Result of FASTA (omim) for pF1KE0549
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0549, 154 aa
  1>>>pF1KE0549 154 - 154 aa - 154 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7039+/-0.000278; mu= 15.9445+/- 0.017
 mean_var=67.2768+/-13.259, 0's: 0 Z-trim(119.1): 124  B-trim: 0 in 0/57
 Lambda= 0.156366
 statistics sampled from 32614 (32744) to 32614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.384), width:  16
 Scan time:  5.290

The best scores are:                                      opt bits E(85289)
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 1056 246.0 1.8e-65
NP_001243284 (OMIM: 603721) ubiquitin-conjugating  ( 212) 1006 234.9 5.5e-62
NP_001243285 (OMIM: 603721) ubiquitin-conjugating  ( 122)  787 185.3 2.7e-47
XP_016884424 (OMIM: 603721) PREDICTED: ubiquitin-c ( 121)  714 168.8 2.5e-42
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153)  594 141.8 4.1e-34
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147)  404 98.9 3.2e-21
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147)  399 97.8   7e-21
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148)  393 96.4 1.8e-20
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147)  391 96.0 2.4e-20
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173)  389 95.6 3.8e-20
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118)  387 95.0 3.9e-20
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149)  387 95.1 4.6e-20
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118)  381 93.7   1e-19
NP_001287724 (OMIM: 602963) ubiquitin-conjugating  ( 118)  381 93.7   1e-19
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110)  369 90.9 6.2e-19
NP_001191809 (OMIM: 602961) ubiquitin-conjugating  ( 109)  368 90.7 7.2e-19
NP_937826 (OMIM: 603890) ubiquitin/ISG15-conjugati (  87)  348 86.1 1.4e-17
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197)  347 86.2   3e-17
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167)  346 85.9 3.1e-17
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193)  337 83.9 1.4e-16
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201)  337 83.9 1.4e-16
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201)  337 83.9 1.4e-16
NP_001265483 (OMIM: 604151) ubiquitin-conjugating  ( 207)  337 83.9 1.5e-16
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207)  337 83.9 1.5e-16
NP_001265484 (OMIM: 604151) ubiquitin-conjugating  ( 207)  337 83.9 1.5e-16
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207)  337 83.9 1.5e-16
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207)  337 83.9 1.5e-16
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152)  333 82.9 2.2e-16
NP_001189405 (OMIM: 602916) ubiquitin-conjugating  ( 160)  332 82.7 2.6e-16
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176)  330 82.3 3.9e-16
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152)  308 77.3 1.1e-14
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152)  303 76.2 2.4e-14
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200)  296 74.7 8.7e-14
NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme  ( 183)  293 74.0 1.3e-13
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119)  279 70.6 8.5e-13
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189)  279 70.8 1.2e-12
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167)  277 70.3 1.5e-12
NP_001104582 (OMIM: 602846) ubiquitin-conjugating  ( 157)  273 69.4 2.7e-12
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183)  264 67.4 1.2e-11
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158)  256 65.6 3.8e-11
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158)  256 65.6 3.8e-11
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158)  256 65.6 3.8e-11
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158)  256 65.6 3.8e-11
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158)  256 65.6 3.8e-11


>>NP_003338 (OMIM: 603721) ubiquitin-conjugating enzyme   (154 aa)
 initn: 1056 init1: 1056 opt: 1056  Z-score: 1296.6  bits: 246.0 E(85289): 1.8e-65
Smith-Waterman score: 1056; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154)

               10        20        30        40        50        60
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
               70        80        90       100       110       120

              130       140       150    
pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       ::::::::::::::::::::::::::::::::::
NP_003 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
              130       140       150    

>>NP_001243284 (OMIM: 603721) ubiquitin-conjugating enzy  (212 aa)
 initn: 1003 init1: 1003 opt: 1006  Z-score: 1233.8  bits: 234.9 E(85289): 5.5e-62
Smith-Waterman score: 1006; 94.9% identity (96.8% similar) in 156 aa overlap (1-154:57-212)

                                               10        20        
pF1KE0                               MAASRRLM--KELEEIRKCGMKNFRNIQVD
                                     .:. ::    .:::::::::::::::::::
NP_001 VLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVD
         30        40        50        60        70        80      

       30        40        50        60        70        80        
pF1KE0 EANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLP
         90       100       110       120       130       140      

       90       100       110       120       130       140        
pF1KE0 VISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG
        150       160       170       180       190       200      

      150    
pF1KE0 EKRPVD
       ::::::
NP_001 EKRPVD
        210  

>>NP_001243285 (OMIM: 603721) ubiquitin-conjugating enzy  (122 aa)
 initn: 787 init1: 787 opt: 787  Z-score: 970.0  bits: 185.3 E(85289): 2.7e-47
Smith-Waterman score: 787; 97.4% identity (99.1% similar) in 116 aa overlap (39-154:7-122)

       10        20        30        40        50        60        
pF1KE0 KELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKI
                                     .. :::::::::::::::::::::::::::
NP_001                         MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKI
                                       10        20        30      

       70        80        90       100       110       120        
pF1KE0 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE
         40        50        60        70        80        90      

      130       140       150    
pF1KE0 YSKDRKKFCKNAEEFTKKYGEKRPVD
       ::::::::::::::::::::::::::
NP_001 YSKDRKKFCKNAEEFTKKYGEKRPVD
        100       110       120  

