Result of FASTA (omim) for pF1KB7214
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7214, 293 aa
  1>>>pF1KB7214 293 - 293 aa - 293 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0190+/-0.000294; mu= 8.4634+/- 0.018
 mean_var=115.3393+/-22.637, 0's: 0 Z-trim(120.9): 311  B-trim: 0 in 0/54
 Lambda= 0.119422
 statistics sampled from 36515 (36835) to 36515 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.432), width:  16
 Scan time:  7.700

The best scores are:                                      opt bits E(85289)
NP_659205 (OMIM: 608159) testisin isoform 2 prepro ( 312)  628 118.3 1.9e-26
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343)  607 114.7 2.5e-25
NP_114154 (OMIM: 608018) serine protease 27 isofor ( 290)  600 113.5   5e-25
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436)  596 112.9 1.1e-24
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436)  596 112.9 1.1e-24
NP_000883 (OMIM: 229000,612423) plasma kallikrein  ( 638)  596 113.0 1.6e-24
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649)  596 113.0 1.6e-24
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649)  596 113.0 1.6e-24
NP_690851 (OMIM: 613797) serine protease 33 precur ( 280)  577 109.5 7.6e-24
XP_011520754 (OMIM: 613797) PREDICTED: serine prot ( 280)  577 109.5 7.6e-24
XP_011520753 (OMIM: 613797) PREDICTED: serine prot ( 280)  577 109.5 7.6e-24
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802)  566 107.9 6.8e-23
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811)  566 107.9 6.9e-23
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321)  558 106.3 8.2e-23
XP_016878364 (OMIM: 608159) PREDICTED: testisin is ( 298)  555 105.7 1.1e-22
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275)  549 104.7 2.1e-22
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536)  553 105.5 2.3e-22
XP_006714200 (OMIM: 264900,612416) PREDICTED: coag ( 610)  553 105.6 2.6e-22
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346)  549 104.7 2.6e-22
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346)  549 104.7 2.6e-22
NP_000119 (OMIM: 264900,612416) coagulation factor ( 625)  553 105.6 2.6e-22
XP_005262878 (OMIM: 264900,612416) PREDICTED: coag ( 626)  553 105.6 2.6e-22
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275)  546 104.2   3e-22
NP_940866 (OMIM: 615144) serine protease 55 isofor ( 352)  543 103.7 5.3e-22
NP_001275679 (OMIM: 606751) transmembrane protease ( 413)  543 103.7 6.1e-22
NP_001275680 (OMIM: 606751) transmembrane protease ( 448)  543 103.8 6.5e-22
NP_110397 (OMIM: 606751) transmembrane protease se ( 457)  543 103.8 6.6e-22
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384)  536 102.5 1.3e-21
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452)  536 102.6 1.5e-21
NP_005647 (OMIM: 602060) transmembrane protease se ( 492)  536 102.6 1.6e-21
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492)  536 102.6 1.6e-21
NP_001128571 (OMIM: 602060) transmembrane protease ( 529)  536 102.6 1.7e-21
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317)  525 100.6 4.2e-21
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317)  525 100.6 4.2e-21
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264)  522 100.0 5.1e-21
NP_001277025 (OMIM: 606565) transmembrane protease ( 290)  518 99.4   9e-21
NP_001193718 (OMIM: 610050) transmembrane protease ( 532)  521 100.0   1e-20
NP_001231924 (OMIM: 610050) transmembrane protease ( 563)  521 100.0 1.1e-20
NP_001070731 (OMIM: 610050) transmembrane protease ( 567)  521 100.0 1.1e-20
NP_001167023 (OMIM: 606565) transmembrane protease ( 397)  518 99.4 1.2e-20
NP_001277023 (OMIM: 606565) transmembrane protease ( 412)  518 99.4 1.2e-20
NP_001077416 (OMIM: 606565) transmembrane protease ( 432)  518 99.4 1.3e-20
NP_001167022 (OMIM: 606565) transmembrane protease ( 435)  518 99.4 1.3e-20
NP_063947 (OMIM: 606565) transmembrane protease se ( 437)  518 99.4 1.3e-20
NP_115780 (OMIM: 605511) transmembrane protease se ( 327)  509 97.8 2.9e-20
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263)  507 97.4 3.1e-20
NP_076927 (OMIM: 605511) transmembrane protease se ( 454)  509 97.9 3.8e-20
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454)  506 97.4 5.5e-20
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456)  506 97.4 5.5e-20
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489)  506 97.4 5.8e-20


