Result of FASTA (omim) for pF1KE0450
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0450, 448 aa
  1>>>pF1KE0450 448 - 448 aa - 448 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2058+/-0.000368; mu= 19.2406+/- 0.023
 mean_var=85.5188+/-18.204, 0's: 0 Z-trim(114.4): 22  B-trim: 1175 in 1/50
 Lambda= 0.138689
 statistics sampled from 24285 (24303) to 24285 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.285), width:  16
 Scan time:  9.470

The best scores are:                                      opt bits E(85289)
NP_001135863 (OMIM: 312090) P3 protein isoform 2 p ( 448) 2871 584.5 1.9e-166
XP_006724911 (OMIM: 312090) PREDICTED: P3 protein  ( 541) 2871 584.6 2.2e-166
XP_011529503 (OMIM: 312090) PREDICTED: P3 protein  ( 477) 2083 426.9 5.8e-119
NP_001135864 (OMIM: 312090) P3 protein isoform 1 p ( 477) 2083 426.9 5.8e-119
NP_062822 (OMIM: 312090) P3 protein isoform 1 prec ( 477) 2083 426.9 5.8e-119
XP_005277970 (OMIM: 312090) PREDICTED: P3 protein  ( 532) 2083 426.9 6.3e-119
XP_011529502 (OMIM: 312090) PREDICTED: P3 protein  ( 532) 2083 426.9 6.3e-119
XP_006724910 (OMIM: 312090) PREDICTED: P3 protein  ( 570) 2083 426.9 6.6e-119
NP_932069 (OMIM: 613366) solute carrier family 10  ( 377)  452 100.4 8.5e-21
NP_003040 (OMIM: 182396) sodium/bile acid cotransp ( 349)  438 97.6 5.6e-20
NP_000443 (OMIM: 601295,613291) ileal sodium/bile  ( 348)  434 96.8 9.7e-20


>>NP_001135863 (OMIM: 312090) P3 protein isoform 2 precu  (448 aa)
 initn: 2871 init1: 2871 opt: 2871  Z-score: 3109.2  bits: 584.5 E(85289): 1.9e-166
Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)

               10        20        30        40        50        60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 KVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 IAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 ITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAP
              370       380       390       400       410       420

              430       440        
pF1KE0 FIVALSGTSEMLALVIGHFIYSSLFPVP
       ::::::::::::::::::::::::::::
NP_001 FIVALSGTSEMLALVIGHFIYSSLFPVP
              430       440        

>>XP_006724911 (OMIM: 312090) PREDICTED: P3 protein isof  (541 aa)
 initn: 2871 init1: 2871 opt: 2871  Z-score: 3108.1  bits: 584.6 E(85289): 2.2e-166
Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:94-541)

                                             10        20        30
pF1KE0                               MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
                                     ::::::::::::::::::::::::::::::
XP_006 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
            70        80        90       100       110       120   

               40        50        60        70        80        90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
           130       140       150       160       170       180   

              100       110       120       130       140       150
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QYPGQANRTAPGPMLRVTSLDTEVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPAT
           190       200       210       220       230       240   

              160       170       180       190       200       210
pF1KE0 LSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPL
           250       260       270       280       290       300   

              220       230       240       250       260       270
pF1KE0 YAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFL
           310       320       330       340       350       360   

              280       290       300       310       320       330
pF1KE0 PLSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFS
           370       380       390       400       410       420   

              340       350       360       370       380       390
pF1KE0 FVLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FVLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSI
           430       440       450       460       470       480   

              400       410       420       430       440        
pF1KE0 EVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
           490       500       510       520       530       540 

>>XP_011529503 (OMIM: 312090) PREDICTED: P3 protein isof  (477 aa)
 initn: 2083 init1: 2083 opt: 2083  Z-score: 2256.7  bits: 426.9 E(85289): 5.8e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:1-477)

               10        20        30        40        50        60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKN-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
               70        80        90       100       110       120

                                 120       130       140       150 
pF1KE0 ----------------------------LVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
                                   ::::::::::::::::::::::::::::::::
XP_011 SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
              130       140       150       160       170       180

             160       170       180       190       200       210 
pF1KE0 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
              190       200       210       220       230       240

             220       230       240       250       260       270 
pF1KE0 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
              250       260       270       280       290       300

             280       290       300       310       320       330 
pF1KE0 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
              310       320       330       340       350       360

             340       350       360       370       380       390 
pF1KE0 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
              370       380       390       400       410       420

             400       410       420       430       440        
pF1KE0 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
              430       440       450       460       470       

>>NP_001135864 (OMIM: 312090) P3 protein isoform 1 precu  (477 aa)
 initn: 2083 init1: 2083 opt: 2083  Z-score: 2256.7  bits: 426.9 E(85289): 5.8e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:1-477)

               10        20        30        40        50        60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKN-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_001 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
               70        80        90       100       110       120

