Result of FASTA (omim) for pF1KB9376
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9376, 411 aa
  1>>>pF1KB9376 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5447+/-0.000405; mu= 15.9834+/- 0.025
 mean_var=68.2936+/-13.831, 0's: 0 Z-trim(111.2): 18  B-trim: 898 in 1/54
 Lambda= 0.155197
 statistics sampled from 19708 (19725) to 19708 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.231), width:  16
 Scan time:  8.000

The best scores are:                                      opt bits E(85289)
NP_001116078 (OMIM: 300257,309060) lysosome-associ ( 411) 2689 611.3 1.3e-174
NP_054701 (OMIM: 300257,309060) lysosome-associate ( 410) 2564 583.3 3.6e-166
NP_002285 (OMIM: 300257,309060) lysosome-associate ( 410) 2547 579.5  5e-165
NP_005552 (OMIM: 153330) lysosome-associated membr ( 417)  877 205.6 1.8e-52
XP_011535796 (OMIM: 153330) PREDICTED: lysosome-as ( 398)  856 200.9 4.6e-51
XP_006713649 (OMIM: 605883) PREDICTED: lysosome-as ( 394)  382 94.8 4.1e-19
XP_005247417 (OMIM: 605883) PREDICTED: lysosome-as ( 418)  382 94.8 4.3e-19
NP_055213 (OMIM: 605883) lysosome-associated membr ( 416)  361 90.1 1.1e-17
NP_001242 (OMIM: 153634) macrosialin isoform A pre ( 354)  240 63.0 1.4e-09
NP_001035148 (OMIM: 153634) macrosialin isoform B  ( 327)  238 62.5 1.8e-09
XP_011510990 (OMIM: 605883) PREDICTED: lysosome-as ( 354)  210 56.2 1.4e-07
NP_001186826 (OMIM: 614641) lysosome-associated me ( 236)  140 40.5  0.0053
NP_036393 (OMIM: 614641) lysosome-associated membr ( 280)  140 40.5  0.0062


>>NP_001116078 (OMIM: 300257,309060) lysosome-associated  (411 aa)
 initn: 2689 init1: 2689 opt: 2689  Z-score: 3255.6  bits: 611.3 E(85289): 1.3e-174
Smith-Waterman score: 2689; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411)

               10        20        30        40        50        60
pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG
              310       320       330       340       350       360

              370       380       390       400       410 
pF1KB9 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
              370       380       390       400       410 

>>NP_054701 (OMIM: 300257,309060) lysosome-associated me  (410 aa)
 initn: 2585 init1: 2438 opt: 2564  Z-score: 3104.3  bits: 583.3 E(85289): 3.6e-166
Smith-Waterman score: 2564; 95.1% identity (98.5% similar) in 411 aa overlap (1-411:1-410)

               10        20        30        40        50        60
pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG
              310       320       330       340       350       360

              370       380       390       400       410 
pF1KB9 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
       :::::.::: :.: ..:::. ::..:. ::::. :.:.:::::: .:::..
NP_054 KYSTAQECSLDDD-TILIPIIVGAGLSGLIIVIVIAYVIGRRKSYAGYQTL
              370        380       390       400       410

>>NP_002285 (OMIM: 300257,309060) lysosome-associated me  (410 aa)
 initn: 2545 init1: 2441 opt: 2547  Z-score: 3083.8  bits: 579.5 E(85289): 5e-165
Smith-Waterman score: 2547; 94.4% identity (99.0% similar) in 409 aa overlap (1-409:1-408)

               10        20        30        40        50        60
pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG
              310       320       330       340       350       360

              370       380       390       400       410 
pF1KB9 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
       :::::..::::.: :::.:.:::.::. ..:.:...:.:: .. ..::.  
NP_002 KYSTAQDCSADDD-NFLVPIAVGAALAGVLILVLLAYFIGLKHHHAGYEQF
              370        380       390       400       410

>>NP_005552 (OMIM: 153330) lysosome-associated membrane   (417 aa)
 initn: 776 init1: 289 opt: 877  Z-score: 1062.8  bits: 205.6 E(85289): 1.8e-52
Smith-Waterman score: 877; 36.0% identity (68.3% similar) in 419 aa overlap (10-411:4-417)

               10             20        30        40         50    
pF1KB9 MVCFRLFPVPGSG-----LVLVCLVLGAVRSYALELNLTDSENAT-CLYAKWQMNFTVRY
                :::.     :.:. :.:: ..  .  . .. . :.: :..:...  :.: :
NP_005       MAAPGSARRPLLLLLLLLLLGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNY
                     10        20        30        40        50    

