         
pF1KB5 RE
         
CCDS55 K 
         

>>CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2              (325 aa)
 initn: 648 init1: 307 opt: 324  Z-score: 317.8  bits: 66.7 E(32554): 2.2e-11
Smith-Waterman score: 627; 37.9% identity (60.5% similar) in 301 aa overlap (1-258:17-315)

                               10        20         30        40   
pF1KB5                 MLPLCLVAALLLAAGPGPSLGDEAI-HCPPCSEEKLARCRPP--
                       .::: :.  :: :.: : .   :.. .::::. :.:: : ::  
CCDS42 MLPRVGCPALPLPPPPLLPLLLL--LLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV
               10        20          30        40        50        

                            50        60        70        80       
pF1KB5 --------------VGCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVE
                     . : :::::::::::..::   :  :::::::::.::::::  : :
CCDS42 APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSE
       60        70        80        90       100       110        

        90       100         110         120              130      
pF1KB5 KPLHTLMHGQGVCMEL--AEIEAIQESLQPS--DKDEG-------DHPNNSFSPCSAHDR
        ::..:. :.:.: .   ::  :  :..  .  :..::       :   : ..  ..  :
CCDS42 LPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGR
      120       130       140       150       160       170        

        140          150              160       170        180     
pF1KB5 RCLQ---KHFAKIRDRST-------SGGKMKVNGAPREDARPVPQGS-CQSELHRALERL
       . :.   :..: .:.. :       .::: ...    .  :: :  . ::.:: ..:::.
CCDS42 KPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERI
      180       190       200       210       220       230        

             190       200       210       220       230       240 
pF1KB5 AA----SQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGL
       ..    ..    : :: . :::::..: .. :::. .:.::::.::::. .::  . :. 
CCDS42 STMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAP
      240       250       260       270       280       290        

             250                  
pF1KB5 EPKGELDCHQLADSFRE          
         .:. .:: . .  .:          
CCDS42 TIRGDPECHLFYNEQQEARGVHTQRMQ
      300       310       320     




258 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:56:37 2016 done: Sat Nov  5 01:56:37 2016
 Total Scan time:  2.680 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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