                                 120       130       140       150 
pF1KE0 ----------------------------LVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
                                   ::::::::::::::::::::::::::::::::
NP_001 SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
              130       140       150       160       170       180

             160       170       180       190       200       210 
pF1KE0 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
              190       200       210       220       230       240

             220       230       240       250       260       270 
pF1KE0 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
              250       260       270       280       290       300

             280       290       300       310       320       330 
pF1KE0 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
              310       320       330       340       350       360

             340       350       360       370       380       390 
pF1KE0 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
              370       380       390       400       410       420

             400       410       420       430       440        
pF1KE0 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
              430       440       450       460       470       

>>NP_062822 (OMIM: 312090) P3 protein isoform 1 precurso  (477 aa)
 initn: 2083 init1: 2083 opt: 2083  Z-score: 2256.7  bits: 426.9 E(85289): 5.8e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:1-477)

               10        20        30        40        50        60
pF1KE0 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KE0 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKN-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_062 TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
               70        80        90       100       110       120

                                 120       130       140       150 
pF1KE0 ----------------------------LVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
                                   ::::::::::::::::::::::::::::::::
NP_062 SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
              130       140       150       160       170       180

             160       170       180       190       200       210 
pF1KE0 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
              190       200       210       220       230       240

             220       230       240       250       260       270 
pF1KE0 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
              250       260       270       280       290       300

             280       290       300       310       320       330 
pF1KE0 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
              310       320       330       340       350       360

             340       350       360       370       380       390 
pF1KE0 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
              370       380       390       400       410       420

             400       410       420       430       440        
pF1KE0 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
              430       440       450       460       470       

>>XP_005277970 (OMIM: 312090) PREDICTED: P3 protein isof  (532 aa)
 initn: 2083 init1: 2083 opt: 2083  Z-score: 2256.1  bits: 426.9 E(85289): 6.3e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:56-532)

                                             10        20        30
pF1KE0                               MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
                                     ::::::::::::::::::::::::::::::
XP_005 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
          30        40        50        60        70        80     

               40        50        60        70        80        90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
          90       100       110       120       130       140     

              100       110                                    120 
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKN-----------------------------LV
       :::::::::::::::::::::::::::::                             ::
XP_005 QYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSIHSGLAGLAPLHIQLV
         150       160       170       180       190       200     

             130       140       150       160       170       180 
pF1KE0 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
         210       220       230       240       250       260     

             190       200       210       220       230       240 
pF1KE0 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
         270       280       290       300       310       320     

             250       260       270       280       290       300 
pF1KE0 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
         330       340       350       360       370       380     

             310       320       330       340       350       360 
pF1KE0 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
         390       400       410       420       430       440     

             370       380       390       400       410       420 
pF1KE0 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
         450       460       470       480       490       500     

             430       440        
pF1KE0 IVALSGTSEMLALVIGHFIYSSLFPVP
       :::::::::::::::::::::::::::
XP_005 IVALSGTSEMLALVIGHFIYSSLFPVP
         510       520       530  

>>XP_011529502 (OMIM: 312090) PREDICTED: P3 protein isof  (532 aa)
 initn: 2083 init1: 2083 opt: 2083  Z-score: 2256.1  bits: 426.9 E(85289): 6.3e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:56-532)

                                             10        20        30
pF1KE0                               MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
                                     ::::::::::::::::::::::::::::::
XP_011 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
          30        40        50        60        70        80     

               40        50        60        70        80        90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
          90       100       110       120       130       140     

              100       110                                    120 
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKN-----------------------------LV
       :::::::::::::::::::::::::::::                             ::
XP_011 QYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSIHSGLAGLAPLHIQLV
         150       160       170       180       190       200     

             130       140       150       160       170       180 
pF1KE0 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
         210       220       230       240       250       260     

             190       200       210       220       230       240 
pF1KE0 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
         270       280       290       300       310       320     

             250       260       270       280       290       300 
pF1KE0 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
         330       340       350       360       370       380     

             310       320       330       340       350       360 
pF1KE0 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
         390       400       410       420       430       440     

             370       380       390       400       410       420 
pF1KE0 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
         450       460       470       480       490       500     

             430       440        
pF1KE0 IVALSGTSEMLALVIGHFIYSSLFPVP
       :::::::::::::::::::::::::::
XP_011 IVALSGTSEMLALVIGHFIYSSLFPVP
         510       520       530  

>>XP_006724910 (OMIM: 312090) PREDICTED: P3 protein isof  (570 aa)
 initn: 2083 init1: 2083 opt: 2083  Z-score: 2255.7  bits: 426.9 E(85289): 6.6e-119
Smith-Waterman score: 2803; 93.9% identity (93.9% similar) in 477 aa overlap (1-448:94-570)

                                             10        20        30
pF1KE0                               MVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
                                     ::::::::::::::::::::::::::::::
XP_006 PFSGQPNSTSGDVLLSRRGPGHAIRPPGRAMVLMQDKGSSQQWPGLGGEGGGTGPLSMLR
            70        80        90       100       110       120   

