Result of FASTA (omim) for pF1KE0406
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0406, 341 aa
  1>>>pF1KE0406 341 - 341 aa - 341 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2822+/-0.000397; mu= 16.2118+/- 0.025
 mean_var=62.1531+/-12.534, 0's: 0 Z-trim(111.5): 24  B-trim: 439 in 2/48
 Lambda= 0.162683
 statistics sampled from 20131 (20151) to 20131 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.236), width:  16
 Scan time:  7.180

The best scores are:                                      opt bits E(85289)
NP_001302465 (OMIM: 179060,614111) pyruvate dehydr ( 341) 2277 543.1 3.2e-154
NP_000916 (OMIM: 179060,614111) pyruvate dehydroge ( 359) 2200 525.1 9.1e-149
NP_001166939 (OMIM: 179060,614111) pyruvate dehydr ( 341) 1434 345.3 1.1e-94
XP_011534328 (OMIM: 248600,248611) PREDICTED: 2-ox ( 322)  629 156.3 8.2e-38
NP_001305904 (OMIM: 248600,248611) 2-oxoisovalerat ( 322)  629 156.3 8.2e-38
NP_000047 (OMIM: 248600,248611) 2-oxoisovalerate d ( 392)  630 156.6 8.2e-38
NP_898871 (OMIM: 248600,248611) 2-oxoisovalerate d ( 392)  630 156.6 8.2e-38
XP_011534325 (OMIM: 248600,248611) PREDICTED: 2-ox ( 359)  561 140.4 5.7e-33
XP_005248813 (OMIM: 248600,248611) PREDICTED: 2-ox ( 360)  560 140.2 6.8e-33
XP_011534326 (OMIM: 248600,248611) PREDICTED: 2-ox ( 353)  559 139.9 7.8e-33
XP_011534327 (OMIM: 248600,248611) PREDICTED: 2-ox ( 350)  557 139.4 1.1e-32
NP_001139406 (OMIM: 300044) transketolase-like pro ( 540)  196 54.8   5e-07
NP_001139405 (OMIM: 300044) transketolase-like pro ( 590)  196 54.8 5.4e-07
NP_036385 (OMIM: 300044) transketolase-like protei ( 596)  196 54.8 5.4e-07
XP_011532357 (OMIM: 606781,617044) PREDICTED: tran ( 457)  147 43.3  0.0013
NP_001055 (OMIM: 606781,617044) transketolase isof ( 623)  147 43.3  0.0016
NP_001128527 (OMIM: 606781,617044) transketolase i ( 623)  147 43.3  0.0016
XP_011532356 (OMIM: 606781,617044) PREDICTED: tran ( 631)  147 43.3  0.0017
NP_001244957 (OMIM: 606781,617044) transketolase i ( 631)  147 43.3  0.0017


>>NP_001302465 (OMIM: 179060,614111) pyruvate dehydrogen  (341 aa)
 initn: 2277 init1: 2277 opt: 2277  Z-score: 2889.8  bits: 543.1 E(85289): 3.2e-154
Smith-Waterman score: 2277; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)

               10        20        30        40        50        60
pF1KE0 MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 PVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 VLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 EGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFL
              250       260       270       280       290       300

              310       320       330       340 
pF1KE0 DAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
       :::::::::::::::::::::::::::::::::::::::::
NP_001 DAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
              310       320       330       340 

>>NP_000916 (OMIM: 179060,614111) pyruvate dehydrogenase  (359 aa)
 initn: 2192 init1: 2192 opt: 2200  Z-score: 2791.8  bits: 525.1 E(85289): 9.1e-149
Smith-Waterman score: 2231; 95.0% identity (95.0% similar) in 359 aa overlap (1-341:1-359)

               10                          20        30        40  
pF1KE0 MAAVSGLVRRPLREV------------------TVRDAINQGMDEELERDEKVFLLGEEV
       :::::::::::::::                  :::::::::::::::::::::::::::
NP_000 MAAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEV
               10        20        30        40        50        60

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
               70        80        90       100       110       120

            110       120       130       140       150       160  
pF1KE0 DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
              130       140       150       160       170       180

            170       180       190       200       210       220  
pF1KE0 EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
              190       200       210       220       230       240

            230       240       250       260       270       280  
pF1KE0 SHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFG
              250       260       270       280       290       300

            290       300       310       320       330       340 
pF1KE0 VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
              310       320       330       340       350         

>>NP_001166939 (OMIM: 179060,614111) pyruvate dehydrogen  (341 aa)
 initn: 1419 init1: 1399 opt: 1434  Z-score: 1820.5  bits: 345.3 E(85289): 1.1e-94
Smith-Waterman score: 2059; 90.0% identity (90.0% similar) in 359 aa overlap (1-341:1-341)

               10                          20        30        40  
pF1KE0 MAAVSGLVRRPLREV------------------TVRDAINQGMDEELERDEKVFLLGEEV
       :::::::::::::::                  :::::::::::::::::::::::::::
NP_001 MAAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEV
               10        20        30        40        50        60

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
               70        80        90       100       110       120

