Result of FASTA (omim) for pF1KE0172
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0172, 317 aa
  1>>>pF1KE0172 317 - 317 aa - 317 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7094+/-0.000338; mu= 19.4602+/- 0.021
 mean_var=69.9581+/-14.038, 0's: 0 Z-trim(113.9): 21  B-trim: 44 in 1/55
 Lambda= 0.153340
 statistics sampled from 23434 (23441) to 23434 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.275), width:  16
 Scan time:  7.040

The best scores are:                                      opt bits E(85289)
NP_005389 (OMIM: 602999) protein phosphatase 1 reg ( 317) 2202 496.1 3.8e-140
NP_078883 (OMIM: 610541) protein phosphatase 1 reg ( 285)  773 180.0 5.1e-45
XP_006716316 (OMIM: 610541) PREDICTED: protein pho ( 285)  773 180.0 5.1e-45
NP_001188258 (OMIM: 610541) protein phosphatase 1  ( 285)  773 180.0 5.1e-45
XP_016869324 (OMIM: 610541) PREDICTED: protein pho ( 285)  773 180.0 5.1e-45
NP_006233 (OMIM: 603326) protein phosphatase 1 reg ( 299)  340 84.2 3.6e-16
NP_002702 (OMIM: 125853,600917,604367) protein pho (1122)  337 84.1 1.5e-15


>>NP_005389 (OMIM: 602999) protein phosphatase 1 regulat  (317 aa)
 initn: 2202 init1: 2202 opt: 2202  Z-score: 2637.1  bits: 496.1 E(85289): 3.8e-140
Smith-Waterman score: 2202; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)

               10        20        30        40        50        60
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL
              250       260       270       280       290       300

              310       
pF1KE0 FPEWQSWGRMENLASYR
       :::::::::::::::::
NP_005 FPEWQSWGRMENLASYR
              310       

>>NP_078883 (OMIM: 610541) protein phosphatase 1 regulat  (285 aa)
 initn: 689 init1: 529 opt: 773  Z-score: 929.2  bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)

               10        20         30        40        50         
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
                         .: ::. .:  :.:  : ...     ..:  .   .  :::.
NP_078                   MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
                                 10               20        30     

      60          70        80        90       100       110       
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
        :...  :..:...     .....:::: :::..::.:: ..:::.. ..:  :. :.. 
NP_078 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
          40        50        60        70        80          90   

       120       130       140       150       160       170       
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
       .: :   .:   : ....::: :::.:::.::...: . :::::: :......:::::.:
NP_078 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
           100       110       120       130       140       150   

       180       190       200       210       220       230       
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
       ..::: :.::.:::.::.:::  : :.:..:.:.: ::::: :.::  : . ...:: . 
NP_078 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
           160       170       180       190       200       210   

       240       250       260       270       280       290       
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
       :. :::..::.: :.::::.... :  ..: .  :      ...:   .    ::::: .
NP_078 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
           220       230         240             250       260     

       300       310       
pF1KE0 SGLFPEWQSWGRMENLASYR
        :::::: :.  .:.:. : 
NP_078 YGLFPEWPSYLGYEKLGPYY
         270       280     

>>XP_006716316 (OMIM: 610541) PREDICTED: protein phospha  (285 aa)
 initn: 689 init1: 529 opt: 773  Z-score: 929.2  bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)

               10        20         30        40        50         
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
                         .: ::. .:  :.:  : ...     ..:  .   .  :::.
XP_006                   MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
                                 10               20        30     

      60          70        80        90       100       110       
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
        :...  :..:...     .....:::: :::..::.:: ..:::.. ..:  :. :.. 
XP_006 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
          40        50        60        70        80          90   

       120       130       140       150       160       170       
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
       .: :   .:   : ....::: :::.:::.::...: . :::::: :......:::::.:
XP_006 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
           100       110       120       130       140       150   

       180       190       200       210       220       230       
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
       ..::: :.::.:::.::.:::  : :.:..:.:.: ::::: :.::  : . ...:: . 
XP_006 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
           160       170       180       190       200       210   

       240       250       260       270       280       290       
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
       :. :::..::.: :.::::.... :  ..: .  :      ...:   .    ::::: .
XP_006 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
           220       230         240             250       260     

       300       310       
pF1KE0 SGLFPEWQSWGRMENLASYR
        :::::: :.  .:.:. : 
XP_006 YGLFPEWPSYLGYEKLGPYY
         270       280     

>>NP_001188258 (OMIM: 610541) protein phosphatase 1 regu  (285 aa)
 initn: 689 init1: 529 opt: 773  Z-score: 929.2  bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)

               10        20         30        40        50         
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
                         .: ::. .:  :.:  : ...     ..:  .   .  :::.
NP_001                   MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
                                 10               20        30     

      60          70        80        90       100       110       
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
        :...  :..:...     .....:::: :::..::.:: ..:::.. ..:  :. :.. 
NP_001 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
          40        50        60        70        80          90   

       120       130       140       150       160       170       
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
       .: :   .:   : ....::: :::.:::.::...: . :::::: :......:::::.:
NP_001 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
           100       110       120       130       140       150   

       180       190       200       210       220       230       
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
       ..::: :.::.:::.::.:::  : :.:..:.:.: ::::: :.::  : . ...:: . 
NP_001 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
           160       170       180       190       200       210   

       240       250       260       270       280       290       
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
       :. :::..::.: :.::::.... :  ..: .  :      ...:   .    ::::: .
NP_001 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
           220       230         240             250       260     

       300       310       
pF1KE0 SGLFPEWQSWGRMENLASYR
        :::::: :.  .:.:. : 
NP_001 YGLFPEWPSYLGYEKLGPYY
         270       280     

