Result of FASTA (omim) for pF1KB6309
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6309, 258 aa
  1>>>pF1KB6309 258 - 258 aa - 258 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5777+/-0.000271; mu= 14.0753+/- 0.017
 mean_var=77.8823+/-15.685, 0's: 0 Z-trim(120.7): 13  B-trim: 3 in 1/55
 Lambda= 0.145330
 statistics sampled from 36250 (36263) to 36250 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.425), width:  16
 Scan time:  8.000

The best scores are:                                      opt bits E(85289)
NP_036220 (OMIM: 604951) 6-phosphogluconolactonase ( 258) 1700 365.1 7.2e-101
XP_011526199 (OMIM: 604951) PREDICTED: 6-phosphogl ( 170) 1072 233.3 2.2e-61
XP_016858355 (OMIM: 138090,604931) PREDICTED: GDH/ ( 435)  354 83.0 9.8e-16
XP_016858354 (OMIM: 138090,604931) PREDICTED: GDH/ ( 791)  354 83.2 1.6e-15
XP_006711115 (OMIM: 138090,604931) PREDICTED: GDH/ ( 791)  354 83.2 1.6e-15
NP_004276 (OMIM: 138090,604931) GDH/6PGL endoplasm ( 791)  354 83.2 1.6e-15
XP_005263597 (OMIM: 138090,604931) PREDICTED: GDH/ ( 800)  354 83.2 1.6e-15
NP_001269516 (OMIM: 138090,604931) GDH/6PGL endopl ( 802)  354 83.2 1.6e-15


>>NP_036220 (OMIM: 604951) 6-phosphogluconolactonase [Ho  (258 aa)
 initn: 1700 init1: 1700 opt: 1700  Z-score: 1931.9  bits: 365.1 E(85289): 7.2e-101
Smith-Waterman score: 1700; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)

               10        20        30        40        50        60
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL
              190       200       210       220       230       240

              250        
pF1KB6 DEAAARLLTVPFEKHSTL
       ::::::::::::::::::
NP_036 DEAAARLLTVPFEKHSTL
              250        

>>XP_011526199 (OMIM: 604951) PREDICTED: 6-phosphoglucon  (170 aa)
 initn: 1072 init1: 1072 opt: 1072  Z-score: 1223.0  bits: 233.3 E(85289): 2.2e-61
Smith-Waterman score: 1072; 100.0% identity (100.0% similar) in 162 aa overlap (97-258:9-170)

         70        80        90       100       110       120      
pF1KB6 PASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVEEAAEDY
                                     ::::::::::::::::::::::::::::::
XP_011                       MEKLRPEETHLLSRLPIPESQVITINPELPVEEAAEDY
                                     10        20        30        

        130       140       150       160       170       180      
pF1KB6 AKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRV
       40        50        60        70        80        90        

        190       200       210       220       230       240      
pF1KB6 TLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAAR
      100       110       120       130       140       150        

        250        
pF1KB6 LLTVPFEKHSTL
       ::::::::::::
XP_011 LLTVPFEKHSTL
      160       170

>>XP_016858355 (OMIM: 138090,604931) PREDICTED: GDH/6PGL  (435 aa)
 initn: 291 init1: 174 opt: 354  Z-score: 403.5  bits: 83.0 E(85289): 9.8e-16
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:199-432)

                                      10        20        30       
pF1KB6                        MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
                                     :.:..  :.:: . ::. .  .:.   :  
XP_016 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
      170       180       190       200         210         220    

         40        50        60         70        80        90     
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
       : ..: :.:::::    : ..:  :.:  : :   :.  : . ::: ::..  ::..   
XP_016 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
          230       240         250         260       270       280

         100       110           120         130       140         
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
       ..:::... ::  ..    . .. .: .::  .:. ::...     ..:   :::..::.
XP_016 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
              290       300       310       320          330       

     150       160       170       180       190       200         
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
       : :::: ::::. :   . :..:. .. ::. : .:..:.::..: :. :  .. :. : 
XP_016 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
       340       350       360        370       380       390      

     210        220       230       240       250        
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
        .   . .  .: .  : . : ::.:.: :..:  :              
XP_016 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG           
        400       410       420       430                

>>XP_016858354 (OMIM: 138090,604931) PREDICTED: GDH/6PGL  (791 aa)
 initn: 291 init1: 174 opt: 354  Z-score: 399.7  bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788)

                                      10        20        30       
pF1KB6                        MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
                                     :.:..  :.:: . ::. .  .:.   :  
XP_016 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
          530       540       550         560       570         580

         40        50        60         70        80        90     
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
       : ..: :.:::::    : ..:  :.:  : :   :.  : . ::: ::..  ::..   
XP_016 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
              590       600         610         620       630      

         100       110           120         130       140         
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
       ..:::... ::  ..    . .. .: .::  .:. ::...     ..:   :::..::.
XP_016 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
        640       650       660       670       680          690   