>>NP_659205 (OMIM: 608159) testisin isoform 2 preproprot  (312 aa)
 initn: 576 init1: 387 opt: 628  Z-score: 595.9  bits: 118.3 E(85289): 1.9e-26
Smith-Waterman score: 643; 41.4% identity (62.3% similar) in 268 aa overlap (37-293:12-262)

         10        20        30        40        50        60      
pF1KB7 SRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSF
                                     ::.. : ..::.. : .: .::        
NP_659                    MGARGALLLALLLARAGLRKPESQEA-APLSGP--------
                                  10        20         30          

         70          80        90       100       110       120    
pF1KB7 PGDSLLCGRTPL--RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISS
             :::  .  ::::: ::: :::::: :.:    :.:: .:..  :.:::.::. .
NP_659 ------CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFET
                   40        50        60        70        80      

              130       140       150       160          170       
pF1KB7 RFH----YSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRN---DLALLQLQHPVN
        .     . :..:. . .    :. .   : ::   . .   . :   :.::..:. ::.
NP_659 DLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVT
         90       100       110       120       130       140      

       180       190       200       210        220       230      
pF1KB7 FTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLAS-EILQDVDQYIMCYEECNKII
       .:..:::::.   .:. :.:: :::::::   : : : : . ::.:.  :.    ::...
NP_659 YTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLF
        150       160       170       180       190       200      

        240       250        260       270       280       290     
pF1KB7 QKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR  
        :  :  :: :.  ::: :  . :::.: ::::: :::. :  : :.:.::::.::::  
NP_659 LK-YSFRKD-IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPN
         210        220       230       240       250       260    

NP_659 RPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPLLGPV
          270       280       290       300       310  

>>NP_002764 (OMIM: 600823) prostasin preproprotein [Homo  (343 aa)
 initn: 545 init1: 223 opt: 607  Z-score: 575.7  bits: 114.7 E(85289): 2.5e-25
Smith-Waterman score: 607; 40.8% identity (66.7% similar) in 228 aa overlap (73-292:37-263)

             50        60        70         80        90       100 
pF1KB7 GENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPL-RIVGGVDAEEGRWPWQVSVRTKG
                                     :: .:  ::.:: .:  :.::::::.  .:
NP_002 LGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG
         10        20        30        40        50        60      

             110       120          130       140       150        
pF1KB7 RHICGGTLVTATWVLTAGHCISSRFH---YSVKMGDRSVYNENTSVVVSVQRAFV-HPKF
        :.:::.::.  :::.:.::. :. :   : ::.: ... . . .. ::. . .. ::..
NP_002 VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSY
         70        80        90       100       110       120      

       160       170       180       190       200        210      
pF1KB7 STVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKT-PEREKLAS
           . ..:.:::::..:..:.  :.:::.:  : .  .  .: :::::.. :    :. 
NP_002 LQEGS-QGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTP
        130        140       150       160       170       180     

        220       230        240       250        260       270    
pF1KB7 EILQDVDQYIMCYEECNKIIQ-KALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACE
       . ::...  ..  : :: . .  :       . . ::: :: : :::.::::::: :.: 
NP_002 KPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCP
         190       200       210       220       230       240     