>>XP_016869324 (OMIM: 610541) PREDICTED: protein phospha  (285 aa)
 initn: 689 init1: 529 opt: 773  Z-score: 929.2  bits: 180.0 E(85289): 5.1e-45
Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284)

               10        20         30        40        50         
pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK
                         .: ::. .:  :.:  : ...     ..:  .   .  :::.
XP_016                   MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR
                                 10               20        30     

      60          70        80        90       100       110       
pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL
        :...  :..:...     .....:::: :::..::.:: ..:::.. ..:  :. :.. 
XP_016 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT
          40        50        60        70        80          90   

       120       130       140       150       160       170       
pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN
       .: :   .:   : ....::: :::.:::.::...: . :::::: :......:::::.:
XP_016 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN
           100       110       120       130       140       150   

       180       190       200       210       220       230       
pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS
       ..::: :.::.:::.::.:::  : :.:..:.:.: ::::: :.::  : . ...:: . 
XP_016 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY
           160       170       180       190       200       210   

       240       250       260       270       280       290       
pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA
       :. :::..::.: :.::::.... :  ..: .  :      ...:   .    ::::: .
XP_016 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS
           220       230         240             250       260     

       300       310       
pF1KE0 SGLFPEWQSWGRMENLASYR
        :::::: :.  .:.:. : 
XP_016 YGLFPEWPSYLGYEKLGPYY
         270       280     

>>NP_006233 (OMIM: 603326) protein phosphatase 1 regulat  (299 aa)
 initn: 270 init1: 155 opt: 340  Z-score: 411.2  bits: 84.2 E(85289): 3.6e-16
Smith-Waterman score: 344; 29.5% identity (58.5% similar) in 275 aa overlap (10-265:19-289)

                        10         20          30             40   
pF1KE0          MSCTRMIQVLDPRPLTS-SVMPVDVAM--RLCL-----AHSPPVKSFLGPY
                         : :: :.  : .   ::.  : :      ...::     .  
NP_006 MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGC
               10        20        30        40        50        60

            50        60        70        80         90       100  
pF1KE0 DEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKK-RVVFADSKGLSLTAIHVFS
       :   :  .. . . : :  . ..:: .     :  . ..: :: :::. :: :. ..:: 
NP_006 DPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVF-
               70        80        90       100       110          

            110        120        130         140       150        
pF1KE0 DLPEEPAWDLQ-FDLLDLN-DISSALKHHEE--KNLILDFPQPSTDYLSFRSHFQKNFVC
       .  ..:.  :. .. : .: :.  . .  :   . :. ::: : ..  .:  ..:...::
NP_006 NAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPP-VEAADFGERLQRQLVC
     120       130       140       150       160        170        

      160       170       180       190       200         210      
pF1KE0 LENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYG--GTDSDTF
       ::  . ..  ..:::.: ::.:::.: .: ::..:.. :    .  ..  :  ::. :.:
NP_006 LERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRS-THEAVARWRGPAGPEGTE-DVF
      180       190       200       210        220       230       

        220        230       240       250          260       270  
pF1KE0 SFAIDLPP-VIPTEQKIEFCISYHANGQVFWDNNDGQNYRIV---HVQWKPDGVQTQMAP
       .:.. .:: ..   ....: . :.. :  .::::: ..: ..   :.   : :       
NP_006 TFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWI
        240       250       260       270       280       290      

            280       290       300       310       
pF1KE0 QDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR
                                                    
NP_006 HFI                                          
                                                    

>>NP_002702 (OMIM: 125853,600917,604367) protein phospha  (1122 aa)
 initn: 272 init1: 229 opt: 337  Z-score: 400.2  bits: 84.1 E(85289): 1.5e-15
Smith-Waterman score: 337; 33.7% identity (63.2% similar) in 190 aa overlap (83-267:62-242)

             60        70        80        90       100       110  
pF1KE0 NKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDL
                                     .:: :::: :..:.... : :  : :. . 
NP_002 TFQPGFSPQPSRRGSDSSEDIYLDTPSSGTRRVSFADSFGFNLVSVKEF-DCWELPSAST
              40        50        60        70        80         90

            120       130         140       150       160       170
pF1KE0 QFDLLDLNDISSALKHHEEKNL--ILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVT
        :::      .. . : ::  :  ..:.:. . : .. . ..:: ..   .  :   .. 
NP_002 TFDL------GTDIFHTEEYVLAPLFDLPSSKEDLMQ-QLQIQKAILESTESLLGSTSIK
                    100       110       120        130       140   

              180       190       200       210       220          
pF1KE0 GTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDL-PPVIPTE
       : ..: :::::: : .:...:.:... :.   :. :   : ..: ::: : : ::     
NP_002 GIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNSCDG-ETDQFSFKIVLVPPYQKDG
           150       160       170       180        190       200  

     230       240       250         260       270       280       
pF1KE0 QKIEFCISYHANGQVFWDNNDGQNYRIV--HVQWKPDGVQTQMAPQDCAFHQTSPKTELE
       .:.:::: :...  .::.::.: :: ..  . . .:. :.                    
NP_002 SKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEPVKPWKEVPNRQIKGCLKVKSSK
            210       220       230       240       250       260  

       290       300       310                                     
pF1KE0 STIFGSPRLASGLFPEWQSWGRMENLASYR                              
                                                                   
NP_002 EESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELM
            270       280       290       300       310       320  




317 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:55:06 2016 done: Thu Nov  3 22:55:07 2016
 Total Scan time:  7.040 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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