            110       120       130       140       150       160  
pF1KE0 DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
       :::::::::::::::                  :::::::::::::::::::::::::::
NP_001 DQVINSAAKTYYMSG------------------VAAQHSQCFAAWYGHCPGLKVVSPWNS
              130                         140       150       160  

            170       180       190       200       210       220  
pF1KE0 EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
            170       180       190       200       210       220  

            230       240       250       260       270       280  
pF1KE0 SHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFG
            230       240       250       260       270       280  

            290       300       310       320       330       340 
pF1KE0 VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
            290       300       310       320       330       340 

>>XP_011534328 (OMIM: 248600,248611) PREDICTED: 2-oxoiso  (322 aa)
 initn: 509 init1: 178 opt: 629  Z-score: 799.8  bits: 156.3 E(85289): 8.2e-38
Smith-Waterman score: 629; 35.2% identity (66.4% similar) in 324 aa overlap (20-340:6-321)

               10        20        30        40        50        60
pF1KE0 MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYG
                          ......:. : .:  . ..::.:: . :... . ::  :::
XP_011               MNLFQSVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYG
                             10        20         30        40     

               70        80        90       100       110       120
pF1KE0 DKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQ
         :...::. :.:..:...: :..:   : :..  .. . :.::..: :::  : :: : 
XP_011 KDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLF
          50        60        70        80        90       100     

               130       140       150       160       170         
pF1KE0 PV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPV
           ...:.: :  .  :  :::   :...::::.::: : .  .::::. : :.:.:: 
XP_011 NCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPC
         110       120       130       140       150       160     

     180       190       200       210       220       230         
pF1KE0 VVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS
       . .: ...: .  :   :.  . . ::...:.. ..:. .:.:. .  : : .. .: ..
XP_011 IFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQV-HVIREVASMA
         170          180       190       200       210        220 

     240         250       260       270       280       290       
pF1KE0 KE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAF
       ::  :: ::::..::: : :..::  ::.::..:.  . .    : ..:: . ..:   :
XP_011 KEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQE-ECF
             230       240       250       260       270        280

       300       310       320       330       340 
pF1KE0 NFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
         :.::  :: : :.:.:.  :.:   ::.      :..: .: 
XP_011 LNLEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMINY
              290         300       310       320  

>>NP_001305904 (OMIM: 248600,248611) 2-oxoisovalerate de  (322 aa)
 initn: 509 init1: 178 opt: 629  Z-score: 799.8  bits: 156.3 E(85289): 8.2e-38
Smith-Waterman score: 629; 35.2% identity (66.4% similar) in 324 aa overlap (20-340:6-321)

               10        20        30        40        50        60
pF1KE0 MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYG
                          ......:. : .:  . ..::.:: . :... . ::  :::
NP_001               MNLFQSVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYG
                             10        20         30        40     

               70        80        90       100       110       120
pF1KE0 DKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQ
         :...::. :.:..:...: :..:   : :..  .. . :.::..: :::  : :: : 
NP_001 KDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLF
          50        60        70        80        90       100     

               130       140       150       160       170         
pF1KE0 PV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPV
           ...:.: :  .  :  :::   :...::::.::: : .  .::::. : :.:.:: 
NP_001 NCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPC
         110       120       130       140       150       160     

     180       190       200       210       220       230         
pF1KE0 VVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS
       . .: ...: .  :   :.  . . ::...:.. ..:. .:.:. .  : : .. .: ..
NP_001 IFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQV-HVIREVASMA
         170          180       190       200       210        220 

     240         250       260       270       280       290       
pF1KE0 KE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAF
       ::  :: ::::..::: : :..::  ::.::..:.  . .    : ..:: . ..:   :
NP_001 KEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQE-ECF
             230       240       250       260       270        280

       300       310       320       330       340 
pF1KE0 NFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
         :.::  :: : :.:.:.  :.:   ::.      :..: .: 
NP_001 LNLEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMINY
              290         300       310       320  

>>NP_000047 (OMIM: 248600,248611) 2-oxoisovalerate dehyd  (392 aa)
 initn: 464 init1: 178 opt: 630  Z-score: 799.8  bits: 156.6 E(85289): 8.2e-38
Smith-Waterman score: 630; 34.4% identity (66.8% similar) in 331 aa overlap (13-340:69-391)

                                 10        20        30        40  
pF1KE0                   MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
                                     ..... .......:. : .:  . ..::.:
NP_000 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
       40        50        60        70        80        90        

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       : . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.
NP_000 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
       100       110       120       130       140       150       

            110       120        130       140       150       160 
pF1KE0 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
       ::..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : .
NP_000 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
       160       170       180       190       200       210       

             170       180       190       200       210       220 
pF1KE0 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
         .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.
NP_000 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
       220       230       240          250       260       270    

             230       240         250       260       270         
pF1KE0 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
       :. .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .  
NP_000 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
          280        290       300       310       320       330   

     280       290       300       310       320       330         
pF1KE0 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
         : ..:: . ..:   :  :.::  :: : :.:.:.  :.:   ::.      :..: .
NP_000 TGGFASEISSTVQE-ECFLNLEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMI
           340        350       360         370       380       390