          280       290                                            
pF1KB7 YNDTWVQVGIVSWGIGCGR                                         
        .  :  .:::::: .::                                          
NP_002 VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNL
         250       260       270       280       290       300     

>>NP_114154 (OMIM: 608018) serine protease 27 isoform 1   (290 aa)
 initn: 544 init1: 225 opt: 600  Z-score: 570.3  bits: 113.5 E(85289): 5e-25
Smith-Waterman score: 600; 37.9% identity (66.0% similar) in 253 aa overlap (56-293:5-255)

          30        40        50        60            70           
pF1KB7 AGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFPGD----SLLCGRTPL--R
                                     :. :: :.  : ..    .  :::  .  :
NP_114                           MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNR
                                         10        20        30    

      80        90       100       110       120          130      
pF1KB7 IVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCI---SSRFHYSVKMGDRS
       .::: :..::.::::::.. .: :.:::.:..  :::::.::.   :    :.: .: :.
NP_114 MVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQ
           40        50        60        70        80        90    

        140        150       160       170       180       190     
pF1KB7 VYNENTSVVVS-VQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVE
       . . .  .. . :...  .: .. ...   :.::..:. :: ::. : :.:.:. .   :
NP_114 LVQPGPHAMYARVRQVESNPLYQGTAS-SADVALVELEAPVPFTNYILPVCLPDPSVIFE
          100       110       120        130       140       150   

         200       210         220       230         240       250 
pF1KB7 GRTRCWVTGWGKTPEREKLASE--ILQDVDQYIMCYEECNKIIQK--ALSSTKDVIIKGM
           ::::::: .: .: :  :  ::: .   :.   .:: . .:   ..    .: . :
NP_114 TGMNCWVTGWG-SPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDM
           160        170       180       190       200       210  

              260       270       280       290                    
pF1KB7 VC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR                 
       .: :..:  ::.:.::::: :.:  ...:.:.:..::: ::.:                 
NP_114 LCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI
            220       230       240       250       260       270  

NP_114 HRIIPKLQFQPARLGGQK
            280       290

>>NP_001305325 (OMIM: 229000,612423) plasma kallikrein i  (436 aa)
 initn: 497 init1: 204 opt: 596  Z-score: 563.9  bits: 112.9 E(85289): 1.1e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:149-402)

        10        20        30        40        50        60       
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
                                     :: .:. .  :  . :  .:  : : ..  
NP_001 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
      120       130       140       150       160        170       

        70         80        90       100          110       120   
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
       ::. .:  .:  :::::...  :.::::::...:    ::.:::.:.   :::::.::..
NP_001 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
         180       190       200       210       220       230     

           130           140       150       160       170         
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
       .    .:     .. :     . .   .... ..: ... :.   .:.::..:: :.:.:
NP_001 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
         240       250       260       270        280       290    

     180       190       200       210       220       230         
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
          .:::.:...      : ::::::: . :. .. ..::: :.  ..  :::    :: 
NP_001 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
          300       310       320        330       340             

     240       250        260       270       280       290        
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR     
        .. :  : . ::: :::: :::.:.::::: :.:..:  :  :::.::: ::.:     
NP_001 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
     350         360       370       380       390       400       

NP_001 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
       410       420       430      

>>XP_016863673 (OMIM: 229000,612423) PREDICTED: plasma k  (436 aa)
 initn: 497 init1: 204 opt: 596  Z-score: 563.9  bits: 112.9 E(85289): 1.1e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:149-402)

        10        20        30        40        50        60       
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
                                     :: .:. .  :  . :  .:  : : ..  
XP_016 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
      120       130       140       150       160        170       

        70         80        90       100          110       120   
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
       ::. .:  .:  :::::...  :.::::::...:    ::.:::.:.   :::::.::..
XP_016 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
         180       190       200       210       220       230     

           130           140       150       160       170         
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
       .    .:     .. :     . .   .... ..: ... :.   .:.::..:: :.:.:
XP_016 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
         240       250       260       270        280       290    

