Result of FASTA (omim) for
pF1KE0194
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0194, 181 aa
1>>>pF1KE0194 181 - 181 aa - 181 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9215+/-0.000345; mu= 10.3065+/- 0.022
mean_var=80.5695+/-15.669, 0's: 0 Z-trim(115.3): 160 B-trim: 99 in 2/51
Lambda= 0.142886
statistics sampled from 25506 (25668) to 25506 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.301), width: 16
Scan time: 5.440
The best scores are: opt bits E(85289)
NP_003608 (OMIM: 145500,603276) regulator of G-pro ( 181) 1184 253.2 1.7e-67
NP_001241678 (OMIM: 145500,603276) regulator of G- ( 185) 1166 249.5 2.3e-66
NP_005604 (OMIM: 602516) regulator of G-protein si ( 205) 637 140.4 1.7e-33
NP_001095915 (OMIM: 602516) regulator of G-protein ( 302) 637 140.5 2.3e-33
NP_002919 (OMIM: 602514) regulator of G-protein si ( 202) 593 131.4 8.9e-31
NP_001095920 (OMIM: 607189) regulator of G-protein ( 180) 591 130.9 1.1e-30
XP_016858126 (OMIM: 607189) PREDICTED: regulator o ( 180) 591 130.9 1.1e-30
XP_016858125 (OMIM: 607189) PREDICTED: regulator o ( 180) 591 130.9 1.1e-30
XP_016858124 (OMIM: 607189) PREDICTED: regulator o ( 180) 591 130.9 1.1e-30
XP_005245612 (OMIM: 607189) PREDICTED: regulator o ( 180) 591 130.9 1.1e-30
XP_011508392 (OMIM: 607189) PREDICTED: regulator o ( 180) 591 130.9 1.1e-30
XP_011508393 (OMIM: 607189) PREDICTED: regulator o ( 178) 585 129.7 2.5e-30
XP_011508391 (OMIM: 607189) PREDICTED: regulator o ( 198) 585 129.7 2.8e-30
XP_016858122 (OMIM: 607189) PREDICTED: regulator o ( 198) 585 129.7 2.8e-30
NP_203131 (OMIM: 607189) regulator of G-protein si ( 198) 585 129.7 2.8e-30
XP_016858123 (OMIM: 607189) PREDICTED: regulator o ( 198) 585 129.7 2.8e-30
XP_016858120 (OMIM: 607189) PREDICTED: regulator o ( 198) 585 129.7 2.8e-30
XP_016858121 (OMIM: 607189) PREDICTED: regulator o ( 198) 585 129.7 2.8e-30
NP_652760 (OMIM: 602189) regulator of G-protein si ( 311) 562 125.1 1.1e-28
XP_011517198 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_011517203 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_006717293 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_016870494 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_016870495 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_011517200 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_006717289 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_011517199 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
XP_011517202 (OMIM: 602189) PREDICTED: regulator o ( 519) 558 124.4 2.9e-28
NP_001269851 (OMIM: 602189) regulator of G-protein ( 519) 558 124.4 2.9e-28
NP_001263189 (OMIM: 602189) regulator of G-protein ( 519) 558 124.4 2.9e-28
XP_006717288 (OMIM: 602189) PREDICTED: regulator o ( 521) 558 124.4 3e-28
NP_001309144 (OMIM: 602189) regulator of G-protein ( 537) 558 124.4 3e-28
XP_011517196 (OMIM: 602189) PREDICTED: regulator o ( 545) 558 124.4 3.1e-28
NP_001263190 (OMIM: 602189) regulator of G-protein ( 591) 558 124.4 3.3e-28
XP_006717285 (OMIM: 602189) PREDICTED: regulator o ( 824) 558 124.5 4.4e-28
NP_570613 (OMIM: 602189) regulator of G-protein si ( 917) 558 124.5 4.8e-28
XP_016870493 (OMIM: 602189) PREDICTED: regulator o ( 961) 558 124.5 5e-28
XP_006717283 (OMIM: 602189) PREDICTED: regulator o (1086) 558 124.5 5.5e-28
NP_001269852 (OMIM: 602189) regulator of G-protein (1088) 558 124.5 5.5e-28
XP_006717282 (OMIM: 602189) PREDICTED: regulator o (1094) 558 124.5 5.5e-28