     150       160       170       180       190       200         
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
       : :::: ::::. :   . :..:. .. ::. : .:..:.::..: :. :  .. :. : 
XP_016 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
           700       710        720       730       740       750  

     210        220       230       240       250        
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
        .   . .  .: .  : . : ::.:.: :..:  :              
XP_016 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG           
            760       770       780       790            

>>XP_006711115 (OMIM: 138090,604931) PREDICTED: GDH/6PGL  (791 aa)
 initn: 291 init1: 174 opt: 354  Z-score: 399.7  bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788)

                                      10        20        30       
pF1KB6                        MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
                                     :.:..  :.:: . ::. .  .:.   :  
XP_006 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
          530       540       550         560       570         580

         40        50        60         70        80        90     
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
       : ..: :.:::::    : ..:  :.:  : :   :.  : . ::: ::..  ::..   
XP_006 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
              590       600         610         620       630      

         100       110           120         130       140         
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
       ..:::... ::  ..    . .. .: .::  .:. ::...     ..:   :::..::.
XP_006 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
        640       650       660       670       680          690   

     150       160       170       180       190       200         
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
       : :::: ::::. :   . :..:. .. ::. : .:..:.::..: :. :  .. :. : 
XP_006 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
           700       710        720       730       740       750  

     210        220       230       240       250        
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
        .   . .  .: .  : . : ::.:.: :..:  :              
XP_006 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG           
            760       770       780       790            

>>NP_004276 (OMIM: 138090,604931) GDH/6PGL endoplasmic b  (791 aa)
 initn: 291 init1: 174 opt: 354  Z-score: 399.7  bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788)

                                      10        20        30       
pF1KB6                        MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
                                     :.:..  :.:: . ::. .  .:.   :  
NP_004 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
          530       540       550         560       570         580

         40        50        60         70        80        90     
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
       : ..: :.:::::    : ..:  :.:  : :   :.  : . ::: ::..  ::..   
NP_004 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
              590       600         610         620       630      

         100       110           120         130       140         
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
       ..:::... ::  ..    . .. .: .::  .:. ::...     ..:   :::..::.
NP_004 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
        640       650       660       670       680          690   

     150       160       170       180       190       200         
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
       : :::: ::::. :   . :..:. .. ::. : .:..:.::..: :. :  .. :. : 
NP_004 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
           700       710        720       730       740       750  

     210        220       230       240       250        
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
        .   . .  .: .  : . : ::.:.: :..:  :              
NP_004 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG           
            760       770       780       790            

>>XP_005263597 (OMIM: 138090,604931) PREDICTED: GDH/6PGL  (800 aa)
 initn: 291 init1: 174 opt: 354  Z-score: 399.6  bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:564-797)

                                      10        20        30       
pF1KB6                        MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
                                     :.:..  :.:: . ::. .  .:.   :  
XP_005 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
           540       550       560         570       580           

         40        50        60         70        80        90     
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
       : ..: :.:::::    : ..:  :.:  : :   :.  : . ::: ::..  ::..   
XP_005 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
     590       600       610           620       630       640     

         100       110           120         130       140         
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
       ..:::... ::  ..    . .. .: .::  .:. ::...     ..:   :::..::.
XP_005 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
         650       660       670       680       690          700  

     150       160       170       180       190       200         
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
       : :::: ::::. :   . :..:. .. ::. : .:..:.::..: :. :  .. :. : 
XP_005 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
            710       720        730       740       750       760 

     210        220       230       240       250        
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
        .   . .  .: .  : . : ::.:.: :..:  :              
XP_005 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG           
             770       780       790       800           

>>NP_001269516 (OMIM: 138090,604931) GDH/6PGL endoplasmi  (802 aa)
 initn: 291 init1: 174 opt: 354  Z-score: 399.6  bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:566-799)

                                      10        20        30       
pF1KB6                        MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
                                     :.:..  :.:: . ::. .  .:.   :  
NP_001 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
         540       550       560       570         580         590 

         40        50        60         70        80        90     
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
       : ..: :.:::::    : ..:  :.:  : :   :.  : . ::: ::..  ::..   
NP_001 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
             600       610         620         630       640       

         100       110           120         130       140         
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
       ..:::... ::  ..    . .. .: .::  .:. ::...     ..:   :::..::.
NP_001 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
       650       660       670       680       690          700    

     150       160       170       180       190       200         
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
       : :::: ::::. :   . :..:. .. ::. : .:..:.::..: :. :  .. :. : 
NP_001 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
          710       720        730       740       750       760   

     210        220       230       240       250        
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
        .   . .  .: .  : . : ::.:.: :..:  :              
NP_001 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG           
           770       780       790       800             




258 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  9 12:17:34 2016 done: Wed Nov  9 12:17:35 2016
 Total Scan time:  8.000 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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