            60        70        80         90       100       110  
pF1KB9 ET-TNKTYKTVTISDHGTVTYNGSICG-DDQNGPKIAVQFGPGFSWIANFTKAASTYSID
       .: ..    :  . . .::. : : :: .. . :.... :: : .   :::. :. ::..
NP_005 DTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQ
           60        70        80        90       100       110    

            120       130       140       150       160       170  
pF1KB9 SVSFSYNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVL
        .:: :: .:.  ::.: .: : ::. .  ::  ..  .:: : . .. :.:.    :. 
NP_005 LMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDAT
          120       130       140       150       160       170    

            180       190        200       210       220       230 
pF1KB9 VQAFVQNGTVSTNEFLCDKDKTS-TVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDT
       .::...:.. : .:  :..:. : :.::    . :::. .:.:: .: .  :.:.. : :
NP_005 IQAYLSNSSFSRGETRCEQDRPSPTTAPP---APPSPSPSPVPK-SPSVDKYNVSGTNGT
          180       190       200          210        220       230

             240            250       260       270       280      
pF1KB9 CLLATMGLQLNITQDK-----VASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVF
       ::::.::::::.: ..     :. ..::::: : ..::: .: . :.:.:     : : :
NP_005 CLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQF
              240       250       260       270       280       290

         290       300         310       320       330       340   
pF1KB9 AVK-NENRFYLKEVNISMYLVNGS--VFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAF
       ... . .::.:. ....  : ..   .:. ::..:   .: .:.:: :: :. : :. ::
NP_005 GMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAF
              300       310       320       330       340       350

           350       360       370       380       390       400   
pF1KB9 QINTFDLRVQPFNVTQGKYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRK
       ..: : . :: :.:  :.....:::  : . ..:::.::: ::. :...:.:.:..::..
NP_005 SVNIFKVWVQAFKVEGGQFGSVEECLLDEN-SMLIPIAVGGALAGLVLIVLIAYLVGRKR
              360       370       380        390       400         

           410 
pF1KB9 SRTGYQSV
       :..:::..
NP_005 SHAGYQTI
     410       

>>XP_011535796 (OMIM: 153330) PREDICTED: lysosome-associ  (398 aa)
 initn: 776 init1: 289 opt: 856  Z-score: 1037.7  bits: 200.9 E(85289): 4.6e-51
Smith-Waterman score: 856; 35.7% identity (68.2% similar) in 403 aa overlap (21-411:1-398)

               10        20        30        40         50         
pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENAT-CLYAKWQMNFTVRYET-TN
                           .: ..  .  . .. . :.: :..:...  :.: :.: ..
XP_011                     MGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNYDTKSG
                                   10        20        30        40

       60        70        80         90       100       110       
pF1KB9 KTYKTVTISDHGTVTYNGSICG-DDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFS
           :  . . .::. : : :: .. . :.... :: : .   :::. :. ::.. .:: 
XP_011 PKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFV
               50        60        70        80        90       100

       120       130       140       150       160       170       
pF1KB9 YNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFV
       :: .:.  ::.: .: : ::. .  ::  ..  .:: : . .. :.:.    :. .::..
XP_011 YNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYL
              110       120       130       140       150       160

       180       190        200       210       220       230      
pF1KB9 QNGTVSTNEFLCDKDKTS-TVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLAT
       .:.. : .:  :..:. : :.::      :::. .:.:: .: .  :.:.. : :::::.
XP_011 SNSSFSRGETRCEQDRPSPTTAPPAP---PSPSPSPVPK-SPSVDKYNVSGTNGTCLLAS
              170       180          190        200       210      

        240            250       260       270       280        290
pF1KB9 MGLQLNITQDK-----VASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVK-N
       ::::::.: ..     :. ..::::: : ..::: .: . :.:.:     : : :... .
XP_011 MGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNAS
        220       230       240       250       260       270      

              300         310       320       330       340        
pF1KB9 ENRFYLKEVNISMYLVNGS--VFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTF
        .::.:. ....  : ..   .:. ::..:   .: .:.:: :: :. : :. ::..: :
XP_011 SSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAFSVNIF
        280       290       300       310       320       330      

      350       360       370       380       390       400        
pF1KB9 DLRVQPFNVTQGKYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGY
        . :: :.:  :.....:::  : . ..:::.::: ::. :...:.:.:..::..:..::
XP_011 KVWVQAFKVEGGQFGSVEECLLDEN-SMLIPIAVGGALAGLVLIVLIAYLVGRKRSHAGY
        340       350       360        370       380       390     