XP_016870492 (OMIM: 602189) PREDICTED: regulator o (1157) 558 124.5 5.8e-28
NP_652759 (OMIM: 602189) regulator of G-protein si (1198) 558 124.5 6e-28
NP_001263191 (OMIM: 602189) regulator of G-protein ( 168) 545 121.4 7.3e-28
NP_602299 (OMIM: 602189) regulator of G-protein si ( 168) 545 121.4 7.3e-28
NP_001106851 (OMIM: 602516) regulator of G-protein ( 187) 545 121.4 8e-28
NP_570138 (OMIM: 607192) regulator of G-protein si ( 235) 543 121.1 1.3e-27
NP_002914 (OMIM: 600861) regulator of G-protein si ( 211) 532 118.8 5.6e-27
NP_001034241 (OMIM: 612407) regulator of G-protein ( 152) 503 112.7 2.7e-25
NP_001241677 (OMIM: 145500,603276) regulator of G- ( 73) 466 105.0 2.9e-23
NP_001182232 (OMIM: 145500,603276) regulator of G- ( 73) 466 105.0 2.9e-23
>>NP_003608 (OMIM: 145500,603276) regulator of G-protein (181 aa)
initn: 1184 init1: 1184 opt: 1184 Z-score: 1332.7 bits: 253.2 E(85289): 1.7e-67
Smith-Waterman score: 1184; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
130 140 150 160 170 180
pF1KE0 K
:
NP_003 K
>>NP_001241678 (OMIM: 145500,603276) regulator of G-prot (185 aa)
initn: 889 init1: 850 opt: 1166 Z-score: 1312.5 bits: 249.5 E(85289): 2.3e-66
Smith-Waterman score: 1166; 97.8% identity (97.8% similar) in 185 aa overlap (1-181:1-185)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 IQTEAPKEV----NIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFY
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQTEAPKEVGLWVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFY
130 140 150 160 170 180
180
pF1KE0 QELIK
:::::
NP_001 QELIK
>>NP_005604 (OMIM: 602516) regulator of G-protein signal (205 aa)
initn: 622 init1: 471 opt: 637 Z-score: 722.4 bits: 140.4 E(85289): 1.7e-33
Smith-Waterman score: 637; 53.3% identity (82.8% similar) in 180 aa overlap (1-180:1-178)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
::::::.:: :::. ::..: .::.:::: :: . .:.: .: . :..: .:. .
NP_005 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSC-EHNSSHNKK-DKVVICQRVSQEEVKK
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
: .::..:.... :::.::.:::::.::::..:::.::.:::::::.:.. :::.::.::
NP_005 WAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
:...: ::::.: :.. : .:..::... :: :::.: :::::: ::..:.:: .:.
NP_005 ISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV
120 130 140 150 160 170
pF1KE0 K
NP_005 NPSSCGAEKQKGAKSSADCASLVPQCA
180 190 200
>>NP_001095915 (OMIM: 602516) regulator of G-protein sig (302 aa)
initn: 622 init1: 471 opt: 637 Z-score: 719.9 bits: 140.5 E(85289): 2.3e-33
Smith-Waterman score: 637; 53.3% identity (82.8% similar) in 180 aa overlap (1-180:98-275)
10 20 30
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKP
::::::.:: :::. ::..: .::.::::
NP_001 GEEAKYAQSRSHSSSCRISFLLANSKLLNKMCKGLAGLPASCLRSAKDMKHRLGFLLQKS
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE0 DSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEEN
:: . .:.: .: . :..: .:. .: .::..:.... :::.::.:::::.::::
NP_001 DSC-EHNSSHNKK-DKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEEN
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE0 LEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSS
..:::.::.:::::::.:.. :::.::.:::...: ::::.: :.. : .:..::...
NP_001 IDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITC
190 200 210 220 230 240
160 170 180
pF1KE0 FDMAQKRIHALMEKDSLPRFVRSEFYQELIK
:: :::.: :::::: ::..:.:: .:.
