Result of FASTA (omim) for pF1KB6887
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6887, 183 aa
  1>>>pF1KB6887 183 - 183 aa - 183 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4100+/-0.000283; mu= 9.6063+/- 0.018
 mean_var=123.6577+/-24.837, 0's: 0 Z-trim(122.5): 9  B-trim: 2170 in 1/51
 Lambda= 0.115336
 statistics sampled from 40614 (40623) to 40614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.476), width:  16
 Scan time:  6.300

The best scores are:                                      opt bits E(85289)
XP_011539778 (OMIM: 156790) PREDICTED: microfibril ( 183) 1313 228.3 5.5e-60
NP_059453 (OMIM: 156790) microfibrillar-associated ( 183) 1313 228.3 5.5e-60
NP_002394 (OMIM: 156790) microfibrillar-associated ( 183) 1313 228.3 5.5e-60
NP_001128720 (OMIM: 156790) microfibrillar-associa ( 182) 1296 225.4 3.9e-59
NP_001128719 (OMIM: 156790) microfibrillar-associa ( 182) 1296 225.4 3.9e-59
NP_001284639 (OMIM: 601103,616166) microfibrillar- ( 151)  293 58.5 5.9e-09
NP_001284638 (OMIM: 601103,616166) microfibrillar- ( 163)  293 58.5 6.3e-09
NP_001284640 (OMIM: 601103,616166) microfibrillar- ( 148)  287 57.5 1.2e-08
NP_003471 (OMIM: 601103,616166) microfibrillar-ass ( 173)  283 56.8 2.1e-08


>>XP_011539778 (OMIM: 156790) PREDICTED: microfibrillar-  (183 aa)
 initn: 1313 init1: 1313 opt: 1313  Z-score: 1197.9  bits: 228.3 E(85289): 5.5e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
              130       140       150       160       170       180

          
pF1KB6 GSC
       :::
XP_011 GSC
          

>>NP_059453 (OMIM: 156790) microfibrillar-associated pro  (183 aa)
 initn: 1313 init1: 1313 opt: 1313  Z-score: 1197.9  bits: 228.3 E(85289): 5.5e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
              130       140       150       160       170       180

          
pF1KB6 GSC
       :::
NP_059 GSC
          

>>NP_002394 (OMIM: 156790) microfibrillar-associated pro  (183 aa)
 initn: 1313 init1: 1313 opt: 1313  Z-score: 1197.9  bits: 228.3 E(85289): 5.5e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
              130       140       150       160       170       180

          
pF1KB6 GSC
       :::
NP_002 GSC
          

>>NP_001128720 (OMIM: 156790) microfibrillar-associated   (182 aa)
 initn: 1230 init1: 1230 opt: 1296  Z-score: 1182.6  bits: 225.4 E(85289): 3.9e-59
Smith-Waterman score: 1296; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182)

               10        20        30        40        50        60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
       :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAYLFLLFLP-GLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
     120       130       140       150       160       170         

          
pF1KB6 GSC
       :::
NP_001 GSC
     180  

>>NP_001128719 (OMIM: 156790) microfibrillar-associated   (182 aa)
 initn: 1230 init1: 1230 opt: 1296  Z-score: 1182.6  bits: 225.4 E(85289): 3.9e-59
Smith-Waterman score: 1296; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182)

               10        20        30        40        50        60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
       :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAYLFLLFLP-GLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
     120       130       140       150       160       170         

          
pF1KB6 GSC
       :::
NP_001 GSC
     180  

>>NP_001284639 (OMIM: 601103,616166) microfibrillar-asso  (151 aa)
 initn: 301 init1: 288 opt: 293  Z-score: 281.7  bits: 58.5 E(85289): 5.9e-09
Smith-Waterman score: 293; 51.4% identity (80.0% similar) in 70 aa overlap (85-154:51-119)

           60        70        80        90       100       110    
pF1KB6 PRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPC
                                     :.. :.    :.: .:.. ::::::.::: 
NP_001 DVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDD-LECWDEKFTCTRLYSVHRPV
               30        40        50         60        70         

          120       130       140       150       160       170    
pF1KB6 KQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAA
       :::....:: ::::.:..::::: : :: ..: .. .:::                    
NP_001 KQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPP
      80        90       100       110       120       130         

          180      
pF1KB6 SCARSCGSC   
                   
NP_001 CENVDLQRPNGL
     140       150 

>>NP_001284638 (OMIM: 601103,616166) microfibrillar-asso  (163 aa)
 initn: 302 init1: 288 opt: 293  Z-score: 281.3  bits: 58.5 E(85289): 6.3e-09
Smith-Waterman score: 293; 51.4% identity (80.0% similar) in 70 aa overlap (85-154:63-131)

           60        70        80        90       100       110    
pF1KB6 PRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPC
                                     :.. :.    :.: .:.. ::::::.::: 
NP_001 DVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDD-LECWDEKFTCTRLYSVHRPV
             40        50        60        70         80        90 

          120       130       140       150       160       170    
pF1KB6 KQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAA
       :::....:: ::::.:..::::: : :: ..: .. .:::                    
NP_001 KQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPP
             100       110       120       130       140       150 

          180      
pF1KB6 SCARSCGSC   
                   
NP_001 CENVDLQRPNGL
             160   

>>NP_001284640 (OMIM: 601103,616166) microfibrillar-asso  (148 aa)
 initn: 297 init1: 283 opt: 287  Z-score: 276.4  bits: 57.5 E(85289): 1.2e-08
Smith-Waterman score: 287; 44.4% identity (68.9% similar) in 90 aa overlap (65-154:29-116)

           40        50        60        70        80        90    
pF1KB6 YTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGP
                                     :  ..: : . :    :  :   .:.    
NP_001   MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQ-ATPETFTEDPNLVNDPATD-E
                 10        20        30         40        50       

          100       110       120       130       140       150    
pF1KB6 LDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCR
        .: .:.. ::::::.::: :::....:: ::::.:..::::: : :: ..: .. .:::
NP_001 TECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCR
         60        70        80        90       100       110      

          160       170       180      
pF1KB6 DKFSKCGVMASSGLCQSVAASCARSCGSC   
                                       
NP_001 QMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL
        120       130       140        

>>NP_003471 (OMIM: 601103,616166) microfibrillar-associa  (173 aa)
 initn: 297 init1: 283 opt: 283  Z-score: 271.9  bits: 56.8 E(85289): 2.1e-08
Smith-Waterman score: 283; 55.9% identity (84.7% similar) in 59 aa overlap (96-154:83-141)

          70        80        90       100       110       120     
pF1KB6 SQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYS
                                     .: .:.. ::::::.::: :::....:: :
NP_003 ATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTS
             60        70        80        90       100       110  

         130       140       150       160       170       180     
pF1KB6 LRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC  
       :::.:..::::: : :: ..: .. .:::                               
NP_003 LRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNG
            120       130       140       150       160       170  




183 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:12:22 2016 done: Sat Nov  5 00:12:23 2016
 Total Scan time:  6.300 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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