      410 
pF1KB9 QSV
       :..
XP_011 QTI
          

>>XP_006713649 (OMIM: 605883) PREDICTED: lysosome-associ  (394 aa)
 initn: 266 init1:  81 opt: 382  Z-score: 464.2  bits: 94.8 E(85289): 4.1e-19
Smith-Waterman score: 395; 27.3% identity (60.5% similar) in 377 aa overlap (46-409:51-392)

          20        30        40        50          60          70 
pF1KB9 LVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNK--TYKTVTISD--HGT
                                     .:   ::.  ::.   : .:.: :   .  
XP_006 VQDIKKPVQQPAKQAPHQTLAARFMDGHITFQTAATVKIPTTTPATTKNTATTSPITYTL
               30        40        50        60        70        80

              80        90          100       110       120        
pF1KB9 VTYNGSICGDDQNGPKIAVQFGPG---FSWIANFTKAASTYSIDSVSFSYNTGDNTTFPD
       :: ...  ..    :   :  ::.   .:   ..:  : : . .: . :..:: ::: :.
XP_006 VTTQATPNNSHTAPPVTEVTVGPSLAPYSLPPTITPPAHTTGTSSSTVSHTTG-NTTQPS
               90       100       110       120       130          

      130       140       150       160       170       180        
pF1KB9 AEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFL
        .     :.   :.:              .:.:. . :.     ::     ::... .  
XP_006 NQT----TLPATLSI--------------ALHKSTTGQKP----VQPTHAPGTTAAAH--
     140           150                     160           170       

      190       200       210       220       230       240        
pF1KB9 CDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDKV
          . : :.::.  .:::.:: .: :. . ..: :.: ::.  :. : ::.:: :.::: 
XP_006 ---NTTRTAAPA--STVPGPTLAPQPS-SVKTGIYQVLNGSRLCIKAEMGIQL-IVQDKE
            180         190        200       210       220         

           250       260       270       280       290       300   
pF1KB9 A-----SVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVNISM
       .       .::.::.:...:.: .. . : :: .   .....:. :.:. .:..::.  .
XP_006 SVFSPRRYFNIDPNATQASGNCGTRKSNLLLNFQG-GFVNLTFT-KDEESYYISEVGAYL
      230       240       250       260        270        280      

            310       320       330       340       350       360  
pF1KB9 YLVNG-SVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQGKY
        . .  ....  .. . .... .: :. : .::....:. .:..: :...: :.  . ..
XP_006 TVSDPETIYQGIKHAVVMFQTAVGHSFKCVSEQSLQLSAHLQVKTTDVQLQAFDFEDDHF
        290       300       310       320       330       340      

            370       380       390       400       410 
pF1KB9 STAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
       ..:.:: .: .    ::::.:...  :..... . ...:..   ::.  
XP_006 GNADECFSDRN-RREIPVAMGLSITGLLVILLTACLVARKRPSRGYERM
        350        360       370       380       390    

>>XP_005247417 (OMIM: 605883) PREDICTED: lysosome-associ  (418 aa)
 initn: 266 init1:  81 opt: 382  Z-score: 463.8  bits: 94.8 E(85289): 4.3e-19
Smith-Waterman score: 395; 27.3% identity (60.5% similar) in 377 aa overlap (46-409:75-416)

          20        30        40        50          60          70 
pF1KB9 LVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNK--TYKTVTISD--HGT
                                     .:   ::.  ::.   : .:.: :   .  
XP_005 VQDIKKPVQQPAKQAPHQTLAARFMDGHITFQTAATVKIPTTTPATTKNTATTSPITYTL
           50        60        70        80        90       100    

              80        90          100       110       120        
pF1KB9 VTYNGSICGDDQNGPKIAVQFGPG---FSWIANFTKAASTYSIDSVSFSYNTGDNTTFPD
       :: ...  ..    :   :  ::.   .:   ..:  : : . .: . :..:: ::: :.
XP_005 VTTQATPNNSHTAPPVTEVTVGPSLAPYSLPPTITPPAHTTGTSSSTVSHTTG-NTTQPS
          110       120       130       140       150        160   

      130       140       150       160       170       180        
pF1KB9 AEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFL
        .     :.   :.:              .:.:. . :.     ::     ::... .  
XP_005 NQT----TLPATLSI--------------ALHKSTTGQKP----VQPTHAPGTTAAAH--
               170                     180           190           