NP_001 FDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
250 260 270 280 290 300
>>NP_002919 (OMIM: 602514) regulator of G-protein signal (202 aa)
initn: 608 init1: 470 opt: 593 Z-score: 673.5 bits: 131.4 E(85289): 8.9e-31
Smith-Waterman score: 593; 51.1% identity (77.8% similar) in 180 aa overlap (1-179:1-180)
10 20 30 40 50
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYN-EKPEKPAKTQKTSLDEAL
::. :::.: .:::::::.: .:::.:.: . : . : : .: ... ...:
NP_002 MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE
::.:.: ::... :.:.:..:::.::::::::::.:::..:::.: .:.: .:.::.::
NP_002 GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL
:: .:::::::::: :...: :: . . :: :: . ..:::::: :::..: :..:
NP_002 FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
130 140 150 160 170 180
180
pF1KE0 IK
NP_002 AAQASAASATLSSCSLDEPSHT
190 200
>>NP_001095920 (OMIM: 607189) regulator of G-protein sig (180 aa)
initn: 569 init1: 524 opt: 591 Z-score: 672.0 bits: 130.9 E(85289): 1.1e-30
Smith-Waterman score: 591; 51.8% identity (80.7% similar) in 166 aa overlap (15-180:9-172)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
: : .. .:: : .: :: .:.. .::.. : . : .:: .
NP_001 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATR
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
: ::.: ::...::.:.:..:::.::::::::::.:::..:: .: ::.. ::..:.:::
NP_001 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: :::.::..: .:.
NP_001 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
120 130 140 150 160 170
pF1KE0 K
NP_001 SQSQRRLS
180
>>XP_016858126 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 569 init1: 524 opt: 591 Z-score: 672.0 bits: 130.9 E(85289): 1.1e-30
Smith-Waterman score: 591; 51.8% identity (80.7% similar) in 166 aa overlap (15-180:9-172)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
: : .. .:: : .: :: .:.. .::.. : . : .:: .
XP_016 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATR
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
: ::.: ::...::.:.:..:::.::::::::::.:::..:: .: ::.. ::..:.:::
XP_016 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: :::.::..: .:.
XP_016 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
120 130 140 150 160 170
pF1KE0 K
XP_016 SQSQRRLS
180
>>XP_016858125 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 569 init1: 524 opt: 591 Z-score: 672.0 bits: 130.9 E(85289): 1.1e-30
Smith-Waterman score: 591; 51.8% identity (80.7% similar) in 166 aa overlap (15-180:9-172)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
: : .. .:: : .: :: .:.. .::.. : . : .:: .
XP_016 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATR
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
: ::.: ::...::.:.:..:::.::::::::::.:::..:: .: ::.. ::..:.:::
XP_016 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: :::.::..: .:.
XP_016 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
120 130 140 150 160 170
pF1KE0 K
XP_016 SQSQRRLS
180
>>XP_016858124 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 569 init1: 524 opt: 591 Z-score: 672.0 bits: 130.9 E(85289): 1.1e-30
Smith-Waterman score: 591; 51.8% identity (80.7% similar) in 166 aa overlap (15-180:9-172)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
: : .. .:: : .: :: .:.. .::.. : . : .:: .
XP_016 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATR
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
: ::.: ::...::.:.:..:::.::::::::::.:::..:: .: ::.. ::..:.:::
XP_016 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: :::.::..: .:.
XP_016 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
120 130 140 150 160 170
pF1KE0 K
XP_016 SQSQRRLS
180
>>XP_005245612 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 569 init1: 524 opt: 591 Z-score: 672.0 bits: 130.9 E(85289): 1.1e-30
Smith-Waterman score: 591; 51.8% identity (80.7% similar) in 166 aa overlap (15-180:9-172)
10 20 30 40 50 60
pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
: : .. .:: : .: :: .:.. .::.. : . : .:: .
XP_005 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATR
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
: ::.: ::...::.:.:..:::.::::::::::.:::..:: .: ::.. ::..:.:::
XP_005 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: :::.::..: .:.
XP_005 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
120 130 140 150 160 170
pF1KE0 K
XP_005 SQSQRRLS
180
181 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:41:38 2016 done: Thu Nov 3 21:41:39 2016
Total Scan time: 5.440 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]