>>XP_016884424 (OMIM: 603721) PREDICTED: ubiquitin-conju  (121 aa)
 initn: 714 init1: 714 opt: 714  Z-score: 881.0  bits: 168.8 E(85289): 2.5e-42
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 103 aa overlap (1-103:1-103)

               10        20        30        40        50        60
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_016 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQETSAFPIMASLRSSLEV
               70        80        90       100       110       120

              130       140       150    
pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
                                         
XP_016 L                                 
                                         

>>NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugating e  (153 aa)
 initn: 594 init1: 594 opt: 594  Z-score: 733.4  bits: 141.8 E(85289): 4.1e-34
Smith-Waterman score: 594; 55.3% identity (80.3% similar) in 152 aa overlap (1-152:1-152)

               10        20        30        40        50        60
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
       : :: :..::::...:     .::.. :.::.:.:..:..::.:::   :: ..:.:: :
NP_004 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
       :::::: : : :::::::.::.::.:::.::.::::: ::: ::...: .::: :. ..:
NP_004 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP
               70        80        90       100       110       120

              130       140       150    
pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       :: :::.  ... . : ::::::: ..:  ::  
NP_004 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS 
              130       140       150    

>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme   (147 aa)
 initn: 358 init1: 184 opt: 404  Z-score: 502.0  bits: 98.9 E(85289): 3.2e-21
Smith-Waterman score: 404; 39.0% identity (74.7% similar) in 146 aa overlap (3-147:2-145)

               10        20        30        40         50         
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
         : .:..::: ....    .     : . .:. ::. :. : .  :. :.: . ..::.
NP_003  MALKRIQKELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPT
                10        20         30        40        50        

      60        70        80        90       100       110         
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
       .::::::::.: ::::::::. .:..:: .. .. :.::  ...:. :. .:. ::.:. 
NP_003 DYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQ-WSPALTVSKVLLSICSLLCDPNPDD
       60        70        80        90        100       110       

     120       130       140       150    
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       ::  :.:. :..:..:. ..:.:.:.::       
NP_003 PLVPDIAQIYKSDKEKYNRHAREWTQKYAM     
       120       130       140            

>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme   (147 aa)
 initn: 385 init1: 229 opt: 399  Z-score: 495.9  bits: 97.8 E(85289): 7e-21
Smith-Waterman score: 399; 38.4% identity (73.3% similar) in 146 aa overlap (3-147:2-145)

               10        20        30        40         50         
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
         : .:. :::... .    .     : . ... ::. :. :.. ::. :.: . :.::.
NP_003  MALKRIHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
                10        20         30        40        50        

      60        70        80        90       100       110         
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
       .:::::::..: :.::::::. .:..:: .. .. :.::   ..:. :. .:. ::.:. 
NP_003 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
       60        70        80        90        100       110       

     120       130       140       150    
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       ::  ..:. :. ::.:. . :.:.:.::       
NP_003 PLVPEIARIYKTDREKYNRIAREWTQKYAM     
       120       130       140            

>>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme   (148 aa)
 initn: 381 init1: 229 opt: 393  Z-score: 488.5  bits: 96.4 E(85289): 1.8e-20
Smith-Waterman score: 393; 38.4% identity (71.9% similar) in 146 aa overlap (3-147:2-145)

               10        20        30        40         50         
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
         : .:. ::: .. .    .     : . ... ::. :. :.. ::. :.: . :.::.
NP_871  MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
                10        20         30        40        50        

      60        70        80        90       100       110         
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
       .:::::::..: :.::::::. .:..:: .. .. :.::   ..:. :. .:. ::.:. 
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
       60        70        80        90        100       110       

     120       130       140       150    
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       ::  ..:. :. :: :. . :.:.:.::       
NP_871 PLVPEIARIYKTDRDKYNRLAREWTEKYAML    
       120       130       140            

>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme   (147 aa)
 initn: 379 init1: 229 opt: 391  Z-score: 486.1  bits: 96.0 E(85289): 2.4e-20
Smith-Waterman score: 391; 37.7% identity (71.9% similar) in 146 aa overlap (3-147:2-145)

               10        20        30        40         50         
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
         : .:. ::: .. .    .     : . ... ::. :. :.. ::. :.: . :.::.
NP_871  MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
                10        20         30        40        50        

      60        70        80        90       100       110         
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
       .:::::::..: :.::::::. .:..:: .. .. :.::   ..:. :. .:. ::.:. 
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
       60        70        80        90        100       110       

     120       130       140       150    
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       ::  ..:. :. :: :. . ..:.:.::       
NP_871 PLVPEIARIYKTDRDKYNRISREWTQKYAM     
       120       130       140            

>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme   (147 aa)
 initn: 379 init1: 229 opt: 391  Z-score: 486.1  bits: 96.0 E(85289): 2.4e-20
Smith-Waterman score: 391; 37.7% identity (71.9% similar) in 146 aa overlap (3-147:2-145)

               10        20        30        40         50         
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
         : .:. ::: .. .    .     : . ... ::. :. :.. ::. :.: . :.::.
NP_871  MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
                10        20         30        40        50        

      60        70        80        90       100       110         
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
       .:::::::..: :.::::::. .:..:: .. .. :.::   ..:. :. .:. ::.:. 
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
       60        70        80        90        100       110       

     120       130       140       150    
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
       ::  ..:. :. :: :. . ..:.:.::       
NP_871 PLVPEIARIYKTDRDKYNRISREWTQKYAM     
       120       130       140            




154 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:56:09 2016 done: Wed Nov  2 23:56:10 2016
 Total Scan time:  5.290 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com