     180       190       200       210       220       230         
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
          .:::.:...      : ::::::: . :. .. ..::: :.  ..  :::    :: 
XP_016 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
          300       310       320        330       340             

     240       250        260       270       280       290        
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR     
        .. :  : . ::: :::: :::.:.::::: :.:..:  :  :::.::: ::.:     
XP_016 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
     350         360       370       380       390       400       

XP_016 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
       410       420       430      

>>NP_000883 (OMIM: 229000,612423) plasma kallikrein isof  (638 aa)
 initn: 477 init1: 204 opt: 596  Z-score: 561.4  bits: 113.0 E(85289): 1.6e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:351-604)

        10        20        30        40        50        60       
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
                                     :: .:. .  :  . :  .:  : : ..  
NP_000 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
              330       340       350       360        370         

        70         80        90       100          110       120   
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
       ::. .:  .:  :::::...  :.::::::...:    ::.:::.:.   :::::.::..
NP_000 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
       380       390       400       410       420       430       

           130           140       150       160       170         
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
       .    .:     .. :     . .   .... ..: ... :.   .:.::..:: :.:.:
NP_000 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
       440       450       460       470        480       490      

     180       190       200       210       220       230         
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
          .:::.:...      : ::::::: . :. .. ..::: :.  ..  :::    :: 
NP_000 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
        500       510       520       530        540           550 

     240       250        260       270       280       290        
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR     
        .. :  : . ::: :::: :::.:.::::: :.:..:  :  :::.::: ::.:     
NP_000 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
               560       570       580       590       600         

NP_000 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
     610       620       630        

>>XP_016863670 (OMIM: 229000,612423) PREDICTED: plasma k  (649 aa)
 initn: 477 init1: 204 opt: 596  Z-score: 561.3  bits: 113.0 E(85289): 1.6e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:362-615)

        10        20        30        40        50        60       
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
                                     :: .:. .  :  . :  .:  : : ..  
XP_016 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
             340       350       360       370        380          

        70         80        90       100          110       120   
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
       ::. .:  .:  :::::...  :.::::::...:    ::.:::.:.   :::::.::..
XP_016 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
      390       400       410       420       430       440        

           130           140       150       160       170         
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
       .    .:     .. :     . .   .... ..: ... :.   .:.::..:: :.:.:
XP_016 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
      450       460       470       480        490       500       

     180       190       200       210       220       230         
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
          .:::.:...      : ::::::: . :. .. ..::: :.  ..  :::    :: 
XP_016 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
       510       520       530       540        550           560  

     240       250        260       270       280       290        
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR     
        .. :  : . ::: :::: :::.:.::::: :.:..:  :  :::.::: ::.:     
XP_016 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
              570       580       590       600       610       620

XP_016 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
              630       640         

>>XP_011530232 (OMIM: 229000,612423) PREDICTED: plasma k  (649 aa)
 initn: 477 init1: 204 opt: 596  Z-score: 561.3  bits: 113.0 E(85289): 1.6e-24
Smith-Waterman score: 596; 38.9% identity (64.9% similar) in 265 aa overlap (38-293:362-615)

        10        20        30        40        50        60       
pF1KB7 RGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFP
                                     :: .:. .  :  . :  .:  : : ..  
XP_011 TCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGS-SGYSLRLCNT--
             340       350       360       370        380          

        70         80        90       100          110       120   
pF1KB7 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS
       ::. .:  .:  :::::...  :.::::::...:    ::.:::.:.   :::::.::..
XP_011 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD
      390       400       410       420       430       440        

           130           140       150       160       170         
pF1KB7 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT
       .    .:     .. :     . .   .... ..: ... :.   .:.::..:: :.:.:
XP_011 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT
      450       460       470       480        490       500       

