Result of FASTA (omim) for pF1KB5459
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5459, 391 aa
  1>>>pF1KB5459 391 - 391 aa - 391 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2512+/-0.000352; mu= 12.3079+/- 0.022
 mean_var=88.3105+/-18.364, 0's: 0 Z-trim(115.3): 11  B-trim: 883 in 1/55
 Lambda= 0.136480
 statistics sampled from 25616 (25625) to 25616 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.3), width:  16
 Scan time:  8.880

The best scores are:                                      opt bits E(85289)
NP_006463 (OMIM: 606599) thioredoxin-interacting p ( 391) 2628 527.5 2.1e-149
XP_016855574 (OMIM: 606599) PREDICTED: thioredoxin ( 395) 2554 512.9 5.3e-145
NP_001300901 (OMIM: 606599) thioredoxin-interactin ( 336) 2097 422.9 5.6e-118
NP_065852 (OMIM: 612464) arrestin domain-containin ( 414)  946 196.3 1.1e-49
NP_001316599 (OMIM: 612464) arrestin domain-contai ( 194)  550 118.2 1.7e-26
NP_001316601 (OMIM: 612464) arrestin domain-contai ( 194)  550 118.2 1.7e-26
NP_001316600 (OMIM: 612464) arrestin domain-contai ( 194)  550 118.2 1.7e-26


>>NP_006463 (OMIM: 606599) thioredoxin-interacting prote  (391 aa)
 initn: 2628 init1: 2628 opt: 2628  Z-score: 2803.1  bits: 527.5 E(85289): 2.1e-149
Smith-Waterman score: 2628; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391)

               10        20        30        40        50        60
pF1KB5 MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
              310       320       330       340       350       360

              370       380       390 
pF1KB5 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
       :::::::::::::::::::::::::::::::
NP_006 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
              370       380       390 

>>XP_016855574 (OMIM: 606599) PREDICTED: thioredoxin-int  (395 aa)
 initn: 2554 init1: 2554 opt: 2554  Z-score: 2724.3  bits: 512.9 E(85289): 5.3e-145
Smith-Waterman score: 2554; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)

               10        20        30        40        50        60
pF1KB5 MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
              310       320       330       340       350       360

              370       380       390     
pF1KB5 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ    
       :::::::::::::::::::::              
XP_016 SPIFMYAPEFKFMPPPTYTEVRIVIFTVKFVLSFL
              370       380       390     

>>NP_001300901 (OMIM: 606599) thioredoxin-interacting pr  (336 aa)
 initn: 2097 init1: 2097 opt: 2097  Z-score: 2239.1  bits: 422.9 E(85289): 5.6e-118
Smith-Waterman score: 2097; 99.7% identity (100.0% similar) in 310 aa overlap (82-391:27-336)

              60        70        80        90       100       110 
pF1KB5 AKVLWMQGSQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLG
                                     :.::::::::::::::::::::::::::::
NP_001     MPPKHSLSHRCILSVTASLMATRFSFPSGENEMVIMRPGNKYEYKFGFELPQGPLG
                   10        20        30        40        50      

             120       130       140       150       160       170 
pF1KB5 TSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCM
         60        70        80        90       100       110      

             180       190       200       210       220       230 
pF1KB5 FIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLT
        120       130       140       150       160       170      

             240       250       260       270       280       290 
pF1KB5 QKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILD
        180       190       200       210       220       230      

             300       310       320       330       340       350 
pF1KB5 LPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPL
        240       250       260       270       280       290      

             360       370       380       390 
pF1KB5 LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
       ::::::::::::::::::::::::::::::::::::::::
NP_001 LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
        300       310       320       330      

>>NP_065852 (OMIM: 612464) arrestin domain-containing pr  (414 aa)
 initn: 1038 init1: 672 opt: 946  Z-score: 1012.9  bits: 196.3 E(85289): 1.1e-49
Smith-Waterman score: 1049; 42.1% identity (70.8% similar) in 401 aa overlap (2-383:1-399)

               10            20        30        40        50      
pF1KB5 MVMFKKIKSFEVVF---NDPE-KVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLW
        ... :.::. . :   :: .  ::.::. :.::: .::    :::...: : : ::: :
NP_065  MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRW
                10        20        30        40        50         

             60             70          80        90       100     
pF1KB5 MQ----GS-----QQCKQTSEYLRYEDTLL--LEDQPTGENEMVIMRPGNKYEYKFGFEL
        .    ::     :.  .  ::. ..: :.   .:. ..:. .  .. : ..:: :.:::
NP_065 TESRNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNSEEGFHTIHSG-RHEYAFSFEL
      60        70        80        90       100        110        

         110       120       130       140       150       160     
pF1KB5 PQGPLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKE
       :: ::.:::.:..: : ::::: : ::     . ::.: : . .:.:::.:..: .. ::
NP_065 PQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKE
      120       130       140       150       160       170        