      190       200       210       220       230       240        
pF1KB9 CDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDKV
          . : :.::.  .:::.:: .: :. . ..: :.: ::.  :. : ::.:: :.::: 
XP_005 ---NTTRTAAPA--STVPGPTLAPQPS-SVKTGIYQVLNGSRLCIKAEMGIQL-IVQDKE
        200         210       220        230       240        250  

           250       260       270       280       290       300   
pF1KB9 A-----SVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVNISM
       .       .::.::.:...:.: .. . : :: .   .....:. :.:. .:..::.  .
XP_005 SVFSPRRYFNIDPNATQASGNCGTRKSNLLLNFQG-GFVNLTFT-KDEESYYISEVGAYL
            260       270       280        290        300       310

            310       320       330       340       350       360  
pF1KB9 YLVNG-SVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQGKY
        . .  ....  .. . .... .: :. : .::....:. .:..: :...: :.  . ..
XP_005 TVSDPETIYQGIKHAVVMFQTAVGHSFKCVSEQSLQLSAHLQVKTTDVQLQAFDFEDDHF
              320       330       340       350       360       370

            370       380       390       400       410 
pF1KB9 STAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
       ..:.:: .: .    ::::.:...  :..... . ...:..   ::.  
XP_005 GNADECFSDRN-RREIPVAMGLSITGLLVILLTACLVARKRPSRGYERM
              380        390       400       410        

>>NP_055213 (OMIM: 605883) lysosome-associated membrane   (416 aa)
 initn: 199 init1:  76 opt: 361  Z-score: 438.4  bits: 90.1 E(85289): 1.1e-17
Smith-Waterman score: 374; 28.0% identity (60.4% similar) in 379 aa overlap (46-411:75-416)

          20        30        40        50          60          70 
pF1KB9 LVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNK--TYKTVTISD--HGT
                                     .:   ::.  ::.   : .:.: :   .  
NP_055 VQDIKKPVQQPAKQAPHQTLAARFMDGHITFQTAATVKIPTTTPATTKNTATTSPITYTL
           50        60        70        80        90       100    

              80        90          100       110       120        
pF1KB9 VTYNGSICGDDQNGPKIAVQFGPG---FSWIANFTKAASTYSIDSVSFSYNTGDNTTFPD
       :: ...  ..    :   :  ::.   .:   ..:  : : . .: . :..:: ::: :.
NP_055 VTTQATPNNSHTAPPVTEVTVGPSLAPYSLPPTITPPAHTTGTSSSTVSHTTG-NTTQPS
          110       120       130       140       150        160   

      130       140       150       160       170       180        
pF1KB9 AEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFL
        .     :.   :.:              .:.:. . :.     ::     ::... .  
NP_055 NQT----TLPATLSI--------------ALHKSTTGQKP----VQPTHAPGTTAAAH--
               170                     180           190           

      190       200       210       220       230       240        
pF1KB9 CDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDK-
          . : :.::.  .:::.:: .: :. . ..: :.: ::.  :. : ::.:: :.::: 
NP_055 ---NTTRTAAPA--STVPGPTLAPQPS-SVKTGIYQVLNGSRLCIKAEMGIQL-IVQDKE
        200         210       220        230       240        250  

        250          260       270       280       290       300   
pF1KB9 -VAS---VININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVNISM
        : :    .::.::.:...:.: .. . : :: .   .....:. :.:. .:..::.  .
NP_055 SVFSPRRYFNIDPNATQASGNCGTRKSNLLLNFQG-GFVNLTFT-KDEESYYISEVGAYL
            260       270       280        290        300       310

            310       320       330       340       350       360  
pF1KB9 YLVNG-SVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQGKY
        . .  ....  .. . .... .: :. : .::....:. .:..: :...: :.  . ..
NP_055 TVSDPETIYQGIKHAVVMFQTAVGHSFKCVSEQSLQLSAHLQVKTTDVQLQAFDFEDDHF
              320       330       340       350       360       370

            370       380       390       400       410 
pF1KB9 STAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV
       ....:::  :: ....::  ....:. .. . . : :  : . .::: .
NP_055 GNVDECS--SDYTIVLPVIGAIVVGLCLMGMGV-YKIRLRCQSSGYQRI
                380       390       400        410      

>>NP_001242 (OMIM: 153634) macrosialin isoform A precurs  (354 aa)
 initn: 218 init1:  68 opt: 240  Z-score: 293.1  bits: 63.0 E(85289): 1.4e-09
Smith-Waterman score: 286; 24.4% identity (55.1% similar) in 356 aa overlap (70-411:13-354)