     180       190       200       210       220       230         
pF1KB7 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA
          .:::.:...      : ::::::: . :. .. ..::: :.  ..  :::    :: 
XP_011 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEEC----QKR
       510       520       530       540        550           560  

     240       250        260       270       280       290        
pF1KB7 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR     
        .. :  : . ::: :::: :::.:.::::: :.:..:  :  :::.::: ::.:     
XP_011 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG
              570       580       590       600       610       620

XP_011 VYTKVAEYMDWILEKTQSSDGKAQMQSPA
              630       640         

>>NP_690851 (OMIM: 613797) serine protease 33 precursor   (280 aa)
 initn: 536 init1: 227 opt: 577  Z-score: 549.1  bits: 109.5 E(85289): 7.6e-24
Smith-Waterman score: 577; 38.4% identity (64.2% similar) in 232 aa overlap (70-291:25-255)

      40        50        60        70          80        90       
pF1KB7 EEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCG--RTPLRIVGGVDAEEGRWPWQVSV
                                     :  ::  :   ::::: :...:.::::.:.
NP_690       MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASI
                     10        20        30        40        50    

       100       110       120          130       140        150   
pF1KB7 RTKGRHICGGTLVTATWVLTAGHCISSRF---HYSVKMGDRSVYNENT-SVVVSVQRAFV
       . .: :.:::.:..  :::::.::.  :    .: :..:   . . .  .. : :.:...
NP_690 QHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLL
           60        70        80        90       100       110    

           160       170       180       190       200       210   
pF1KB7 HPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREK
        : .:     :.:::::::..:: ... .::.:.:  . .    : : :::::.      
NP_690 PPDYSE-DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVP
          120        130       140       150       160       170   

            220       230         240       250        260         
pF1KB7 LAS-EILQDVDQYIMCYEECNKI--IQKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGG
       :   . :: :   ..  . :. .  .   . ... ... : .: :: .  ::.:::::::
NP_690 LPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGG
           180       190       200       210       220       230   

     270       280       290                          
pF1KB7 RLACEYNDTWVQVGIVSWGIGCGR                       
        :.:  . .:: ::.:::: ::                         
NP_690 PLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
           240       250       260       270       280

>>XP_011520754 (OMIM: 613797) PREDICTED: serine protease  (280 aa)
 initn: 536 init1: 227 opt: 577  Z-score: 549.1  bits: 109.5 E(85289): 7.6e-24
Smith-Waterman score: 577; 38.4% identity (64.2% similar) in 232 aa overlap (70-291:25-255)

      40        50        60        70          80        90       
pF1KB7 EEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCG--RTPLRIVGGVDAEEGRWPWQVSV
                                     :  ::  :   ::::: :...:.::::.:.
XP_011       MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASI
                     10        20        30        40        50    

       100       110       120          130       140        150   
pF1KB7 RTKGRHICGGTLVTATWVLTAGHCISSRF---HYSVKMGDRSVYNENT-SVVVSVQRAFV
       . .: :.:::.:..  :::::.::.  :    .: :..:   . . .  .. : :.:...
XP_011 QHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLL
           60        70        80        90       100       110    

           160       170       180       190       200       210   
pF1KB7 HPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREK
        : .:     :.:::::::..:: ... .::.:.:  . .    : : :::::.      
XP_011 PPDYSE-DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVP
          120        130       140       150       160       170   

            220       230         240       250        260         
pF1KB7 LAS-EILQDVDQYIMCYEECNKI--IQKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGG
       :   . :: :   ..  . :. .  .   . ... ... : .: :: .  ::.:::::::
XP_011 LPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGG
           180       190       200       210       220       230   

     270       280       290                          
pF1KB7 RLACEYNDTWVQVGIVSWGIGCGR                       
        :.:  . .:: ::.:::: ::                         
XP_011 PLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
           240       250       260       270       280




293 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 21:00:07 2016 done: Sat Nov  5 21:00:08 2016
 Total Scan time:  7.700 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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