               40        50        60        70        80        90
pF1KE0 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISS
           130       140       150       160       170       180   

              100       110                                    120 
pF1KE0 QYPGQANRTAPGPMLRVTSLDTEVLTIKN-----------------------------LV
       :::::::::::::::::::::::::::::                             ::
XP_006 QYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSIHSGLAGLAPLHIQLV
           190       200       210       220       230       240   

             130       140       150       160       170       180 
pF1KE0 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCK
           250       260       270       280       290       300   

             190       200       210       220       230       240 
pF1KE0 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGS
           310       320       330       340       350       360   

             250       260       270       280       290       300 
pF1KE0 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILGTLLFI
           370       380       390       400       410       420   

             310       320       330       340       350       360 
pF1KE0 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAGIRLPIVLVGI
           430       440       450       460       470       480   

             370       380       390       400       410       420 
pF1KE0 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPF
           490       500       510       520       530       540   

             430       440        
pF1KE0 IVALSGTSEMLALVIGHFIYSSLFPVP
       :::::::::::::::::::::::::::
XP_006 IVALSGTSEMLALVIGHFIYSSLFPVP
           550       560       570

>>NP_932069 (OMIM: 613366) solute carrier family 10 memb  (377 aa)
 initn: 454 init1: 357 opt: 452  Z-score: 494.4  bits: 100.4 E(85289): 8.5e-21
Smith-Waterman score: 452; 31.7% identity (63.5% similar) in 271 aa overlap (143-408:12-278)

            120       130       140       150       160       170  
pF1KE0 EVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIF
                                     ::...   : . :   ..  ... ..  ..
NP_932                    MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVM
                                  10        20        30        40 

              180       190       200       210       220       230
pF1KE0 VN--KCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLI
       ..    :.::.::.. : . .. :  . .::: :: .::. :.:.:  : :  . :....
NP_932 MGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVL
              50        60        70        80        90       100 

              240       250       260       270       280       290
pF1KE0 ITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVP
       :    :::  : .:.. . ::. :.::::  ::::: :..::   .:.   :....: .:
NP_932 IMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIP
             110       120       130       140       150       160 

              300       310       320       330       340       350
pF1KE0 ISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILA
        ..:  ::. ..::.: :: .. . :: :...:..    . ::::    ..   :: .  
NP_932 YQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLL----VVAVAGVVLAK
             170       180       190       200           210       

                 360       370       380       390       400       
pF1KE0 GI---RLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLS
       :     . .. ...  ::.: ..:. ::   .    . ::.:.:.:.::  . ..:::::
NP_932 GSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLS
       220       230       240       250       260       270       

       410       420       430       440                           
pF1KE0 LRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP                   
       .                                                           
NP_932 FTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTS
       280       290       300       310       320       330       

>>NP_003040 (OMIM: 182396) sodium/bile acid cotransporte  (349 aa)
 initn: 409 init1: 271 opt: 438  Z-score: 479.7  bits: 97.6 E(85289): 5.6e-20
Smith-Waterman score: 438; 33.1% identity (65.7% similar) in 248 aa overlap (166-408:30-274)

         140       150       160       170       180       190     
pF1KE0 DFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQ
                                     .:. ..:    :.:: .:.  .:. . .:.
NP_003  MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPK
                10        20        30        40        50         

         200       210       220       230       240       250     
pF1KE0 PMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLA
        . ..:..:. .::: ::...::: : .  ::....   ::::. : .::: . ::..:.
NP_003 GLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLS
      60        70        80        90       100       110         

         260       270       280        290       300       310    
pF1KE0 ISMTFLSTVAATGFLPLSSAIYSRLLSIHETL-HVPISKILGTLLFIAIPIAVGVLIKSK
       : ::  ::  : :..::   :::: .   .   .:: . :. .:... :: ..:...:::
NP_003 IVMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSK
     120       130       140       150       160       170         

          320       330       340           350       360       370
pF1KE0 LPKFSQLLLQVVKPFSFVLLLGGLFL----AYRMGVFILAGIRLPIVLVGITVPLVGLLV
        :   : .  :.:   ...:: .. .    :  .:  :. ..   .. ..  .:..:.:.
NP_003 RP---QYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLL
     180          190       200       210       220       230      

              380       390       400       410       420       430
pF1KE0 GYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSE
       :: :.. . :    :::::.:.: ::  :  ..:....                      
NP_003 GYVLSALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGE
        240       250       260       270       280       290      

              440                                           
pF1KE0 MLALVIGHFIYSSLFPVP                                   
                                                            
NP_003 GLLLIAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA
        300       310       320       330       340         




448 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 08:11:15 2016 done: Thu Nov  3 08:11:17 2016
 Total Scan time:  9.470 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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