         170       180       190       200       210       220     
pF1KB5 KKVSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANG
       : . : :  .: .:.::.:.:::.  :. :.: :..::  ::.:::::::   ... :.:
NP_065 KTLCCWFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKG
      180       190       200       210       220       230        

         230       240       250       260       270       280     
pF1KB5 QTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGS
       . : . : ....::. . ::   .: :: :..  . :::: :.:.::::::..::..::.
NP_065 KMKEVKQLVANLRGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGA
      240       250       260       270       280       290        

         290         300       310       320       330       340   
pF1KB5 KKVILDLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHR
         ..:.::::::.     ..:::::..:. : .:.:..:..:. ::::: : .:. :..:
NP_065 MDLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQR
      300       310       320       330       340       350        

           350         360       370       380       390        
pF1KB5 LESPTTPL--LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ       
        ..  .:.   ::.. . ..:.: :  ::.:.::: :.:.::               
NP_065 -RNNLAPVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSCPSR
       360       370       380       390       400       410    

>>NP_001316599 (OMIM: 612464) arrestin domain-containing  (194 aa)
 initn: 559 init1: 299 opt: 550  Z-score: 596.5  bits: 118.2 E(85289): 1.7e-26
Smith-Waterman score: 550; 43.3% identity (75.6% similar) in 180 aa overlap (208-383:1-179)

       180       190       200       210       220       230       
pF1KB5 VSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSV
                                     .:::::::   ... :.:. : . : ....
NP_001                               MVVPKAAIYQTQAFYAKGKMKEVKQLVANL
                                             10        20        30

       240       250       260       270       280       290       
pF1KB5 RGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIG
       ::. . ::   .: :: :..  . :::: :.:.::::::..::..::.  ..:.::::::
NP_001 RGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLFLNLPLVIG
               40        50        60        70        80        90

         300       310       320       330       340         350   
pF1KB5 S--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLES--PTTPLLD
       .     ..:::::..:. : .:.:..:..:. ::::: : .:. :..: ..  :..   :
NP_001 TIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQRRNNLAPVSAC-D
              100       110       120       130       140          

           360       370       380       390        
pF1KB5 DMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ       
       :.. . ..:.: :  ::.:.::: :.:.::               
NP_001 DFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSCPSR
     150       160       170       180       190    

>>NP_001316601 (OMIM: 612464) arrestin domain-containing  (194 aa)
 initn: 559 init1: 299 opt: 550  Z-score: 596.5  bits: 118.2 E(85289): 1.7e-26
Smith-Waterman score: 550; 43.3% identity (75.6% similar) in 180 aa overlap (208-383:1-179)

       180       190       200       210       220       230       
pF1KB5 VSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSV
                                     .:::::::   ... :.:. : . : ....
NP_001                               MVVPKAAIYQTQAFYAKGKMKEVKQLVANL
                                             10        20        30

       240       250       260       270       280       290       
pF1KB5 RGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIG
       ::. . ::   .: :: :..  . :::: :.:.::::::..::..::.  ..:.::::::
NP_001 RGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLFLNLPLVIG
               40        50        60        70        80        90

         300       310       320       330       340         350   
pF1KB5 S--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLES--PTTPLLD
       .     ..:::::..:. : .:.:..:..:. ::::: : .:. :..: ..  :..   :
NP_001 TIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQRRNNLAPVSAC-D
              100       110       120       130       140          

           360       370       380       390        
pF1KB5 DMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ       
       :.. . ..:.: :  ::.:.::: :.:.::               
NP_001 DFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSCPSR
     150       160       170       180       190    

>>NP_001316600 (OMIM: 612464) arrestin domain-containing  (194 aa)
 initn: 559 init1: 299 opt: 550  Z-score: 596.5  bits: 118.2 E(85289): 1.7e-26
Smith-Waterman score: 550; 43.3% identity (75.6% similar) in 180 aa overlap (208-383:1-179)

       180       190       200       210       220       230       
pF1KB5 VSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSV
                                     .:::::::   ... :.:. : . : ....
NP_001                               MVVPKAAIYQTQAFYAKGKMKEVKQLVANL
                                             10        20        30

       240       250       260       270       280       290       
pF1KB5 RGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIG
       ::. . ::   .: :: :..  . :::: :.:.::::::..::..::.  ..:.::::::
NP_001 RGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLFLNLPLVIG
               40        50        60        70        80        90

         300       310       320       330       340         350   
pF1KB5 S--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLES--PTTPLLD
       .     ..:::::..:. : .:.:..:..:. ::::: : .:. :..: ..  :..   :
NP_001 TIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQRRNNLAPVSAC-D
              100       110       120       130       140          

           360       370       380       390        
pF1KB5 DMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ       
       :.. . ..:.: :  ::.:.::: :.:.::               
NP_001 DFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSCPSR
     150       160       170       180       190    




391 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 21:40:12 2016 done: Fri Nov  4 21:40:13 2016
 Total Scan time:  8.880 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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