     340 
pF1KE0 NI
       : 
NP_000 NY
         

>>NP_898871 (OMIM: 248600,248611) 2-oxoisovalerate dehyd  (392 aa)
 initn: 464 init1: 178 opt: 630  Z-score: 799.8  bits: 156.6 E(85289): 8.2e-38
Smith-Waterman score: 630; 34.4% identity (66.8% similar) in 331 aa overlap (13-340:69-391)

                                 10        20        30        40  
pF1KE0                   MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
                                     ..... .......:. : .:  . ..::.:
NP_898 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
       40        50        60        70        80        90        

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       : . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.
NP_898 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
       100       110       120       130       140       150       

            110       120        130       140       150       160 
pF1KE0 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
       ::..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : .
NP_898 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
       160       170       180       190       200       210       

             170       180       190       200       210       220 
pF1KE0 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
         .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.
NP_898 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
       220       230       240          250       260       270    

             230       240         250       260       270         
pF1KE0 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
       :. .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .  
NP_898 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
          280        290       300       310       320       330   

     280       290       300       310       320       330         
pF1KE0 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
         : ..:: . ..:   :  :.::  :: : :.:.:.  :.:   ::.      :..: .
NP_898 TGGFASEISSTVQE-ECFLNLEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMI
           340        350       360         370       380       390

     340 
pF1KE0 NI
       : 
NP_898 NY
         

>>XP_011534325 (OMIM: 248600,248611) PREDICTED: 2-oxoiso  (359 aa)
 initn: 464 init1: 178 opt: 561  Z-score: 712.9  bits: 140.4 E(85289): 5.7e-33
Smith-Waterman score: 561; 33.3% identity (67.3% similar) in 294 aa overlap (13-303:69-357)

                                 10        20        30        40  
pF1KE0                   MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
                                     ..... .......:. : .:  . ..::.:
XP_011 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
       40        50        60        70        80        90        

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       : . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.
XP_011 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
       100       110       120       130       140       150       

            110       120        130       140       150       160 
pF1KE0 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
       ::..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : .
XP_011 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
       160       170       180       190       200       210       

             170       180       190       200       210       220 
pF1KE0 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
         .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.
XP_011 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
       220       230       240          250       260       270    

             230       240         250       260       270         
pF1KE0 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
       :. .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .  
XP_011 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
          280        290       300       310       320       330   

     280       290       300       310       320       330         
pF1KE0 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
         : ..:: . .. .   .  : :                                    
XP_011 TGGFASEISSTVQMSVIQSVCDLPIL                                  
           340       350                                           

>>XP_005248813 (OMIM: 248600,248611) PREDICTED: 2-oxoiso  (360 aa)
 initn: 464 init1: 178 opt: 560  Z-score: 711.6  bits: 140.2 E(85289): 6.8e-33
Smith-Waterman score: 560; 33.9% identity (68.2% similar) in 286 aa overlap (13-295:69-349)

                                 10        20        30        40  
pF1KE0                   MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
                                     ..... .......:. : .:  . ..::.:
XP_005 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
       40        50        60        70        80        90        

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       : . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.
XP_005 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
       100       110       120       130       140       150       

            110       120        130       140       150       160 
pF1KE0 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
       ::..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : .
XP_005 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
       160       170       180       190       200       210       

             170       180       190       200       210       220 
pF1KE0 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
         .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.
XP_005 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
       220       230       240          250       260       270    

             230       240         250       260       270         
pF1KE0 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
       :. .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .  
XP_005 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
          280        290       300       310       320       330   

     280       290       300       310       320       330         
pF1KE0 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
         : ..:: . ..  :                                            
XP_005 TGGFASEISSTVQIYPHERTSVKFSVN                                 
           340       350       360                                 

>>XP_011534326 (OMIM: 248600,248611) PREDICTED: 2-oxoiso  (353 aa)
 initn: 464 init1: 178 opt: 559  Z-score: 710.4  bits: 139.9 E(85289): 7.8e-33
Smith-Waterman score: 559; 33.8% identity (68.7% similar) in 284 aa overlap (13-293:69-347)

                                 10        20        30        40  
pF1KE0                   MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
                                     ..... .......:. : .:  . ..::.:
XP_011 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
       40        50        60        70        80        90        

             50        60        70        80        90       100  
pF1KE0 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
       : . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.
XP_011 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
       100       110       120       130       140       150       

            110       120        130       140       150       160 
pF1KE0 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
       ::..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : .
XP_011 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
       160       170       180       190       200       210       

             170       180       190       200       210       220 
pF1KE0 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
         .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.
XP_011 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
       220       230       240          250       260       270    

             230       240         250       260       270         
pF1KE0 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
       :. .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .  
XP_011 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
          280        290       300       310       320       330   

     280       290       300       310       320       330         
pF1KE0 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
         : ..:: . ...                                              
XP_011 TGGFASEISSTVQQLEDTGD                                        
           340       350                                           




341 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:09:16 2016 done: Thu Nov  3 12:09:17 2016
 Total Scan time:  7.180 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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