      40        50        60        70        80        90         
pF1KB9 TCLYAKWQMNFTVRYETTNKTYKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWI
                                     : .. .:.  :.:    : :. . :.:.  
NP_001                   MRLAVLFSGALLGLLAAQGT--GNDCPHKKSATLL-PSFTVT
                                 10        20          30          

     100       110       120       130       140       150         
pF1KB9 ANFTKAASTYSIDSVSFSYNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFR--CNSLS
        . :....: :  ...   .:   ::   . ..:  :. .  .     :   .   :: .
NP_001 PTVTESTGTTSHRTTKSHKTTTHRTTTTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTA
      40        50        60        70        80        90         

       160       170       180       190       200       210       
pF1KB9 TLEKNDVVQHYWDVLVQAFVQNGTVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEK
       : .  ... :       : ...:.....    .   .   . . :   : :. .:.:  :
NP_001 TSQGPSTATHS-----PATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSK
     100       110            120       130       140       150    

       220       230       240            250       260        270 
pF1KB9 PEAGTYSVNNGNDTCLLATMGLQLNI---TQD--KVASVININPNTTHSTGSCR-SHTAL
          : :. .::.. :.     .:. .   ::   .. ..  .::: :.  :::. .:  :
NP_001 ETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHL
          160       170       180       190       200       210    

             280       290            300       310       320      
pF1KB9 LRLNSSTIKYLDFVFAVKNENRF-YLK----EVNISMYLVNGSVFSIANNNLSYWDAPLG
       :   :    .:.: :    ...  ::.    : :.:.  .   .::  : .:   .::::
NP_001 LL--SFPYGHLSFGFMQDLQQKVVYLSYMAVEYNVSFPHAAQWTFSAQNASLRDLQAPLG
            220       230       240       250       260       270  

        330       340       350        360       370       380     
pF1KB9 SSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQ-GKYSTAEECSADSDLNFLIPVAVGVA
       .:. :.. ... .: : ... ..::.:  .. . : .. .  :   :: ..:.:. .:. 
NP_001 QSFSCSN-SSIILSPAVHLDLLSLRLQAAQLPHTGVFGQSFSC--PSDRSILLPLIIGLI
             280       290       300       310         320         

         390       400       410 
pF1KB9 LGFLIIVVFISYMIGRRKSRTGYQSV
       :  :. .:.:.. : ::.  ..::..
NP_001 LLGLLALVLIAFCIIRRRP-SAYQAL
     330       340        350    

>>NP_001035148 (OMIM: 153634) macrosialin isoform B prec  (327 aa)
 initn: 194 init1:  68 opt: 238  Z-score: 291.2  bits: 62.5 E(85289): 1.8e-09
Smith-Waterman score: 281; 28.6% identity (58.9% similar) in 224 aa overlap (200-411:110-327)

     170       180       190       200       210       220         
pF1KB9 DVLVQAFVQNGTVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGN
                                     . :   : :. .:.:  :   : :. .::.
NP_001 ATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGS
      80        90       100       110       120       130         

     230       240            250       260        270       280   
pF1KB9 DTCLLATMGLQLNI---TQD--KVASVININPNTTHSTGSCR-SHTALLRLNSSTIKYLD
       . :.     .:. .   ::   .. ..  .::: :.  :::. .:  ::   :    .:.
NP_001 QPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLL--SFPYGHLS
     140       150       160       170       180         190       

           290            300       310       320       330        
pF1KB9 FVFAVKNENRF-YLK----EVNISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVS
       : :    ...  ::.    : :.:.  .   .::  : .:   .::::.:. :.. ... 
NP_001 FGFMQDLQQKVVYLSYMAVEYNVSFPHAAQWTFSAQNASLRDLQAPLGQSFSCSN-SSII
       200       210       220       230       240       250       

      340       350        360       370       380       390       
pF1KB9 VSGAFQINTFDLRVQPFNVTQ-GKYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISY
       .: : ... ..::.:  .. . : .. .  :   :: ..:.:. .:. :  :. .:.:..
NP_001 LSPAVHLDLLSLRLQAAQLPHTGVFGQSFSCP--SDRSILLPLIIGLILLGLLALVLIAF
        260       270       280         290       300       310    

       400       410 
pF1KB9 MIGRRKSRTGYQSV
        : ::.  ..::..
NP_001 CIIRRRP-SAYQAL
          320        




411 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:17:44 2016 done: Sat Nov  5 13:17:46 2016
 Total Scan time:  8.000 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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